Aromatase inhibitors: all 608 studies that test it
Page 1 of 7. Open to participants first (88), then studies with results posted, then the rest; newest registration first within each.
- De-EscaLaTion of Aromatase Inhibitor Therapy: A Randomized Phase II Study of De-escalated Letrozole in Hormone Receptor-Positive Early Breast CancerNot yet recruitingNCT07866430Phase 2
- Chemotherapy Exemption in Elderly Women With Node-Positive ER+/HER2- Breast CancerNot yet recruitingNCT07826052Phase 2
- E.N.D.E.A.V.O.R.: An Exemestane Needed Dose Efficacy and Verification as an Ovulation Induction Regimen StudyRecruitingNCT07706374Phase 1
- Kumorixilib Plus Capecitabine and Letrozole for Neoadjuvant Treatment of HR-Positive HER2-Negative Breast CancerNot yet recruitingNCT07691333Phase 2
- Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA TrialNot yet recruitingNCT07676331Phase 2
- Letrozole Versus Methotrexate for Management of Undisturbed Ectopic PregnancyNot yet recruitingNCT07624903Phase 2
- Neoadjuvant Dalpiciclib + AI → SHR-A1811 for HR+/HER2-Low Breast CancerNot yet recruitingNCT07618923Phase 2
- Efficacy and Safety of Culmerciclib Plus Aromatase Inhibitors in a Response-Adapted Neoadjuvant Strategy for Highly Proliferative ER-Positive/HER2-Negative Breast CancerRecruitingNCT07616453Phase 2
- Fovinaciclib Plus Aromatase Inhibitors and Dual HER2 Blockade in a Response-Adapted Neoadjuvant Strategy for HR-Positive/HER2-Positive Early Breast CancerRecruitingNCT07616427Phase 2
- Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in MalesRecruitingNCT07604272Phase 1
- Efficacy and Safety of Dalpiciclib Combined With Endocrine Adjuvant Therapy for Early HR +/HER2- Breast Cancer: a Multicenter, Prospective Clinical StudyRecruitingNCT07581834Phase 2
- Optimization of Dynamic Neoadjuvant Therapy Strategies for HER2-Positive Breast Cancer Based on HER2-PET/CT Molecular ImagingNot yet recruitingNCT07527806Phase 2
- Randomized Double-Blind Phase II Trial of Baby Exemestane Versus Baby Tamoxifen in Post-Menopausal Women at High Risk for Breast CancerNot yet recruitingNCT07499999Phase 2
- Dalpiciclib With or Without Entinostat and Letrozole in HR+/HER2- Early Breast CancerRecruitingNCT07492394Phase 2
- A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Lobular Breast CancerRecruitingNCT07483307Phase 2
- FET-LET-2x2: Clinical Pregnancy Rates After Frozen Embryo Transfer in Natural and Modified Natural CyclesRecruitingNCT07425990Not applicable
- Ribociclib in Hormone Receptor-positive, HER2-negative Early Breast Cancer With Residual Disease After Neoadjuvant ChemotherapyRecruitingNCT07400523Phase 3
- Elacestrant and Exemestane for Patients With Pretreated HR+/HER2- Metastatic Breast Cancer and [18F] FES-avid Lesions (COMBINE)RecruitingNCT07395336Phase 2
- Neoadjuvant Letrozole in Postmenopausal Women With Hormone Receptor-Positive, HER2-Negative, Node Positive, Early-Stage Breast Cancer.Not yet recruitingNCT07394946Phase 2
- Refining Fertility-sparing Treatment in Endometrial Carcinoma Based on Molecular ClassificationRecruitingNCT07319429Phase 2/3
- An Exploratory Study of Pertuzumab and Trastuzumab in Combination With Palbociclib and Exemestane as Neoadjuvant Therapy for Triple-Positive Breast CancerNot yet recruitingNCT07299890Phase 2
- Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed MiscarriageRecruitingNCT07160855Phase 4
- De-escalation Therapy in Stage I ER-Positive Breast Cancer: A Non-Inferiority TrialNot yet recruitingNCT07153757Phase 3
- Use of Aromatase Inhibitor Before Misoprostol in Medical Termination of MiscarriageRecruitingNCT07109947Not applicable
- Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer PatientsRecruitingNCT07071038Phase 2
- Chemo-free in Older (≥65) Node-Positive ER+/HER2- Breast CancerNot yet recruitingNCT07005557Phase 3
- A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)RecruitingNCT06979596Phase 2
- ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast CancerRecruitingNCT06970912Phase 2
