Aromatase inhibitors: all 608 studies that test it

Page 2 of 7. Open to participants first (88), then studies with results posted, then the rest; newest registration first within each.

• Anastrazole and Clomiphene to Evaluate Hypogonadal Symptoms and Erectile FunctionCompletedNCT03933618Phase 2Results posted
• Study to Compare the Combination of Ribociclib Plus Goserelin Acetate With Hormonal Therapy Versus Combination Chemotherapy in Premenopausal or Perimenopausal Patients With Advanced or Metastatic Breast CancerCompletedNCT03839823Phase 2Results posted
• Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast CancerCompletedNCT03774472Phase 1/2Results posted
• Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast CancerCompletedNCT03747042Phase 2Results posted
• Ribociclib and Letrozole Treatment in Ovarian CancerActive, not recruitingNCT03673124Phase 2Results posted
• Testing the Effects of Palbociclib and Fulvestrant or Letrozole for Patients 70 Years of Age of Older With Metastatic Breast CancerCompletedNCT03633331Phase 2Results posted
• Aromatase Inhibitors and Weight Loss in Severely Obese Men With HypogonadismCompletedNCT03490513Phase 4Results posted
• Ribociclib and Aromatase Inhibitor in Treating Older Participants With Hormone Receptor Positive Metastatic Breast CancerCompletedNCT03477396Phase 2Results posted
• Study of the Molecular Features of Postmenopausal Women With HR+ HER2-negative aBC on First-line Treatment With Ribociclib and Letrozole and, in Patients With a PIK3CA Mutation, on Second-line Treatment With Alpelisib Plus FulvestrantTerminatedNCT03439046Phase 3Results posted
• Exemestane in Treating Patients With Complex Atypical Hyperplasia of the Endometrium/Endometrial Intraepithelial Neoplasia or Low Grade Endometrial CancerCompletedNCT03300557Phase 2Results posted
• Pulmonary Hypertension and Anastrozole TrialCompletedNCT03229499Phase 2Results posted
• Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Node-Negative Breast CancerCompletedNCT03219476Phase 2Results posted
• Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole, Based on Prior Endocrine Therapy, in Patients With PIK3CA Mutant, HR+, HER2- Advanced Breast Cancer Who Have Progressed on or After Prior TreatmentsCompletedNCT03056755Phase 2Results posted
• Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot)CompletedNCT02959853Phase 4Results posted
• Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast CancerTerminatedNCT02907918Phase 2Results posted
• Genomic Based Assignment of Therapy in Advanced Urothelial CarcinomaCompletedNCT02788201Phase 2Results posted
• Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)Active, not recruitingNCT02764541Phase 2Results posted
• A Study of Abemaciclib (LY2835219) in Participants With Breast CancerActive, not recruitingNCT02763566Phase 3Results posted
• Palbociclib In Combination With Letrozole As Treatment Of Post-Menopausal Women With HR+, HER2- Advanced Breast CancerCompletedNCT02679755Phase 4Results posted
• Exemestane in Post-Menopausal Women With NSCLCCompletedNCT02666105Phase 2Results posted
• Palbociclib Plus Letrozole For Postmenopausal Women With HR(+) HER2(-) Advanced Breast Cancer For Whom Letrozole Is Deemed AppropriateCompletedNCT02600923Phase 3Results posted
• Alternative Dosing of Exemestane Before Surgery in Treating Postmenopausal Patients With Stage 0-II Estrogen Positive Breast CancerCompletedNCT02598557Phase 2Results posted
• Pilot of Letrozole for Uterine MyomasCompletedNCT02470741Phase 4Results posted
• A Neoadjuvant Study of Abemaciclib (LY2835219) in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast CancerCompletedNCT02441946Phase 2Results posted
• Effect of Increased Circulating Androgens on Granulosa Cell Responses to FSH.CompletedNCT02389088Not applicableResults posted
• Study Evaluating the Timing of Intrauterine Insemination in Relation to Positive Home Ovulation Prediction KitCompletedNCT02294773Not applicableResults posted
• Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity CancerCompletedNCT02283658Phase 2Results posted
• Everolimus and Letrozole or Hormonal Therapy to Treat Endometrial CancerCompletedNCT02228681Phase 2Results posted
• Endocrine Response in Women With Invasive Lobular Breast CancerCompletedNCT02206984Phase 2Results posted
• Bay98-7196, Dose Finding / POC StudyCompletedNCT02203331Phase 2Results posted
• ER Reactivation Therapy for Breast CancerCompletedNCT02188745Phase 2Results posted
