Naltrexone: all 267 studies that test it

Page 1 of 3. Open to participants first (21), then studies with results posted, then the rest; newest registration first within each.

• Naltrexone for Nonsuicidal Self-InjuryNot yet recruitingNCT07641283Not applicable
• Evaluate the Efficacy and Safety of Naltrexone Hydrochloride Implant in Patients With Alcohol Use DisorderNot yet recruitingNCT07433413Phase 3
• A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery PatientsNot yet recruitingNCT07398404Phase 1/2
• Combination Therapy for Alcohol Use DisorderNot yet recruitingNCT07249554Phase 2
• Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery PatientsNot yet recruitingNCT07224087Phase 1
• Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)RecruitingNCT07224009Phase 2
• Individualized Pharmacological Approach to Obesity in Patients With Bipolar DisorderRecruitingNCT07213466Phase 4
• Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-CessationRecruitingNCT07092618Phase 2/3
• Trial to Evaluate the Effects of Naltrexone in Nonsuicidal Self-injuryNot yet recruitingNCT06622239Phase 2
• Improving Efficacity of Sleeve Gastrectomy With Naltrexone/Bupropion Extended-release TabletRecruitingNCT06620562Phase 4
• Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use DisorderRecruitingNCT06426303Phase 4
• Efficacy of Baclofen Vs Naltrexon in Achieving & Maintaining Abstinence in Alcohol Dependence.Not yet recruitingNCT06175507Not applicable
• Naltrexone and Propranolol Combined With ImmunotherapyRecruitingNCT05968690Phase 1
• Effectiveness of Low-dose Naltrexone in Patients With Different Types of VulvodyniaRecruitingNCT05955313Phase 2
• Exploring the PK of Different Doses of Naltrexone in Patients With AUDRecruitingNCT05919017Phase 1
• Emergency Department-Initiated Medications for Alcohol Use DisorderRecruitingNCT05827159Phase 3
• Evaluation of the O'Neil Long Acting Naltrexone Implant in Opioid Dependent PersonsNot yet recruitingNCT05382091Phase 2
• Bridging ED to Outpatient AUD Therapy With NaltrexoneNot yet recruitingNCT05228418Phase 4
• Low-Dose Naltrexone for the Treatment of Painful Diabetic NeuropathyRecruitingNCT04678895Phase 2
• Predicting Response to Naltrexone With Eye Tracking in Gaming DisorderRecruitingNCT04649892Phase 2
• Opioids and Social Support Enhanced Extinction EffectsEnrolling by invitationNCT04166071Early Phase 1
• Oral Naltrexone In Pediatric Eating DisordersTerminatedNCT05073679Phase 2/3Results posted
• Naltrexone NeuroimagingCompletedNCT04935931Early Phase 1Results posted
• Opioid Modulation and Neural Reward Activation in Healthy AdultsCompletedNCT04854551Phase 1/2Results posted
• Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSMCompletedNCT04791969Phase 2Results posted
• Impact of Colchicine and Low-dose Naltrexone on COVID-19CompletedNCT04756128Phase 2Results posted
• Pharmacokinetic Study of Vivitrol in Healthy ParticipantsCompletedNCT04716881Phase 1Results posted
• Inpatient Single Dose Interventions for Alcohol Use DisorderCompletedNCT04562779Early Phase 1Results posted
• Naltrexone Treatment for Prolonged Grief Disorder (PGD)TerminatedNCT04547985Phase 4Results posted
• EMI-EHP Weight Management and Type 2 Diabetes Pragmatic TrialTerminatedNCT04531176Phase 4Results posted
• Low-dose Naltrexone for Bladder Pain SyndromeTerminatedNCT04450316Phase 2Results posted
• Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19TerminatedNCT04365985Phase 2Results posted
• Study of Naltrexone-Induced Blockade of Antidepressant EffectsCompletedNCT04322526Phase 4Results posted
• A Novel Human Lab Model for Screening AUD MedicationsCompletedNCT04249882Phase 2Results posted
• Vivitrol Treatment for Cannabis Use DisorderTerminatedNCT04139668Phase 2Results posted
• Low-Dose Naltrexone in Combination With Standard Treatment in Women With EndometriosisTerminatedNCT03970330Phase 3Results posted
• Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-RespondersCompletedNCT03946111Phase 2/3Results posted
• The O'Neil Long Acting Naltrexone Implant (OLANI) Pharmacokinetic (PK)/Safety Study in Healthy VolunteersCompletedNCT03810495Phase 1Results posted
• Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic SubjectsCompletedNCT03660475Phase 2Results posted
• Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in ChildrenCompletedNCT03447782Phase 1/2Results posted
• The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major DepressionCompletedNCT03386448Phase 4Results posted
• Linking Infectious and Narcology Care-Part IICompletedNCT03290391Phase 4Results posted
• Comparing Treatments for HIV-Infected Opioid Users in an Integrated Care Effectiveness Study (CHOICES) Scale-UpCompletedNCT03275350Phase 2/3Results posted
• Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in SchizophreniaTerminatedNCT03132571Phase 2Results posted
• Low Dose Naltrexone for Chronic Pain From ArthritisCompletedNCT03008590Phase 2Results posted
• Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court SettingsCompletedNCT02978417Phase 4Results posted
• Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical HomeCompletedNCT02885311Phase 1/2Results posted
• An Open Label Trial of Bupropion and Naltrexone for Binge DrinkingCompletedNCT02842073Phase 2Results posted
• An fMRI Study of Opioid-related Changes in Neural ActivityCompletedNCT02818036Not applicableResults posted
• Naltrexone and Bupropion Combination on Obese,Smoking Patients With SchizophreniaCompletedNCT02736474Phase 4Results posted
