Methylphenidate: all 321 studies that test it

Page 1 of 4. Open to participants first (35), then studies with results posted, then the rest; newest registration first within each.

• Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder and Cannabis Use DisorderNot yet recruitingNCT07838311Phase 4
• The Efficacy of a Pharmacological Treatment (Reboxetine Plus Ritalin) Versus Dog-Assisted Therapy in PTSDRecruitingNCT07771530Phase 2
• Evaluation of Foquest in Adults 65 Years and Older With ADHDRecruitingNCT07710014Phase 4
• EEG Biomarkers for ADHD Stimulant TreatmentNot yet recruitingNCT07650643Phase 4
• Medication Treatment of ADHD in Pediatric EpilepsyRecruitingNCT07594652Phase 4
• Treating Young Children With Attention Deficit Hyperactivity DisorderRecruitingNCT07300956Phase 4
• Combined Brain Stimulation and Methylphenidate Treatment for Apathy in DementiaRecruitingNCT07279740Phase 2
• Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell DiseaseRecruitingNCT07226219Phase 1
• A Multimodal Imaging Study of Dopamine in Early PsychosisNot yet recruitingNCT06977308Phase 1
• Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related FatigueRecruitingNCT06905587Phase 3
• The Effects of Methylphenidate on Symptomatology in Individuals With Borderline Personality DisorderNot yet recruitingNCT06759298Early Phase 1
• Precision Care for Major Depressive DisorderEnrolling by invitationNCT06580041Phase 4
• An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early EveningRecruitingNCT06577779Phase 4
• Methylphenidate in KBG Syndrome: N-of-1 SeriesRecruitingNCT06465641Phase 4
• Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.RecruitingNCT06369714Not applicable
• Lisdexamphetamine Vs Methylphenidate for Pediatric Patients with ADHD and Type 1 DiabetesRecruitingNCT05957055Phase 2
• The Role of the Brain in Mental and Physical FatigueRecruitingNCT05880342Phase 3
• Benefits of ADHD Treatment in Detained PeopleRecruitingNCT05842330Phase 3
• Methylphenidate for the Treatment of PTSD With Associated Neurocognitive ComplaintsRecruitingNCT05776056Phase 4
• Oxygen Toxicity: Mechanisms in HumansRecruitingNCT05761756Not applicable
• Central Nervous System Stimulants and Physical Function in Children With Cerebral PalsyNot yet recruitingNCT05675098Early Phase 1
• Methylphenidate for Apathy in Veterans With Parkinson's DiseaseNot yet recruitingNCT05669170Phase 2
• rTMS for Apathy Clinical TrialRecruitingNCT05561205Not applicable
• Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual DisabilitiesEnrolling by invitationNCT05301361Phase 1
• The Role of Brain Dopamine in Chronic PainRecruitingNCT05285683Phase 2
• Efficacy of Reboxetine and Methylphenidate Treatment on Attentional, Sensory and Emotional Dysregulation in Adults With PTSDRecruitingNCT05133804Phase 2
• Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHDRecruitingNCT04781972Phase 4
• Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity DisorderRecruitingNCT04421248Phase 4
• Methylphenidate for the Treatment of Epilepsy-related Cognitive DeficitsRecruitingNCT04419272Phase 4
• The Effects of a Single Dose of Methylphenidate on Motor PerformanceRecruitingNCT04283604Phase 4
• Differences by Sex and Genotype in the Effects of Stress on Executive FunctionsRecruitingNCT04273880Phase 1
• Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD RiskRecruitingNCT03781765Phase 4
• Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHDRecruitingNCT03781752Phase 4
• Methylphenidate in Adults With Attention Deficit/Hyperactivity DisorderRecruitingNCT02951754Phase 4
• The Psychiatric and Cognitive Phenotypes in Velocardiofacial SyndromeRecruitingNCT00768820Phase 4
• Safety and Tolerability Study of Adhansia XR® Extended-Release Capsules in ChildrenTerminatedNCT04987762Phase 4Results posted
• Methylphenidate for Ptsd and Stroke VeteransCompletedNCT04885257Phase 1/2Results posted
• Cannabidiol and CES1 Interactions in Healthy SubjectsCompletedNCT04603391Phase 4Results posted
• Real-World Evidence of Duration of Effect of Adhansia XR (Extended-Release) for Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD)TerminatedNCT04507204Phase 4Results posted
• Large-scale Brain Organization During Cognitive Control in ADHDCompletedNCT04349917Phase 4Results posted
• Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of ConsciousnessActive, not recruitingNCT03814356Phase 1Results posted
• A Pilot of Methylphenidate in Mild Cognitive Impairment and Dementia Participants.CompletedNCT03811847Phase 4Results posted
• Effects of Commonly Used Medications on Mood and ChoiceCompletedNCT03652740Phase 1Results posted
• PRC-063 Adult Laboratory Classroom Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)CompletedNCT03618030Phase 3Results posted
• Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRICompletedNCT03326245Phase 1Results posted
• Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple SclerosisCompletedNCT03185065Phase 3Results posted
• PRC-063 Classroom Study in Children (6-12 Years of Age) With ADHDCompletedNCT03172481Phase 3Results posted
• A Flexible-Dose Titration Study of Aptensio XR in Children Ages 4 to Under 6 Years Diagnosed With ADHDCompletedNCT02683265Phase 4Results posted
• A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Naturalistic SettingCompletedNCT02520388Phase 3Results posted
• Intervention for Teens With ADHD and Substance UseTerminatedNCT02502799Phase 3Results posted
• A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom SettingCompletedNCT02493777Phase 3Results posted
• Apathy in Dementia Methylphenidate Trial 2CompletedNCT02346201Phase 3Results posted
• General Anesthesia Emergence Induced by MethylphenidateCompletedNCT02327195Phase 1Results posted
