Antimetabolites: all 7,305 studies that test it

Page 33 of 74. Open to participants first (1,098), then studies with results posted, then the rest; newest registration first within each.

• MAD Study of IA-14069CompletedNCT05533372Phase 1
• Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid TumorsWithdrawnNCT05531708Phase 1
• Risk-stratification Based Bladder-sparing Modalities for Muscle-invasive Bladder CancerActive, not recruitingNCT05531123Phase 2
• Effect and Safety of Envafolimab Combined With Endostar/S-1 in Second-line of Advanced Non-small Cell Lung CancerStatus unknownNCT05529355Phase 2
• SBRT Combined With PD-1 Antibody and Chemotherapy in Oligometastatic Nasopharyngeal CarcinomaActive, not recruitingNCT05524168Phase 2
• Sintilimab Combined With Regorafenib and HAIC in Patients With Colorectal Liver MetastasisStatus unknownNCT05524155Phase 2
• Methotrexate Combined With Immunotherapy During Radiotherapy for Solid TumorsActive, not recruitingNCT05522582Phase 2
• Evaluation of the Efficacy of Intralesional Injection of Combined Digoxin and Furosemide Versus 5 - Fluorouracil in Treatment of Plantar WartsStatus unknownNCT05520658Not applicable
• A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid LeukemiaActive, not recruitingNCT05520567Phase 1/2
• Exploratory Clinical Study of Penpulimab Combined With SOX in the Perioperative Treatment of Gastric CancerStatus unknownNCT05519202Phase 2
• Gemcitabine With Oxaliplatin (GEMOX) in Patients With Advanced Hepatocellular Carcinoma After Failure of Sorafenib TreatmentCompletedNCT05517239Phase 2
• B7-H3 Targeting CAR-T Cells Therapy for B7-H3 Positive Solid TumorsStatus unknownNCT05515185Early Phase 1
• Comparative Study Between Topical 5-fluorouracil and Latanoprost in Vitiligo.CompletedNCT05513924Phase 2/3
• Novel CAR-T Cell Therapy in the Treatment of Hematopoietic and Lymphoid MalignanciesWithdrawnNCT05513612Phase 1
• Allopurinol Versus Atorvastatin to Prevent Complications of Liver CirrhosisCompletedNCT05511766Phase 2/3
• Study of Osimertinib+Bevacizumab+Chemotherapy for EGFR+ Advanced Non-Small Cell Lung Cancer With Concurrent MutationsStatus unknownNCT05507606Phase 2
• Intralesional 5-fluorouracil Injection for the Treatment of Oral LeukoplakiaWithdrawnNCT05505539Phase 1
• Evaluating Pembrolizumab, Trastuzumab and FLOT as Perioperative Treatment of HER2-positive, Localized Esophagogastric AdenocarcinomaCompletedNCT05504720Phase 2
• Tislelizumab, Gemcitabine and Cisplatin for R/R Hodgkin Lymphoma Followed by Tislelizumab Consolidation in Patients in Metabolic Complete RemissionActive, not recruitingNCT05502250Phase 2
• A Study of Penpulimab and Anlotinib Plus Nab-paclitaxel and Gemcitabine for Metastatic Pancreatic Cancer.CompletedNCT05493995Phase 2
• Surufatinib Combined With TAS-102 in Third-line and Later-line Therapy of Patients With Advanced Pancreatic CancerCompletedNCT05481463Phase 2
• Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain MetastasesTerminatedNCT05477615Phase 2
• Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction CancerActive, not recruitingNCT05476796Phase 2
• Single Arm Study of Azacitidine and Venetoclax for Treatment of Newly Diagnosed Fit Acute Myeloid Leukemia PatientsCompletedNCT05471700Not applicable
• Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease.CompletedNCT05470270Phase 2
• Dalpiciclib Plus Letrozole and CapecitabineStatus unknownNCT05469750Phase 2
• A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Participants With International Prognostic Scoring System Revised (IPSS-R) Low- or Intermediate-risk Myelodysplastic Syndrome (MDS)Active, not recruitingNCT05469737Phase 2/3
• Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal MetastasesStatus unknownNCT05459441Early Phase 1
• Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeActive, not recruitingNCT05457556Phase 3
• A Study of Bisantrene Combined With Cytarabine or With Decitabine for Adult Subjects With Extramedullary AML and MDSWithdrawnNCT05456269Phase 1
• Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid NeoplasmsActive, not recruitingNCT05455294Phase 1
