Selective Serotonin Reuptake Inhibitors: all 1,366 studies that test it

Page 6 of 14. Open to participants first (105), then studies with results posted, then the rest; newest registration first within each.

• Drug Therapy for Generalized Anxiety Disorder Among the ElderlyCompletedNCT00105586Phase 4Results posted
• Open-Label Study of Intramuscular Olanzapine Depot in Patients With Schizophrenia or Schizoaffective DisorderCompletedNCT00088465Phase 3Results posted
• Lexapro and Pramipexole and to Treat Major DepressionCompletedNCT00086307Phase 2Results posted
• Study of Antidepressants in Parkinson's DiseaseCompletedNCT00086190Phase 3Results posted
• Depression in Alzheimer's Disease-2CompletedNCT00086138Phase 2/3Results posted
• A Comparison of Fluoxetine and Divalproex for the Treatment of Intermittent Explosive DisorderCompletedNCT00078754Phase 2Results posted
• Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart FailureCompletedNCT00078286Phase 2/3Results posted
• Treatment of Depression in Parkinson's Disease TrialCompletedNCT00062738Phase 2Results posted
• Study of Pharmacotherapy of Psychotic DepressionCompletedNCT00056472Phase 3Results posted
• Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS)CompletedNCT00053703Phase 4Results posted
• Child and Adolescent Anxiety Disorders (CAMS)CompletedNCT00052078Phase 3Results posted
• Switching Medication to Treat SchizophreniaCompletedNCT00044655Phase 4Results posted
• Treatments for Depression: Drug Versus PsychotherapyCompletedNCT00043550Phase 3Results posted
• Pharmacological Intervention Project (Fluoxetine)CompletedNCT00027378Phase 2Results posted
• Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic DisordersCompletedNCT00001656Phase 4Results posted
• Antidepressant Treatment of Melancholia in Late LifeCompletedNCT00000378Phase 4Results posted
• Fosrolapitant and Palonosetron for Highly Emetogenic ADC-Induced Nausea and Vomiting in Solid TumorsActive, not recruitingNCT07841210Phase 2
• Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.Active, not recruitingNCT07518758Not applicable
• Treatment of Tinnitus With OlanzapineCompletedNCT07190482Phase 1
• Fluoxetine in Refractory Superior Mesenteric Artery Syndrome by Targeting Comorbid Somatic Symptom DisorderCompletedNCT07115472Not applicable
• The Effect of SSRIs on Threat of Shock Potentiated Neural CircuitryCompletedNCT07074652Not applicable
• Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIVWithdrawnNCT07007221Phase 2
• Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot StudyCompletedNCT07000734Phase 2
• Neurobiological Mechanisms of Pathological Rumination and Effects of AripiprazoleActive, not recruitingNCT06937476Not applicable
• Effect of Sertraline on Inflammation in Hemodialysis Patients with Depression: a Randomized Controlled TrialActive, not recruitingNCT06840379Not applicable
• To Determine the Effect of KP-001 on Rosuvastatin, Caffeine PK and the Effect of Fluvoxamine on KP-001 PK in VolunteersCompletedNCT06821698Phase 1
• Management of Acute Tinnitus With Migraine MedicationsActive, not recruitingNCT06799169Phase 4
• Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state.CompletedNCT06773767Phase 1
• Paroxetine Versus Placebo for Vasomotor Symptom Management in Surgical MenopauseCompletedNCT06763484Phase 2
• Fluoxetine for Refractory ConstipationCompletedNCT06750445Not applicable
• Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIVSuspendedNCT06705478Phase 2
• A Clinical Study to Evaluate the Drug Interaction Between YZJ-1139 Tablets and Escitalopram Oxalate TabletsCompletedNCT06680531Phase 1
• A Study of Olanzapine After Intranasal and Intramuscular AdministrationCompletedNCT06600477Phase 1
• Postoperative Pain Management Following Laparoscopic CholecystectomyCompletedNCT06561438Phase 3
• Detoxification From the Lipid TractCompletedNCT06357104Phase 4
• Fluoxetine in KCNC1-related DisorderCompletedNCT06341127Not applicable
• Effects of Antipsychotics on Brain Insulin Action in FemalesActive, not recruitingNCT06251635Not applicable
• Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy SubjectsCompletedNCT06232109Phase 1
• Paroxetine Safety and Efficacy in Rheumatoid ArthritisCompletedNCT06231745Phase 3
• Serotonin, Anxiety and Visceral SensationCompletedNCT06212284Not applicable
• Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychoticsCompletedNCT06200584Not applicable
• Effect of Olanzapine on Opioid Craving and Misuse Among Patients Receiving Opioids for Cancer-related Pain: A Pilot Double-Blind, Randomized Control TrialActive, not recruitingNCT06200181Phase 3
• Selective Serotonin Reuptake Inhibitors, Fluoxetine Versus the Standard Oral Desmopressin for Management of Mono-symptomatic Nocturnal Enuresis.Status unknownNCT06185361Not applicable
• Psychopharmacological Treatment of Emotional DistressWithdrawnNCT06133114Phase 4
• Efficacy and Safety of Sertraline in the Treatment of Maintenance Hemodialysis Patients With DepressionCompletedNCT06124417Phase 4
• A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet SyndromeCompletedNCT06118255Phase 3
• REward Processing And Citalopram StudyStatus unknownNCT06017037Phase 1/2
• Drug Interactions When DA-8010 is Co-administered With Paroxetine or Mirabegron in Healthy AdultsCompletedNCT05992428Phase 1
• Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy SubjectsCompletedNCT05964647Phase 1
