Cholinergic Antagonists: all 1,354 studies that test it

Page 3 of 14. Open to participants first (141), then studies with results posted, then the rest; newest registration first within each.

• Side Effects of Atropine (SEA) StudyCompletedNCT03593044Phase 1/2Results posted
• Efficacy and Safety Evaluating Study to Compare Uritos® (Imidafenacin) and Urotol® (Tolterodine) for Treatment of Overactive Bladder.CompletedNCT03575702Phase 3Results posted
• A 42-day Parallel Group Safety Study of Revefenacin and Formoterol, Administered in Sequence and as a Combination, in Participants With COPDCompletedNCT03573817Phase 3Results posted
• Opioid-Free Shoulder ArthroplastyCompletedNCT03540030Phase 4Results posted
• Efficacy and Safety of Org 25969 Administered After Zemuron® (MK-8616-042)CompletedNCT03519867Phase 2Results posted
• A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC /VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03478696Phase 4Results posted
• A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03478683Phase 4Results posted
• A Comparative Study Between Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy Versus Tiotropium Monotherapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03474081Phase 4Results posted
• INTREPID: Investigation of TRELEGY Effectiveness: Usual Practice DesignCompletedNCT03467425Phase 4Results posted
• Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve GastrectomyCompletedNCT03435003Phase 4Results posted
• The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major DepressionCompletedNCT03386448Phase 4Results posted
• Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression RateCompletedNCT03374306Not applicableResults posted
• Patient-controlled Sedation With Propofol Versus Combined Sedation During BronchoscopyCompletedNCT03357393Not applicableResults posted
• Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)CompletedNCT03346057Phase 4Results posted
• Low-Dose Atropine for Treatment of MyopiaCompletedNCT03334253Phase 3Results posted
• A Phase I, Open-Label, Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide in Healthy Chinese ParticipantsCompletedNCT03276052Phase 1Results posted
• Study to Assess the Safety and Efficacy of PT010, PT003, and PT009 in Japanese Subjects With COPD Compared With Symbicort® Turbohaler®CompletedNCT03262012Phase 3Results posted
• The ENERGITO® 2 Study Compares 2 Inhaled Medicines for Chronic Obstructive Pulmonary Disease (COPD). One Medicine is a Combination of Tiotropium and Olodaterol (Stiolto®) Taken Using the Respimat® Inhaler and the Other Medicine is a Combination of Fluticasone and Salmeterol Taken Using the DiskusCompletedNCT03240575Phase 4Results posted
• Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)TerminatedNCT03219866Phase 4Results posted
• Does Deep Neuromuscular Blockade Improve Operating Conditions During Total Hip Replacements?CompletedNCT03219294Phase 4Results posted
• Effect of Heat on Oxybutynin Release and Absorption From Oxybutynin ProductsCompletedNCT03205605Early Phase 1Results posted
• Efficacy of Intermittent Tiotropium in Early Childhood WheezingTerminatedNCT03199976Phase 4Results posted
• Efficacy and Safety of Glycopyrronium/Formoterol Fumarate Fixed-dose Combination Relative to Umeclidinium/Vilanterol Fixed-dose Combination Over 24 Weeks in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary DiseaseCompletedNCT03162055Phase 3Results posted
• Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson DiseaseCompletedNCT03149809Phase 3Results posted
• Bronchodilator Effects and Safety of Glycopyrronium Bromide (25 ug and 50 ug o.d.) in AsthmaCompletedNCT03137784Phase 2/3Results posted
• Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03118765Phase 2Results posted
• Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle RelaxantCompletedNCT03116997Phase 3Results posted
• Use of Sugammadex for Reversal of Paralysis in MicrolaryngoscopyCompletedNCT03111121Phase 4Results posted
• Revefenacin Peak Inspiratory Flow Rate (PIFR) Study in COPDCompletedNCT03095456Phase 3Results posted
• A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary DiseaseCompletedNCT03084796Phase 2Results posted
• Effects of TD-4208 on FEV1 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03064113Phase 2Results posted
• Comparison of Obturator Nerve Blockade and Neuromuscular BlockadeCompletedNCT03063255Phase 4Results posted
• Cardiovascular Function in COPD PatientsCompletedNCT03055988Phase 4Results posted
• Neuromuscular Blockade During Transurethral Resection of Bladder CancerCompletedNCT03039543Phase 4Results posted