- FET in AdenomyosisNot yet recruitingNCT06913075Not applicable
- Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)RecruitingNCT06757634Phase 3
- Letrozole Versus Mifepristone and Misoprostol in Silent MiscarriageNot yet recruitingNCT06733727Not applicable
- Efficacy and Safety of Ribociclib Combined With AI Versus Physician&Amp;#39;s Choice of Chemotherapy Sequential Endocrine Therapy in ER Middle-low-expression/HER2-negative Advanced Breast Cancer (Rachel)RecruitingNCT06656624Phase 2
- Pre-Operative Window of ET to Inform RT Decisions (POWER II)RecruitingNCT06507618Phase 3
- Combination Letrozole and Clomiphene Citrate Versus Letrozole AloneRecruitingNCT06507332Not applicable
- A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian CancerRecruitingNCT06394804Phase 2
- Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast CancerRecruitingNCT06380751Phase 3
- GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer PatientsRecruitingNCT06379113Phase 2/3
- ALPINE: Maintenance Letrozole/AbemaciclibRecruitingNCT06366347Phase 2
- Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer.RecruitingNCT06364267Phase 2
- Molecular Analyses to Predict Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast CancerRecruitingNCT06361940Phase 2
- Use of Letrozole for Ectopic PregnancyRecruitingNCT06354439Phase 4
- Assessing the Efficacy and Safety of Anti-HER2 Therapy in Nigerian Women With HER2+ Breast Cancer Before and After SurgeryRecruitingNCT06348134Phase 2
- Optimizing Extended Adjuvant Endocrine Therapy in Patients With Breast CancerNot yet recruitingNCT06223698Phase 3
- Endometrial Preparation in Frozen Embryo Transfer CyclesRecruitingNCT06181305Phase 4
- Prescription of Letrozole for Uterine MyomaRecruitingNCT06143631Phase 4
- RADIANT: Pre-op Radiation With Abemaciclib and LetrozoleRecruitingNCT06139107Phase 1
- A Study of Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before SurgeryRecruitingNCT06127979Not applicable
- DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as TreatmentRecruitingNCT06075953Phase 2
- The Effectiveness of the Letrozole-induced Endometrial Preparation Protocol in Frozen-thawed Embryo Transfer (FET)RecruitingNCT06006091Not applicable
- Abemaciclib and Letrozole in Patients With Estrogen Receptor-positive Rare Ovarian CancerRecruitingNCT05872204Phase 2
- Dalpiciclib With Endocrine Therapy for Advanced Breast Cancer After CDK4/6 Inhibitor Failure (DAWNA-FES)RecruitingNCT05861830Phase 3
- Select the Appropriate Population for Adding CDK4/6i to Neoadjuvant Endocrine TherapyRecruitingNCT05809024Phase 4
- Letrozole in Uterine LeiomyosarcomaRecruitingNCT05649956Phase 2
- Neoadjuvant Dalpiciclib Plus Aromatase Inhibitors in Luminal B/HER2-negative Breast Cancer (DANCER)RecruitingNCT05640778Phase 2
- Pyrotinib Combined With Trastuzumab, Dalpiciclib, Letrozole Versus TCbHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HR +/HER2 + Breast CancerRecruitingNCT05638594Phase 2
- Letrozole for Estrogen/Progesterone Receptor Positive Low-grade Serous Epithelial Ovarian Cancer (LEPRE Trial)RecruitingNCT05601700Phase 3
- Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter SyndromeRecruitingNCT05586802Phase 3
- Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant TherapyRecruitingNCT05582499Phase 2
- Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast CancerRecruitingNCT05524584Phase 2
- Vitamin D and Calcium Supplementation in Breast CancerRecruitingNCT05523609Phase 2/3
- ETHAN - ET for Male BCRecruitingNCT05501704Phase 2
- Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian CystectomyRecruitingNCT05487092Not applicable
- Combination of Abemaciclib and Endocrine Therapy in Hormone Receptor Positive HER2 Negative Locally Advanced or Metastatic Breast Cancer With Focus on Digital Side Effect ManagementRecruitingNCT05362760Phase 4
- The Use of Letrozole or Mifepristone for Pretreatment of Medical Termination of PregnancyRecruitingNCT05341817Phase 4
- GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia PatientsRecruitingNCT05316935Phase 2/3
