Drug
Avacincaptad pegol clinical trials
Also written IZERVAY and ARC1905.
- studies test it
- 11
- open now
- 0
- in phase 3
- 3
- first study started
- 2008
How studies write it
Studies that test it under each name
Studies by the year they started
11 studies that test it; most in 2015 (2)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2009 | 1 |
| 2015 | 2 |
| 2017 | 1 |
| 2018 | 2 |
| 2020 | 1 |
| 2022 | 1 |
| 2025 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 5
- Phase 3
- 3
- Phase 4
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 11 · Other 0
Ophthotech Corporation (5) · Astellas Pharma Global Development, Inc. (2) · IVERIC bio, Inc. (2) · Astellas Pharma Inc (1) · Hoffmann-La Roche (1)
Often tested with
Tested in the same studies.
Ranibizumab (1) · RO7669330 (1) · Pegcetacoplan (1) · Aflibercept (1)
Studies
Open first, then newest update. How each study uses avacincaptad pegol is read from its arms, and is right about nine times in ten.
Testing it · 11
- A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular DegenerationActive, not recruitingPhase 4Astellas Pharma IncNCT06970665Written as avacincaptad pegol
- A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)TerminatedPhase 1Hoffmann-La RocheNCT06961370Written as Izervay™
- Avacincaptad Pegol Open-Label Extension for Patients With Geographic AtrophyCompletedPhase 3Astellas Pharma Global Development, Inc.NCT05536297Written as avacincaptad pegol
- Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)CompletedPhase 2Astellas Pharma Global Development, Inc.NCT03364153Written as avacincaptad pegol
- A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)CompletedPhase 3IVERIC bio, Inc.NCT04435366Written as Avacincaptad Pegol
- Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular DegenerationCompletedPhase 2/3IVERIC bio, Inc.NCT02686658Written as Avacincaptad Pegol
- ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD)CompletedPhase 2Ophthotech CorporationNCT03362190Written as Avacincaptad Pegol
- A Study to Establish the Safety and Tolerability of Zimura™ (Anti-C5 Aptamer) in Combination With Anti-VEGF Therapy in Subjects With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV)CompletedPhase 2Ophthotech CorporationNCT02397954Written as Avacincaptad Pegol
- ARC1905 (Anti-C5 Aptamer) Given With Lucentis 0.5 mg In People With Neovascular Age-Related Macular DegenerationCompletedPhase 1Ophthotech CorporationNCT00709527Written as Avacincaptad Pegol
- A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular DegenerationCompletedPhase 1Ophthotech CorporationNCT00950638Written as Avacincaptad Pegol
- ZIMURA in Combination With Eylea in Patients With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV)WithdrawnPhase 2Ophthotech CorporationNCT03374670Written as Zimura
Given in every arm · 1 — avacincaptad pegol is usual care beside what is tested
Codes
What other systems call avacincaptad pegol · ClinicalTrials.gg INT002125
- MeSH (NLM) C000731678avacincaptad pegolOne source NLM
- UNII (FDA) TT0V5JLG5BAVACINCAPTAD PEGOLConfirmed FDA, NLM, Wikidata
- Wikidata Q121945069avacincaptad pegolConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C171668Avacincaptad PegolOne source FDA
- DrugBank DB15165One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000731678 | avacincaptad pegol | One source NLM |
| UNII (FDA) | TT0V5JLG5B | AVACINCAPTAD PEGOL | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q121945069 | avacincaptad pegol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C171668 | Avacincaptad Pegol | One source FDA |
| DrugBank | DB15165 | — | One source Wikidata |
Also registered as avacincaptad pegol sodium (UNII K86ENL12I5).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.