Glucagon-Like Peptide-1 Receptor Agonists: all 1,407 studies that test it

Page 9 of 15. Open to participants first (306), then studies with results posted, then the rest; newest registration first within each.

• Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.CompletedNCT06851962Phase 4
• A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or OverweightCompletedNCT06824051Phase 1
• Investigation of the Relationship Between Peripheral and Central Metabolic Changes Induced by GLP-1 AgonistsCompletedNCT06818292Not applicable
• A Study of a Novel Precision Medicine Approach For ObesityActive, not recruitingNCT06814938Phase 4
• Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004CompletedNCT06813781Phase 1
• Optimization of Obesity for Total Knee Replacement With Glucagon-like Peptide-1 Receptor AgonistActive, not recruitingNCT06807970Early Phase 1
• Bariatric Surgery vs. Semaglutide vs. TirzepatideActive, not recruitingNCT06803888Phase 4
• Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor FunctionsActive, not recruitingNCT06801015Phase 4
• A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityActive, not recruitingNCT06780449Phase 3
• A Study in Healthy People to Compare How 3 Different Formulations of Survodutide Are Taken up in the BodyCompletedNCT06772532Phase 1
• Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 DiabetesCompletedNCT06762314Phase 2
• A Study of a Weight Loss Intervention in People With Endometrial CancerActive, not recruitingNCT06751589Early Phase 1
• A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With ObesityActive, not recruitingNCT06745284Phase 1
• Tirzepatide for Obesity and Meth Use DisorderCompletedNCT06745128Phase 2
• A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004CompletedNCT06742762Phase 1
• Randomized Control Trial of Sleeve Gastrectomy With Tirzepatide in Maximizing Weight LossActive, not recruitingNCT06734273Early Phase 1
• Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM0504 Injection in Non-diabetic Overweight or Obese Adult SubjectsCompletedNCT06714955Phase 1
• A Study of BGM0504 Injection in Participants With Obesity or OverweightCompletedNCT06704581Phase 3
• A Study to Investigate Multiple Ascending Doses of AZD5004 in Healthy Japanese Participants and Participants With Type 2 Diabetes MellitusCompletedNCT06703658Phase 1
• A Study of Enlicitide Decanoate (MK-0616) and Semaglutide in Healthy Adult Participants (MK-0616-023)CompletedNCT06699329Phase 1
• A Study of Orforglipron (LY3502970) to Compare a Single Capsule and Multiple Capsules in Healthy ParticipantsCompletedNCT06692348Phase 1
• Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIVActive, not recruitingNCT06691243Phase 2
• Strict Weight Management Based on GLP-1 RA for Ablation Outcomes in Overweight or Obese Patients with T2DM and AFCompletedNCT06660134Not applicable
• A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or OverweightCompletedNCT06649045Phase 3
• A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or OverweightActive, not recruitingNCT06643728Phase 2
• A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During RamadanCompletedNCT06635057Phase 4
• Semaglutide and Intestinal Iron AbsorptionCompletedNCT06629688Not applicable
• The Effect of Combined Dulaglutide and Dapagliflozin Treatment vs DPP-4 Inhibitors in Endothelial and Vascular Function in Patients With Type 2 Diabetes Mellitus and AlbuminuriaActive, not recruitingNCT06611904Not applicable
• Glucagon-like Peptide-1 Receptor Agnoists for the Assessment of Adrenal FunctionCompletedNCT06608433Not applicable
• A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 DiabetesCompletedNCT06603571Phase 2
• Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or OverweightCompletedNCT06588296Phase 3
• Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or OverweightCompletedNCT06588283Phase 3
• A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)CompletedNCT06584916Phase 3
• Efficacy, Safety, and Tolerability of Once Daily Oral Administration of AZD5004 Versus Placebo for 26 Weeks in Adults With Type 2 Diabetes Mellitus.CompletedNCT06579105Phase 2
• Effects of AZD5004 in Adults Who Are Living With Obesity or Overweight With at Least 1 Weight-related ComorbidityCompletedNCT06579092Phase 2
• Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs PlaceboActive, not recruitingNCT06577090Phase 2
• STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossActive, not recruitingNCT06571383Phase 4
• A Study to Test Whether BI 456906 (Survodutide) Influences the Amount of Bupropion, Caffeine and Midazolam in the Blood in People With Overweight or ObesityCompletedNCT06564441Phase 1
• Effect of Oral Semaglutide on Epicardial and Pericoronary Adipose Tissues in Type 2 Diabetes After Myocardial InfarctionStatus unknownNCT06557811Phase 4
• A Study to Investigate Multiple Ascending Doses and Relative Bioavailability of AZD5004 in Healthy ParticipantsCompletedNCT06555822Phase 1
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothCompletedNCT06534411Phase 3
• Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and OverTerminatedNCT06515418Phase 2
• Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®.CompletedNCT06497049Phase 1
• A Study in Chinese People With Overweight or Obesity to Test How Different Doses of Survodutide Are Taken up in the BodyCompletedNCT06492135Phase 1
• The Effects of Semaglutide vs Testosterone Replacement Therapy on Functional Hypogonadism and Sperm Quality in Men With Type 2 Diabetes Mellitus and ObesityCompletedNCT06489457Phase 3
