Fluorouracil: all 820 studies that test it

Page 1 of 9. Open to participants first (101), then studies with results posted, then the rest; newest registration first within each.

• Testing Safe Doses of Anti-Cancer Medicines, 5-Flurouracil (5-FU) and Tretinoin (ATRA), Added to the Usual Cancer Treatment of EpendymomaNot yet recruitingNCT07848568Phase 1/2
• Sintilimab Plus NALIRIFOX or Gemcitabine-Cisplatin as First-Line Treatment for Metastatic Biliary Tract CancerRecruitingNCT07831993Phase 2
• Liposomal Irinotecan Plus 5-FU/LV and Sintilimab With Sequential SBRT for Locally Advanced Biliary Tract CancerRecruitingNCT07797816Phase 2
• A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With Advanced Solid Tumors (MK-2010-002)Not yet recruitingNCT07793942Phase 2
• A Prospective, Open-Label, Randomized Controlled Clinical Study Comparing Hepatic Arterial Infusion Chemotherapy (HAIC) With Capecitabine as Adjuvant Therapy After Radical Surgery for Malignant Biliary Tract TumorsRecruitingNCT07790445Phase 4
• SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC TrialNot yet recruitingNCT07748611Phase 2
• DCE-MRI for Neoadjuvant Treatment Assessment in Patients With Borderline Resectable Pancreatic CancerRecruitingNCT07705919Phase 1/2
• Phase Ib/IIa Open-label Study, to Evaluate Safety, Tolerability, and Antitumor Activity of HCB101 in Combination With Multiple Agents in Subjects With Advanced Gastric or Gastro-esophageal (GEJ) AdenocarcinomaNot yet recruitingNCT07680569Phase 1/2
• A Clinical Study of SHR-A1811 in Combination With Chemotherapy and Bevacizumab Versus Standard Therapy as First-Line Treatment for Advanced Colorectal CancerRecruitingNCT07676162Phase 3
• Carbon Dioxide Laser-Assisted Delivery of Triamcinolone With or Without 5-Fluorouracil for Hypertrophic Burn ScarsNot yet recruitingNCT07660120Not applicable
• A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02)RecruitingNCT07554456Phase 2/3
• Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine TherapyRecruitingNCT07456852Phase 1/2
• 5-Fluorouracil Response and Optimization STudy (The FROST Trial)RecruitingNCT07419464Phase 2
• A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib StudiesRecruitingNCT07415031Phase 2
• Actinic Keratoses Treated With 5-fluorouracil Plus AluminumRecruitingNCT07401277Phase 1
• Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal CancerNot yet recruitingNCT07363408Phase 1
• Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingNCT07352566Phase 4
• NH002-mediated Sonoporation With Chemotherapy in Advanced Pancreatic CancerNot yet recruitingNCT07314385Phase 1
• A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.RecruitingNCT07283367Phase 1/2
• A Study of YL242 in Subjects With Advanced Solid TumorsRecruitingNCT07197827Phase 1/2
• Hypofractionated Radiotherapy Combined With NALIRIF, PD-1 Antibody in Locally Recurrent Rectal Cancer(NOVELTY-R)RecruitingNCT07183865Phase 2
• DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-AdjustmentRecruitingNCT07158164Phase 4
• Efficacy Evaluation of 5-Fluorouracil as an Adjuvant to Endoscopic Dacryocystorhinostomy in Managing Primary Acquired Nasolacrimal Duct Obstruction With Small Lacrimal Sac: A Randomized Controlled StudyRecruitingNCT07154121Not applicable
• Irinotecan Liposome II + 5-FU/LV + Oxaliplatin + Karelizumab in Neoadjuvant Treatment of Gastric CancerNot yet recruitingNCT07085273Phase 2
• Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic AdenocarcinomaRecruitingNCT07076212Phase 2
• A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal AdenocarcinomaRecruitingNCT07069712Phase 2
• mFOLFOX/mFOLFIRI vs. mFOLFOX in Advanced or Recurrent Biliary Tract Cancer Second-lineRecruitingNCT07062536Phase 2
• Microneedling Alone Versus Microneedling Coupled With Either Bleomycin or 5flourouracil in the Treatment of Plantar WartsNot yet recruitingNCT07041749Not applicable