• S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast CancerTerminatedNCT02137837Phase 3Results posted
• Aromatase Inhibitor Growth Study: Letrozole vs. AnastrozoleCompletedNCT02137538Phase 4Results posted
• GCC 1366: Anti-Proliferative Response to NeoAdjuvant AIs in Overweight and Obese PatientsTerminatedNCT02095184Not applicableResults posted
• To Assess Safety and Effect of Olaparib on the Pharmacokinetics of Anastrozole, Letrozole & Tamoxifen, and Their Effect on Olaparib, in Patients With Advanced Solid CancerCompletedNCT02093351Phase 1Results posted
• Phase III Palbociclib With Endocrine Therapy vs. Capecitabine in HR+/HER2- MBC With Resistance to Aromatase InhibitorsCompletedNCT02028507Phase 3Results posted
• Presurgical Treatment With Letrozole in Patients With Early-stage Breast Cancer.CompletedNCT02010021Not applicableResults posted
• The Role of Estrogen in Luteinizing Hormone Surge and OvulationCompletedNCT01999569Phase 4Results posted
• Exemestane and Cyclophosphamide for Metastatic Breast CancerCompletedNCT01963481Phase 2Results posted
• Preoperative Hormone Therapy for Postmenopausal Women With ER+ Clinical Stage T2-4 TumorsCompletedNCT01831076Phase 2Results posted
• A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial CarcinomaCompletedNCT01797523Phase 2Results posted
• Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast CancerCompletedNCT01698918Phase 2Results posted
• Aromatase Inhibitor Host Factors StudyCompletedNCT01669343Not applicableResults posted
• Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)CompletedNCT01642186Phase 2Results posted
• Anastrozole in Patients With Pulmonary Arterial HypertensionCompletedNCT01545336Phase 2Results posted
• Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast CancerTerminatedNCT01499160Phase 2Results posted
• Reproductive Hormonal Alterations in ObesityCompletedNCT01457703Not applicableResults posted
• Study of MEDI-573 Plus Standard Endocrine Therapy for Women With Hormone-sensitive Metastatic Breast CancerCompletedNCT01446159Phase 2Results posted
• Letrozole in Treating Postmenopausal Women With Ductal Carcinoma in SituCompletedNCT01439711Phase 2Results posted
• Neo-adjuvant Therapy With Anastrozole Plus Pazopanib in Stage II and III ER+ Breast CancerTerminatedNCT01394211Phase 2Results posted
• Pilot Study Estradiol Followed by Exemestane Hormone Receptor + Metastatic Breast CancerCompletedNCT01385280Not applicableResults posted
• Goserelin and Letrozole or Anastrozole in Premenopausal Patients With Stage II-III Estrogen Receptor-Positive Breast CancerTerminatedNCT01368263Phase 2Results posted
• Letrozole for LymphangioleiomyomatosisCompletedNCT01353209Phase 2Results posted
• Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast CancerActive, not recruitingNCT01272037Phase 3Results posted
• Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short StatureCompletedNCT01248416Phase 3Results posted
• Multicenter Follow Up Study Of Subjects Who Participated In An Original Protocol Of Exemestane Vs. Megestrol Acetate In Postmenopausal Women With Metastatic Breast CancerCompletedNCT01237327Phase 3Results posted
• Entinostat and Anastrozole in Treating Postmenopausal Women With TNBC That Can Be Removed by SurgeryTerminatedNCT01234532Phase 2Results posted
• Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast CancerCompletedNCT01231659Phase 2Results posted
• Evaluation of an Anti-cancer Immunotherapy Combined With Standard Neoadjuvant Treatment in Patients With WT1-positive Primary Invasive Breast CancerTerminatedNCT01220128Phase 2Results posted
• ITT4 Intratesticular Hormonal Milieu in Man (ITT4)CompletedNCT01215292Phase 1/2Results posted
• Anastrozole 1 mg Tablets Under Fed ConditionsCompletedNCT01183390Phase 1Results posted
• Anastrozole 1 mg Tablets Under Fasting ConditionsCompletedNCT01182181Phase 1Results posted
• Aromasin® Interventional Study Of Early Invasive Breast Cancer Patients In ChinaCompletedNCT01176916Phase 4Results posted
• Effect of Aromatase Inhibitors on Breast Magnetic Resonance Imaging (MRI)CompletedNCT01129622Phase 2Results posted
• Bioequivalence Study of Letrozole 2.5 mg TabletsCompletedNCT01084499Not applicableResults posted
• Letrozole and RAD001 With Advanced or Recurrent Endometrial CancerActive, not recruitingNCT01068249Phase 2Results posted
• Assessment of Multiple Intrauterine Gestations From Ovarian StimulationCompletedNCT01044862Phase 3Results posted