• Effect of Semaglutide on the Psoriatic Lesions in Patients With Type 2 Diabetes MellitusCompletedNCT06475586Phase 4
• The Effects of Semaglutide on Body Composition and Performance in Military PersonnelWithdrawnNCT06468748Phase 4
• Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver DiseaseCompletedNCT06409130Phase 2
• Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesCompletedNCT06403761Phase 1
• The Effect of Weekly Semaglutide Treatment on Energy ExpenditureCompletedNCT06390501Not applicable
• A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose WeightCompletedNCT06388187Phase 3
• Semaglutide and Cognition in Healthy VolunteersCompletedNCT06363487Not applicable
• A Study in People With Overweight or Obesity to Test How BI 1820237, BI 456906, or a Combination of Both Affects Brain ActivityCompletedNCT06352424Phase 1
• A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney ProblemsCompletedNCT06352411Phase 1
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and ExerciseCompletedNCT06323174Phase 3
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminCompletedNCT06323161Phase 3
• A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight (SYNCHRONIZE-MASLD)CompletedNCT06309992Phase 3
• A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass PreservationActive, not recruitingNCT06299098Phase 2
• A Study of LY3841136 in Japanese Participants With Obesity or OverweightCompletedNCT06297616Phase 1
• ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy ParticipantsCompletedNCT06293742Phase 1
• A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)CompletedNCT06269107Phase 3
• ECC5004 RBA FE Study in Healthy ParticipantsCompletedNCT06268145Phase 1
• A Study of How CagriSema Works on Appetite in People With Excess Body WeightCompletedNCT06267092Phase 1
• Exenatide For Reducing the Reinforcing Effects of CocaineWithdrawnNCT06252623Phase 1
• A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes MellitusCompletedNCT06235086Phase 3
• Semaglutide and Polycystic Ovarian Syndrome: an Emerging Treatment StrategyWithdrawnNCT06222437Phase 1
• A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorCompletedNCT06221969Phase 3
• A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose WeightCompletedNCT06214741Phase 3
• A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightCompletedNCT06207877Phase 1
• Liraglutide Effectiveness in Preoperative Weight-loss for Bariatric-metabolic SurgeryCompletedNCT06201819Phase 4
• A Study to Test Whether Multiple Doses of BI 456906 Have an Effect on Cardiac Safety in People With Overweight or ObesityCompletedNCT06200467Phase 1
• Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA)Active, not recruitingNCT06191848Phase 4
• DUTCH Weight Control in Atrial Fibrillation StudyActive, not recruitingNCT06184633Phase 4
• Renoprotective Effects of Dulaglutide in Patients With Type 2 Diabetic NephropathyCompletedNCT06182891Not applicable
• A Study to Test Whether Survodutide Helps Japanese People Living With Obesity DiseaseCompletedNCT06176365Phase 3
• Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory IssuesSuspendedNCT06171152Early Phase 1
• GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot TrialActive, not recruitingNCT06162715Phase 2/3
• Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes MellitusCompletedNCT06161844Phase 3
• A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightCompletedNCT06131437Phase 3
• A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and PlaceboCompletedNCT06131372Phase 2
• A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation IIICompletedNCT06097390Phase 1
• Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 DiabetesWithdrawnNCT06083675Phase 3
• A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)CompletedNCT06077864Phase 3
• A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related ComorbiditiesActive, not recruitingNCT06075667Phase 3
• A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose WeightCompletedNCT06066528Phase 3
• A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose WeightCompletedNCT06066515Phase 3
• A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorCompletedNCT06065540Phase 3
• The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical TrialActive, not recruitingNCT06050577Phase 2
• A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related ComorbiditiesCompletedNCT06047548Phase 3
• DIALYSIS-TIR StudyActive, not recruitingNCT06042153Phase 4
• A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and ObesityActive, not recruitingNCT06037252Phase 2
• The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial PressureCompletedNCT06027567Phase 4
• Semaglutide Therapy for Alcohol Reduction (STAR)Active, not recruitingNCT06015893Phase 2
• Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With ObesityWithdrawnNCT06009653Phase 4
• Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DMActive, not recruitingNCT06005012Phase 2
• A Research Study Comparing the Effect of Different Dosing Conditions on Blood Levels of Semaglutide in a New Tablet Composition in Healthy ParticipantsCompletedNCT05996874Phase 1
• A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose WeightCompletedNCT05996848Phase 3
• Effect of Liraglutide in Obese Women With Polycystic Ovary SyndromeCompletedNCT05965908Phase 3
• Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke Treated by Reperfusion TherapiesCompletedNCT05920889Phase 2
• A Study in Women With Overweight or Obesity to Test Whether Different Doses of BI 456906 Influence the Amount of a Contraceptive in the BloodCompletedNCT05896384Phase 1

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