Estradiol: all 307 studies that test it

Page 1 of 4. Open to participants first (32), then studies with results posted, then the rest; newest registration first within each.

• Post-traumatic Estradiol Administration and Care Evaluation (PEACE)Not yet recruitingNCT07868536Phase 2
• Cyclic vs. Constant Estradiol: Regimens' Effects on Brain HealthRecruitingNCT07831499Phase 4
• Pre-pubertal Low Dose Transdermal Estradiol in Turner SyndromeNot yet recruitingNCT07784582Phase 2
• Acute Effects of Estradiol Administration on Brain Function During Fear LearningNot yet recruitingNCT07737613Early Phase 1
• Hormone thERapy Effects on BRAin-HEART Health During the Menopausal TransitionNot yet recruitingNCT07732452Phase 4
• Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal WomenRecruitingNCT07617454Not applicable
• VEDA Study (DHEA vs Estradiol)RecruitingNCT07574216Not applicable
• Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNCT07568574Not applicable
• Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIVNot yet recruitingNCT07526948Phase 4
• Estradiol and Intrusive MemoriesRecruitingNCT07419594Not applicable
• Plasma Oxytocin Response to Oral Estrogens in Healthy Controls and AVP-DeficiencyRecruitingNCT07361263Not applicable
• COMPASS - COpenhagen MenoPAuSe StudyRecruitingNCT07254429Phase 2
• Vaginal Estrogen Treatment and Effect on Hemostatic Parameters in Postmenopausal WomenRecruitingNCT07160504Phase 4
• A Study Comparing Different Treatment Approaches for the Initiation of Puberty in Girls With Turner Syndrome Using a TRIFECTA-DARED Approach for Rare DiseasesNot yet recruitingNCT07041814Phase 2
• Impact of the Presence of the Corpus Luteum on Pregnancies Obtained Through Frozen Embryo Transfer(FET)RecruitingNCT06896617Phase 4
• Menopausal HT for Women Living With HIV (HoT)RecruitingNCT06856174Phase 4
• Role of Menopause in ThermoregulationRecruitingNCT06798571Phase 4
• Convergent Mechanisms Underlying Reprometabolic Syndrome in WomenRecruitingNCT06686537Phase 2
• Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of DepressionRecruitingNCT06610305Phase 4
• Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner SyndromeRecruitingNCT06570460Phase 4
• Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced AbortionRecruitingNCT06546397Phase 1
• Determining Dose Equivalence Between Oral and Transdermal Estrogen Treatment in Women With Turner SyndromeRecruitingNCT06544473Phase 4
• Estrogen Deficiency on Cardiovascular RiskNot yet recruitingNCT06369363Early Phase 1
• Cardiometabolic Consequences of the Loss of Ovarian FunctionRecruitingNCT06264882Phase 4
• Endometrial Preparation in Frozen Embryo Transfer CyclesRecruitingNCT06181305Phase 4
• Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA UsersRecruitingNCT06067217Not applicable
• STUDY02001740;22SCH740: Estradiol For ER+ Advanced Breast Cancer (ESTHER)RecruitingNCT05716516Phase 2
• Postpartum Vaginal Estrogen for Breastfeeding PatientsRecruitingNCT05457972Phase 4
• Examining the Effects of Estradiol on Neural and Molecular Response to RewardRecruitingNCT05282277Phase 4
• Sex Differences in Myocardial Steatosis Induced Left Ventricular DysfunctionRecruitingNCT04671966Phase 4
• Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary SyndromeRecruitingNCT03401047Early Phase 1
• HRT Versus MOS for Endometrial Preparation Prior to FET in Non PCOS PatientsRecruitingNCT02330757Phase 4
• Brain Blood Flow Responses to Stress: Sex DifferencesCompletedNCT06253702Phase 4Results posted
• Estradiol Therapy In Transgender Women to Research Interactions With HIV TherapyTerminatedNCT06005610Phase 2Results posted
• Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspareunia in Women With Vulvur and Vaginal AtrophyCompletedNCT05617820Phase 3Results posted
• Preventing Recurrent UTI With Vaginal EstrogenCompletedNCT05551949Phase 4Results posted
• Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral ContraceptiveTerminatedNCT05264506Phase 3Results posted
• Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGWCompletedNCT04760691Phase 1Results posted
• Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender WomenCompletedNCT04283656Phase 1Results posted
• Neurobiology of Bulimia NervosaCompletedNCT04225221Phase 2Results posted
• Estrogen and Fear in PTSDCompletedNCT04192266Phase 3Results posted
• Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental ApproachCompletedNCT04112368Phase 4Results posted
• Accelerated Genital Tract Aging in HIV: Estradiol Clinical TrialCompletedNCT04079218Phase 4Results posted
• Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine ModelCompletedNCT04051320Phase 2Results posted
• Transgender EstradiolCompletedNCT04036500Early Phase 1Results posted
• Neuroendocrine Risk for PTSD in WomenCompletedNCT03973229Early Phase 1Results posted
• Postmenopausal Pessary Users: Estrogen Versus TrimosanTerminatedNCT03943823Phase 4Results posted
• Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast CancerActive, not recruitingNCT03941730Phase 2Results posted
• Oophorectomy, Estrogen Therapy and Cardiovascular Disease Risk in Young WomenCompletedNCT03815929Phase 2Results posted
• Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine FibroidsCompletedNCT03751124Phase 3Results posted
• Effect of Perimenstrual Ovarian Steroid Supplementation on Perimenstrual SuicidalityCompletedNCT03720847Phase 4Results posted
• The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal WomenCompletedNCT03681691Phase 1Results posted
• SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated PainCompletedNCT03654274Phase 3Results posted
