Modafinil: all 187 studies that test it

Page 1 of 2. Open to participants first (10), then studies with results posted, then the rest; newest registration first within each.

• Modafinil to Optimize the Performance of Cold-Stressed Sleep-Deprived PersonnelRecruitingNCT07830056Phase 4
• Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)RecruitingNCT07582458Phase 2/3
• Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNCT07568574Not applicable
• Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled TrialNot yet recruitingNCT07295834Phase 2
• Cognitive Strategies in Early Psychosis 2RecruitingNCT07263022Phase 3
• Cognitive Strategies in Early Psychosis 1RecruitingNCT07231497Phase 3
• Modafinil and Exercise for Post Stroke FatigueNot yet recruitingNCT06354985Phase 3
• Investigation of Locus Coeruleus Function in Sustained AttentionRecruitingNCT06041048Phase 4
• Central Nervous System Stimulants and Physical Function in Children With Cerebral PalsyNot yet recruitingNCT05675098Early Phase 1
• Modafinil to Improve FatiguabilityRecruitingNCT05333250Phase 1/2
• Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis FatigueCompletedNCT03621761Phase 4Results posted
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-925 Study in Sleep-Deprived Healthy AdultsCompletedNCT03522506Phase 1Results posted
• Modafinil for the Treatment of Alcohol Use DisordersCompletedNCT03424681Phase 2Results posted
• Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple SclerosisCompletedNCT03185065Phase 3Results posted
• Modafinil for Freezing of Gait (FOG) in Parkinson's Disease (PD)CompletedNCT03083132Phase 2Results posted
• Developing Adaptive Interventions for Cocaine Cessation and Relapse PreventionCompletedNCT02896712Phase 2Results posted
• The Treatment of Insomnia Comorbid With Sleep Disordered Breathing Using Armodafinil and/or Cognitive Behavioral Therapy for InsomniaCompletedNCT02552303Not applicableResults posted
• Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep ApneaTerminatedNCT02494102Phase 4Results posted
• Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese PatientsCompletedNCT02478580Phase 3Results posted
• Improving Therapeutic Learning in Depression: Proof of ConceptCompletedNCT02376257Phase 2Results posted
• Pain Expectations in Subjects With OsteoarthritisCompletedNCT02155257Phase 4Results posted
• Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated NocturiaCompletedNCT02151253Phase 2/3Results posted
• Antipsychotic Effects on Brain Function in SchizophreniaTerminatedNCT01913327Phase 4Results posted
• Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-StrokeCompletedNCT01896128Phase 2Results posted
• Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade GliomaCompletedNCT01781468Phase 3Results posted
• Modafinil for Smoked Cocaine Self-AdministrationCompletedNCT01778010Phase 2Results posted
• A Phase II Study of Minocycline and Armodafinil for Reducing the Symptom Burden Produced by Chemoradiation Treatment for Esophageal CancerCompletedNCT01746043Phase 2Results posted
• Armodafinil for Patients Starting Hepatitis C Virus TreatmentTerminatedNCT01470651Phase 4Results posted
• Effect of Nuvigil on FatigueCompletedNCT01460628Phase 4Results posted
• Nuvigil or Placebo in Newly Diagnosed Malignant GliomaTerminatedNCT01400958Phase 2Results posted
• Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain TumorCompletedNCT01381718Phase 2Results posted
• Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer TherapyTerminatedNCT01348607Phase 2Results posted
• Single Agent Armodafinil for Patient-Reported Fatigue Following Radiation Therapy for Head and Neck CancerCompletedNCT01330446Phase 1/2Results posted
• A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and ArmodafinilCompletedNCT01317550Not applicableResults posted
• Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/Day) as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I DisorderCompletedNCT01305408Phase 3Results posted
• Symptom Burden in Head and Neck CancerTerminatedNCT01219673Phase 1/2Results posted
• Treatment of Apathy in Alzheimer's Disease With ModafinilCompletedNCT01172145Phase 3Results posted
• Nuvigil in Treatment of Cancer-Related Fatigue in Chronic Myeloid Leukemia PatientsTerminatedNCT01169753Not applicableResults posted
• A Study of the Effectiveness of Armodafinil to Treat Cancer-Related Fatigue in Patients With Multiple MyelomaCompletedNCT01160380Phase 3Results posted
• Modafinil, Sleep Architecture and Cocaine RelapseCompletedNCT01137396Phase 2Results posted
• Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I DisorderTerminatedNCT01121536Phase 3Results posted
• Cognitive Behavioral Therapy +/- Armodafinil for Insomnia and Fatigue Following ChemotherapyCompletedNCT01091974Phase 2Results posted
• Identifying and Treating Arousal Related Deficits in Neglect and DysphagiaCompletedNCT01085903Phase 2Results posted
• Efficacy and Tolerability of Armodafinil in Adults With Excessive Sleepiness Associated With Shift Work DisorderCompletedNCT01080807Phase 4Results posted
• A Study to Evaluate the Efficacy and Safety of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I DisorderCompletedNCT01072929Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I DisorderCompletedNCT01072630Phase 3Results posted
• Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain TumorsCompletedNCT01032200Phase 2Results posted
• "Pilot Study of Armodafinil in Patients With Dementia With Lewy Bodies"CompletedNCT01023672Phase 4Results posted
• Management of Insomnia in Breast Cancer PatientsCompletedNCT01011218Phase 2Results posted
• Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain InjuryTerminatedNCT00983437Phase 3Results posted
