Antimetabolites: all 8,294 studies that test it

Page 14 of 83. Open to participants first (1,149), then studies with results posted, then the rest; newest registration first within each.

• Capecitabine and Temozolomide for Treatment of Recurrent Pituitary AdenomasTerminatedNCT03930771Phase 2Results posted
• Bioequivalence of Azathioprine Suspension 10 mg/mL (Jayempi) Versus Azathioprine Tablet 50mg (Imurek®)CompletedNCT03930264Phase 1Results posted
• Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated GliomaTerminatedNCT03927222Phase 2Results posted
• Study of Oral Vinorelbine Plus Capecitabine Versus Taxane-gemcitabine Combinations as 1st Line Chemotherapy in Metastatic Breast CancerCompletedNCT03887130Phase 2Results posted
• Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative NeoplasmsTerminatedNCT03878199Phase 1/2Results posted
• PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate CancerActive, not recruitingNCT03873805Phase 1Results posted
• Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)TerminatedNCT03869190Phase 1/2Results posted
• Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney DiseaseTerminatedNCT03865407Phase 2Results posted
• Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast CancerCompletedNCT03853707Phase 1/2Results posted
• A Study Evaluating the Safety and Efficacy of Idasanutlin in Combination With Cytarabine and Daunorubicin in Patients Newly Diagnosed With Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete RemissionTerminatedNCT03850535Phase 1/2Results posted
• Analyzing Childhood Recall Antigens in Patients With Pancreatic CancerTerminatedNCT03848182Phase 2Results posted
• Phase I/II Trial of CPX-351 + Palbociclib in Patients With Acute Myeloid LeukemiaCompletedNCT03844997Phase 1/2Results posted
• M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)CompletedNCT03840915Phase 1/2Results posted
• Hydroxyurea Therapy: Optimizing Access in Pediatric Populations EverywhereTerminatedNCT03825341Phase 2Results posted
• Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeCompletedNCT03813147Phase 1Results posted
• SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)CompletedNCT03806452Phase 2Results posted
• Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract CancerCompletedNCT03785873Phase 1/2Results posted
• Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid ArthritisTerminatedNCT03781375Phase 3Results posted
• Study of Peposertib in Combination With Capecitabine and RT in Rectal CancerCompletedNCT03770689Phase 1/2Results posted
• Pharmacokinetics of Oral Hydroxyurea SolutionCompletedNCT03763656Phase 1/2Results posted
• A Study of Brequinar in Subjects With Relapsed/Refractory Acute Myeloid LeukemiaTerminatedNCT03760666Phase 1/2Results posted
• Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck CancerCompletedNCT03754933Phase 1/2Results posted
• APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)CompletedNCT03745716Phase 3Results posted
• Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 PatientsTerminatedNCT03745326Phase 1/2Results posted
• Effects of Cladribine Tablets on the PK of Microgynon®CompletedNCT03745144Phase 1Results posted
• Gemcitabine, Bendamustine, and Nivolumab in Patients With Relapsed or Refractory Classical Hodgkin LymphomaCompletedNCT03739619Phase 1/2Results posted
• Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung CancerTerminatedNCT03737994Phase 2Results posted
• Liposomal Irinotecan, Fluorouracil and Leucovorin in Treating Patients With Refractory Advanced High Grade Neuroendocrine Cancer of Gastrointestinal, Unknown, or Pancreatic OriginTerminatedNCT03736720Phase 2Results posted
• Investigational Therapeutics for the Treatment of People With Ebola Virus DiseaseCompletedNCT03719586Phase 2/3Results posted
• Study of Avelumab and Cetuximab Plus Gemcitabine and Cisplatin in Participants With NSCLCCompletedNCT03717155Phase 2Results posted
• Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar, FOLFIRINOX or GemcitabineTerminatedNCT03714555Phase 2Results posted
• Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung CancerTerminatedNCT03713944Phase 2Results posted
• Pevonedistat and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission AMLTerminatedNCT03709576Phase 2Results posted
• Efficacy and Safety of Oral Azacitidine (CC-486) Compared to Investigator's Choice Therapy in Patients With Relapsed or Refractory Angioimmunoblastic T Cell LymphomaCompletedNCT03703375Phase 3Results posted
• Pinometostat and Azacitidine in Treating Patients With Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia With 11q23 RearrangementCompletedNCT03701295Phase 1/2Results posted
• Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic CancerCompletedNCT03697564Phase 2Results posted
• Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell LymphomaActive, not recruitingNCT03696784Phase 1Results posted
• A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or CholangiocarcinomaCompletedNCT03693807Phase 2Results posted
• Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility TrialCompletedNCT03690921Phase 2Results posted
• TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) AdenocarcinomaCompletedNCT03686488Phase 2Results posted
• Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung CancerTerminatedNCT03662074Phase 2Results posted
• Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric AcidCompletedNCT03648996Phase 2Results posted
• MT2017-45: CAR-T Cell Therapy for Heme MalignanciesActive, not recruitingNCT03642626Phase 2Results posted
• Dragon III: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric CancerCompletedNCT03636893Phase 2Results posted
• Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled GoutCompletedNCT03635957Phase 4Results posted
• Management of Severe Acute Malnutrition in SCD, in Northern NigeriaCompletedNCT03634488Phase 2Results posted
• Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell LymphomaCompletedNCT03623373Phase 2Results posted
• Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder CancerCompletedNCT03617913Phase 2Results posted
• TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated DonorsTerminatedNCT03615144Phase 2Results posted
• Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched DonorsTerminatedNCT03615105Phase 2Results posted
• MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study.CompletedNCT03611556Phase 1/2Results posted
• A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi AnemiaTerminatedNCT03600909Phase 2Results posted
• Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell LymphomasActive, not recruitingNCT03598998Phase 1/2Results posted
• Cardiac Safe Transplants for Systemic SclerosisTerminatedNCT03593902Phase 2/3Results posted
• QUILT-3.080: NANT Pancreatic Cancer VaccineTerminatedNCT03586869Phase 1/2Results posted
• Venetoclax, Carmustine, Etoposide, Cytarabine, and Melphalan Before Stem Cell Transplant in Treating Participants With Relapsed or Refractory Non-Hodgkin LymphomaCompletedNCT03583424Phase 1/2Results posted
• Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct CancerCompletedNCT03579771Phase 2Results posted
• Vyxeos(CPX-351) in Adults w R/R Acute Lymphoblastic LeukemiaCompletedNCT03575325Phase 2Results posted
• Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid LeukemiaCompletedNCT03573024Phase 2Results posted
• A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local TreatmentCompletedNCT03572387Phase 2Results posted
• Omacetaxine + Azacitidine in Untreated Patients With High Grade MDSActive, not recruitingNCT03564873Phase 1/2Results posted
• Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung CancerTerminatedNCT03559049Phase 1/2Results posted
• Gemcitabine, Cisplatin, Plus Nivolumab in Patients With Muscle-invasive Bladder Cancer With Selective Bladder SparingCompletedNCT03558087Phase 2Results posted
• CC486-CHOP in Patients With Previously Untreated Peripheral T-cell LymphomaCompletedNCT03542266Phase 2Results posted
• A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic CancerCompletedNCT03535727Phase 1/2Results posted
• D-cycloserine for the Treatment of Chronic, Refractory Low Back PainTerminatedNCT03535688Phase 2Results posted
• Gemtuzumab Ozogamicin With G-CSF, Cladribine, Cytarabine & Mitoxantrone for Untreated AML & High-Grade Myeloid NeoplasmCompletedNCT03531918Phase 1/2Results posted
• Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung CancerCompletedNCT03520842Phase 2Results posted
• Efficacy/Safety of CPI-613 in Combination With HD Cyt. and Mito. vs HD Cyt. and Mito. in Older Patients With R/R AMLTerminatedNCT03504410Phase 3Results posted
• Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMDTerminatedNCT03501979Phase 2Results posted
• PK,PD,Safety and Tolerability of Multiple Dose Regimens of MT-3724 With Gemcitabine and Oxaliplatin for the Treatment of Patients With Relapsed/Refractory Diffuse Large B Cell Non-Hodgkin's LymphomaTerminatedNCT03488251Phase 2Results posted
• OXEL: Immune Checkpoint or Capecitabine or Combination Therapy as Adjuvant Therapy for TNBC With Residual DiseaseCompletedNCT03487666Phase 2Results posted
• Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' ExpressionCompletedNCT03480360Phase 3Results posted
• A Study of SHR-1210 in Combination With Capecitabine + Oxaliplatin or Apatinib in Treatment of Advanced Gastric CancerCompletedNCT03472365Phase 2Results posted
• Gemcitabine Plus Ascorbate for Sarcoma in AdultsTerminatedNCT03468075Phase 2Results posted
• M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the PancreasTerminatedNCT03451773Phase 1/2Results posted
• ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung CancerCompletedNCT03449901Phase 2Results posted
• A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer TreatmentCompletedNCT03428958Phase 1/2Results posted
• A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid LeukemiaCompletedNCT03416179Phase 3Results posted
• Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal CancerCompletedNCT03396926Phase 2Results posted
• OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT03390296Phase 1/2Results posted
• QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have ProgressedTerminatedNCT03387111Phase 1/2Results posted
• QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care TherapyTerminatedNCT03387098Phase 1/2Results posted
• QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy.TerminatedNCT03387085Phase 1/2Results posted
• Basket Study to Evaluate the Therapeutic Activity of Simlukafusp Alfa as a Combination Therapy in Participants With Advanced and/or Metastatic Solid TumorsTerminatedNCT03386721Phase 2Results posted
• Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)CompletedNCT03369665Phase 4Results posted
• Nivolumab Plus Cisplatin/Pemetrexed or Cisplatin/Gemcitabine as Induction in Resectable Non-Small Cell Lung CancerTerminatedNCT03366766Phase 2Results posted
• Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the LiverCompletedNCT03366155Phase 2Results posted
• Evaluation of the Onset of Action in Highly Active MS (MAGNIFY)CompletedNCT03364036Phase 4Results posted
• DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid LeukemiaCompletedNCT03358719Phase 1Results posted
• A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCLCompletedNCT03349333Phase 3Results posted
• Pre-Operative Trial (PGHA vs. PGH) for Resectable Pancreatic CancerTerminatedNCT03344172Phase 2Results posted
• KeyLargo: Pembrolizumab + Oxaliplatin + Capecitabine in Gastric CancerCompletedNCT03342937Phase 2Results posted
• Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor TransplantationCompletedNCT03342196Phase 2Results posted
• A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Small Cell Lung Cancer)TerminatedNCT03337698Phase 1/2Results posted
• Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary CancerActive, not recruitingNCT03337087Phase 1/2Results posted
• A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic CancerCompletedNCT03336216Phase 2Results posted
• Investigator Initiated Trial of CPX-351 for Untreated Acute Myeloid LeukemiaCompletedNCT03335267Phase 2Results posted
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
• QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care TherapyTerminatedNCT03329248Phase 1/2Results posted

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