• Unique Effects of Perimenstrual Estradiol or Progesterone Supplementation on Perimenstrual SuicidalityCompletedNCT03498313Phase 4Results posted
• Vaginal Estrogen on Postpartum Atrophy, Perineal Pain, and Sexual FunctionCompletedNCT03493126Phase 4Results posted
• LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine FibroidsCompletedNCT03412890Phase 3Results posted
• Study to Evaluate the Equivalence of Estradiol Vaginal Cream to Reference Standard in the Treatment of Vaginal AtrophyCompletedNCT03332303Phase 3Results posted
• Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal WomenCompletedNCT03271489Phase 3Results posted
• Treating Postmenopausal Dyspareunia Where it HurtsCompletedNCT03240081Phase 4Results posted
• A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Participants With Moderate to Severe Endometriosis-Associated PainCompletedNCT03213457Phase 3Results posted
• LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine FibroidsCompletedNCT03103087Phase 3Results posted
• LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine FibroidsCompletedNCT03049735Phase 3Results posted
• Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young WomenCompletedNCT03018366Phase 2Results posted
• The Menopause Transition: Estrogen Variability, Stress Reactivity and MoodTerminatedNCT03003949Phase 4Results posted
• A Study Comparing Estradiol Vaginal Cream to Estrace® Cream in Females With Atrophic VaginitisCompletedNCT02995694Phase 3Results posted
• Comparative Safety and Efficacy of Two Treatments in the Treatment of Vulvar and Vaginal AtrophyCompletedNCT02770365Phase 3Results posted
• Estrogen Diastolic Heart FailureTerminatedNCT02693002Phase 4Results posted
• Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study)CompletedNCT02691494Phase 3Results posted
• Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal WomenCompletedNCT02654054Phase 3Results posted
• KEEPS Mammographic Density And Breast Health Ancillary StudyCompletedNCT02524561Not applicableResults posted
• The Vaginal Health TrialCompletedNCT02516202Phase 3Results posted
• Investigation of Female Reproductive Hormone Dynamics During AdolescenceCompletedNCT02486757Early Phase 1Results posted
• Transdermal Estrogen in Older Premenopausal Women With Anorexia NervosaCompletedNCT02475265Phase 2Results posted
• Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission TomographyCompletedNCT02455453Phase 2Results posted
• TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal AtrophyCompletedNCT02449902Phase 2Results posted
• Synthetic vs Natural Estrogen in Combined Oral ContraceptionCompletedNCT02352090Phase 4Results posted
• Perimenopausal Effects of Estradiol on Reward ResponsivenessCompletedNCT02255175Phase 4Results posted
• Estradiol Vaginal Softgel Capsules in Treating Symptoms of Vulvar and Vaginal Atrophy in Postmenopausal WomenCompletedNCT02253173Phase 3Results posted
• Effect of Oral Estradiol and Progesterone Therapy on Vaginal Cytokines in Postmenopausal WomenCompletedNCT02224313Phase 3Results posted
• Treatment of Prepubertal Labial AdhesionsCompletedNCT02218463Not applicableResults posted
• ER Reactivation Therapy for Breast CancerCompletedNCT02188745Phase 2Results posted
• Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in WomenCompletedNCT02122198Not applicableResults posted
• A Safety and Efficacy Study of the Combination Estradiol and Progesterone to Treat Vasomotor SymptomsCompletedNCT01942668Phase 3Results posted
• The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone MassTerminatedNCT01928082Phase 2Results posted
• Estradiol Levels in Patients Treated With EstringCompletedNCT01923298Phase 2Results posted
• Study to Evaluate Safety and Efficacy of WC3011 (Estradiol Vaginal Cream) in Postmenopausal Women With DyspareuniaCompletedNCT01845649Phase 3Results posted
• Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and ParturitionCompletedNCT01762943Not applicableResults posted
• A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)CompletedNCT01709318Phase 2Results posted
• Study of the Contraceptive Efficacy and Safety of a NOMAC-E2 Combined Oral Contraceptive (COC)(P06448)TerminatedNCT01656434Phase 3Results posted
• Hormone Replacement and Neural Cardiovascular Control in Postmenopausal WomenTerminatedNCT01633814Not applicableResults posted
• Mirena and Estrogen for Control of Perimenopause Symptoms and Ovulation SuppressionCompletedNCT01613131Not applicableResults posted
• Timing Estrogen After MenoPaUSeCompletedNCT01605071Not applicableResults posted
• Relationship Between the Menstrual Cycle and Heart Disease in WomenCompletedNCT01546454Not applicableResults posted
• Evaluate Long-Term Safety and Efficacy WC3011 (Estradiol Vaginal Cream)CompletedNCT01455597Phase 3Results posted
• Assessment of Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone InhibitionTerminatedNCT01428245Not applicableResults posted
• Effects of Androgen Blockade on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and ProgesteroneTerminatedNCT01428193Not applicableResults posted
• Safety & Efficacy WC3011 (Estradiol Vaginal Cream) in the Treatment of Vulvovaginal Atrophy in Postmenopausal WomenCompletedNCT01400776Phase 3Results posted
• Estrogen Sensitivity and Ovulatory Dysfunction in ObesityCompletedNCT01381016Not applicableResults posted
• Bioequivalence of Nomegestrol Acetate (NOMAC) and Estradiol (E2) in Commercial Versus Phase 3 Pivotal Clinical Batches of NOMAC-E2 Tablets (P06328)CompletedNCT01345786Phase 1Results posted
• Perimenopausal Estrogen Replacement Therapy StudyCompletedNCT01308814Phase 2/3Results posted

← Estradiol overview