• Impact of Armodafinil on Neurocognition and Cognitive Fatigue in Multiple Sclerosis (MS)CompletedNCT00981084Phase 2/3Results posted
• Study to Evaluate the Efficacy and Safety of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain InjuryTerminatedNCT00893789Phase 3Results posted
• Modafinil for Methamphetamine DependenceTerminatedNCT00859573Phase 2Results posted
• Pharmacotherapy & CM for Opioid and Cocaine DependenceCompletedNCT00838981Phase 1/2Results posted
• Safety and Efficacy of Armodafinil for Fatigue Associated With Taxanes Alone or in Combination With Other AgentsTerminatedNCT00825227Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Armodafinil as Adjunctive Therapy in Adults With SchizophreniaCompletedNCT00772005Phase 2Results posted
• A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients With Malignant GliomasCompletedNCT00766467Phase 2Results posted
• Study of the Effect of Armodafinil Treatment in Healthy Subjects With Excessive Sleepiness Associated With Jet Lag DisorderCompletedNCT00758498Phase 3Results posted
• Effects of Modafinil in Methamphetamine DependenceCompletedNCT00751023Phase 4Results posted
• Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDSCompletedNCT00737204Phase 4Results posted
• Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory PerformanceCompletedNCT00711516Phase 4Results posted
• Modafinil Effects on Cognition in Schizophrenia PatientsCompletedNCT00711464Phase 4Results posted
• An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia FatigueCompletedNCT00678691Phase 4Results posted
• Modafinil Treatment for Sleep/Wake Disturbances in Older AdultsTerminatedNCT00626210Phase 4Results posted
• Modafinil for Treatment of Fatigue in ALS PatientsCompletedNCT00614926Phase 4Results posted
• Stress and Medication Effects on Cocaine Cue ReactivityCompletedNCT00613015Phase 2Results posted
• PET Study Examining the Dopaminergic Activity of Armodafinil in AdultsCompletedNCT00592943Phase 1/2Results posted
• Use of Modafinil in the Treatment of TinnitusTerminatedNCT00591019Phase 1Results posted
• Modafinil, Sleep, and Cognition in Cocaine DependenceCompletedNCT00582491Not applicableResults posted
• Safety and Tolerability of Modafinil for Methamphetamine DependenceCompletedNCT00569374Phase 2Results posted
• Phase 2, Multi-Center Trial of Modafinil for Methamphetamine DependenceCompletedNCT00520286Phase 2Results posted
• Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and DepressionCompletedNCT00518986Phase 4Results posted
• Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive DeficitsCompletedNCT00487942Phase 2Results posted
• Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I DisorderCompletedNCT00481195Phase 2Results posted
• Modafinil vs Placebo for the Treatment of Methamphetamine DependenceCompletedNCT00469508Phase 2Results posted
• Modafinil for Treatment of Cognitive Dysfunction in SchizophreniaCompletedNCT00423943Phase 4Results posted
• Effects of Methylphenidate Versus Sustained Release Methylphenidate on Cognitive FunctioningTerminatedNCT00418691Phase 3Results posted
• Effects of Armodafinil on Cognition for Patients With Schizophrenia or Schizoaffective DisorderCompletedNCT00373672Phase 4Results posted
• Modafinil Treatment for Cocaine Dependence and HIV High-Risk BehaviorCompletedNCT00368290Phase 2Results posted
• Study of the Efficacy and Multiple-Dose Plasma Concentration-Time Profiles of Armodafinil and PROVIGILCompletedNCT00236080Phase 3Results posted
• Post-Traumatic Brain Injury (Post-TBI) Fatigue and Its TreatmentTerminatedNCT00233090Phase 2Results posted
• Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea SyndromeCompletedNCT00228566Phase 3Results posted
• Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1CompletedNCT00218387Phase 2Results posted
• Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent IndividualsCompletedNCT00218062Phase 2Results posted
• Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8TerminatedNCT00218036Phase 2Results posted
• Medications for Stopping Cocaine Dependence and Preventing RelapseCompletedNCT00218023Phase 2Results posted
• Modafinil and Naltrexone to Reduce Cocaine and Alcohol DependenceCompletedNCT00142818Phase 2Results posted
• Modafinil Treatment for Cocaine-Dependent IndividualsCompletedNCT00129285Phase 2Results posted
• Effectiveness of Modafinil for Treating Fatigue in Adults With HIV/AIDSCompletedNCT00118378Phase 4Results posted
• Safety/Efficacy Study With Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Chronic SWSDCompletedNCT00080288Phase 3Results posted
• Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) SyndromeCompletedNCT00079677Phase 3Results posted
• Safety and Efficacy Study of Armodafinil (CEP-10953) in the Treatment of Excessive Sleepiness Associated With NarcolepsyCompletedNCT00078377Phase 3Results posted
• Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome(OSAHS)CompletedNCT00078325Phase 3Results posted
• Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep DisorderCompletedNCT00078312Phase 3Results posted
• Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in NarcolepsyCompletedNCT00066170Phase 3Results posted
• Reliability of Standardized IQ Testing Under Modafinil, Racetam-Class Compounds, Sleep Restriction and Daily ActivityCompletedNCT07852130Phase 1
• Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From AnesthesiaCompletedNCT07128719Not applicable
• A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005)CompletedNCT06665230Phase 1
• A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003)CompletedNCT06619665Phase 1
• RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)CompletedNCT06404099Phase 2

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