• The Effects of ADHD Medication (TEAM) StudyCompletedNCT02293655Phase 4Results posted
• Dose Response Effects of Quillivant XR in Children With ADHD and Autism: A Pilot StudyCompletedNCT02255565Phase 4Results posted
• Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBICompletedNCT02225106Phase 2Results posted
• Methylphenidate Treatment of Attention Deficits in EpilepsyCompletedNCT02178995Phase 4Results posted
• Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. AnxietyCompletedNCT02153944Phase 4Results posted
• Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO PETTerminatedNCT02152670Not applicableResults posted
• The Efficacy and Safety of PRC-063 in Adult ADHD PatientsCompletedNCT02139124Phase 3Results posted
• Reversal of General Anesthesia With MethylphenidateCompletedNCT02051452Phase 1/2Results posted
• Examining Tolerance to CNS Stimulants in ADHDCompletedNCT02039908Phase 4Results posted
• Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))CompletedNCT01993108Phase 4Results posted
• A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) ParticipantsCompletedNCT01933880Phase 4Results posted
• Methylphenidate for Attention Problems After Pediatric TBICompletedNCT01933217Phase 4Results posted
• Gene-environment Interactions and Brain Functional Connectivity in Attention Deficit Hyperactivity DisorderCompletedNCT01912352Not applicableResults posted
• Pharmacokinetics of HLD200 in Children and Adolescents With ADHDCompletedNCT01907360Phase 1/2Results posted
• Methylphenidate to Improve Balance and Walking in MSCompletedNCT01896700Phase 2/3Results posted
• Behavioral Differences in Effortful ControlCompletedNCT01852344Not applicableResults posted
• Exploring the Use of Transdermal Methylphenidate to Reduce Fall Risk in Patients With Dementia.TerminatedNCT01825577Phase 4Results posted
• Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based ApproachCompletedNCT01678209Phase 4Results posted
• Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With CancerActive, not recruitingNCT01628029Phase 2Results posted
• Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer TherapyTerminatedNCT01348607Phase 2Results posted
• Time Course of Response to Methylphenidate HCl ER Capsules in Children 6 to 12 Years With ADHD in Classroom SettingCompletedNCT01269463Phase 3Results posted
• Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHDCompletedNCT01239030Phase 3Results posted
• Response Variability in Children With Attention Deficit Hyperactivity Disorder (ADHD)CompletedNCT01238822Phase 4Results posted
• SPD544 High Strength Bioequivalence StudyCompletedNCT01183234Phase 1Results posted
• Methylphenidate for Cancer-Related FatigueTerminatedNCT01164956Phase 1Results posted
• Interventions for Children With Attention and Reading DisordersCompletedNCT01133847Phase 4Results posted
• Apathy in Dementia Methylphenidate Trial (ADMET)CompletedNCT01117181Phase 2Results posted
• Effects of Methylphenidate on Attention Deficits in Childhood Cancer SurvivorsTerminatedNCT01100658Not applicableResults posted
• Enhancing Attention in Adults With Compulsive HoardingCompletedNCT01100268Phase 2Results posted
• Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response PotentialsCompletedNCT01063153Phase 4Results posted
• An Efficacy Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention-Deficit/Hyperactivity Disorder (ADHD)CompletedNCT01060150Phase 4Results posted
• Study of the Effect of Individualizing Daytrana Wear-times on Sleep in Children With ADHDCompletedNCT00989950Not applicableResults posted
• Adult Study / OROS Methylphenidate Hydrochloride (HCL) (OROS MPH) in Adults With Attention Deficit Hyperactivity Disorder (ADHD)CompletedNCT00937040Phase 4Results posted
• Quillivant Oral Suspension (Quillivant XR) in the Treatment of Attention Deficit Hyperactivity Disorder (ADHD)CompletedNCT00904670Phase 3Results posted
• A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy VolunteersCompletedNCT00901576Phase 1Results posted
• Comparing the Effectiveness of New Versus Older Treatments for Attention Deficit Hyperactivity Disorder (The NOTA Study)CompletedNCT00889915Phase 4Results posted
• Study to Evaluate the Efficacy and Quality of Life of Long-Acting Methylphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD)CompletedNCT00783835Phase 4Results posted
• Evaluating the Methylphenidate Patch to Treat Former Stimulant Users With ADHDCompletedNCT00780208Not applicableResults posted
• The Impact of Osmotic Release Oral Delivery System Methylphenidate (OROS MPH) Upon Family of Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)CompletedNCT00758160Phase 4Results posted
• Long Acting Stimulant Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Young ChildrenCompletedNCT00754208Phase 4Results posted
• Neurobiological Principles Applied to the Rehabilitation of Stroke PatientsCompletedNCT00715520Not applicableResults posted
• Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With DepressionCompletedNCT00602290Phase 4Results posted
• Proton Magnetic Spectroscopy in Children and Adolescents With ADHD Before and After Treatment With OROS MethylphenidateCompletedNCT00593112Phase 4Results posted
• Study of Medication Patch to Treat Children Ages 6-12 With ADHDCompletedNCT00586157Phase 4Results posted
• Learning Impairments Among Survivors of Childhood CancerCompletedNCT00576472Phase 4Results posted
• Quetiapine and Concerta in the Treatment for ADHD and Aggressive Behavior.CompletedNCT00550147Phase 2Results posted
• Testing Methylphenidate for Smoking AbstinenceCompletedNCT00549640Phase 2Results posted

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