- Deescalation of Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low RiskRecruitingNCT05297617Phase 2
- Pyrotinib Maleate, Trastuzumab, SHR6390 and Letrozole in Combination for Stage II-III TPBCRecruitingNCT05228951Phase 2
- Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies.RecruitingNCT05190094Phase 2
- Lenvatinib+Letrozole Versus Fulvestrant in Metastatic ER+/HER2- Breast Cancer, Post Progression on Al + CDK4/6 InhibitorRecruitingNCT05181033Phase 2
- Letrozole Plus Metronomic Capecitabine as First-line Treatment for Patients With Recurrent or Metastatic Breast CancerNot yet recruitingNCT04942899Phase 2
- Neoadjuvant Treatment With Palbociclib and Exemestane Plus Trastuzumab and Pyrotinib in Estrogen Receptor (ER)-Positive, HER2-positive Breast CancerNot yet recruitingNCT04858516Phase 2
- Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in SituRecruitingNCT04666961Phase 2
- Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant AbemaciclibRecruitingNCT04614194Phase 2
- Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast CancerRecruitingNCT04553770Phase 2
- IUI With Letrozole Versus in Natural CycleRecruitingNCT04169451Not applicable
- Palbociclib + Letrozole Versus Epirubicin + Cyclophosphamide and Sequential Docetaxel as Neoadjuvant ChemotherapyNot yet recruitingNCT04137640Phase 4
- MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)RecruitingNCT04111978Phase 3
- Comparative Study for the Degree of Biological Changes After Short-term 2 Weeks and 4 Weeks Preoperative Endocrine Therapy in Luminal Breast CancerRecruitingNCT04023292Phase 2
- A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer.RecruitingNCT03906669Phase 2
- RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial CancerRecruitingNCT03675893Phase 2
- Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)RecruitingNCT03624244Phase 2
- Signal TrAnsduction Pathway Activity Analysis in OVarian cancERRecruitingNCT03458221Phase 2/3
- A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruitingNCT03424005Phase 1/2
- Study of Letrozole in Recurrent GliomasRecruitingNCT03122197Early Phase 1
- Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors TrialRecruitingNCT03011684Phase 3
- Adjuvant Ovarian Suppression Plus Aromatase Inhibitor or Tamoxifen in Young WomenRecruitingNCT02914158Phase 3
- The Letrozole Administration During Luteal PhaseNot yet recruitingNCT02686151Phase 3
- Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence ScoreRecruitingNCT02476786Phase 2
- A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic CancerTerminatedNCT06630325Phase 2Results posted
- Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell TumorsCompletedNCT06169124Phase 2Results posted
- Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast CancerTerminatedNCT05384119Phase 1Results posted
- Evaluating the Pharmacokinetics and Drug Interaction Potential of the Botanical Dietary Supplement CinnamonCompletedNCT05157672Early Phase 1Results posted
- Biology Guided Therapy for Breast Cancer for ER PositiveTerminatedNCT04965688Phase 2Results posted
- Onapristone and Anastrozole for the Treatment of Refractory Hormone Receptor Positive Endometrial CancerCompletedNCT04719273Phase 2Results posted
- Letrozole in Patients With Hepatopulmonary SyndromeTerminatedNCT04577001Phase 2Results posted
- Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast CancerCompletedNCT04294225Phase 2Results posted
- Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer PatientsActive, not recruitingNCT04293393Phase 2Results posted
- Pre-Operative Window of Adjuvant Endocrine Therapy to Inform RT Decisions in Older Women With Early-Stage Breast CancerActive, not recruitingNCT04272801Phase 2Results posted
- The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast CancerCompletedNCT04129216Phase 2Results posted
- Assessment and Prevention of Pain During Ovarian Stimulation in Patients With EndometriosisCompletedNCT04002141Phase 2Results posted