• Camrelizumab Plus Apatinib in Combination With GEMOX (Gemcitabine and Oxaliplatin ) in Patients With Locally Advanced Biliary Tract CancerActive, not recruitingNCT05451290Phase 2
• An Observational Real World Study on the Efficacy and Safety of Toripalimab Injection Combined With TACE in the Treatment of Extrahepatic CholangiocarcinomaStatus unknownNCT05448183Phase 2
• A Study to Assess the Effects of BMS-986371 on the Drug Levels of Methotrexate in the Presence and Absence of SulfasalazineCompletedNCT05445440Phase 1
• Camrelizumab Combined With Intraperitoneal Infusion of Nab-paclitaxel, Intravenous Chemotherapy and S-1 in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis：Single-arm, Prospective Clinical StudyStatus unknownNCT05441254Phase 2
• A Clinical Study of the Efficacy and Safety of Chidamide in Combination With Camrelizumab and Carboplatin or Capecitabine in the Second and Third Line Treatment of Relapsed/Metastatic Triple-negative Breast CancerStatus unknownNCT05438706Phase 2
• Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP PatientsCompletedNCT05433532Phase 2
• Precise Therapy for Refractory HER2 Positive Advanced Breast CancerStatus unknownNCT05429684Phase 3
• Thyroid Associated Orbitopathy Treatment by Methotrexate Against Triamcinolone Periocular InjectionsCompletedNCT05429450Phase 2
• Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum Chitotriosidase Level in PsoriasisStatus unknownNCT05427175Phase 4
• RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSLStatus unknownNCT05425654Phase 2
• Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and SwellingStatus unknownNCT05419752Phase 2/3
• Adjuvant Gemcitabine and Capecitabine Chemotherapy in Resected Pancreatic Cancer Following Neoadjuvant ChemotherapyWithdrawnNCT05415917Phase 2
• Allopurinol Effect on MDA,NO,KIM-1 Urine Levels, RI and Renal Elastography in Kidney Stone Patients Post ESWLCompletedNCT05414669Phase 4
• An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete RemissionActive, not recruitingNCT05413018Phase 2
• Tucidinostat Combined With Metronomic Capecitabine and Endocrine Therapy for Advanced HR-positive, HER2-negative Breast Cancer After CDK4/6 Inhibitor.Status unknownNCT05411380Phase 2
• A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)TerminatedNCT05403450Phase 1
• R-MTX-zanbrutinib in Secondary CNS LymphomaStatus unknownNCT05398224Phase 2
• iTBS-DCS in FibromyalgiaTerminatedNCT05395494Phase 2
• A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy SubjectsCompletedNCT05380934Phase 1
• Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic SyndromeActive, not recruitingNCT05379166Phase 2
• 5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East AfricaCompletedNCT05362955Phase 1
• Combination of Venetoclax, Hypomethylation Agent and Low-dose Cytarabine as a Salvage Therapy for Acute Myeloid LeukemiaStatus unknownNCT05362942Phase 2
• Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML PatientsTerminatedNCT05361057Phase 2
• tailOred dRug repurposIng of dEcitabine in KRAS-dependeNt refracTory pAncreaTic cancErTerminatedNCT05360264Phase 2
• Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-ThalassemiaActive, not recruitingNCT05357482Phase 1/2
• Tucatinib Combined with Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T StudyWithdrawnNCT05356897Phase 2
• Methotrexate in Patients with Early Rheumatoid ArthritisActive, not recruitingNCT05353829Phase 4
• A Study of Mitoxantrone Hydrochloride Liposome Injection Combination Therapy in Chinese Patients With Advanced Solid TumorsStatus unknownNCT05344742Phase 1
• TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant ChemotherapyActive, not recruitingNCT05343013Phase 2
• A Phase II Study of Chiauranib in Combine With Capecitabine in TNBCTerminatedNCT05336721Phase 2
• A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial CarcinomaActive, not recruitingNCT05335941Phase 2
• GM-CLAG in Relapsed/Refractory FLT3-mutated AMLWithdrawnNCT05330377Phase 1
• Study of Chidamide Combined With Cladribine in Refractory/Relapsed Acute Myeloid LeukemiaStatus unknownNCT05330364Phase 2
• A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract MalignanciesCompletedNCT05329766Phase 2
