Cyclobenzaprine: all 42 studies that test it

Page 1 of 1. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingNCT07840183Phase 4
• Cyclobenzaprine for Postoperative Pain in Minimally Invasive HysterectomyNot yet recruitingNCT07664956Phase 4
• A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)RecruitingNCT07621237Phase 2
• Comparing Adjuvant Treatments for High Tone Pelvic Floor DysfunctionRecruitingNCT07404397Phase 2/3
• Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)RecruitingNCT06636786Phase 2
• A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 InfectionCompletedNCT05472090Phase 2Results posted
• A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL Taken Daily in Patients With FibromyalgiaCompletedNCT05273749Phase 3Results posted
• A Phase 3 Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With FibromyalgiaCompletedNCT04508621Phase 3Results posted
• A Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With FibromyalgiaCompletedNCT04172831Phase 3Results posted
• A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Participants With PTSDTerminatedNCT03841773Phase 3Results posted
• A 40-week Study to Evaluate TNX-102 SL 5.6 mg Taken Daily at Bedtime in Patients With PTSDCompletedNCT03508700Phase 3Results posted
• Driving Simulation to Assess Non-Sedative Effects of TolperisoneCompletedNCT03353922Phase 1Results posted
• Bioequivalence Study of TNX-102 SL 2.8 mg Sublingual Tablets From Two Manufacturers.CompletedNCT03168022Phase 1Results posted
• 12-Week Open-Label Extension Study of TNX-102 SL in PTSD PatientsTerminatedNCT03110575Phase 3Results posted
• Safety and Efficacy Study of TNX-102 SL in Patients With Military-related PTSDTerminatedNCT03062540Phase 3Results posted
• Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With FibromyalgiaTerminatedNCT02829814Phase 3Results posted
• Cyclobenzaprine HCl Extended Release 15 mg Versus Placebo in Treatment of Cervical and/or Lower Back Pain Due to Muscle Spasms of Local OriginCompletedNCT02814565Phase 3Results posted
• A 3-Month Open-Label Safety and Efficacy Study of TNX-102 SL Tablets in Fibromyalgia PatientsCompletedNCT02589275Phase 3Results posted
• A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgiaCompletedNCT02436096Phase 3Results posted
• Open Label Extension Safety and Efficacy Study of TNX-102 SL Tablets in Military Related PTSD and Related ConditionsCompletedNCT02421679Phase 2Results posted
• Safety and Efficacy Study of TNX-102 SL in Subjects With Military-Related PTSD and Related ConditionsCompletedNCT02277704Phase 2Results posted
• 12-Month Open-Label Long-term Safety Study of TNX-102 SL Tablets in Fibromyalgia PatientsCompletedNCT02015234Phase 3Results posted
• Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer PatientsTerminatedNCT01921296Phase 2Results posted
• BEdtime Sublingual TNX-102 SL as Fibromyalgia Intervention Therapy (BESTFIT)CompletedNCT01903265Phase 2/3Results posted
• A Randomized Study of Three Medication Regimens for Acute Low Back PainCompletedNCT01587274Phase 4Results posted
• A Comparative Bioavailability and Pharmacokinetic Study of TNX-102 2.4 mg and Cyclobenzaprine 5 mg Tablets in Healthy Adults.CompletedNCT01490788Phase 1Results posted
• Cyclobenzaprine Extended Release (ER) for FibromyalgiaTerminatedNCT01041495Phase 4Results posted
• Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow ParametersCompletedNCT01028014Not applicableResults posted
• Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical TrialCompletedNCT00790270Phase 2Results posted
• A Single-Dose, Randomized, Open-Label, 2-Way Crossover Study to Evaluate the Dose-Proportionality, Safety, and Tolerability of TNX-102 SL (Cyclobenzaprine HCl Sublingual Tablets) in Healthy Japanese and Chinese SubjectsCompletedNCT07464535Phase 1
• A Phase 1, Open-Label, Parallel-Group, Single-Dose Study To Compare The Pharmakokinetics Of TNX-102 SL (Cyclobenzaprine Hydrochloride Sublingual Tablet) In Non-Elderly Versus Elderly ParticipantsActive, not recruitingNCT07413367Phase 1
• Safety and Efficacy Study of TNX-102 SL in Participants With PTSDWithdrawnNCT05372887Phase 2
• Dose-Proportionality and Food Effect Study of TNX-102 SLCompletedNCT04164719Phase 1
• Steady-State Pharmacokinetic Comparison Study of TNX-102 SL 5.6 mg Versus AMRIX® 30 mg ER CapsulesCompletedNCT03443960Phase 1
• Cyclobenzaprine in Muscle Cramps With Liver CirrhosisStatus unknownNCT02642861Phase 3
• Comparative Pharmacokinetics and Safety of 3 Different Formulations of TNX-102 2.8 mg SL Tablets and Cyclobenzaprine 5 mg Oral Tablet in Healthy AdultsCompletedNCT01889173Phase 1
• Study Comparing A New Drug Containing The Combination Meloxicam And Cyclobenzaprine In The Treatment Of Acute LumbagoWithdrawnNCT01587508Phase 3
• Efficacy and Safety of Cyclobenzaprine Hydrochloride Extended Release for the Treatment of Chronic MigraineTerminatedNCT01151787Phase 3
• Use of Cyclobenzaprine After Vaginal SurgeryCompletedNCT01081990Not applicable
• To Demonstrate the Relative Bioavailability of Cyclobenzaprine HCl TabletsCompletedNCT00913419Phase 1
• Bioequivalence Study of Cyclobenzaprine Hydrochloride 10 mg Tablets, USP Under Fasting ConditionsCompletedNCT00778037Not applicable
• An Effectiveness and Safety Study of Cyclobenzaprine HCl Alone or in Combination With Ibuprofen for Acute Back or Neck Muscle Pain With Muscle SpasmCompletedNCT00246389Phase 4

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