Cholinesterase Inhibitors: all 505 studies that test it

Page 3 of 6. Open to participants first (34), then studies with results posted, then the rest; newest registration first within each.

• Different Doses of Neostigmine for Reversal of Moderate Neuromuscular Blockade in ChildrenStatus unknownNCT05053594Phase 4
• Comparative Efficacy and Safety of Sugammadex and NeostigmineStatus unknownNCT04997759Not applicable
• Nebulized Dexmedetomidine Versus Neostigmine/Atropine in Postdural Puncture HeadacheCompletedNCT04910477Phase 3
• Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture HeadacheStatus unknownNCT04905953Phase 2/3
• Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid SurgeryCompletedNCT04873531Not applicable
• The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood FlowTerminatedNCT04777383Not applicable
• Reversal of Neuromuscular Blockade and Perioperative ArrhythmiasCompletedNCT04720573Not applicable
• Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCICompletedNCT04671030Phase 1
• Functional Dyspepsia: Validation of a Questionnaire for Symptom Assessment in FD PDS SubgroupCompletedNCT04647955Phase 4
• Neostigmine and Dexamethasone in Adductor Canal BlockCompletedNCT04565301Not applicable
• Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical MastectomyCompletedNCT04544228Not applicable
• A Phase III Trial of Z-338 in Paediatric Patients With Functional DyspepsiaCompletedNCT04526119Phase 3
• Clinical Study of Huperzine A in the Treatment of Patients With Hypertensive Cerebral HemorrhageStatus unknownNCT04509323Phase 4
• Addition of Neostigmine to LevobupivacaineCompletedNCT04492319Not applicable
• Functional Dyspepsia: Validation of the Leuven Postprandial Distress Scale (LPDS) in a Placebo-controlled TrialCompletedNCT04464369Phase 4
• Efficiency of Donepezil in Elderly Patients for Prevention of POCD DysfunctionStatus unknownNCT04423276Phase 4
• IM Neostigmine for Accelerating Bladder Emptying After CS by Spinal AnesthesiaCompletedNCT04364607Phase 4
• Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIVCompletedNCT04353778Phase 1/2
• Pyridostigmine in Severe SARS-CoV-2 InfectionStatus unknownNCT04343963Phase 2/3
• Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative DeliriumCompletedNCT04189666Phase 1/2
• Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke AphasiaCompletedNCT04134416Phase 3
• Adjuvant Use of Neostigmine in Sepsis and Septic Shock.CompletedNCT04130230Phase 2
• Effectiveness of Prokinetic Agents in Improving Abdominal Discomfort at ColonoscopyStatus unknownNCT04104867Not applicable
• Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture HeadacheCompletedNCT03997006Phase 4
• Noradrenaline, Acetylcholine and Dynamic Learning in Healthy HumansCompletedNCT03957174Not applicable
• The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.Status unknownNCT03907371Phase 2
• Cholinergic Neurotransmission in Mobility and Cognition in Parkinson DiseaseCompletedNCT03840837Phase 4
• The Use of Sugammadex in the Critically IllStatus unknownNCT03791801Not applicable
• A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male VolunteersCompletedNCT03698695Phase 1
• Itopride in Feeding Intolerance of Critically-ill Patients Receiving Enteral NutritionStatus unknownNCT03698292Not applicable
• Improving Walking Automaticity in Parkinson's Disease: Levodopa or DonepezilCompletedNCT03599726Early Phase 1
• Intrathecal Neostigmine for Prevention of PDPHCompletedNCT03587441Phase 4
• Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn SurgeryCompletedNCT03513406Phase 3
• Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia GravisStatus unknownNCT03510546Phase 4
• Comparison Between Intraperitoneal Versus Intramuscular Neostigmine on Pattern of Postoperative GIT Motility in Patients Undergoing Laparoscopic CholecystectomyStatus unknownNCT03505255Phase 4
• A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS)CompletedNCT03438604Phase 1
• A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body LocationsCompletedNCT03432195Phase 1
• Effect of Acotiamide on Gastric Motility and Satiation in Healthy VolunteersCompletedNCT03402984Not applicable
• A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery SystemCompletedNCT03397862Phase 1
• Combined Use of Low-dose Sugammadex Plus Neostigmine Administered for Reversal of RocuroniumStatus unknownNCT03328312Early Phase 1
• Neostigmine For Snoring During DISETerminatedNCT03316963Early Phase 1
• Pyridostigmine as Immunomodulator in People Living With HIVSuspendedNCT03312244Phase 2
• Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic SurgeryCompletedNCT03292965Not applicable
• Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTSCompletedNCT03261570Early Phase 1
• A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept®CompletedNCT03259958Phase 1
• Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee SurgeryCompletedNCT03248648Phase 2/3
• Intra-articular Dexmedetomidine Versus Neostigmine After Knee Arthroscopy (a Comparative Study)CompletedNCT03212495Phase 2/3
• A Multinational, Multi-center, Randomized, Double-blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's DiseaseCompletedNCT03197740Phase 3
• Bioavailability, Safety, and Tolerability of BIS-001 ERCompletedNCT03156439Phase 1