• Combining Varenicline and Naltrexone for Smoking CessationCompletedNCT02698215Phase 2Results posted
• Evaluating Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Transitioning From Buprenorphine Maintenance Prior to First Dose of VIVITROLCompletedNCT02696434Phase 3Results posted
• Naltrexone/Bupropion Cardiovascular Outcomes StudyTerminatedNCT02638129Phase 4Results posted
• Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use DisorderCompletedNCT02461927Phase 1/2Results posted
• Glutamatergic Modulation to Facilitate Naltrexone Initiation in Opioid DependenceCompletedNCT02437344Phase 2Results posted
• Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM)CompletedNCT02330419Phase 2Results posted
• Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use DisordersCompletedNCT02322047Phase 2Results posted
• Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast CancerTerminatedNCT02137252Phase 2Results posted
• Injectable Pharmacotherapy for Opioid Use Disorders (IPOD)CompletedNCT02110264Phase 3Results posted
• Extended-Release Naltrexone vs. Buprenorphine for Opioid TreatmentCompletedNCT02032433Phase 4Results posted
• Naltrexone for Individuals of East Asian DescentCompletedNCT02026011Phase 2Results posted
• Extended-Release Naltrexone Opioid Treatment at Jail Re-EntryCompletedNCT01999946Phase 4Results posted
• The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy VolunteersCompletedNCT01999114Phase 1Results posted
• Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))CompletedNCT01993108Phase 4Results posted
• Accelerated Development of Additive Pharmacotherapy Treatment for Methamphetamine Use DisorderCompletedNCT01982643Phase 1/2Results posted
• Study of Human Non-Shivering Thermogenesis and Basal Metabolic RateCompletedNCT01950520Phase 2Results posted
• Harm Reduction With Pharmacotherapy (HaRP)CompletedNCT01932801Phase 2Results posted
• Nalrexone Facilitated Discontinuation of BuprenorphineCompletedNCT01895036Phase 1/2Results posted
• Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary CareCompletedNCT01893827Phase 4Results posted
• Low-Dose Naltrexone (LDN) for Depression Relapse and RecurrenceCompletedNCT01874951Phase 2Results posted
• An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder.CompletedNCT01873729Phase 4Results posted
• Naltrexone for Antipsychotic-Induced Weight GainCompletedNCT01866098Not applicableResults posted
• Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol DependenceCompletedNCT01856712Phase 3Results posted
• A Double-Blind Comparison of Naltrexone and Placebo in Adults With Attention Deficit Hyperactivity DisorderTerminatedNCT01721330Phase 4Results posted
• Prevention of Stimulant-Induced Euphoria With an Opioid Receptor AntagonistCompletedNCT01673594Phase 4Results posted
• Neuropharmacological Basis of Social Connection: The Role of OpioidsCompletedNCT01672723Not applicableResults posted
• Low Dose Naltrexone for Metastatic Melanoma, Castrate Resistant Prostate Cancer and Renal CancerTerminatedNCT01650350Phase 2Results posted
• Kappa-PET Imaging and Naltrexone in Alcohol Drinking BehaviorsCompletedNCT01625611Phase 1Results posted
• Clinical Trial to Reduce Drinking in Women With HIVCompletedNCT01625091Phase 3Results posted
• Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)TerminatedNCT01601704Phase 3Results posted
• Safety Study of Oxycodone Hydrochloride and Naltrexone Hydrochloride Extended-Release Capsules in Subjects With Moderate to Severe Chronic Noncancer PainCompletedNCT01428583Phase 3Results posted
• Cocaine Use Reduction With BuprenorphineCompletedNCT01402492Phase 2/3Results posted
• Treatment Strategy for Alcohol Use Disorders in Veterans With TBICompletedNCT01342549Phase 3Results posted
• Sweet Preference and Alcohol CravingCompletedNCT01296646Phase 2Results posted
• Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice PopulationsCompletedNCT01246401Phase 1/2Results posted
• Will Having Alcohol Treatment Improve Functioning?CompletedNCT01245647Phase 2Results posted
• Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and PreventionCompletedNCT01227044Phase 2/3Results posted
• N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol DependenceCompletedNCT01214083Phase 2Results posted
• Extended-Release Naltrexone for Opioid Relapse Prevention Following Release From JailCompletedNCT01180647Phase 3Results posted
• Pilot Study of Depot NTX in Homeless VeteransTerminatedNCT01155869Phase 4Results posted
• Investigation of Naltrexone for Pathological GamblingCompletedNCT01057862Phase 2Results posted
• Naltrexone and Hypoglycemia in Type 1 DiabetesCompletedNCT01053078Phase 1/2Results posted
• Naltrexone for Impulse Control Disorders in Parkinson's DiseaseCompletedNCT01052831Phase 4Results posted
• Naltrexone for At-Risk and Problem Drinking in Smoking Cessation TreatmentCompletedNCT00938886Phase 2Results posted
• Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for AlcoholismCompletedNCT00920829Phase 4Results posted
• Pharmacogenetic Response to Naltrexone For Alcohol DependenceCompletedNCT00831272Phase 4Results posted
• Understanding Treatment Response With Naltrexone Among White AlcoholicsCompletedNCT00817089Phase 4Results posted
• Pilot Trial of Naltrexone for Obesity in Women With SchizophreniaCompletedNCT00793780Not applicableResults posted
• Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt SiteCompletedNCT00781898Phase 2/3Results posted
• Naltrexone in the Treatment of TrichotillomaniaCompletedNCT00775229Phase 2Results posted

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