Cytochrome P-450 CYP3A Inhibitors: all 906 studies that test it

Page 3 of 10. Open to participants first (60), then studies with results posted, then the rest; newest registration first within each.

• Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé)CompletedNCT00928187Phase 3Results posted
• A Safety Study to Evaluate the Antiviral Activity of Darunavir in Combination With Ritonavir in HIV 1 Infected ChildrenCompletedNCT00919854Phase 2Results posted
• A Study to Evaluate Antiviral Activity of Darunavir + Ritonavir in HIV-1 Infected AdolescentsCompletedNCT00915655Phase 2Results posted
• Beta Glucan Assay in Patients Receiving Voriconazole ProphylaxisCompletedNCT00904995Phase 3Results posted
• Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC)CompletedNCT00895453Not applicableResults posted
• Use of Low Dose Ketoconazole in Prostate Cancer That Does Not Respond to Hormone Therapy and Prior ChemotherapyCompletedNCT00895310Phase 2Results posted
• Safety and Efficacy of Cobicistat-boosted Atazanavir Compared to Ritonavir-boosted Atazanavir in Combination With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive AdultsCompletedNCT00892437Phase 2Results posted
• A Two-dose Level Clinical Trial of Itraconazole in Patients With Metastatic Prostate Cancer Who Have Had Disease Progression While on Hormonal TherapyCompletedNCT00887458Phase 2Results posted
• Atazanavir and Lamivudine for Treatment SimplificationCompletedNCT00885482Phase 4Results posted
• Scoring Clinical Index For Onychomycosis in Toenail Onychomycosis Treating With Itraconazole CapsulesCompletedNCT00871728Phase 4Results posted
• Impact of Menstrual Cycle on Antiretroviral Pharmacokinetics in Healthy WomenCompletedNCT00869960Phase 4Results posted
• HIV Viremia and Persistence in Acutely HIV-Infected Patients Treated With Darunavir/Ritonavir and EtravirineTerminatedNCT00855413Phase 4Results posted
• A Single-arm, Open-label, Study to Assess the Pharmacokinetics of Darunavir and Ritonavir, Darunavir and Cobicistat, Etravirine, and Rilpivirine in HIV-1 Infected Pregnant WomenCompletedNCT00855335Phase 3Results posted
• Clarithromycin 500 mg Extended Release Tablets Under Fasting ConditionsCompletedNCT00840411Phase 1Results posted
• Clarithromycin 500 mg Extended Release Tablets Under Non-Fasting Conditions.CompletedNCT00840216Phase 1Results posted
• A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected PatientsCompletedNCT00838162Phase 2Results posted
• A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In ChildrenTerminatedNCT00836875Phase 3Results posted
• Clarithromycin 500 mg Tablets Under Non-Fasting ConditionsCompletedNCT00836706Phase 1Results posted
• Clarithromycin 500 mg Tablets Under Fasting ConditionsCompletedNCT00835692Phase 1Results posted
• Drug Interactions Between Voriconazole and Atazanavir Coadministered as Atazanavir/Ritonavir in Healthy ParticipantsCompletedNCT00833482Phase 1Results posted
• Ketoconazole Foam 2% for the Treatment of VersicolorCompletedNCT00830388Phase 4Results posted
• An Interaction Study to Assess Drug Levels in Fasting Healthy Adult SubjectsCompletedNCT00802074Not applicableResults posted
• A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast CancerCompletedNCT00798135Not applicableResults posted
• Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV DiseaseTerminatedNCT00775606Phase 4Results posted
• Phase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLCTerminatedNCT00769600Phase 2Results posted
• An Interaction Study to Assess Drug Levels in Healthy Adult SubjectsCompletedNCT00764465Phase 2Results posted
• Raltegravir vs. Atazanavir in Combination With Truvada® for the Treatment of Antiretroviral naïve HIV Infected PatientsCompletedNCT00762892Phase 4Results posted
• Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal InfectionCompletedNCT00739934Phase 2Results posted
• STUDY TO ASSESS THE LONG-TERM SAFETY OF EXTINA (KETOCONAZOLE) FOAM, 2%CompletedNCT00703846Phase 4Results posted
• Prospective Two-Year Study to Assess Miconazole Nitrate Resistance in Neonates and InfantsCompletedNCT00702507Phase 4Results posted
• Anidulafungin Candidemia/Invasive Candidiasis Intensive Care StudyCompletedNCT00689338Phase 3Results posted
• Assessment of Mechanisms of Improved Wound HealingCompletedNCT00673309Phase 2/3Results posted
• Ketoconazole, Hydrocortisone and Dutasteride in Asymptomatic Hormone Refractory Prostate CancerCompletedNCT00673127Phase 2Results posted
• Raltegravir + Lopinavir/Ritonavir or Emtricitabine/Tenofovir for HIV Treatment Naive SubjectsCompletedNCT00654147Phase 2Results posted
