Cholinergic Antagonists: all 1,354 studies that test it

Page 9 of 14. Open to participants first (141), then studies with results posted, then the rest; newest registration first within each.

• Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Adult Patients Undergoing Lower Extremity Surgery Under Spinal AnesthesiaTerminatedNCT03322150Not applicable
• Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal AnesthesiaCompletedNCT03322098Not applicable
• Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With ReferenceCompletedNCT03302065Phase 1
• MRI Measurement of the Effects of Deep Neuromuscular Blockade on the Abdominal Working Space During LaparoscopyStatus unknownNCT03287388Not applicable
• Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After SurgeryStatus unknownNCT03280316Not applicable
• Influence of Mechanical Ventilation Modes on the Efficacy of Nebulized BronchodilatorStatus unknownNCT03271905Not applicable
• Motion Sickness Medications and Vestibular Time ConstantCompletedNCT03270839Phase 4
• Functional Respiratory Imaging Study (FRI)CompletedNCT03268226Phase 3
• Efficiency of Twice Daily Formoterol Versus Once Daily Tiotropium in Patients With GOLD A/B COPDStatus unknownNCT03258749Not applicable
• Meclizine for Hepatocellular CarcinomaCompletedNCT03253289Phase 1
• Two-period 21 Day Cross-over Study to Compare the Pharmacokinetics of Tiotropium From Two InhalersCompletedNCT03246581Phase 1
• Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract SurgeryCompletedNCT03243500Phase 4
• Reclassifying Constipation Using Imaging and ManometryStatus unknownNCT03226145Not applicable
• GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip FractureWithdrawnNCT03226080Phase 4
• The Influence of Atropine on Choroidal ThicknessCompletedNCT03158142Phase 4
• Bioavailability, Safety, and Tolerability of BIS-001 ERCompletedNCT03156439Phase 1
• Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With A Reference ProductCompletedNCT03155204Early Phase 1
• INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and OlodaterolCompletedNCT03152149Phase 4
• The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)Active, not recruitingNCT03140358Phase 3
• Effectiveness Study of Scopolamine Combined With Escitalopram in Patients With MDDCompletedNCT03131050Phase 4
• The Effects of Inhaled Aclidinium Bromide/Formoterol Fumarate on Inspiratory Pleural Pressures in SmokersCompletedNCT03104634Phase 3
• Effect of Plum-blossom Needle vs. Tropicamide Eye Drops on Juvenile MyopiaStatus unknownNCT03097198Not applicable
• Continuous Infusion Versus Intermittent Bolus Injection of RocuroniumStatus unknownNCT03060707Phase 4
• Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk WomenCompletedNCT03055390Phase 4
• Muscarinic Receptor Antagonists as a Therapy for Diabetic NeuropathyCompletedNCT03050827Phase 3
• Benefits of Glycopyrrolate on Intubation With Rigid-videostylet (OptiScope®)CompletedNCT03050242Not applicable
• Rocuronium Effective Dose for Laparoscopic CholecystectomyCompletedNCT03043157Phase 3
• Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy VolunteersCompletedNCT03030105Phase 1
• Autonomic Blockade and Endogenous Glucose ProductionWithdrawnNCT03028571Phase 1
• Pharmacokinetic Interaction and the Safety of Inhaled CHF5259 and CHF6001CompletedNCT03004495Phase 1
• Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD TherapeuticsActive, not recruitingNCT03002389Phase 2
• Tiotropium/Formoterol Via Discair® vs Tiotropium Monotherapy or Tiotropium + Formoterol Free Combination TreatmentCompletedNCT02988869Phase 4
• To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain.Status unknownNCT02985671Phase 3
• Lung Deposition of Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide Administered Via pMDI in Healthy, Asthmatic and COPD PatientsCompletedNCT02975843Phase 1
