Ayahuasca clinical trials
How each study uses ayahuasca is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the ayahuasca studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
10 studies that test it; most in 2025 (3)
| Year | Studies |
|---|---|
| 2014 | 1 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 3 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 0 · Other 10
University of Sao Paulo (8) · Universidade Federal do Rio Grande do Norte (1) · Advanced Integrative Medical Science Institute (1)
Often tested with
Tested in the same studies.
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test ayahuasca.
- Aug 2027Effects of a Sigle Dose of Ayahuasca in Patients With Psychogenic Non-epileptic Seizures: an Open Label Clinical TrialPhase 1/2 · University of Sao Paulo
Studies
Open first, then newest update. How each study uses ayahuasca is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 10
- Acute Effects of a Single Dose of Ayahuasca on Cerebral Metabolism in Healthy Volunteers: a PET StudyEnrolling by invitationEarly Phase 1University of Sao PauloNCT07893912Written as Ayahuasca
- Effects of a Sigle Dose of Ayahuasca in Patients With Psychogenic Non-epileptic Seizures: an Open Label Clinical TrialRecruitingPhase 1/2University of Sao PauloNCT07747324Written as Ayahuasca
- Ayahuasca, Esketamine and PTSDRecruitingPhase 2University of Sao PauloNCT07317206Written as Ayahuasca
- Ayahuasca, Esketamine and Body Image PerceptionRecruitingNot applicableUniversity of Sao PauloNCT07317219Written as Ayahuasca
- Ayahuasca, Esketamine and Premenstrual SymptomsRecruitingNot applicableUniversity of Sao PauloNCT07317232Written as Ayahuasca
- Open-Label Dose-Ranging Study of Oral SM-001 in Healthy AdultsNot yet recruitingPhase 1Advanced Integrative Medical Science InstituteNCT05894902Written as SM-001
- Single-dose Effects of Ayahuasca Compared to Esketamine on Experimentally Induced PainCompletedEarly Phase 1University of Sao PauloNCT07910838Written as Ayahuasca
- Effects of Different Doses of Ayahuasca on Personality in Healthy VolunteersCompletedEarly Phase 1University of Sao PauloNCT07893769Written as Ayahuasca
- Ayahuasca and Esketamine for Major DepressionCompletedPhase 2University of Sao PauloNCT07212946Written as Ayahuasca
- Antidepressant Effects of Ayahuasca: a Randomized Placebo Controlled Trial in Treatment Resistant DepressionCompletedPhase 1/2Universidade Federal do Rio Grande do NorteNCT02914769Written as Ayahuasca