Cyclooxygenase Inhibitors: all 2,871 studies that test it

Page 12 of 29. Open to participants first (296), then studies with results posted, then the rest; newest registration first within each.

• Clinical Efficacy of Indomethacin in Early Treatment of Acute PancreatitisStatus unknownNCT05637281Not applicable
• Evaluation of Effect of Intravenous Morphine vs Intravenous Ibuprofen and Acetaminophen vs Intravenous IbuprofenCompletedNCT05630222Phase 3
• Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After ThyroidectomyStatus unknownNCT05626010Not applicable
• Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults.CompletedNCT05625334Phase 1
• Ibuprofen Versus Ketorolac for Perioperative Pain Control After Open HysterectomyCompletedNCT05610384Not applicable
• Platelet Enzymatically Oxidized Phospholipids (eoxPL) Characterisation in a Healthy Cohort on and Off AspirinCompletedNCT05604118Not applicable
• Effectiveness of Pre-emptive Analgesics on Post-Operative Pain After Stainless Steel Crown Placement On Primary MolarsCompletedNCT05602064Phase 4
• Opioid-Free Pain Control Regimen Following Robotic Radical ProstatectomyTerminatedNCT05597878Phase 2/3
• Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.Status unknownNCT05582421Early Phase 1
• Safety of Ibuprofen After Major Orthopaedic SurgeriesCompletedNCT05575700Phase 4
• Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized StudyStatus unknownNCT05554822Phase 3
• Probiotic Supplementation During Pregnancy in Preeclampsia High-risk GroupsStatus unknownNCT05554185Not applicable
• Multimodal and Unimodal Analgesia in CholecystectomyCompletedNCT05547659Phase 1/2
• Comparison of the Effect of Medication Therapy in Alleviating Migraine With Patent Foramen OvaleCompletedNCT05546320Phase 2
• Determination of Pharmacokinetics of Different Curcuminoids Preparations: Pilot StudyCompletedNCT05542394Not applicable
• Effects of Nigella Sativa Oil on Pain Intensity and Physical Functions in Patients With Knee OsteoarthritisCompletedNCT05541185Not applicable
• Comparative Bioavailability Study Between Etoricoxib and Tramadol, Administered Individually or in CombinationCompletedNCT05533073Phase 1
• Bioequivalence Study of Etoricoxib in Healthy Adult Subjects Under Fasting ConditionCompletedNCT05532280Phase 1
• Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic EventsCompletedNCT05515120Phase 2/3
• Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk PatientsActive, not recruitingNCT05514847Phase 4
• The Effects of NSAIDs on Bone Metabolism Following ExerciseCompletedNCT05512013Phase 1
• Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Laparoscopic Gynecology SurgeryStatus unknownNCT05509244Not applicable
• Injection of Tenoxicam Versus Arthrocentesis Alone in the Treatment of Temporomandibular Joint OsteoarthritisCompletedNCT05497570Phase 1
• Oral Ibuprofen Versus Placebo in Treatment of Patent Ductus Arteriosus (PDA)in Preterm InfantsCompletedNCT05493540Phase 2
• Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.CompletedNCT05488925Phase 4
• Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third MolarsCompletedNCT05484401Phase 3
• Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve BlockStatus unknownNCT05479175Not applicable
• Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid ExposureActive, not recruitingNCT05463367Phase 2
• Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female VolunteersCompletedNCT05438303Phase 1
• A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult SubjectCompletedNCT05436678Phase 1
• Study of Nonsteroidal Anti-inflammatory Drugs in People With Painful Knee OsteoarthritisActive, not recruitingNCT05430230Phase 4
• Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen, Tablets Administered Individually or in CombinationCompletedNCT05428306Phase 1
• Treating Immuno-metabolic Depression With Anti-inflammatory DrugsCompletedNCT05415397Phase 3
• Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D SupplementsCompletedNCT05414838Not applicable
• Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion SurgeryCompletedNCT05413902Phase 4
• The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) StudyStatus unknownNCT05402124Phase 2
• Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder SurgeryCompletedNCT05401916Not applicable
• Efficacy of NSAID and Acetaminophen in the Control of Post-Operative Pain in Patients Undergoing Total Knee ReplacementCompletedNCT05393414Not applicable
• Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic TreatmentStatus unknownNCT05383820Phase 4
• A Pharmacokinetic Study of Intravenous NTM-001 in Healthy Chinese SubjectsCompletedNCT05382546Phase 1
• Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWICompletedNCT05377242Not applicable
• Drug-Drug Interaction Study of "CG-651" in Healthy VolunteerCompletedNCT05370716Phase 1
• Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination on Postoperative Opioid ConsumptionCompletedNCT05366777Not applicable
• NF-1, Nutraceutical InterventionActive, not recruitingNCT05363267Phase 1
• Ketorolac-an Option for Post Operative Pain Management After Elective Cardiac Surgery.CompletedNCT05361824Phase 4
• Assessing the Bioavailability of Leading Phytonutrient ProductsStatus unknownNCT05349032Not applicable
• The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle DamageStatus unknownNCT05346211Not applicable
• Preoperative Aspirin and Benzydamine Hydrochloride Gargles on Severity and Duration of Post-Operative Sore ThroatStatus unknownNCT05343429Phase 4
• Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Teeth With Symptomatic Irreversible PulpitisStatus unknownNCT05341999Phase 1
