Nicotine: all 173 studies that test it

Page 1 of 2. Open to participants first (8), then studies with results posted, then the rest; newest registration first within each.

• Impact of Sweeteners on the Addictive Threshold of NicotineNot yet recruitingNCT07771725Phase 1
• Comparative Evaluation of Nicotine AnalogsRecruitingNCT07585006Phase 1
• Evaluating the Delivery and Effects of THC Vaping Liquids in the BloodstreamNot yet recruitingNCT06334016Early Phase 1
• Addictive Threshold of NicotineRecruitingNCT06096714Early Phase 1
• Evaluation of the Electronic Cigarette Withdrawal SyndromeRecruitingNCT06066996Early Phase 1
• Nicotine and Pavlovian BiasRecruitingNCT06027723Early Phase 1
• Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administrationRecruitingNCT05999383Phase 2
• Comparative Pharmacokinetics and Pharmacodynamics of Synthetic NicotineRecruitingNCT05962229Phase 1
• A Bioequivalence Study of 21 Milligram (mg) Nicotine Transdermal Patches (NicoDerm CQ, GlaxoSmithKline [GSK] Dungarvan) Compared to the Current Marketed 21 mg Nicotine Transdermal Patches (NicoDerm CQ, Alza) in Healthy Adult SmokersCompletedNCT05024747Phase 1Results posted
• Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit AttemptsCompletedNCT04994444Phase 2/3Results posted
• Nicotine's Potential Abuse With MentholCompletedNCT04535362Early Phase 1Results posted
• Effects of Menthol in E-cigarettes on Smoking BehaviorsCompletedNCT04521647Phase 1Results posted
• Depressed Mood Improvement Through Nicotine Dosing 2CompletedNCT04433767Phase 2Results posted
• Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE StudyCompletedNCT04231539Not applicableResults posted
• Behavioral Pharmacology of Cannabis and NicotineCompletedNCT04124432Phase 1Results posted
• Heart Rate Variability Biofeedback for Smoking CessationCompletedNCT03972137Phase 2Results posted
• Effects of Commonly Used Medications on Mood and ChoiceCompletedNCT03652740Phase 1Results posted
• Effects of E-Cigarette Flavors on Adults TCORS 2.0CompletedNCT03635333Phase 1Results posted
• Effects of E-cigarette Flavors on Youth TCORS 2.0CompletedNCT03634839Phase 1Results posted
• Nicotine Delivery Rate and Its Abuse Potential: Impact of MentholCompletedNCT03580525Early Phase 1Results posted
• Stress Neuroadaptation in Tobacco DependenceCompletedNCT03262233Phase 4Results posted
• Effects of Flavors on Nicotine Reinforcement in SmokersCompletedNCT03243630Early Phase 1Results posted
• Vaping THC From Electronic CigarettesCompletedNCT02955329Phase 3Results posted
• Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)CompletedNCT02873754Not applicableResults posted
• Mobile Contingency Management for Marijuana and Tobacco CessationCompletedNCT02869451Not applicableResults posted
• Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)CompletedNCT02816138Phase 4Results posted
• Babies Living Safe and SmokefreeCompletedNCT02602288Not applicableResults posted
• Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With AutismCompletedNCT02552147Phase 1Results posted
• Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement TherapyCompletedNCT02355665Phase 3Results posted
• Genetically Informed Smoking Cessation TrialCompletedNCT02351167Phase 4Results posted
• Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot StudyCompletedNCT02312934Phase 2Results posted
• Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot StudyCompletedNCT02265874Phase 1/2Results posted
• The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco UsersCompletedNCT02102100Not applicableResults posted
• Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety DisordersCompletedNCT01928758Not applicableResults posted
• Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic StatusCompletedNCT01928719Not applicableResults posted
• Project Quit: Positive vs. Negative Offers of an Online Stop Smoking ProgramCompletedNCT01923467Not applicableResults posted
• Comparison of Pharmacokinetic Profiles of Two Nicotine Gum FormulationsCompletedNCT01847443Phase 1Results posted
• Smoking Cessation After Hospitalization for a Cardiopulmonary IllnessCompletedNCT01791803Not applicableResults posted
• Nicotine Treatment of Cognitive Decline in Down SyndromeCompletedNCT01778946Phase 1/2Results posted
• Effects of Electronic Cigarettes on Nicotine ConcentrationsCompletedNCT01775787Not applicableResults posted
• Providing Free Nicotine Patches to Quitline SmokersCompletedNCT01736085Phase 3Results posted
• Nicotine Mouth Film for Craving Relief.CompletedNCT01702532Phase 3Results posted
• A Pharmacokinetic Evaluation of Two Nicotine Patches in SmokersCompletedNCT01702519Phase 1Results posted
• Pharmacokinetic Study of 4 mg Nicotine Lozenge.CompletedNCT01669122Phase 2Results posted
• Nicotine Related Brain Activity: The Influence of Smoking History and Blood Nicotine LevelsCompletedNCT01588561Not applicableResults posted
• Tailored Smoking Cessation Treatment for LIVE FOR LIFE® ParticipantsTerminatedNCT01560507Phase 2/3Results posted
• Nicotine Lozenge Bioequivalence StudyCompletedNCT01536704Phase 1Results posted
• Provoked Craving AssessmentCompletedNCT01506908Phase 2Results posted
