Cholinergic Antagonists: all 1,354 studies that test it
Page 1 of 14. Open to participants first (141), then studies with results posted, then the rest; newest registration first within each.
- Effect of Neuromuscular Blocking Agent Use on Video Laryngeal Mask Airway InsertionNot yet recruitingNCT07894029Phase 4
- Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial FibrillationRecruitingNCT07877519Not applicable
- Early Intervention for High Risk Premyopic ChildrenNot yet recruitingNCT07863713Phase 2
- Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye DropsNot yet recruitingNCT07846787Not applicable
- Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular CancerNot yet recruitingNCT07836712Phase 2
- Effect of Neuromuscular Blockade on Video Laryngeal Mask Airway VentilationNot yet recruitingNCT07828977Phase 4
- PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled TiotropiumNot yet recruitingNCT07827859Phase 4
- Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With EndometriosisNot yet recruitingNCT07821320Phase 2
- Low-Dose Atropine Eye Drops for Excessive Tearing (Epiphora)RecruitingNCT07816224Phase 2
- Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for CholedocholithiasisRecruitingNCT07814976Not applicable
- Comparison of Benzhexol and Procyclidine for Tremor in Tremor-Predominant Parkinson's DiseaseRecruitingNCT07810296Not applicable
- Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL-2)RecruitingNCT07800572Phase 2
- Pharmacokinetics of Huperzine A Oral Solution in Healthy ParticipantsNot yet recruitingNCT07784335Phase 1
- Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)Not yet recruitingNCT07721922Phase 4
- Relapse Prevention Trial Evaluating KarXT Treatment in SchizophreniaRecruitingNCT07686263Phase 3
- Effects of Anisodamine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657702Not applicable
- Desloratadine as Adjunct Therapy for Rheumatoid ArthritisRecruitingNCT07632872Phase 2
- Melatonin and Solifenacin for Double-J Ureteral Stent SymptomsRecruitingNCT07617922Phase 2
- A Dose-Finding Study of Amogammadex Sodium for Reversing Vecuronium and Rocuronium-Induced Neuromuscular BlockadeNot yet recruitingNCT07595393Phase 2
- Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical TrialRecruitingNCT07567040Phase 3
- Effect of Roflumilast and Desloratadine as Add-On Therapy in Patients With Rheumatoid ArthritisRecruitingNCT07566351Phase 2
- 0.01% and 0.025% Atropine Eye Drops Combined Auricular Acupoint Stimulation on Myopia Control and Corneal Endothelium ChangeEnrolling by invitationNCT07537166Not applicable
- Comparative Study Between Different Additives to Lidocaine 2٪ for Peribulbar Block in Vitreoretinal SurgeryNot yet recruitingNCT07519694Not applicable
- Effect of Neuromuscular Block Depth on Driving Pressure and Postoperative Respiratory Events in Abdominal SurgeriesNot yet recruitingNCT07464288Not applicable
- The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control GroupRecruitingNCT07456488Phase 2
- PROTECT-Study: Prospective Research on Optimizing Atropine Concentration Escalation for Children's Myopia PreventionNot yet recruitingNCT07449247Phase 1/2
- APPRAISE: Assessment of Pain and Posterior Synechiae Reduction With Atropine, an Investigation of Post-Surgical EyesRecruitingNCT07434635Phase 4
- Representation of Spatiotemporal Information in Human Episodic Memory and NavigationEnrolling by invitationNCT07423923Early Phase 1
- A PET/MRI Study of Cobenfy on Dopamine Transmission in SchizophreniaRecruitingNCT07423546Phase 1/2
- Effect of Ipratropium Bromide on EILONot yet recruitingNCT07394036Phase 2
- Study of Sacituzumab Govitecan With Atropine to Improve Tolerability in Advanced TNBC and HR+/HER2- Breast CancerNot yet recruitingNCT07367178Phase 2
- Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation SurgeryNot yet recruitingNCT07364370Not applicable
- Desloratadine in Patients With Ulcerative ColitisRecruitingNCT07333716Phase 2
- Atropine in the Treatment of Myopia Study in MalaysiaRecruitingNCT07329777Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)RecruitingNCT07288567Phase 3
- A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum DisorderNot yet recruitingNCT07285798Phase 3
- A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With AutismNot yet recruitingNCT07284745Phase 3
- A Clinical Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Capsules for Preoperative Preparation in Painless Gastrointestinal Endoscopy ProceduresNot yet recruitingNCT07271303Not applicable
- A Study to Evaluate the Effect of KarXT on Urological SafetyRecruitingNCT07221877Phase 4
- A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult ParticipantsRecruitingNCT07204418Phase 1
- Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney DiseaseRecruitingNCT07203287Phase 4
- Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNERecruitingNCT07199894Phase 3
- 129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of ExacerbationRecruitingNCT07192016Phase 4
- Early-Onset Myopia Intervention ProjectRecruitingNCT07176949Not applicable
- Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic CenterNot yet recruitingNCT07164092Phase 2/3
- Scalp Block Versus General Anesthesia in Patients Undergoing Evacuation of Subdural Hematoma Via Burr HoleRecruitingNCT07143799Not applicable
- A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or LamotrigineRecruitingNCT07140913Phase 3
- Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting BronchodilatorsRecruitingNCT07133880Phase 4
- The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled TrialNot yet recruitingNCT07114640Phase 3
- Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism PainRecruitingNCT07109882Phase 4
- A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia ControlRecruitingNCT07095894Phase 3
- A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With SchizophreniaNot yet recruitingNCT07084831Phase 3
- A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and HyperinflationRecruitingNCT07073950Phase 4
- A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, Explore the Effect of Food After Multiple Doses of Selected Prototypes, and Evaluate Alternative Formulations of KarX and KarXT Following Single and Multiple Ascending DosesRecruitingNCT07063342Phase 1
- A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXTRecruitingNCT07061288Phase 1
- Reversal of Pipecuronium-induced Neuromuscular Blockade With Sugammadex During Sevoflurane AnesthesiaNot yet recruitingNCT07044193Phase 4
- Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)RecruitingNCT07028827Phase 3
- Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder DysfunctionRecruitingNCT07027020Phase 3
- A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's DiseaseRecruitingNCT07011745Phase 3
- A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)RecruitingNCT07011732Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseRecruitingNCT06976216Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)RecruitingNCT06976203Phase 3
- Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled TrialRecruitingNCT06966778Not applicable
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)RecruitingNCT06951711Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderRecruitingNCT06951698Phase 3
- A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)RecruitingNCT06947941Phase 3
- A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)RecruitingNCT06937229Phase 3
- A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)RecruitingNCT06929273Phase 3
- An 8-week Open-label Study of an Accelerated and Slower Switching to Xanomeline/Trospium Following Atypical Antipsychotic Treatment in Participants With SchizophreniaNot yet recruitingNCT06924255Phase 4
- An Open-Label Study to Evaluate the Efficacy and Tolerability of Xanomeline/Trospium In First Episode/Early Phase Schizophrenia PatientsNot yet recruitingNCT06923891Phase 4
- A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With SchizophreniaRecruitingNCT06882785Phase 3
- Study of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related SymptomsRecruitingNCT06803030Phase 3
- Evaluating the Efficacy of the Combination of Multi-zonal Contact Lens and Atropine for Controlling Myopia ProgressionNot yet recruitingNCT06765603Phase 2
- Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for BronchoscopyNot yet recruitingNCT06709066Not applicable
- The Effectiveness and Safety of Two Low-concentration Atropine Sulfate Eye Drops (0.01%/0.02%) for Delaying the Pediatric Myopia ProgressionRecruitingNCT06708156Phase 3
- The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)RecruitingNCT06707532Not applicable
- The Study of Ginkgo Leaf Dropping Pills and Huperzine A Injection Combined With Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain InjuryRecruitingNCT06704334Phase 4
- Carvedilol and Alverine in Portal HypertensionNot yet recruitingNCT06696248Phase 2/3
- Deep Neuromuscular Blockade on Postoperative PainRecruitingNCT06679569Not applicable
- Evaluating the Impact of Single Dose Tiotropium on Allergen-induced Early Asthmatic ResponseNot yet recruitingNCT06679465Phase 4
- A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)RecruitingNCT06585787Phase 3
- Effect of the Inhaled Triple Therapies Over the Small Airway in Biomass ExposureRecruitingNCT06571942Phase 4
- Continuation Protocol for Obstructive Sleep Apnea (OSA)Enrolling by invitationNCT06566820Phase 3
- Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral PalsyRecruitingNCT06554288Phase 1
- Deep Versus Moderate Neuromuscular Blockade in Bariatric SurgeryNot yet recruitingNCT06553066Not applicable
- Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)RecruitingNCT06551246Phase 3
- Effect of Different Depths of Neuromuscular Blockade on Respiratory Mechanics in Patients With Moderate-severe Acute Respiratory Distress SyndromeRecruitingNCT06514209Not applicable
- Efficacy of Solifenacin or Mirabegron With Local Estrogen Versus Combination Pharmacotherapy for Overactive BladderRecruitingNCT06479720Phase 4
- The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver CirrhosisNot yet recruitingNCT06470386Phase 2/3
- Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle RelaxantsRecruitingNCT06399445Phase 4
- The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled TrialNot yet recruitingNCT06395064Not applicable
- A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible BronchoscopyNot yet recruitingNCT06376942Phase 2/3
- Accelerating TMS for Cervical DystoniaEnrolling by invitationNCT06328114Phase 2
- A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary DiseaseRecruitingNCT06283966Phase 3
- Low Dose Atropine Eye Drops in Myopic Egyptian ChildrenNot yet recruitingNCT06265454Phase 2
- A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALSRecruitingNCT06249867Phase 2
- Over-the-Counter Antihistamines & Heat StressRecruitingNCT06217367Phase 4
- The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled TrialRecruitingNCT06203405Not applicable
- Efficacy of Combined Pharmacotherapy Versus Solifenacin With Vaginal Estrogen Cream for Women With Detrusor OveractivityRecruitingNCT06197295Phase 4
- A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)RecruitingNCT06126224Phase 3