• A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal AdenocarcinomaActive, not recruitingNCT05336266Early Phase 1
• Pharmacokinetics and Bioavailability of Curcumin UP 30 Capsules in Healthy Adult SubjectsStatus unknownNCT05334043Phase 1
• To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Modified-Release Tablets 800 mgCompletedNCT05329454Phase 1
• Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal CancerStatus unknownNCT05327751Phase 3
• Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee ArthroplastyCompletedNCT05324995Phase 2
• Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following BunionectomySuspendedNCT05324358Phase 3
• Evaluate Efficacy and Safety of X0002 in Treatment of Knee OsteoarthritisCompletedNCT05324163Phase 3
• Comparative Study Between Vaginal Progesterone Alone or Combined With Aspirin in Prevention of Recurrent Preterm BirthCompletedNCT05319834Phase 4
• Diclofenac Gel in the Treatment of Cervicogenic HeadacheWithdrawnNCT05312645Phase 3
• Outcomes of Rivaroxaban and Aspirin in PAD After Endovascular RevascularizationStatus unknownNCT05308030Early Phase 1
• Drug-drug Interactions Between DWP14012 and Aspirin in Healthy SubjectsCompletedNCT05304845Phase 1
• Platelet Aggregation in Diabetic Patients With Acute Coronary Syndrome Treated With Different Doses of AspirinCompletedNCT05293808Phase 4
• The Effect of Different Intra-articular Injections Primary GonarthrosisCompletedNCT05291793Not applicable
• Celecoxib in Postoperative Analgesia for Radius Fracture SurgeryCompletedNCT05288374Phase 4
• Chidamide + Celecoxib in Advanced Metastatic Colorectal Cancer (CCmCC)TerminatedNCT05281276Phase 1
• GM03 - Platelet RNA Signatures of AspirinCompletedNCT05278637Early Phase 1
• Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted CoilingCompletedNCT05257824Phase 4
• Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis BStatus unknownNCT05256823Phase 2
• Biomarkers for Prediction of Analgesic Efficacy in Knee OA.CompletedNCT05256342Not applicable
• Effect of Combination Non Steroidal Antiinflammatory Drugs and Narrowband UVB Treatment in Non-PhotoadaptersTerminatedNCT05256147Not applicable
• A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy SubjectsCompletedNCT05254548Phase 1
• Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE)CompletedNCT05253781Phase 3
• Effect of Psychosocial and Psychophysical Factors and Preemptive Analgesia on Postoperative Pain in Upper Limb SurgeryStatus unknownNCT05248152Not applicable
• Immune Diversity Response to Oral Dosing of Nutritional Health Products in Healthy ParticipantsCompletedNCT05242718Not applicable
• Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and IlaprazoleCompletedNCT05237297Phase 1
• A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult SubjectsCompletedNCT05232461Phase 1
• 162 mg of Aspirin for Prevention of PreeclampsiaStatus unknownNCT05221164Phase 4
• Evaluation of the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of MigraineTerminatedNCT05211154Phase 4
• Low Dose Versus Normal Dose Ketorolac for Postoperative Pain After Prostatectomy and HysterectomyCompletedNCT05206110Not applicable
• Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST)CompletedNCT05193071Phase 4
• Ibuprofen Versus Ketorolac for Pain Relief During HysterosalpingogramTerminatedNCT05190341Phase 4
• Analgesia for Thyroidectomy Using Bilateral Superficial Cervical Plexus Block With Bupivacaine Only or Adding Ketorolac to it.CompletedNCT05180214Phase 2
• Comparative Pharmacokinetic, Pharmacodynamic, and Safety Study of 1 Dose Level of Aspirin for Injection and Oral Aspirin Tablets in Healthy Adult Human SubjectsCompletedNCT05166096Phase 1
• Molecular Effects of Aspirin & Metformin on Colonic EpitheliumWithdrawnNCT05158374Not applicable
• Pain Management After SurgeryStatus unknownNCT05154682Phase 3
• Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery.CompletedNCT05150431Phase 4
• Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic AppliancesCompletedNCT05147376Early Phase 1
• Comparison of the Anti-Inflammatory Efficacy of Preemptive Dexamethasone and EtoricoxibStatus unknownNCT05142098Early Phase 1
• Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee ArthroplastyStatus unknownNCT05132595Not applicable
• Efficacy of Chronoterapy in Oral SurgeryCompletedNCT05126264Not applicable
• Fasting Comparative Bioavailability Study of 2 Meloxicam 15 mg Tablets in Healthy Volunteers Under Fasting ConditionCompletedNCT05125588Phase 1
• Effects of Edoxaban on Platelet AggregationCompletedNCT05122455Phase 2/3
• Local Anesthesia Versus Combined Local Anesthesia With Single Dose Analgesia on Pain Control During Thoracic Ultrasound Guided ProceduresStatus unknownNCT05121233Phase 4
• A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.Active, not recruitingNCT05109312Phase 4
• Efficacy of Rectal Indomethacin in Prevention of Post-operative Pancreatitis After PancreaticoduodenectomyCompletedNCT05109143Not applicable
• Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE DiabetesActive, not recruitingNCT05105919Early Phase 1
• A Comparative Study of Indobufen and Aspirin in Patients With Coronary AtherosclerosisStatus unknownNCT05105750Phase 4
• PK Evaluation of a Nanoformed Oral IR Piroxicam Tablet in Healthy SubjectsCompletedNCT05104931Phase 1
• SAVES-IBD: Safety & Efficacy of Aspirin vs. Standard of Care for VTE Prophylaxis After IBD SurgeryWithdrawnNCT05104229Phase 3
• Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve BlockCompletedNCT05097768Not applicable
• Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)WithdrawnNCT05085574Phase 2

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