Metformin: all 1,377 studies that test it

Page 7 of 14. Open to participants first (169), then studies with results posted, then the rest; newest registration first within each.

• Dapagliflozin Versus Metformin and Their Combination in Polycystic Ovary SyndromeCompletedNCT05601336Phase 3
• Effect of Metformin, Dapagliflozin, Combination of Metformin and Pioglitazone in Patients With Type 2 DiabetesStatus unknownNCT05591235Phase 3
• Metformin Treatment in Infants After Perinatal Brain InjuryTerminatedNCT05590676Phase 1
• A Study of LY3526318 in Healthy Male Japanese ParticipantsWithdrawnNCT05580250Phase 1
• Effect of Metformin Use on Mortality in Diabetic and Non Diabetic Patients With Sepsis and Septic Shock.Status unknownNCT05572060Not applicable
• A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome.CompletedNCT05571319Phase 2
• Maternal and Fetal Outcome With Metformin Therapy for Obese Pregnant Women .TerminatedNCT05554679Phase 4
• Metformin in Patients With Ulcerative Colitis Treated With MesalamineCompletedNCT05553704Phase 2
• Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy ParticipantsCompletedNCT05550129Phase 1
• Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin TherapyStatus unknownNCT05545800Phase 3
• Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant LesionsTerminatedNCT05536037Phase 1
• Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty LiverCompletedNCT05521633Phase 3
• Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.Status unknownNCT05519813Phase 4
• Non-alcoholic Fatty Liver Disease and Its TreatmentCompletedNCT05480007Not applicable
• Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of PregnancyCompletedNCT05479214Phase 4
• GXR RM China BE Study (Darmstadt - Jiangsu)CompletedNCT05463094Phase 1
• Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow RidgeStatus unknownNCT05418452Phase 3
• Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease ProgressionCompletedNCT05373680Phase 2/3
• Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer PatientsCompletedNCT05351021Phase 2
• Metformin Treatment in Progressive Multiple SclerosisCompletedNCT05349474Early Phase 1
• The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.CompletedNCT05332795Not applicable
• Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic LeukemiaStatus unknownNCT05326984Not applicable
• Metformin Use in Cardiac Fibrosis in PAI-1 DeficiencyActive, not recruitingNCT05317806Phase 4
• Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis PatientsStatus unknownNCT05298670Phase 2
• Longitudinal Follow-up in Women With Endometrial Hyperplasia Without AtypiaCompletedNCT05292573Phase 3
• Metformin Efficacy and Safety for Gastric Intestinal MetaplasiaCompletedNCT05288153Phase 4
• A Pragmatic Approach to Lower Diabetes Risk After Gestational DiabetesCompletedNCT05280496Phase 3
• Evaluation and Intervention of Cognitive Function in Patients With Diabetes Mellitus.Status unknownNCT05262257Early Phase 1
• The POWERED Study: Prophylaxis With Metformin to Prevent PTDMCompletedNCT05240274Phase 2
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and DolutegravirCompletedNCT05236530Phase 1
• Paxalisib With a High Fat, Low Carb Diet and Metformin for GlioblastomaCompletedNCT05183204Phase 2
• Efficacy of Metformin as add-on Therapy in Non-Diabetic Heart Failure PatientsCompletedNCT05177588Phase 4
• Monitoring Parameters Beyond Glycemic Control: Impact of Sitagliptin on Quality of Life in Type 2 Diabetes PatientsCompletedNCT05167513Phase 4
• Molecular Effects of Aspirin & Metformin on Colonic EpitheliumWithdrawnNCT05158374Not applicable
• Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)CompletedNCT05132023Phase 1
• CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying TherapyCompletedNCT05131828Phase 2
• Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female VolunteersCompletedNCT05125575Phase 1
• Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female VolunteersCompletedNCT05124730Phase 1
• Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female VolunteersCompletedNCT05123781Phase 1
• Metformin in Children With Fragile X SyndromeCompletedNCT05120505Phase 4
• Metformin for Older Patients With Heart Failure With Preserved Ejection FractionCompletedNCT05093959Phase 2
• A Study of Lazertinib (JNJ-73841937) in Healthy ParticipantsCompletedNCT05076877Phase 1
• Implication of Metformin Plus Aromatase Inhibitor in Obese Postmenopausal Breast Cancer WomenCompletedNCT05053841Phase 2
• Anti-diabetic Drugs and Fatty Liver ManagementStatus unknownNCT05041673Not applicable
• Effect of Metformin on Patients With OsteoarthritisStatus unknownNCT05034029Not applicable
• Metformin and Nightly Fasting in Women With Early Breast CancerActive, not recruitingNCT05023967Phase 2
• Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT)CompletedNCT05013112Not applicable
• A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2)CompletedNCT04998032Phase 2/3
• Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and AnxietyStatus unknownNCT04984070Not applicable
• Pemvidutide (ALT-801) DDI Study in Healthy VolunteersCompletedNCT04972396Phase 1
• Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung CancerActive, not recruitingNCT04931017Phase 2
• The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate CancerStatus unknownNCT04926155Phase 2
• The Effect of Metformin in Patients With Newly Diagnosed mHSPCActive, not recruitingNCT04925063Phase 2
• Comparative Effects of Metformin and Insulin on Stereological Studies and Immunohistochemistry of PlacentaCompletedNCT04907708Not applicable
• Metformin for the Prevention of CRA RecurrenceStatus unknownNCT04885426Not applicable
• Effect of Metformin in Children With Type 1 DiabetesCompletedNCT04879511Phase 2/3
• Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese SubjectsCompletedNCT04877106Phase 1
• A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy SubjectsCompletedNCT04859452Phase 1
• Prevention of Pre-eclampsia Using Metformin: a Randomized Control TrialStatus unknownNCT04855513Not applicable
• A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride TabletsStatus unknownNCT04841720Phase 1
• Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment FailureCompletedNCT04841096Phase 3
• The Effect and the Pharmacogenomics Study of Liraglutide in Obese PatientsWithdrawnNCT04839237Phase 2
• TEsting METformin Against Cognitive Decline in HDCompletedNCT04826692Phase 3
• Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial CancerStatus unknownNCT04792749Phase 3
• Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)Status unknownNCT04780854Phase 2
• The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee OsteoarthritisWithdrawnNCT04767841Phase 1/2
• Metformin in Diabetic Patients Undergoing Coronary AngiographyStatus unknownNCT04766008Phase 4
• Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative ColitisStatus unknownNCT04750135Phase 2
• An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood CancerActive, not recruitingNCT04742751Phase 2
• Metformin Use to Reduce Disparities in Newly Diagnosed Breast CancerWithdrawnNCT04741204Phase 4
• A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic ImagingActive, not recruitingNCT04691960Phase 2
• Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting GlucoseStatus unknownNCT04662866Phase 2
• Counteracting Deleterious Metabolic Glucocorticoid Effects With MetforminCompletedNCT04659915Phase 4
• Metformin for the Treatment of Hidradenitis Suppurativa (HS)CompletedNCT04649502Phase 3
• Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin HydrochlorideCompletedNCT04621669Phase 1
• A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes MellitusStatus unknownNCT04615351Phase 3
• Metformin Plus Megestrol Acetate As a Fertility-sparing Treatment in Patients with Atypical Endometrial HyperplasiaTerminatedNCT04607252Phase 2/3
• Pilot Study Into the Use of Metformin and LDN for Patients With COVID-19WithdrawnNCT04604678Phase 2
• Impact of Metformin on Peripheral Arterial Calcification in Type 1 DiabetesActive, not recruitingNCT04583462Phase 3
• Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial CancerActive, not recruitingNCT04576104Phase 2
• The Effect of Metformin on Breast Cancer PatientsStatus unknownNCT04559308Phase 2
• The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With PrediabetesCompletedNCT04549415Phase 4
• Oral Metformin for Treatment of ABCA4 RetinopathyActive, not recruitingNCT04545736Phase 1/2
• Metformin Versus Standard of Care Treatment in Pregnant Women With PrediabetesWithdrawnNCT04523363Phase 4
• Metformin's Effect on Drug Metabolism in Patients With Type 2 DiabetesTerminatedNCT04504045Phase 1
• Effect of Metformin on Non PCO Women Undergoing IVF/ICSICompletedNCT04489147Not applicable
• A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of MeforminCompletedNCT04448821Phase 1
• A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.CompletedNCT04428086Phase 1
• Effect of Metformin on Gut Microbiota Changes and Glycemic Control of Newly Diagnosed Type 2 DiabetesCompletedNCT04426422Phase 4
• Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist StudyCompletedNCT04409795Phase 2/3
• Anti-inflammatory Status in DM2 Treated PatientsStatus unknownNCT04392557Phase 4
• Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 DiabetesStatus unknownNCT04390295Phase 3
• Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.Status unknownNCT04387630Phase 2/3
• Metformin in Dengue With ObesityCompletedNCT04377451Phase 1/2
• Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.Active, not recruitingNCT04341571Phase 2
• Metformin to Treat Corticosteroids-induced HyperglycemiaCompletedNCT04332393Phase 4
• Bioequivalence Study for Fixed Dose Combination Zemimet® SR Tab. 50/1000 and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.CompletedNCT04317703Phase 1
• Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 DiabetesStatus unknownNCT04298684Phase 4
• Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic AgentsStatus unknownNCT04287387Phase 4
• Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac SurgeryStatus unknownNCT04284722Phase 4

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