Cholinergic Antagonists: all 1,354 studies that test it

Page 8 of 14. Open to participants first (141), then studies with results posted, then the rest; newest registration first within each.

• The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood FlowTerminatedNCT04777383Not applicable
• The Effect and Safety of Different Doses of Atropine on Myopic Progression of Highly Myopic Children: Multi-centered Randomized Clinical TrialCompletedNCT04699357Not applicable
• The Food Effect on Pharmacokinetics of DA-8010 After a Single Administration of DA-8010 2.5 mg or 5 mg in Healthy SubjectsCompletedNCT04686825Phase 1
• Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine ButylbromideCompletedNCT04682860Phase 4
• Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCICompletedNCT04671030Phase 1
• Tiotropium Efficacy Against Allergen Induced Early Asthmatic ResponsesCompletedNCT04648813Phase 4
• Pharmacological Enhancement for Nocturnal Incontinence in Orthotopic Bladder SubstituteCompletedNCT04635566Not applicable
• Evaluation of Meclizine Orodispersible Tablet Pharmacokinetic in Human VolunteersStatus unknownNCT04564144Phase 1/2
• The Off Label Use of Glycopyrrolate in the Adults Intensive Care Unit.Status unknownNCT04554589Phase 1
• Effect of Perioperative Bronchodilator in COPD Patients Undergoing Lung Cancer SurgeryActive, not recruitingNCT04536675Phase 3
• Effect of Dual Bronchodilation With Umeclidinium/Vilanterol on Patients With COPD, Hyperinflation and Heart FailureCompletedNCT04522596Phase 4
• Three Treatment of Chronic Obstructive Pulmonary Disease PatientsCompletedNCT04520230Phase 4
• A Comparison of Rocuronium 0.3 mg/kg, and 0.9 mg/kg for Induction of Anesthesia in Elderly Patients.CompletedNCT04512313Not applicable
• Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic PatientsTerminatedNCT04509336Not applicable
• Clinical Study of Huperzine A in the Treatment of Patients With Hypertensive Cerebral HemorrhageStatus unknownNCT04509323Phase 4
• Low Dose Tadalafil for Treatment of Female OAB Syndrome: Short Term Follow up.CompletedNCT04500860Phase 1
• Meclizine Plasma Levels in Responders and Non-respondersStatus unknownNCT04482985Phase 4
• Efficacy of Biofeedback PFMT and Medication in Women With Overactive BladderCompletedNCT04477265Not applicable
• Efficacy of Li-SWT on Persistent Storage Symptoms After Transurethral Surgery for BPOCompletedNCT04437108Not applicable
• Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal AnaesthesiaCompletedNCT04401345Phase 4
• Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.CompletedNCT04399148Not applicable
• The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALSStatus unknownNCT04391361Phase 2
• The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among PrimigravidaeCompletedNCT04349722Phase 4
• Onabotulinum Dose Comparison in Chronic Migraine Superior to 100 Units?TerminatedNCT04349176Phase 3
• Efficacy of Mirabegron Versus Tamsulosin Versus Solifenacin for Treatment of Ureteral Stents-Related SymptomsStatus unknownNCT04325880Phase 3
• A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPDCompletedNCT04320342Phase 3
• A Comparison of Rocuronium 0.6 mg/kg and Remifentanil 2 µg/kg in Elderly Patients Over 80 YearsCompletedNCT04287426Phase 4
• Nasal Gel Under Military Operational Conditions for the Prevention of Nausea Associated With Motion SicknessStatus unknownNCT04272255Phase 3
• Clinical Study to Assess the Efficacy and Safety of AT-5214 in the Treatment of Subjects With Palmar HyperhidrosisStatus unknownNCT04263623Phase 2
• Continuous Infusion and Bolus Doses of Rocuronium During Lumbal Discectomy, Muscle Strength and Patient RecoveryCompletedNCT04236050Not applicable
• DPI 386 Nasal Gel for the Prevention of Nausea Associated With Motion SicknessTerminatedNCT04219982Phase 2/3