• The Use of Topical Oxybutynin 10% for Treating Primary Focal Hyperhidrosis-axillary, Palmar and Plantar.CompletedNCT02973659Not applicable
• Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC TrialCompletedNCT02972476Phase 4
• The Effects of Preoperative Scopolamine Patch Application on the Postoperative Nausea and Vomiting in MVD SurgeryStatus unknownNCT02968082Phase 4
• Multimodal Narcotic Limited Perioperative Pain Control With Colorectal SurgeryStatus unknownNCT02958566Phase 4
• Combined Atropine With Orthokeratology in Childhood Myopia Control (AOK) -A Randomized Controlled TrialCompletedNCT02955927Not applicable
• Effect of a LAMA and a uLABA on the Methacholine Dose-response CurveCompletedNCT02953041Phase 4
• Safety and Pharmacokinetic Characteristics After Administration of HIP1503 and HGP1103 in Healthy Male VolunteersCompletedNCT02940314Phase 1
• Atracurium Mixed With Magnesium Sulfate Versus Atracurium Alone as Adjuvant to Lidocaine in IVRACompletedNCT02920905Phase 3
• Effectiveness of Bethanechol Chloride and Early Bladder Training for Prevention of Bladder Dysfunction After Radical Hysterectomy in Cervical Cancer Stage IB - IIACompletedNCT02910596Phase 4
• Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/FluSuspendedNCT02904304Phase 3
• Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular BlockTerminatedNCT02888067Phase 1
• Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®Status unknownNCT02880787Not applicable
• Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status AsthmaticusCompletedNCT02872597Phase 1
• Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02872090Phase 4
• The Effects of Low Concentration Atropine on Pupil Size and AccommodationCompletedNCT02870478Phase 3
• The Effect of Hyoscine Butylbromide on Shortening of First and Second Stages of LaborCompletedNCT02839213Phase 2
• Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus TrospiumCompletedNCT02831231Phase 1
• Efficacy and Safety of Tamsulosin/Solifenacin Combination Therapy in Patients With Voiding Symptoms and Moderate to Severe Storage Symptoms Due to Benign Prostate HyperplasiaStatus unknownNCT02827578Phase 3
• Prevention of Postoperative Events Following Reversal With Sugammadex or NeostigmineTerminatedNCT02825576Phase 4
• Effect of Intravenous Hyoscine Butylbromide Injection on First Stage Labour in PrimigavidaeCompletedNCT02824679Phase 4
• A Study to Evaluate Safety, Tolerability and Pharmacokinetics of DA-8010 in Healthy SubjectsStatus unknownNCT02821312Phase 1
• Thorough QT (TQT) Study of TD-4208 in Healthy SubjectsCompletedNCT02820311Phase 1
• The Application of Spasmolytic in PCLE Examination of Superior Gastrointestinal EndoscopeCompletedNCT02811341Phase 1
• Continuous NMB in PCASCompletedNCT02790164Phase 2
• Bronchodilator's Effects on Exertional Dyspnoea in Pulmonary Arterial HypertensionWithdrawnNCT02782052Phase 3
• Neuromuscular Blockade for Optimising Surgical Conditions During Spinal SurgeryStatus unknownNCT02778945Phase 4
• TD-4208 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male SubjectsCompletedNCT02772159Phase 1
• Atropine in Laparoscopic Gynaecological SurgeryStatus unknownNCT02769325Phase 4
• Atrovent in Exercise Induced Laryngeal Obstruction (EILO)CompletedNCT02755714Phase 1/2
• A Study Comparing the Closed Triple Therapy, Open Triple Therapy and a Dual Therapy for Effect on Lung Function in Subjects With Chronic Obstructive Pulmonary Disease (COPD)WithdrawnNCT02731846Phase 3
• Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in AutonomicActive, not recruitingNCT02726711Phase 1
• Effect of Buscopan on Gastrointestinal Imaging Quality With Probe-based Confocal Laser EndomicroscopyStatus unknownNCT02725398Not applicable