• Drug Interaction StudyCompletedNCT00646776Phase 1Results posted
• Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and PravastatinCompletedNCT00630734Phase 4Results posted
• A Study of Invirase (Saquinavir)/Ritonavir in HIV-Infected Infants and Children.CompletedNCT00623597Phase 2Results posted
• Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene)TerminatedNCT00620074Phase 4Results posted
• An Interaction Study to Assess Drug Levels in Healthy Adult SubjectsCompletedNCT00614991Not applicableResults posted
• Amiodarone for the Prevention of Reperfusion Ventricular FibrillationCompletedNCT00587483Not applicableResults posted
• Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's CycleCompletedNCT00586898Phase 2Results posted
• Ablation vs Drug Therapy for Atrial Fibrillation - Pilot TrialCompletedNCT00578617Not applicableResults posted
• Therapeutic Exploratory Study of Comparing Natamycin and Voriconazole to Treat Fungal Corneal UlcerCompletedNCT00557362Phase 1/2Results posted
• A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised AdolescentsCompletedNCT00556998Phase 2Results posted
• Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT)CompletedNCT00552240Phase 4Results posted
• This Is An Open-Label, Non-Comparative Study Designed To Evaluate A Short Course Of IV Anidulafungin, Followed Optionally By Oral Voriconazole, For The Treatment Of Candidemia And Invasive CandidiasisCompletedNCT00548262Phase 4Results posted
• Phase II Study of Thalidomide, Clarithromycin, Lenalidomide, and Dexamethasone for Newly Diagnosed Multiple MyelomaCompletedNCT00538733Phase 2Results posted
• Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating Patients With Prostate CancerTerminatedNCT00536991Phase 1/2Results posted
• A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).CompletedNCT00534352Phase 2Results posted
• Tipranavir/Ritonavir Low Dose Pharmacokinetics in Treatment Naive PatientsCompletedNCT00530920Phase 2Results posted
• Treatment of Aspergillus Fumigatus (a Fungal Infection) in Patients With Cystic FibrosisCompletedNCT00528190Phase 4Results posted
• A Study to Compare Effectiveness and Safety of Darunavir/Ritonavir (DRV/Rtv) 800mg/100mg Once Daily Versus DRV/Rtv 600mg/100mg Twice Daily in Early Treatment-Experienced HIV-1 Infected Patients (ODIN)CompletedNCT00524368Phase 3Results posted
• Comparison of TPV/r to DRV/r in Triple Class Experienced Patient With Resistance to > 1 PITerminatedNCT00517192Phase 3Results posted
• Pharmacokinetic Interactions Between Buprenorphine and Tipranavir/RitonavirCompletedNCT00486330Not applicableResults posted
• Treating Patients With Prostate Cancer That Did Not Respond to Hormone TherapyCompletedNCT00460031Phase 2Results posted
• HIV-1 Infection Study of Once a Day Versus Twice a Day Protease Inhibitor in Antiretroviral Treatment Naive AdultsCompletedNCT00450580Phase 3Results posted
• Lenalidomide, Dexamethasone, and Clarithromycin in Treating Patients Who Have Undergone Stem Cell Transplant for Multiple MyelomaCompletedNCT00445692Phase 2Results posted
• Induction/Simplification With Atazanavir + Ritonavir + Abacavir/Lamivudine Fixed-Dose Combination In HIV-1 InfectionCompletedNCT00440947Phase 3Results posted
• A Study of Saquinavir/Ritonavir in Liver-Impaired Patients With HIV Infection.CompletedNCT00435929Phase 1Results posted
• Prevention of Atrial Fibrillation Following EsophagectomyCompletedNCT00420017Phase 4Results posted
• Liposomal Amphotericin B (Ambisome) Versus Oral Voriconazole for the Prevention of Invasive Fungal InfectionsCompletedNCT00418951Phase 2Results posted
• Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee SurgeryCompletedNCT00393848Phase 2Results posted
• GRACE: A Study to Compare the Effectiveness, Safety and Tolerability of PREZISTA (Darunavir)/Ritonavir by Gender and Race When Administered With Other Antiretroviral Medications in Human Immunodeficiency Virus (HIV) Positive Women and Men.CompletedNCT00381303Phase 3Results posted
• Study of Lopinavir/Ritonavir Tablets Comparing Once-Daily Versus Twice-Daily Administration When Coadministered With Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-Experienced Human Immunodeficiency Virus Type 1 Infected SubjectsCompletedNCT00358917Phase 3Results posted
• Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.CompletedNCT00356915Phase 3Results posted
• Phase IIIb Study to Evaluate the Effectiveness and Safety of Atazanavir/Ritonavir as Single Enhanced Protease Inhibitor Therapy in Human Immunodeficiency Virus (HIV)-Infected Subjects Evidencing Virologic SuppressionCompletedNCT00337467Phase 3Results posted