• RCT of Fixed vs Titrated Letrozole in Breast Cancer Patient Undergoing IVFCompletedNCT01035099Phase 4Results posted
• Pre-Surgical Intervention for Targeted Therapies for Breast CancerCompletedNCT01004744Not applicableResults posted
• Letrozole as a Treatment of Endometrial CancerCompletedNCT00997373Not applicableResults posted
• Study of Estrogen Levels in Premenopausal Women Who Have Undergone Surgery for Breast Cancer and Are Receiving Triptorelin and Tamoxifen Citrate or Exemestane on Clinical Trial IBCSG 24-02CompletedNCT00975676Not applicableResults posted
• Exemestane or Docetaxel-Cytoxan in Low Recurrence Score CancersCompletedNCT00941330Phase 2Results posted
• Fulvestrant and Anastrozole as Consolidation Therapy in Postmenopausal Women With Advanced Non-small Cell Lung CancerTerminatedNCT00932152Phase 2Results posted
• Anti-Hormone Therapy (With Anastrazole and Fulvestrant) Before Surgery to Treat Postmenopausal Women With Breast Cancer.CompletedNCT00921115Phase 2Results posted
• Extended Endocrine Therapy for Premenopausal Women With Breast CancerCompletedNCT00903162Phase 2Results posted
• Letrozole in Women With Advanced Estrogen/Progesterone Receptor Positive Uterine LeiomyosarcomaCompletedNCT00856050Phase 2Results posted
• Exemestane in Treating Postmenopausal Women With Stage IV Breast CancerCompletedNCT00810797Phase 2Results posted
• Do Aromatase Inhibitors (AIs) Decrease Intestinal Calcium Absorption?CompletedNCT00766532Phase 4Results posted
• Letrozole in Breast Cancer Who Have Received 5 Years of Aromatase Inhibitor TherapyCompletedNCT00754845Phase 3Results posted
• CEP-1 Hormonal Regulation of Circulating Endothelial Progenitor Cells and HDL-C in MenCompletedNCT00729859Phase 2Results posted
• Pregnancy in Polycystic Ovary Syndrome IICompletedNCT00719186Phase 3Results posted
• Dose Ranging Study of the Safety and Efficacy of R115966 in Plaque PsoriasisCompletedNCT00716144Phase 2Results posted
• Rheumatological Evaluation of Anastrozole and Letrozole as Adjuvant Treatment in Post-menopausal Women With Breast CancerCompletedNCT00688909Phase 4Results posted
• Estrogen in Postmenopausal Women With ER Positive Metastatic Breast Cancer After Failure of Sequential Endocrine TherapyTerminatedNCT00661531Phase 2Results posted
• Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02CompletedNCT00659373Phase 3Results posted
• Phase I/II Trial of Letrozole and Sorafenib in Post-Menopausal Hormone-Receptor + Breast CancerCompletedNCT00634634Phase 1/2Results posted
• Flaxseed, Aromatase Inhibitors and Breast Tumor CharacteristicsCompletedNCT00612560Not applicableResults posted
• Arimidex/Tamoxifen Neo Adjuvant Study in Premenopausal Patients With Breast Cancer Under Anti Hormonal TreatmentCompletedNCT00605267Phase 3Results posted
• Study of Breast Cancer Prevention by Letrozole in High Risk WomenCompletedNCT00579826Phase 2Results posted
• Aromatase Inhibitors in Premenopausal Breast Cancer Patients With Chemotherapy-Induced Ovarian FailureTerminatedNCT00555477Phase 2Results posted
• Letrozole in Preventing Cancer in Postmenopausal Women Who Have Received 4-6 Years of Hormone Therapy for Hormone Receptor-Positive, Lymph Node-Positive, Early-Stage Breast CancerCompletedNCT00553410Phase 3Results posted
• Intermittent Letrozole Therapy in Postmenopausal Women With Metastatic Breast CancerTerminatedNCT00549822Phase 2Results posted
• Liver Safety Under Upfront Arimidex vs TamoxifenCompletedNCT00537771Phase 4Results posted
• Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast CancerCompletedNCT00530868Phase 2Results posted
• Letrozole in Patients With Ovarian TumorsTerminatedNCT00505661Phase 2Results posted
• PhII Neo-Adjuvant Letrozole & Lapatinib in Pts w/HER2+ & Hormone Receptor+ Operable Breast CA SPORETerminatedNCT00499681Phase 2Results posted
• Randomized Phase II Study of Preoperative Letrozole (Femara) in Combination With Avastin in Hormone Receptor Positive Breast CancerTerminatedNCT00461773Phase 2Results posted
• Aromatase Inhibitors in the Treatment of Male InfertilityTerminatedNCT00440180Phase 3Results posted
• Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer PatientsCompletedNCT00432172Phase 2Results posted
• Vitamin D Deficiency, Muscle Pain, Joint Pain, and Joint Stiffness in Postmenopausal Women Receiving Letrozole For Stage I-III Breast CancerCompletedNCT00416715Phase 2Results posted

← Aromatase inhibitors overview