• Study to Evaluate the Clinical Efficacy and Safety of Tamsulosin Alone or in Combination With Solifenacin for the Treatment in Men With Lower Urinary Tract Symptoms Including Overactive Bladder SymptomsCompletedNCT02715024Phase 4
• Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent VaccineActive, not recruitingNCT02710851Phase 2
• Hyoscine Butyl Bromide in Reducing Pain During HSGCompletedNCT02709603Phase 4
• The Effect of Propofol and Remifentanil Sequence on ED50 and ED95 of Rocuronium in Rapid Sequence Induction AnesthesiaCompletedNCT02709473Phase 4
• Atropine for Preventing Ventilator-Associated PneumoniaCompletedNCT02704923Phase 2
• Urinary Biomarkers in Overactive Bladder in ChildrenStatus unknownNCT02704013Not applicable
• Cerebral NIRS Profiles During Premedication for Neonatal IntubationCompletedNCT02700893Phase 2/3
• Pediatric Inguinal Hernia Repair: Are Muscle Relaxants Necessary? Endotracheal Intubation vs Laryngeal Mask AirwayCompletedNCT02696837Not applicable
• A Study to Compare Fluticasone /Formoterol Breath Actuated Inhaler (BAI) and Ultibro in Subjects With Fixed Airflow Obstruction and Elevated EosinophilsTerminatedNCT02693769Phase 2/3
• Cross-over Study in Volunteers to Compare the Pharmacokinetics of Tiotropium Delivered From Test and Reference ProductsCompletedNCT02676297Phase 1
• Fesoterodine for Amelioration of Autonomic Dysreflexia (AD) Following Spinal Cord Injury (SCI)CompletedNCT02676154Phase 2
• Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic SurgeryCompletedNCT02676011Phase 2
• Magnesium Sulfate Effects on Onset and Duration of Low Dose Rocuronium in Patients Undergoing Laparoscopic CholecystectomyStatus unknownNCT02669368Phase 2
• Reproducibility Study of OABSS and Its Response to TreatmentCompletedNCT02667470Phase 4
• The Neuromuscular Effect of Rocuronium in PatientStatus unknownNCT02657187Not applicable
• EC905 Pharmacokinetic Profile StudyCompletedNCT02634489Phase 1
• The Onset Time of Rocuronium in Emergency and Elective SurgeryStatus unknownNCT02634255Phase 3
• Effect of the Motilin Receptor Agonist, Erythromycin, on Hunger and Food Intake; Study of Role of Cholinergic PathwaysCompletedNCT02633579Not applicable
• Comparison of the Pharmacokinetics of Tiotropium Delivered From Test Inhaler Products With Two Reference ProductsCompletedNCT02627625Phase 1
• Duration of Long Acting Muscarinic Antagonist (LAMA) Bronchoprotection Against Methacholine ChallengeCompletedNCT02622243Phase 4
• Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal AnesthesiaCompletedNCT02622126Phase 2
• Extension Study of Fesoterodine for Overactive Bladder Syndrome in Children.CompletedNCT02614482Phase 3
• Clozapine-induced Hypersalivation - Feasibility TrialCompletedNCT02613494Phase 1/2
• Compare of Surgical Condition and Complications With Moderate and Deep NM BlockStatus unknownNCT02601508Not applicable
• the Indications and Clinical Efficacy of Pelvic Organ Prolapse SurgeryStatus unknownNCT02599311Phase 3
• 24hr Effects of Tiotropium Bromide in TetraplegiaCompletedNCT02586649Phase 2
• Evaluation of EEG With Respect to the Change of Depth of Anesthesia During General AnesthesiaStatus unknownNCT02586441Phase 4
• Buscopan Versus Acetaminophen for Acute Abdominal Pain in ChildrenCompletedNCT02582307Phase 3
• Pharmacokinetics of TD-4208 in Patients With Moderate Hepatic ImpairmentCompletedNCT02581592Phase 1
• Pharmacokinetics of TD-4208 in Patients With Severe Renal ImpairmentCompletedNCT02578082Phase 1
• Spasmolytic in Upper Gastrointestinal EndoscopyCompletedNCT02576340Phase 4
• Neuromuscular Block and Anesthetic Depth MonitoringCompletedNCT02575443Not applicable
• Ultibro® Versus Spiriva® Alone to Reduce Exertional Dyspnea in Patients With Moderate to Severe COPDCompletedNCT02567214Phase 4
• Hyoscine ButylBromide for Intrapartum AnalgesiaStatus unknownNCT02557087Phase 2

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