• Scopolamine Patch Pharmacokinetics in Healthy AdultsCompletedNCT03029650Phase 4Results posted
• The Effects of RPL554 in Addition to Tiotropium in COPD PatientsCompletedNCT03028142Phase 2Results posted
• A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary HyperhidrosisCompletedNCT03024255Phase 2Results posted
• Study to Assess Efficacy and Safety of Aclidinium Bromide and Aclidinium Bromide/Formoterol Fumarate in Stabile COPD PatientsCompletedNCT03022097Phase 3Results posted
• Phase IIb Study of Umeclidinium (UMEC) Bromide Versus Placebo in Subjects With AsthmaCompletedNCT03012061Phase 2Results posted
• Bioavailability of Tiotropium + Olodaterol Fixed-dose Combination (5 μg/ 5 μg) in Chinese COPD PatientsCompletedNCT02969317Phase 1Results posted
• Oxybutynin Chloride in Managing Hot FlashesCompletedNCT02961790Phase 3Results posted
• Scopolamine Patch and Acupressure Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean SectionCompletedNCT02960113Phase 4Results posted
• A Study to Assess the Effects of PT001 and PT005 MDI on Specific Image Based Parameters in Subjects With Moderate to Severe COPDCompletedNCT02937584Phase 3Results posted
• Atropine in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)CompletedNCT02927223Not applicableResults posted
• Optimal Method for Mydriasis in Cataract SurgeryTerminatedNCT02909140Not applicableResults posted
• Minimizing Nausea and Vomiting During Spinals for CSTerminatedNCT02872935Phase 4Results posted
• RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials CooperativeCompletedNCT02867761Phase 3Results posted
• AMPLIFY - D6571C00001 Duaklir USA Phase III StudyCompletedNCT02796677Phase 3Results posted
• Comparative Study of Fluticasone Furoate(FF)/Umeclidinium Bromide (UMEC)/ Vilanterol (VI) Closed Therapy Versus FF/VI Plus UMEC Open Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02729051Phase 3Results posted
• Surgical Conditions During Laparoscopic Bariatric SurgeryCompletedNCT02703909Phase 4Results posted
• Study to Evaluate the Treatment Effect of PT003 on Cardiovascular Hemodynamics in Subjects With Moderate to Severe COPDTerminatedNCT02685293Phase 3Results posted
• A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar HyperhidrosisCompletedNCT02682238Phase 2Results posted
• A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis SubjectsCompletedNCT02673619Phase 2Results posted
• Orphenadrine and Methocarbamol for LBPCompletedNCT02665286Phase 4Results posted
• A Pilot Study Exploring the Efficacy and Safety of Topical Oxybutynin 3% Gel for Primary Focal Hyperhidrosis in Adolescents and Young AdultsCompletedNCT02633371Not applicableResults posted
• Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted
• Dose-Finding Study of Batefenterol (GSK961081) Via Dry Powder Inhaler in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02570165Phase 2Results posted
• Pharmacokinetic, Safety, Tolerability, and Clinical Effect of Topical Umeclidinium in Primary Axillary HyperhidrosisCompletedNCT02563899Phase 2Results posted
• Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese PatientsCompletedNCT02553629Phase 4Results posted
• A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's TypeCompletedNCT02549196Phase 2Results posted
• Study to Assess the Safety and Tolerability of PT010, PT009 and PT003 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary DiseaseCompletedNCT02536508Phase 3Results posted
• A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02518139Phase 3Results posted
• Determine the Bioequivalence of Two Formulations of Hyoscine Butylbromide.CompletedNCT02516098Phase 1Results posted
• Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02512510Phase 3Results posted
• Study to Determine the Amount of Glycopyrrolate Absorbed in the Lungs After Taking the Medicine With a eFlow Nebulizer and Seebri® Breezhaler® With and Without Activated Charcoal in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).CompletedNCT02512302Phase 1Results posted
• Reevaluation Of Systemic Early Neuromuscular BlockadeCompletedNCT02509078Phase 3Results posted
• A Randomized, Double-Blind, Parallel-Group, 24-Week, Chronic-Dosing, Multi-Center Study to Assess the Efficacy and Safety of PT010, PT003, and PT009 Compared With Symbicort® Turbuhaler® (Kronos)CompletedNCT02497001Phase 3Results posted
• Efficacy and Safety Study of Indacaterol Maleate/Glycopyrronium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients.CompletedNCT02487498Phase 3Results posted
• Efficacy and Safety Study of QVA149 in COPD PatientsCompletedNCT02487446Phase 3Results posted
• Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?CompletedNCT02484651Phase 4Results posted
• Optimal Inspiratory Pressure for Facemask Pressure-controlled Ventilation in ChildrenCompletedNCT02471521Not applicableResults posted
• Study to Assess the Efficacy and Safety of PT010 Relative to PT003 and PT009 in Subjects With Moderate to Very Severe COPD (Ethos)CompletedNCT02465567Phase 3Results posted
• Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02459080Phase 3Results posted
• Effect of Aclidinium/Formoterol on Lung Hyperinflation, Exercise Capacity and Physical Activity in Moderate to Severe COPD PatientsCompletedNCT02424344Phase 4Results posted
• Efficacy of Open Label Placebo in Children With FGIDsCompletedNCT02389998Not applicableResults posted
• BENEFITS OF ACLIDINIUM BROMIDE IN THE RELIEF OF COPD SYMPTOMS INCLUDING COUGHCompletedNCT02375724Phase 4Results posted
• A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPDCompletedNCT02371629Phase 4Results posted
• 24-hour Lung Function in Subjects With Moderate to Very Severe COPD After Treatment With PT003 and Placebo MDICompletedNCT02347085Phase 3Results posted
• 24-hour Lung Function in Subjects With Moderate to Very Severe COPD After Treatment With PT003, Open-Label Spiriva® Respimat® as an Active Control, and PlaceboCompletedNCT02347072Phase 3Results posted
• Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPDCompletedNCT02343458Phase 3Results posted
• A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary HyperhidrosisCompletedNCT02336503Phase 2Results posted
• Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen PlanusCompletedNCT02329600Phase 3Results posted
• Efficacy and Safety Study of Desloratadine (MK-4117) in Japanese Participants With Seasonal Allergic Rhinitis (MK-4117-204)CompletedNCT02320396Phase 3Results posted
• Efficacy of LAMA Added to ICS in Treatment of Asthma (ELITRA)CompletedNCT02296411Phase 2Results posted
• Neuromuscular Blockade for Post-Cardiac Arrest CareCompletedNCT02260258Phase 2Results posted
• Optimizing Surgical Conditions During Laparoscopic Herniotomy With Deep Neuromuscular BlockadeCompletedNCT02247466Phase 4Results posted
• Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Tablets for the Treatment of Occasional or Recurrent Episodes of Gastric or Intestinal Spasm-like Pain or DiscomfortCompletedNCT02242305Phase 3Results posted
• A 12-week Study to Evaluate the Efficacy and Safety of Umeclidinium 62.5 Microgram (mcg) Compared With Glycopyrronium 44 mcg in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02236611Phase 4Results posted
• Pharmacokinetics and Safety of BI 1744 CL Plus Tiotropium Bromide in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02231177Phase 1Results posted
• A 12-week Study to Evaluate the Efficacy and Safety of Umeclidinium Compared With Tiotropium in Subjects With Chronic Obstructive Pulmonary DiseaseCompletedNCT02207829Phase 3Results posted
• Prospective Cohort Study for the Real - Life Effectiveness Evaluation of GlycOpyrronium With IndacatERol Combination in the Management of COPD in Canada (POWER Study)CompletedNCT02202616Phase 4Results posted
• Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory MechanicsCompletedNCT02185339Phase 4Results posted
• A 24 Week Efficacy Study of Inhaled Umeclidinium (UMEC) in Patients of Chronic Obstructive Pulmonary Disease (COPD) Using a Novel Dry Powder Inhaler (NDPI)CompletedNCT02184611Phase 3Results posted
• Comparison of Combination Therapy vs Single Agent Therapy for Treatment of Urge Incontinence.TerminatedNCT02176642Phase 4Results posted
• Evaluation of Umeclidinium Bromide in Combination With Fluticasone Furoate in COPD Subjects With an Asthmatic ComponentCompletedNCT02164539Phase 2Results posted
• A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02164513Phase 3Results posted
• Pharmacokinetic and Efficacy Profile Intranasal Scopolamine SprayTerminatedNCT02155309Phase 2/3Results posted
• A Double-blind, Placebo-controlled, Crossover Study to Assess the Effect of Aclidinium Bromide 400 μg Bid on COPD Symptoms and Sleep Quality After 3 Weeks of Treatment in Patients With Stable Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02153489Phase 4Results posted
• A Study to Evaluate Tolerability and Participants Preference Between Mirabegron and Tolterodine Extended Release (ER) in Participants With Overactive Bladder (OAB)CompletedNCT02138747Phase 4Results posted
• Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary HyperhidrosisCompletedNCT02129660Phase 2Results posted

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