• ALTAIR - Alternative Antiretroviral Strategies : a Comparison of Three Initial RegimensCompletedNCT00335322Phase 4Results posted
• Pharmacokinetics of Atazanavir/Ritonavir in HIV-1 Infected Pregnant WomenCompletedNCT00326716Phase 1Results posted
• Asthma Clinical Research Network (ACRN) Trial - Macrolides in Asthma (MIA)CompletedNCT00318708Phase 3Results posted
• To Determine The Amount Of Voriconazole In The Brain After 2 Loading Doses And 3 Maintenance Doses Over 3 DaysCompletedNCT00300677Phase 4Results posted
• Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung ResectionTerminatedNCT00300495Phase 3Results posted
• Maximal Suppression of the Androgen Axis in Clinically Localized Prostate CancerCompletedNCT00298155Phase 2Results posted
• A Study To Assess GW433908 (Fosamprenavir) Containing Regimens In HIV-1 Infected SubjectsCompletedNCT00296504Phase 3Results posted
• Voriconazole Versus Itraconazole In Primary Prophylaxis Of Invasive Fungal Infection (IFI) In Subjects With Allogeneic Hematopoietic Stem Cell Transplants (HSCT)CompletedNCT00289991Phase 3Results posted
• Voriconazole and Caspofungin Acetate in Treating Invasive Fungal Infections in Patients With Weakened Immune SystemsTerminatedNCT00238355Phase 2Results posted
• Voriconazole For Chronic Bronchopulmonary AspergillosisCompletedNCT00159822Phase 2/3Results posted
• Immediate vs. Deferred Empirical Antifungal Treatment With Voriconazole In Neutropenic PatientsCompletedNCT00150345Phase 3Results posted
• Kaletra Sex/Gender Pharmacokinetics (PK) StudyCompletedNCT00148759Phase 4Results posted
• Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell TransplantsCompletedNCT00143312Phase 4Results posted
• Prevention of Atrial Fibrillation Following Noncardiac Thoracic SurgeryCompletedNCT00127712Phase 4Results posted
• Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive AdultsCompletedNCT00118898Phase 3Results posted
• GEMINI Study - A Study of Saquinavir/Ritonavir in Treatment-Naive Patients With HIV-1 InfectionCompletedNCT00105079Phase 3Results posted
• Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101)CompletedNCT00075803Phase 3Results posted
• Atazanavir (BMS-232632) in Combination With Ritonavir or Saquinavir, and Lopinavir/Ritonavir, Each With Tenofovir and a Nucleoside in Subjects With HIVCompletedNCT00035932Phase 3Results posted
• Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate CancerTerminatedNCT00024167Phase 3Results posted
• A Study to Evaluate the Effect of Carbamazepine or Itraconazole on Radiprodil in Healthy Adult ParticipantsActive, not recruitingNCT07884734Phase 1
• A Study of the Effects of Itraconazole on LY4395089 in Healthy ParticipantsCompletedNCT07592572Phase 1
• Administration of Repurposed Ketoconazole in Glioma PatientsActive, not recruitingNCT07585851Early Phase 1
• Comparison of Combination of Itraconazole and Isotretinoin Versus Itraconazole Alone in the Treatment of Resistant Trichophyton InfectionCompletedNCT07420894Not applicable
• Helicobacter Pylori Infection and Gastric Disease in Bhutan: First Community-Wide, Population-Based StudyCompletedNCT07211880Not applicable
• Effects of Different Antibiotic Regimens in Preterm Premature Rupture of MembranesCompletedNCT07148622Not applicable
• Efficacy Comparison of Itraconazole Pulse Therapy and Terbinafine Therapy in Treatment of Tinea Capitis in Children.CompletedNCT07068256Not applicable
• Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy AdultsTerminatedNCT06965881Phase 1
• Clinical Study Aiming to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Administration of ZE50-0134 at 5 Dose Levels in Healthy VolunteersCompletedNCT06787131Phase 1
• Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast CancerCompletedNCT06710990Phase 1
• A Phase 1 Study to Examine the Effects of Itraconazole After Single Dose Administration of Varegacestat (AL102) to Healthy ParticipantsCompletedNCT06677996Phase 1
• A Study to Assess the Effect of Voriconazole and Quinidine on the Pharmacokinetics of a Single Dose of Repotrectinib in Healthy ParticipantsCompletedNCT06493409Phase 1
• Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy VolunteersCompletedNCT06399315Phase 1
• A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy ParticipantsCompletedNCT06357520Phase 1
• Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in EgyptiansCompletedNCT06315478Phase 4

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