Indocyanine Green clinical trials
Also written IC-Green.
How each study uses Indocyanine Green is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Indocyanine Green studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Approvals
The first approval found in each region, with its record
- United States
- 9 Feb 1959 · IC-GREEN · NDA 011525 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
105 studies that test it; most in 2013 (12)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2011 | 2 |
| 2012 | 4 |
| 2013 | 12 |
| 2014 | 6 |
| 2015 | 8 |
| 2016 | 9 |
| 2017 | 7 |
| 2019 | 6 |
| 2020 | 7 |
| 2021 | 10 |
| 2022 | 8 |
| 2023 | 4 |
| 2024 | 9 |
| 2025 | 5 |
| 2026 | 7 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 2 · Other 103
Jules Bordet Institute (6) · University of Pennsylvania (5) · Massachusetts General Hospital (4) · Fujian Medical University (3) · University of Rochester (3) · Stanford University (3) · University Health Network, Toronto (2) · St. Jude Children's Research Hospital (2)
Often tested with
Tested in the same studies.
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 10
Studies that test Indocyanine Green.
- Nov 2026Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT SurgeryPhase 2 · Gustave Roussy, Cancer Campus, Grand Paris
- Dec 2026Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Tenosynovial Giant Cell Tumor SurgeryPhase 4 · Shanghai Jiao Tong University Affiliated Sixth People's Hospital
- Dec 2026Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Giant Cell Tumor of Bone SurgeryPhase 4 · Shanghai Jiao Tong University Affiliated Sixth People's Hospital
- Dec 2026Randomized Evaluation of Indocyanine Green Fluorescence Angiography-Guided Versus Standard Clinical Perfusion Assessment During Gluteal Permanent Synthetic Filler RemovalNot applicable · Research Inc
- Jan 2027Bronchial NIR Image-guided ResectionPhase 1/2 · Massachusetts General Hospital
- Jan 2027TumorGlow Intraoperative Molecular Imaging (IMI)Phase 1/2 · University of Pennsylvania
- Mar 2027The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal CholestasisEarly Phase 1 · University of Alabama at Birmingham
- Jun 2027Detection of Upper Gastrointestinal Tumour Depth and Demarcation Using Systemic Administration of Indocyanine Green During Endoscopic Submucosal DissectionPhase 1/2 · University Medical Center Groningen
- Jul 2027The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery.Phase 4 · University Health Network, Toronto
- Sep 2027Near-Infrared Fluorescence Imaging With Indocyanine Green to Evaluate Bowel Anastomoses in Gynecologic Oncology SurgeryPhase 4 · Istanbul University
Studies
Open first, then newest update. How each study uses Indocyanine Green is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 105
- Indocyanine Green With Near Infrared Imaging for Intraoperative Visualization of Head and Neck Squamous Cell CarcinomaRecruitingPhase 2Washington University School of MedicineNCT07825597Written as Indocyanine green
- Indocyanine Green (ICG) Guided Sentinel Lymph Node Mapping for Pediatric Visceral Solid TumorsRecruitingEarly Phase 1St. Jude Children's Research HospitalNCT05645523Written as Indocyanine Green
- Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical Assessment for Flap Perfusion in Head and Neck Reconstruction (VISION Trial)RecruitingPhase 4Region SkaneNCT07635420Written as Indocyanine Green
- Randomized Evaluation of Indocyanine Green Fluorescence Angiography-Guided Versus Standard Clinical Perfusion Assessment During Gluteal Permanent Synthetic Filler RemovalNot yet recruitingNot applicableResearch IncNCT07808957Written as Indocyanine Green
- A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast CancerRecruitingPhase 2University of FloridaNCT06327490Written as Indocyanine green
- Intraoperative Molecular Imaging Using ICG for Head and Neck TumorsRecruitingPhase 2Medical University of South CarolinaNCT07149207Written as Indocyanine Green (ICG)
- Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast CancerRecruitingNot applicableIsabelle HenskensNCT07146295Written as Indocyanine Green
- Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)RecruitingPhase 1University of RochesterNCT05197530Written as Indocyanine green
- Use of Indocyanine Green (ICG) for the Diagnosis of Biliary AtresiaRecruitingPhase 1/2Boston Children's HospitalNCT07513038Written as Indocyanine Green (ICG)
- Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total ThyroidectomyRecruitingPhase 3University Hospital, BrestNCT04785443Written as ICG
- TumorGlow Intraoperative Molecular Imaging (IMI)RecruitingPhase 1/2University of PennsylvaniaNCT04723810Written as Indocyanine Green
- Impact of Intraoperative ICG on Functional Outc in RARPRecruitingEarly Phase 1University of California, IrvineNCT06446648Written as ICG
- The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal CholestasisRecruitingEarly Phase 1University of Alabama at BirminghamNCT07250854Written as Indocyanine Green
- Synapse 3D With Intravascular Indocyanine GreenRecruitingPhase 1/2St. Joseph's Healthcare HamiltonNCT03953144Written as IC-Green (ICG)
- Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Tenosynovial Giant Cell Tumor SurgeryRecruitingPhase 4Shanghai Jiao Tong University Affiliated Sixth People's HospitalNCT07315841Written as Indocyanine Green
- Accuracy of Indocyanine Green (ICG) Fluorescence Imaging in Giant Cell Tumor of Bone SurgeryRecruitingPhase 4Shanghai Jiao Tong University Affiliated Sixth People's HospitalNCT07315828Written as Indocyanine Green
- Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT SurgeryRecruitingPhase 2Gustave Roussy, Cancer Campus, Grand ParisNCT04842162Written as indocyanine green
- Bronchial NIR Image-guided ResectionRecruitingPhase 1/2Massachusetts General HospitalNCT03097575Written as ICG Intervention
- Detection of Upper Gastrointestinal Tumour Depth and Demarcation Using Systemic Administration of Indocyanine Green During Endoscopic Submucosal DissectionRecruitingPhase 1/2University Medical Center GroningenNCT07108855Written as Indocyanine Green (IC-Green)
- Assessing CSF Flow Dynamics in Pediatric Hemorrhagic HydrocephalusRecruitingPhase 1Eva SevickNCT06994949Written as ICG
See all 105 studies that test Indocyanine Green →
Given beside what is tested · 1 — Indocyanine Green is usual care or a partner of the new treatment
As the comparator · 3 — what is tested is compared with Indocyanine Green
- TMTP1-ICG Mapping in Colposcopy-directed BiopsyStatus unknownPhase 1Huazhong University of Science and TechnologyNCT03321461Written as ICG
- TMTP1-ICG Mapping in Laparoscopic SLN Detection in Cervical CancerStatus unknownPhase 1Huazhong University of Science and TechnologyNCT03321448Written as ICG
- TMVP1-ICG Mapping in Laparoscopic SLN Detection in Cervical CancerStatus unknownPhase 1Huazhong University of Science and TechnologyNCT03320772Written as ICG
Codes
What other systems call Indocyanine Green · ClinicalTrials.gg INT007657
- MeSH (NLM) D007208Indocyanine GreenConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) IX6J1063HVINDOCYANINE GREENConfirmed FDA, NLM, Wikidata
- RxNorm 5775Confirmed FDA, Wikidata
- Wikidata Q905662indocyanine greenConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C65913Indocyanine GreenOne source FDA
- DrugBank DB16024One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D007208 | Indocyanine Green | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | IX6J1063HV | INDOCYANINE GREEN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 5775 | — | Confirmed FDA, Wikidata |
| Wikidata | Q905662 | indocyanine green | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C65913 | Indocyanine Green | One source FDA |
| DrugBank | DB16024 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.