DrugBiological
Ifinatamab deruxtecan clinical trials
Also written DS-7300a and MK-2400.
Keep track of what changes. Save the ifinatamab deruxtecan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
14 studies that test it; most in 2025 (6)
| Year | Studies |
|---|---|
| 2019 | 1 |
| 2020 | 1 |
| 2022 | 1 |
| 2024 | 2 |
| 2025 | 6 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 14 · Other 0
Merck Sharp & Dohme LLC (8) · Daiichi Sankyo (5) · Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1)
Often tested with
Tested in the same studies.
Atezolizumab (2) · Gocatamig (2) · Raludotatug deruxtecan (2) · Serotonin 5-HT3 Receptor Antagonists (1) · Neurokinin-1 Receptor Antagonists (1)
Studies
Open first, then newest update. How each study uses ifinatamab deruxtecan is read from its arms, and is right about nine times in ten.
Testing it · 14
- A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT07630974Written as Ifinatamab Deruxtecan
- A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT07227597Written as I-DXd
- A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)RecruitingPhase 3Merck Sharp & Dohme LLCNCT06925737Written as Ifinatamab deruxtecan
- A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT06863272Written as Ifinatamab Deruxtecan
- Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)RecruitingPhase 2Merck Sharp & Dohme LLCNCT06780098Written as I-DXD
- A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT06780137Written as Ifinatamab Deruxtecan (I-DXd)
- A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT07405151Written as I-DXd
- A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)RecruitingPhase 2Merck Sharp & Dohme LLCNCT06780085Written as Ifinatamab Deruxtecan
- A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung CancerRecruitingPhase 3Daiichi SankyoNCT06203210Written as Ifinatamab deruxtecan
- A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)RecruitingPhase 1/2Daiichi SankyoNCT06330064Written as Ifinatamab deruxtecan
- A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)RecruitingPhase 3Daiichi SankyoNCT06644781Written as Ifinatamab deruxtecan
- Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant TumorsActive, not recruitingPhase 1/2Daiichi SankyoNCT04145622Written as Ifinatamab deruxtecan (I-DXd)
- Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)Active, not recruitingPhase 2Daiichi SankyoNCT05280470Written as Ifinatamab Deruxtecan (I-DXd)
- A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)Active, not recruitingPhase 1/2Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT04471727Written as Ifinatamab Deruxtecan (I-DXd)
Given in every arm · 3 — ifinatamab deruxtecan is usual care beside what is tested
- Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT06780111Written as I-DXd
- A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)RecruitingPhase 1/2Daiichi SankyoNCT06362252Written as Ifinatamab deruxtecan
- KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT04165070Written as Ifinatamab Deruxtecan (I-DXd)
Codes
What other systems call ifinatamab deruxtecan · ClinicalTrials.gg INT016190
- UNII (FDA) C6I0GC0GX5IFINATAMAB DERUXTECANOne source FDA
- NCI Thesaurus C171577Ifinatamab DeruxtecanOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | C6I0GC0GX5 | IFINATAMAB DERUXTECAN | One source FDA |
| NCI Thesaurus | C171577 | Ifinatamab Deruxtecan | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.