• Vagal Stimulation in POTSActive, not recruitingNCT03124355Phase 1
• Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Alzheimer's DiseaseStatus unknownNCT03090516Phase 2/3
• AchE Inhibitor and InsulinCompletedNCT03063515Phase 1
• Effect of Neostigmine on the Recovery of Rocuronium: A Comparison Between Partial and TOF Ratio-Based DoseCompletedNCT03058263Phase 1/2
• Neostigmine Versus Dexamethasone as Adjuvants to Lidocaine During Intravenous Local AnesthesiaCompletedNCT03021772Phase 2/3
• Racial Differences in Vagal Control of Glucose Homeostasis, Chronic StudyWithdrawnNCT03014323Phase 1
• Anticholium® Per SeCompletedNCT03013322Not applicable
• Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson DiseaseStatus unknownNCT03011476Phase 4
• Memory and Mental Health in AgingCompletedNCT02988908Phase 4
• A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®CompletedNCT02968719Phase 1
• SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4CompletedNCT02941328Phase 2
• Donepezil Attenuate Postoperative Cognitive DysfunctionStatus unknownNCT02927522Phase 3
• A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson PatientsWithdrawnNCT02857244Phase 2
• Efficacy of RIVAstigmine on Motor, Cognitive and Behavioural Impairment in Progressive Supranuclear PalsyCompletedNCT02839642Phase 3
• Prevention of Postoperative Events Following Reversal With Sugammadex or NeostigmineTerminatedNCT02825576Phase 4
• Sugammadex/Neostigmine and Liver TransplantationCompletedNCT02697929Not applicable
• Safety, Tolerability and Pharmacokinetics of DKF-310 ( (Donepezil).CompletedNCT02695004Phase 1
• Sugammadex Versus Neostigmine for Postoperative Nausea and Vomiting After Laparoscopic Gynaecological SurgeryCompletedNCT02666014Phase 3
• Optimal Dose Escalation Strategy to Successful Achievement of High Dose Donepezil 23mgCompletedNCT02550665Phase 3
• Echothiophate Iodide for the Prevention of Progression of MyopiaWithdrawnNCT02544529Phase 4
• Quality of Awakening and Impact on Cognitive Function After Administration of Sugammadex in Robotic Radical CystectomyCompletedNCT02454504Not applicable
• Effect of Donepezil on Cognition in Parkinson's Disease With Mild Cognitive Impairment (PD-MCI)Status unknownNCT02450786Phase 2
• Open Label Trial of Rivastigmine Patch in Subjects With Mild to Moderate Stage AD Having Coexisting svCVDCompletedNCT02444637Phase 4
• Neostigmine Reversal And Neuromuscular RecoveryCompletedNCT02433808Phase 4
• Sugammadex and Cognitive FunctionCompletedNCT02419352Not applicable
• The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With DementiaStatus unknownNCT02415062Phase 2
• Sugammadex Versus Neostigmine in Patients With Liver Cirrhosis Undergoing Liver ResectionCompletedNCT02414880Phase 4
• Rivastigmine Patch Effect on the Post-operative Delirium in Patients at Risk of Dementia.CompletedNCT02413554Phase 4
• "Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"CompletedNCT02375217Phase 4
• Pharmacovigilance in Gerontopsychiatric PatientsTerminatedNCT02374567Phase 3
• Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCICompletedNCT02370862Early Phase 1
• Use of Prokinetics During Inpatient Bowel Care for SCI PatientsStatus unknownNCT02370433Phase 1
• A Pilot Study of Pyridostigmine in Pompe DiseaseTerminatedNCT02357225Early Phase 1
• A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB)CompletedNCT02345213Phase 4
• Donepezil Memory Preservation Post ECTTerminatedNCT02331771Not applicable
• Comparison of the Effects of Neostigmine With Sugammadex on Postoperative Nausea and Vomiting.CompletedNCT02286752Phase 4
• Galantamine Effects in Patients With Metabolic SyndromeCompletedNCT02283242Phase 4
• Multicenter Evaluation of Memory Remediation After TBI With DonepezilCompletedNCT02255799Phase 3
• Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3CompletedNCT02227823Phase 2
• Effects of Donepezil on Regional Cerebral Blood Flow Following Aneurysmal Subarachnoid HaemorrhageTerminatedNCT02222727Phase 2
• Evaluation if Physostigmine Reduces Symptoms in Patients Who Has Developed a Delirium in Intensive Care After a SurgeryStatus unknownNCT02216266Phase 3
• Intraocular Pressure Changes Associated With Tracheal Extubation: Comparison of Sugammadex With Conventional Reversal of Neuromuscular BlockadeCompletedNCT02215382Phase 4
• Clinical Trial of Deferasirox Combination Treatment With Deferiprone In Thalassaemia PatientsCompletedNCT02198508Not applicable
• A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects.CompletedNCT02178124Phase 1
• Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)CompletedNCT02171988Phase 4
• Symptomatic Treatment of Vascular Cognitive ImpairmentStatus unknownNCT02098824Phase 2/3
• A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.CompletedNCT02094053Phase 2
• Role of Vitamin C to Augment Iron Chelation With DFP or DFXStatus unknownNCT02083575Phase 2/3
• Brain Changes by Rivastigmine According to Butyrylcholinesterase AllelesStatus unknownNCT02063269Not applicable
• A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or DonepezilCompletedNCT02055703Phase 1
• Discontinuation of Cholinesterase Inhibitors for the Treatment of Severe Alzheimer's DiseaseCompletedNCT02035982Phase 3

← Cholinesterase Inhibitors overview