• Sertraline Versus Escitalopram in South Asian Participants With Moderate to Severe Major Depressive DisorderCompletedNCT05950061Phase 3
• Improving Outcomes in Depression in Primary Care in a Low Resource SettingActive, not recruitingNCT05944926Phase 3
• A Study to Assess the Effects of Fluvoxamine on Savolitinib Exposure in Healthy Male SubjectsCompletedNCT05888207Phase 1
• A Study of Olanzapine in Patients With Acute AgitationStatus unknownNCT05803642Phase 3
• Effect of Citalopram on Chest Pain in Patients With Functional Chest PainTerminatedNCT05735756Phase 4
• Effects of Paroxetine on Cardiovascular Function in Septic PatientsCompletedNCT05725837Phase 2
• Efficacy and Safety of Oxybutynin Versus Paroxetine in Aromatase Inhibitor-induced Vasomotor SymptomsStatus unknownNCT05637671Phase 3
• Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)Active, not recruitingNCT05634707Early Phase 1
• Combined Antidepressant and Behavioural InterventionCompletedNCT05627154Not applicable
• Fenfluramine for Adult Dravet PatientsTerminatedNCT05560282Phase 3
• SMART Trial to Predict Anhedonia Response to Antidepressant TreatmentCompletedNCT05537584Phase 4
• Trial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive DisorderCompletedNCT05536414Phase 2
• A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)CompletedNCT05532358Phase 1
• Bioequivalence Study of Fluoxetine in Healthy Adult Subjects Under Fasting ConditionCompletedNCT05532332Phase 1
• Vortioxetine Adjunctive Treatment in Bipolar DepressionCompletedNCT05481957Phase 4
• Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid ArthritisCompletedNCT05480878Phase 3
• Single Dose Oral Bioequivalence Study of Vortioxetine Hemihydrobromide Orally Disintegrating TabletsCompletedNCT05417087Phase 1
• Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Patients With Advanced CancerWithdrawnNCT05403580Phase 3
• Evaluating the Results of Physician and Parent Decisions to Treat Selective Mutism With FluoxetineCompletedNCT05378711Phase 2
• Low Dose Olanzapine to the Prophylaxis of Nausea and Vomiting Induced by Chemotherapy in Children and AdolescentsStatus unknownNCT05346731Phase 3
• Comparison of Fluoxetine Versus Citalopram Therapy to Control Postmenopausal Vasomotor SyndromeCompletedNCT05346445Not applicable
• Sertraline Effect in Uremic PruritisCompletedNCT05341843Phase 2
• Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of TrazodoneWithdrawnNCT05299398Phase 1
• Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New GuineaWithdrawnNCT05283954Phase 2/3
• Predictors of Cognitive Outcomes in Geriatric DepressionActive, not recruitingNCT05273996Phase 4
• Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive DisorderCompletedNCT05271084Phase 1/2
• Risk of CYP2C19 Phenoconversion in Healthy Volunteers With Rapid, Normal, and Intermediate Predicted Metabolizers' StatusStatus unknownNCT05264142Phase 1
• Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular CancerStatus unknownNCT05244577Phase 3
• Olanzapine Anorexia CachexiaCompletedNCT05243251Phase 3
• Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic OutcomesCompletedNCT05232630Phase 4
• Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 ParosmiaWithdrawnNCT05216614Phase 2
• Evaluation of Trazodone in OSA-MCIActive, not recruitingNCT05209035Phase 4
• Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic EndometritisStatus unknownNCT05205993Phase 2
• The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCsStatus unknownNCT05202275Phase 2
• EEG Results of Deep TMS in Patients With OCDStatus unknownNCT05188833Not applicable
• Olanzapine in OUD PatientsWithdrawnNCT05179772Phase 2
• Effects of SERT Inhibition on the Subjective Response to LSD in Healthy SubjectsCompletedNCT05175430Phase 1
• A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive DisorderStatus unknownNCT05148169Phase 4
• A Comparative Study on Efficacy and Safety of add-on Sulforaphane or rTMS to Escitalopram for Major Depressive Disorder With Poor Response to Initial TreatmentStatus unknownNCT05145270Phase 4
• Fasted Bioequivalence Study of 2 Olanzapine Film-coated Tablets, 5 mg, in Healthy, Adult Male and Female Subjects.CompletedNCT05123976Phase 1
• Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464CompletedNCT05121714Phase 1
• Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive AbilitiesStatus unknownNCT05104918Phase 3
• Randomized-controlled Trial of the Effectiveness of COVID-19 Early Treatment in CommunityCompletedNCT05087381Phase 4
• RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ)WithdrawnNCT05085808Phase 4
• A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.Active, not recruitingNCT05064878Phase 3
• Antidepressant Efficacy of Psychotherapy and Citalopram in Patients With Breast Cancer and Major DepressionTerminatedNCT05063604Phase 2
• Fenfluramine and CognitionCompletedNCT05026398Phase 4
• Phase 1 Study of OLZ/SAM in Pediatric Subjects With Bipolar I DisorderCompletedNCT04987658Phase 1
• A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult ParticipantsCompletedNCT04981704Phase 1
• Sertraline Combined With Fluvoxamine in the Treatment of Refractory Obsessive-compulsive DisorderStatus unknownNCT04963257Phase 4
• Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer PatientsActive, not recruitingNCT04939090Phase 3

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