• A Randomized Trial of Medi-Cal Beneficiaries Calling the California Smokers' HelplineCompletedNCT01502306Phase 3Results posted
• Nicotine Reinforcement and Aversion in Young Adult Light SmokersCompletedNCT01495819Early Phase 1Results posted
• A Smoking Cessation Trial in HIV-infected Patients in South AfricaCompletedNCT01484340Not applicableResults posted
• Provoked Craving Relief Study by NRTCompletedNCT01476202Phase 2Results posted
• Effect of the Electronic Cigarette on Withdrawal SymptomsCompletedNCT01454362Not applicableResults posted
• Nicotine Patch for Marijuana WithdrawalCompletedNCT01400243Phase 4Results posted
• Nicotine Replacement Therapy in the Intensive Care UnitCompletedNCT01362959Phase 4Results posted
• Behavioral Activation Intervention, Reward Processing, and Youth Smoking CessationCompletedNCT01351766Phase 3Results posted
• Nicotine Effects on Endophenotypes of SchizophreniaCompletedNCT01315002Not applicableResults posted
• Pharmacogenetics of Nicotine Addiction TreatmentCompletedNCT01314001Phase 3Results posted
• Concurrent Bupropion / Varenicline for Smoking CessationCompletedNCT01303861Phase 3Results posted
• Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit SmokingTerminatedNCT01296698Phase 3Results posted
• Smoking Cessation in Hospitalized SmokersCompletedNCT01289275Phase 4Results posted
• Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch MessagingCompletedNCT01287377Phase 3Results posted
• Nicotinic Modulation of the Default NetworkCompletedNCT01223404Not applicableResults posted
• Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product.CompletedNCT01084707Not applicableResults posted
• Single-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement ProductCompletedNCT01084603Not applicableResults posted
• Coping Skills Treatment for Smoking CessationCompletedNCT01061528Not applicableResults posted
• An Effectiveness Trial of Maintenance Therapy for Nicotine DependenceCompletedNCT01047527Phase 4Results posted
• Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco ReductionCompletedNCT01018394Phase 2/3Results posted
• Nicotine Vaccination and Nicotinic Receptor OccupancyCompletedNCT00996034Phase 2Results posted
• Efficacy and Safety Study of Nicotine Mint Lozenge (2mg and 4mg) in Smoking CessationCompletedNCT00985985Phase 3Results posted
• Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized CigarettesCompletedNCT00960778Phase 2Results posted
• Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and GenotypeCompletedNCT00894166Phase 3Results posted
• Oral Tolerability Of Two Nicotine Dosage FormsCompletedNCT00682461Phase 1Results posted
• Functional Magnetic Resonance Imaging (fMRI) Investigation of Nicotine Withdrawal SymptomsCompletedNCT00657020Phase 4Results posted
• Nicotine Patch Pretreatment for Smoking Cessation in PTSDCompletedNCT00625131Early Phase 1Results posted
• Varenicline and Nicotine Interactions in Humans (VA)CompletedNCT00606892Not applicableResults posted
• Nicotine and Behavior in Adult ADHDCompletedNCT00573248Not applicableResults posted
• A Randomized Trial of Internet Access to Nicotine PatchesCompletedNCT00534404Not applicableResults posted
• Analysis of Aldehyde Biomarkers of Exposure and Host ResponseTerminatedNCT00482690Not applicableResults posted
• Effect of Nicotine on Chronic Pelvic PainCompletedNCT00440505Phase 4Results posted
• Nicotine Lozenges for Treatment of Smokeless Tobacco AddictionCompletedNCT00392379Phase 3Results posted
• Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3CompletedNCT00390559Not applicableResults posted
• Nicotine as an Adjuvant Analgesic for Third Molar SurgeryCompletedNCT00385216Phase 4Results posted
• The Effects of Nicotine on Cognition in SchizophreniaCompletedNCT00383747Phase 4Results posted
• Anesthesia and Postoperative PainCompletedNCT00232817Phase 4Results posted
• Nicotine Delivery Systems: Research & TreatmentTerminatedNCT00108342Not applicableResults posted
• Comparing Smoking Treatment Programs for Lighter Smokers - 1CompletedNCT00086411Phase 2Results posted
• Maintaining Nonsmoking: Older Smokers - 1CompletedNCT00086385Phase 3Results posted
• Nicotine Virtual Reality Conditioned Place PreferenceWithdrawnNCT06259630Phase 4
• Assessing the Use of Nicotine Gum to Decrease Betel Nut Chewing in SaipanWithdrawnNCT05758298Early Phase 1
• Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) ExtensionCompletedNCT05746546Phase 2
• Depressed Mood Improvement Through Nicotine Dosing 3CompletedNCT05746273Phase 2
• IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery RateCompletedNCT05176418Early Phase 1
• E-cigarette Nicotine StudyCompletedNCT04709471Phase 2
• Do Flavors Increase the Addiction Potential of Nicotine?CompletedNCT04696380Phase 2
• Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized PatientsCompletedNCT04608201Phase 3
• Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit PatientsCompletedNCT04598594Phase 3
• Smoking by IV Pulsed NicotineCompletedNCT04488744Early Phase 1
• Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettesCompletedNCT04038515Phase 2
• Effects of Prazosin on the Attention-Enhancing Effects of NicotineWithdrawnNCT03416569Not applicable

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