• Nasal Gel for the Prevention and Treatment of Nausea Associated With Motion SicknessCompletedNCT04184115Phase 3
• Topical 0.01% Atropine for the Control of Fast Progressing MyopiaTerminatedNCT04173780Phase 2/3
• Methacholine, Long-acting M-cholinolytic and beta2-agonist on the Activity of Beta-receptors in Healthy VolunteersStatus unknownNCT04137029Not applicable
• Deep NMB in Ambulatory Gynecological LaparoscopyCompletedNCT04105764Phase 4
• Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean SectionCompletedNCT04069078Phase 4
• Compare Sudden Stopping and Weaning of Anticholinergics in Recurrence of OAB SymptomsCompletedNCT04064619Not applicable
• Anti-inflammatory Effects of Tiotropium in Patients with Stable COPDCompletedNCT04061161Phase 4
• Performance of Rigid Gas Permeable (RGP) Scleral Contact Lenses With a Passive Artificial IrisTerminatedNCT04040790Not applicable
• Serum Tryptase Concentration During General Anaesthesia With RocuroniumCompletedNCT04035707Not applicable
• The PATHFINDER Study: A Feasibility TrialCompletedNCT04016740Early Phase 1
• A 24-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Peripheral NeuropathyCompletedNCT04005287Phase 2
• Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture HeadacheCompletedNCT03997006Phase 4
• Prevention and Treatment of Nausea Associated With Motion Sickness in Senior SubjectsCompletedNCT03988530Phase 3
• The Prevention and Treatment of Nausea Associated With Motion SicknessCompletedNCT03986905Phase 3
• Atropine or Ephedrine Pretreatment for Preventing Bradycardia in Elderly PatientsCompletedNCT03984526Phase 4
• BUSCLAB - Buscopan to Prevent Slow Progress in LaborCompletedNCT03961165Phase 3
• Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness StudyWithdrawnNCT03949842Phase 4
• Atropine for Children and Adolescent Myopia Progression StudyStatus unknownNCT03949101Phase 4
• Effect of Charcoal on Gastrointestinal Absorption of TiotropiumCompletedNCT03945344Phase 1
• Microdosed Atropine 0.1% and 0.01% Ophthalmic Solutions for Reduction of Pediatric Myopia ProgressionTerminatedNCT03942419Phase 3
• Intrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CSCompletedNCT03932578Phase 4
• Study of the Safety and Efficacy of DPI-386 Nasal Gel on Ocean-Going VesselsStatus unknownNCT03920644Phase 3
• Mecamylamine for Autonomic Dysreflexia ProphylaxisStatus unknownNCT03914677Phase 4
• The Effect of Deep Neuromuscular Blockade on Requirement of Intravenous Anesthetic AgentCompletedNCT03890406Not applicable
• Deep vs Moderate Neuromuscular Blockade in Day Case Laparoscopic Cholecystectomy.CompletedNCT03881423Phase 4
• Efficacy of Oxybutynin in Paediatric CystitisCompletedNCT03877289Phase 4
• Scopolamine in Healthy VolunteersStatus unknownNCT03874130Phase 1
• Effect of Interferential Electrical Stimulation on Pain Perception and Disability Level on Interstitial CystitisCompletedNCT03844581Not applicable
• Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence TomographyCompletedNCT03842839Not applicable
• Short Term Refractive and Ocular Parameter Changes After Topical AtropineCompletedNCT03839888Not applicable
• Regional Anesthesia Versus General AnesthesiaCompletedNCT03830086Not applicable
• Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive BladderCompletedNCT03817931Phase 4
• Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in ChildrenCompletedNCT03795259Not applicable
• The Use of Sugammadex in the Critically IllStatus unknownNCT03791801Not applicable
• Ipratropium Bromide Spray as Treatment for Sialorrhea in ChildrenStatus unknownNCT03747536Phase 2
• Effectiveness of Antitussives, Anticholinergics and Honey Versus Usual Care in Adults With Acute Bronchitis.CompletedNCT03738917Phase 4
• Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:SuspendedNCT03709992Not applicable
• Effects of Low Concentration Atropine on Pupillary Size and Accommodative AmplitudeCompletedNCT03699423Phase 1
• Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye DropsCompletedNCT03690414Phase 1
• Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United KingdomActive, not recruitingNCT03690089Phase 2
• Measurement of the Skin Sympathetic Nerve ActivityCompletedNCT03658057Not applicable
• Partial Neuromuscular Blockade for Lung Protective Mechanical VentilationStatus unknownNCT03646266Phase 4
• Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in PhacoemulsificationStatus unknownNCT03638726Phase 4
• Comparison of Solifenacin and Mirabegron in Treatment of Overactive Bladder Symptoms in Men After TURPStatus unknownNCT03632772Phase 2
• Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With ClopidogrelStatus unknownNCT03596060Not applicable
• Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb SurgeriesStatus unknownNCT03580889Phase 4
• Bethanechol Prior to Pancreatic SurgeryCompletedNCT03572283Early Phase 1
• A Therapeutic Exploratory Clinical Study of DA-8010 in Patients With Overactive BladderCompletedNCT03566134Phase 2
• The Effects of Low Dose Atropine on Choroidal ThicknessCompletedNCT03544827Phase 4
• Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn SurgeryCompletedNCT03513406Phase 3
• Efficacy of Hyoscine-n-butylbromide in Catheter-related Bladder Discomfort After Elective Cesarean Section.CompletedNCT03513250Not applicable
• Atropine 0.01% Eye Drops in Myopia StudyStatus unknownNCT03508817Early Phase 1
• Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD.CompletedNCT03499743Not applicable
• Acute Bronchodilator Effect of Inhaled Albuterol Sulfate and Ipratropium Bromide in Patients With Stable COPDCompletedNCT03480997Phase 1
• Hyoscine Butylbromide Effect on Duration of LaborCompletedNCT03441217Not applicable
• Effect Of Intravenous Hyoscine -N-Butyl Bromide In Management Of Prolonged Labor In NulliparousCompletedNCT03430362Not applicable
• Effects of Dual Bronchodilator Treatment on Cardiopulmonary Interactions in COPDCompletedNCT03425617Phase 4
• Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar HyperhidrosisCompletedNCT03404570Phase 2
• Pharmacokinetic Study Comparing Tiotropium Easyhaler and Spiriva HandihalerCompletedNCT03400241Phase 1
• Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General AnesthesiaStatus unknownNCT03391700Not applicable
• Intrathecal Atropine to Prevent Postoperative Nausea and VomitingCompletedNCT03387956Not applicable
• Effectiveness of Fluticasone Furoate/ Umeclidinium/ Vilanterol (FF/UMEC/VI) Using the Connected Inhaler System (CIS) as Compared With Fluticasone Proprionate/ Salmeterol (FP/SAL) Plus Tiotropium (TIO) in Inadequately Controlled AsthmaWithdrawnNCT03376932Phase 3
• Evaluation of Atracurium-vecuronium Combination in Laparosocpic SurgeryStatus unknownNCT03371953Phase 4
• Effect of NMBA on Surgical Conditions in THRWithdrawnNCT03369782Phase 4
• Utilizing Wearable Device to Observe the Clinical Response of COPD Patients Treated With Combined Bronchodilator and Home-based Pulmonary Rehabilitation ProgramStatus unknownNCT03364829Phase 4
• A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine AdministrationCompletedNCT03359655Not applicable
• Radial Extracorporeal Shock Wave Therapy for Chronic Non-specific Low Back PainCompletedNCT03337607Not applicable
• The Study of Pharmacokinetics and Pharmacodynamics of CisatracuriumCompletedNCT03337373Phase 4
• Combined Use of Low-dose Sugammadex Plus Neostigmine Administered for Reversal of RocuroniumStatus unknownNCT03328312Early Phase 1

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