Glucagon-Like Peptide-1 Receptor Agonists: all 1,407 studies that test it

Page 8 of 15. Open to participants first (306), then studies with results posted, then the rest; newest registration first within each.

• The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes MellitusCompletedNCT00700817Phase 3Results posted
• A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and LiraglutideCompletedNCT00696657Phase 2Results posted
• Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)CompletedNCT00676338Phase 3Results posted
• How Glargine Insulin, Oral Diabetes Medications and Exenatide May Improve Blood Sugar Control and Weight Gain in Type 2 DiabeticsCompletedNCT00667732Phase 4Results posted
• Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 DiabetesCompletedNCT00658021Phase 3Results posted
• Role of Exenatide in NASH-a Pilot StudyCompletedNCT00650546Phase 2/3Results posted
• Efficacy of Exenatide Once Weekly and Once-Daily Insulin Glargine in Patients With Type 2 Diabetes Treated With Metformin Alone or in Combination With Sulfonylurea (DURATION - 3)CompletedNCT00641056Phase 3Results posted
• A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)CompletedNCT00637273Phase 3Results posted
• A Study of Dose Titration of LY2189265 in Overweight Participants With Type 2 Diabetes MellitusCompletedNCT00630825Phase 2Results posted
• Bioenergetic Alterations After Exenatide AdministrationCompletedNCT00623545Phase 4Results posted
• The Effect of Liraglutide on Endothelial Function in Subjects With Type 2 Diabetes MellitusCompletedNCT00620282Phase 3Results posted
• Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 DiabetesCompletedNCT00614120Phase 3Results posted
• Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using a Thiazolidinedione or a Thiazolidinedione and MetforminCompletedNCT00603239Phase 3Results posted
• Efficacy and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Who Are Treated With Oral Antidiabetic(s)CompletedNCT00577824Phase 3Results posted
• The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-DiabetesCompletedNCT00546728Phase 4Results posted
• Effects Of Exenatide On Liver Biochemistry, Liver Histology And Lipid Metabolism In Patients With Fatty Liver DiseaseTerminatedNCT00529204Phase 2Results posted
• Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 DiabetesCompletedNCT00518882Phase 3Results posted
• Out-Patient Study in Patients With Type 2 Diabetes Mellitus Who Are Taking no Diabetes Medication or Metformin OnlyCompletedNCT00518115Phase 2Results posted
• A Study to Assess the Effect of Exenatide Treatment on Mean 24-Hour Heart Rate in Patients With Type 2 DiabetesCompletedNCT00516074Phase 3Results posted
• An Exploratory Study of the Effect of Treatment Interruption on Safety of Exenatide in Patients With Type 2 DiabetesCompletedNCT00516048Phase 3Results posted
• A Pilot Study of Effects of Exenatide on Body Weight in Non-Diabetic, Obese PatientsCompletedNCT00500370Phase 2Results posted
• The Effect of Exenatide on Weight and Hunger in Obese, Healthy WomenCompletedNCT00456885Phase 4Results posted
• Role of Exenatide in Type 1 DiabetesCompletedNCT00456300Phase 2Results posted
• Effect of Exenatide Plus Metformin vs. Insulin Aspart Plus Metformin on Glycemic Control and Hypoglycemia in Patients With Type 2 DiabetesCompletedNCT00434954Phase 3Results posted
• The Effect of Liraglutide on Body Weight in Obese Subjects Without DiabetesCompletedNCT00422058Phase 2Results posted
• Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 DiabetesCompletedNCT00395746Phase 3Results posted
• Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 DiabetesCompletedNCT00393718Phase 3Results posted
• Effect on Weight Loss of Exenatide Versus PlaceboCompletedNCT00375492Phase 3Results posted
• A Study Comparing Exenatide With Basal Insulin in Achieving a Target HbA1c With Minimum Weight Gain in Type 2 Diabetes PatientsCompletedNCT00360334Phase 3Results posted
• Exenatide Versus Glimepiride in Patients With Type 2 DiabetesCompletedNCT00359762Phase 3Results posted
• The Effect of Exenatide Compared to Lantus Insulin on Vascular Function in Type 2 DiabetesCompletedNCT00353834Phase 4Results posted
• To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given TogetherCompletedNCT00318461Phase 3Results posted
• Effects of Exenatide Long-Acting Release on Glucose Control and Safety in Subjects With Type 2 Diabetes Mellitus(DURATION - 1)CompletedNCT00308139Phase 3Results posted
• To Evaluate the Effect of Liraglutide Versus Glimepiride (Amaryl®) on Haemoglobin A1cTerminatedNCT00294723Phase 3Results posted
• An Evaluation of Exenatide and Rosiglitazone in Subjects With Type 2 Diabetes MellitusCompletedNCT00135330Phase 3Results posted
• Effects of Exenatide and Insulin Glargine in Subjects With Type 2 DiabetesCompletedNCT00097500Phase 3Results posted
• Exenatide Compared With Twice-Daily Biphasic Insulin Aspart in Patients With Type 2 Diabetes Using Sulfonylurea and MetforminCompletedNCT00082407Phase 3Results posted
• Effect of AC2993 Compared With Insulin Glargine in Patients With Type 2 Diabetes Also Using Combination Therapy With Sulfonylurea and MetforminCompletedNCT00082381Phase 3Results posted
• ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy AgingCompletedNCT07871799Phase 2
• A Study Comparing the Effects of BGM0504 Injection and Semaglutide Injection on Obese Subjects.CompletedNCT07836140Phase 2
• Weekly GLP-1 Receptor Agonists in Obese Individuals Without DiabetesCompletedNCT07834398Phase 3
• Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical TrialCompletedNCT07820111Phase 3
• Efficacy of Once Weekly Semaglutide in Patients With Type 2 Diabetes: a Non Randomized Clinical TrialCompletedNCT07732218Phase 4
• A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityActive, not recruitingNCT07639021Phase 2
• Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart ValvesCompletedNCT07610174Phase 2
• Use of Liraglutide in Children Aged 6 to 12 Years With Severe ObesityActive, not recruitingNCT07590219Phase 4
• A Study of BGM0504 Tablets in Healthy Chinese SubjectsCompletedNCT07566572Phase 1
• A Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy ParticipantsActive, not recruitingNCT07534592Phase 1
• A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 YearsCompletedNCT07455825Phase 1
• A Study to Investigate the Effect of AZD5004 on Mitiglinide and Pioglitazone in Healthy ParticipantsCompletedNCT07444424Phase 1
• A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or ObesityActive, not recruitingNCT07438444Phase 4
• A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like InjectorCompletedNCT07413913Phase 1
• Bioequivalence Study of BGM0504 InjectionCompletedNCT07382908Phase 1
• Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic SurgeryCompletedNCT07374445Phase 4
• Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent ThalassemiaCompletedNCT07370922Phase 2
• Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor AgonistsActive, not recruitingNCT07325435Phase 4
• A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes MellitusCompletedNCT07313813Phase 1
• Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 DrugsActive, not recruitingNCT07303556Not applicable
• A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes MellitusActive, not recruitingNCT07299084Phase 1
• Effect of GLP-1 on Intestinal Barrier Function in SBS-IF Patients: A Preliminary Exploration.CompletedNCT07297238Not applicable
• A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 DiabetesCompletedNCT07271251Phase 3
• A Study of BGM0504 Tablets in Healthy and Non-diabetic Overweight or Obese Chinese SubjectsCompletedNCT07239973Phase 1
• A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and OsteoarthritisCompletedNCT07225829Phase 2
• Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)Active, not recruitingNCT07223983Phase 1
• A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the BodyCompletedNCT07221591Phase 1
• Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM0504 Tablets in Non-diabetic Overweight or Obese Adult SubjectsCompletedNCT07166081Phase 1
• A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the KneeActive, not recruitingNCT07153471Phase 3
• The Long COVID Treatment TrialActive, not recruitingNCT07128082Phase 2
• A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 DiabetesActive, not recruitingNCT07087795Phase 1
• A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up in the BodyCompletedNCT07071974Phase 1
• A Study of BGM0504 in Participants With Type 2 Diabetes in IndonesiaActive, not recruitingNCT07064486Phase 3
• A Study in Healthy Participants to Investigate Relative Bioavailability of AZD5004 in Three Solid Oral FormulationsCompletedNCT06996886Phase 1
• A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 DiabetesActive, not recruitingNCT06993792Phase 3
• A Phase Ib Study of AZD5004 in Chinese Participants With Overweight/Obesity With or Without Type 2 Diabetes MellitusCompletedNCT06988553Phase 1
• A Study of BGM0504 in Chinese Patients With Type 2 DiabetesCompletedNCT06974825Phase 2
• A Study of BGM0504 Evaluating Weight Loss in Overweight or Obese Chinese SubjectsCompletedNCT06973681Phase 2
• A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 DiabetesActive, not recruitingNCT06972472Phase 3
• A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related ComorbidityActive, not recruitingNCT06972459Phase 3
• A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related ComorbidityActive, not recruitingNCT06965413Phase 2
• A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or OverweightActive, not recruitingNCT06962280Phase 3
• A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2Active, not recruitingNCT06952530Phase 3
• A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy ParticipantsCompletedNCT06948747Phase 1
• A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1Active, not recruitingNCT06948435Phase 3
• A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)Active, not recruitingNCT06948422Phase 3
• Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIVCompletedNCT06935838Phase 2
• A Study of BGM0504 in Healthy Participants and Participants With Impaired Renal FunctionCompletedNCT06929156Phase 1
• A Study of BGM0504 in Overweight or Obese ParticipantsCompletedNCT06920056Phase 1
• Efficacy and Safety of Tirzepatide for Weight ManagementActive, not recruitingNCT06918405Phase 3
• A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or ObesityCompletedNCT06916065Phase 1
• A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or OverweightActive, not recruitingNCT06914895Phase 3
• A Study of BGM0504 in Participants With ObesityCompletedNCT06911203Phase 2
• Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen Deprivation TherapyActive, not recruitingNCT06908694Phase 4
• A Study of Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Participants With Obesity or Overweight With Type 2 DiabetesWithdrawnNCT06901349Phase 2
• Semaglutide in Women With Polycystic Ovary Syndrome and ObesityCompletedNCT06896981Phase 2/3
• Effect of Tirzepatide on Brown Adipose Tissue in ObesityCompletedNCT06893211Phase 2
• A Study of Bimagrumab Alone (LY3985863) and Bimagrumab With Tirzepatide (LY900042) in Healthy ParticipantsCompletedNCT06890611Phase 1
• A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)Active, not recruitingNCT06864026Phase 4
• GLP-1s to Enhance Lasting Optimal WeightActive, not recruitingNCT06861439Phase 4
• A Study to Assess the Mass Balance and ADME of [14C]AZD5004 and the Absolute Bioavailability of AZD5004CompletedNCT06857695Phase 1
• Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)Active, not recruitingNCT06854614Phase 4

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