• Orelabrutinib and Obinutuzumab Plus FC Regimen in Treating Newly Diagnosed CLL/SLLStatus unknownNCT05322733Phase 2
• Adjuvant CAPECITABINE in High Risk PSEUDOMYXOMA PERITONEI PatientsStatus unknownNCT05321329Phase 2
• A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to TreatWithdrawnNCT05320380Phase 1/2
• Study of Liposomal Annamycin in Combination With Cytarabine for the Treatment of Subjects With Acute Myeloid Leukemia (AML)CompletedNCT05319587Phase 1/2
• A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung CancerActive, not recruitingNCT05318573Phase 2
• Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin CancersCompletedNCT05315128Phase 2
• Safety and Pharmacokinetic Study of Intranasal 2-DG in Healthy VolunteersCompletedNCT05314933Phase 1
• Efficacy of Tazarotene in Treatment of Verruca PlanaStatus unknownNCT05314127Phase 2
• TAS-102 Combined With Bevacizumab and Tislelizumab Third-line or Above in the Treatment of Liver Metastasis in Colorectal CancerStatus unknownNCT05314101Phase 2
• MTX Hold During Covid-19 BoosterStatus unknownNCT05313061Phase 3
• Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal MetastasisStatus unknownNCT05305885Not applicable
• Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor MutationsCompletedNCT05299125Phase 2
• Combining Afatinib and Concurrent Chemotherapy, Followed by Osimertinib and Concurrent Chemotherapy, in Untreated EGFR Positive NSCLC TumorsCompletedNCT05298176Phase 2
• Envafolimab Combined With Endostar and Chemotherapy for First-line Treatment of Advanced Pancreatic CancerStatus unknownNCT05298020Phase 2
• Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric CancersWithdrawnNCT05296005Phase 1
• Tisleizumab Combined With Lenvatinib and XELOX Regimen (Oxaliplatin Combined With Capecitabine) in the First-line Treatment of Advanced and Unresectable Biliary Tract TumorsStatus unknownNCT05291052Phase 2
• Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal CarcinomaWithdrawnNCT05290194Phase 2
• Intrathecal Pemetrexed for Leptomeningeal MetastasisCompletedNCT05289908Phase 1/2
• Zanubrutinib Followed Zanubrutinib Plus FCR / BR in Newly Diagnosed Symptomatic CLL/SLLStatus unknownNCT05287984Phase 2
• Thiopurine Enhanced Mutations for PD-1/Ligand-1 EfficacyCompletedNCT05276284Phase 1/2
• Study of Chemotherapy and PD-1 Inhibitor Combination With Anti-angiogenesis to Treat Elderly Lung CancerStatus unknownNCT05273814Phase 1
• Clinical Efficacy and Safety of CD47 Monoclonal Antibody Combined With Azacitidine in the Treatment of Recurrent AML After TransplantationStatus unknownNCT05266274Not applicable
• Decitabine Plus Penpulimab as Second-line Therapy for Advanced ESCC Treated With PD-1 BlockadeStatus unknownNCT05265962Phase 2
• 8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid LeukemiaSuspendedNCT05263284Phase 1
• Anlotinib Plus Chemotherapy as First-line Therapy for Gastrointestinal Tumor Patients With Unresectable Liver Metastasis (ALTER-G-001)Status unknownNCT05262335Phase 2
• Lenvatinib in Combination With Carboplatin Pemetrexed and Pembrolizumab for NSCLC With EGFR MutationsCompletedNCT05258279Phase 2
• Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29Active, not recruitingNCT05253846Phase 2
• Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous GoutCompletedNCT05253833Phase 2
• Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS)Active, not recruitingNCT05253118Phase 2
• Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors, the ComPareNET TrialActive, not recruitingNCT05247905Phase 2
• HLX07+HLX10+Chemotherapy or HLX07 Monotherapy in Patients With Advanced Metastatic Gastric CancerStatus unknownNCT05246982Phase 2
• Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract CancerCompletedNCT05239169Phase 2
• SMMART Adaptive Clinical Treatment (ACT) TrialWithdrawnNCT05238831Early Phase 1
• Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell LymphomaWithdrawnNCT05228249Phase 1
• Margetuximab Plus Tucatinib and Capecitabine in HER2-positive Metastatic Breast CancerWithdrawnNCT05227131Phase 2

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