• PANORAMIX : Optimizing 1st-line NALIRIFOX and Exploring Microbiota's Role in 2nd Line Pancreatic Cancer TreatmentNot yet recruitingNCT07028424Phase 2
• A Irinotecan Liposome Trial of in Advanced Neuroendocrine CarcinomaNot yet recruitingNCT07014540Phase 4
• Preoperative Chemoradiotherapy Combined With Consolidation or Induction NALIRIFOX in Rectal Cancer.RecruitingNCT06894797Not applicable
• Personalized Tumor Neoantigen MRNA Therapy for Advanced Pancreatic Cancer.Not yet recruitingNCT06888648Phase 1/2
• A Pilot Clinical Trial Comparing Topical Fluorouracil to Fluorouracil Plus Calcipotriene Field Treatments in Patients With Multiple Actinic KeratosesRecruitingNCT06851507Phase 3
• NALIRIFOX Before Surgery for the Treatment of Borderline Resectable Pancreatic Ductal Adenocarcinoma, Nectar TrialRecruitingNCT06821997Phase 2
• DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic CancerRecruitingNCT06757244Phase 2
• Hepatic Arterial Infusion Chemotherapy and Immunotherapy for Hepatocellular CarcinomaRecruitingNCT06741020Phase 1/2
• Efficacy of Organoid-Based Chemotherapy Drug Precision Screening to Guide Treatment for Thyroid CancerNot yet recruitingNCT06713057Phase 2
• Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGSNot yet recruitingNCT06692491Phase 2
• Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic KeratosesNot yet recruitingNCT06685588Not applicable
• Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal CancerRecruitingNCT06654037Phase 1
• CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRCNot yet recruitingNCT06652412Phase 2
• Adebelimab Combined With Irinotecan Liposomal Injection, Oxaliplatin, Fluorouracil and Calcium Folinate Are Used in the First-line Treatment of Pancreatic Cancer Liver Metastasis Efficacy and SafetyRecruitingNCT06531278Phase 2
• A Randomized, Double-blinded, Self-controlled Clinical Study of Intralesional Injection of 5-fluorouracil Plus Triamcinolone for the Treatment of Refractory Nodular PrurigoNot yet recruitingNCT06524323Phase 3
• A Phase 2 Study of SSGJ-707 in Metastatic Colorectal Cancer PatientsRecruitingNCT06493760Phase 2
• Chemotherapy Plus EGFR Monoclonal Antibody in Patients With Liver Metastases From Colorectal Cancer With ctDNA Superselective Negative GenesNot yet recruitingNCT06490913Phase 2
• The Sagittarius TrialRecruitingNCT06490536Phase 3
• Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic KeratosisEnrolling by invitationNCT06461442Phase 4
• Newly Emerging Immunotherapy for Pancreatic Cancer TreatmentNot yet recruitingNCT06370754Phase 1/2
• NALIRIFOX in Combination With Camrelizumab for BRPC: a Prospective, Exploratory StudyRecruitingNCT06345300Phase 2
• Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal CancerRecruitingNCT06341296Phase 2
• Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology CombinationsRecruitingNCT06279130Phase 2/3
• Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal CancerRecruitingNCT06225622Phase 1
• HR070803 in Combination With Oxaliplatin, 5-fluorouracil/LV Versus GX as Adjuvant Therapy for Pancreatic CancerNot yet recruitingNCT06217042Phase 3
• Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOXNot yet recruitingNCT06210360Phase 2
• Perioperative Adebrelimab and Chemotherapy in Esophageal and Esophagogastric Junction CarcinomaNot yet recruitingNCT06198465Phase 2
• Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal CancerRecruitingNCT06184698Phase 2
• The Efficacy and Safety of Using Intralesional 5-fluorouracil for Basal Cell CarcinomaRecruitingNCT06150144Phase 3
• Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction AdenocarcinomaRecruitingNCT06078709Phase 2
• Nivolumab in Children and Adults With Nasopharyngeal CarcinomaRecruitingNCT06019130Phase 2
• Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric CancerRecruitingNCT05982301Phase 2
• Adaptive Radiation in Anal CancerRecruitingNCT05838391Not applicable
• Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled TrialRecruitingNCT05766605Phase 3
• Tislelizumab Combined APF Chemotherapy in the Treatment of Locally Advanced Head and Neck TumorsRecruitingNCT05758389Phase 2
• HR070803 in Combination With Oxaliplatin, 5-FU/LV Versus AG for First-line Treatment of Advanced Pancreatic CancerRecruitingNCT05751850Phase 3
• Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)RecruitingNCT05733689Phase 1
• Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaRecruitingNCT05702229Phase 2
• Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled TrialRecruitingNCT05701436Phase 3
• Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening TrialRecruitingNCT05564377Phase 2
• A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat CancerRecruitingNCT05491512Phase 2
• Pembrolizumab in Combination With Low-dose PFas Neoadjuvant Treatment for Locally Advanced HNSCCRecruitingNCT05446467Phase 2
• GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant AscitesRecruitingNCT05438459Phase 1/2
• SMART TNT for the Conservative Management of Locally Advanced Rectal CancerRecruitingNCT05412082Phase 1
• ATATcH Alternating Treatment Plans for Advanced CancerRecruitingNCT05358548Phase 2
• Phase I/II Study of the Combination of Irinotecan and POF (POFI) and TislelizumabRecruitingNCT05319639Phase 1/2
• Perioperative FLOT vs Adjuvant XELOX for CA StomachRecruitingNCT05264896Phase 3
• A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCCRecruitingNCT05221658Phase 2
• Induction Chemotherapy and Tazemetostat for Locally Advanced SMARCB1-deficient Sinonasal CarcinomaNot yet recruitingNCT05151588Phase 2
• Recombinant Human Adenovirus Type 5 Plus HAIC of FOLFOX for Intrahepatic CholangiocarcinomaRecruitingNCT05124002Phase 4
• ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver MetastasesRecruitingNCT05062317Phase 2
• HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICCRecruitingNCT04961970Phase 3
• An Open-label, Multicentre, Phase II/III RCT of PFLL Versus GP Combined With JS001 as the First-line Therapy for mNPCNot yet recruitingNCT04890522Phase 2/3
• Efficacy of Hyperthermic Intraperitoneal ChemotherapyRecruitingNCT04861558Phase 3
• Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 1
• Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel ObstructionRecruitingNCT04840264Phase 2
• Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal CancerRecruitingNCT04703101Phase 1
• 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.RecruitingNCT04689347Phase 1/2
• PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration SamplesRecruitingNCT04683315Phase 2
• NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal CancerRecruitingNCT04615013Phase 1
• Induction Chemotherapy in Locally Advanced Hypopharyngeal Carcinoma: a Randomised Phase 3 TrialRecruitingNCT04502641Phase 3
• Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal CancerRecruitingNCT04460352Phase 3
• An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal CancerNot yet recruitingNCT04443543Phase 2
• Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar CancerRecruitingNCT04380545Phase 1/2
• PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingNCT04329494Phase 1
• Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel CancersRecruitingNCT04205968Phase 2
• Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic CancerRecruitingNCT03977233Phase 2
• Pan Tumor Rollover StudyRecruitingNCT03899155Phase 2
• Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCCRecruitingNCT03370406Phase 1
• Phage II Trial of Stathmin as Predictive Biomarker for TPF Induction Chemotherapy in OSCCRecruitingNCT03326947Phase 2
• A Randomized Trial of Chemotherapy in Surgical Patients With Infiltrating Ductal Carcinoma of BreastRecruitingNCT02897700Phase 1
• Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the LiverRecruitingNCT02885753Phase 3

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