Alkylating agents: all 3,295 studies that test it

Page 19 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.

• Neoadjuvant Short-term Intensive Chemoresection Versus Standard Adjuvant Intravesical Instillations in NMIBCCompletedNCT03348969Phase 4
• TEAM (Thiotepa, Etoposide, Cytosar, Melphalan ) for AutoSCT in LymphomaCompletedNCT03346096Phase 2
• A Study of Safety and Efficacy of Nivolumab and Bendamustine (NB) in Patients With Relapsed/Refractory Hodgkin's LymphomaCompletedNCT03343652Phase 1/2
• Addition of Gemcitabine to Pre Allo-HSCT Conditioning for Acute Lymphoblastic LeukemiaStatus unknownNCT03339700Phase 2
• Chidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCTStatus unknownNCT03336632Phase 2
• Carfilzomib, Cyclophosphamide, Dexamethasone in Multiple MyelomaStatus unknownNCT03336073Phase 2
• Phase 1b Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal CancerCompletedNCT03332576Phase 1
• Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive CytologyCompletedNCT03330028Phase 1
• Study of Personalized Melphalan Dosing in the Setting of Autologous TransplantWithdrawnNCT03328936Phase 2
• Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/LymphomaCompletedNCT03328104Phase 1
• BeEAC Conditioning Regimen in Malignant Lymphoma Subjects With Indications to Autologous Hematopoietic Stem-cell TransplantationStatus unknownNCT03315520Phase 2
• Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined ImmunodeficiencyStatus unknownNCT03315078Phase 1/2
• Concomitant Association of Ultrafractionated Brain Irradiation - Temozolomide in Inoperable Primary Glioblastoma MultiformeCompletedNCT03310372Phase 2
• Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant TumorsStatus unknownNCT03302403Not applicable
• 5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma MultiformeCompletedNCT03291990Early Phase 1
• ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016Active, not recruitingNCT03286634Phase 2
• Study to Compare Capecitabine Combined With Dacarbazine(CAPDTIC) Versus Capecitabine Combined Temozolomide(CAPTEM) in Advanced and Metastatic Gastrointestinal Pancreatic and Esophageal Neuroendocrine TumorStatus unknownNCT03279601Phase 2
• Quality of Life and Neurocognitive FunctioningCompletedNCT03257618Not applicable
• Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03247088Phase 1/2
• Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory GlioblastomaCompletedNCT03243851Phase 2
• International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)Status unknownNCT03243461Phase 3
• The Safety and Efficacy of Pomalidomide in Combination With Cyclophosphamide and Dexamethasone (PCD) in the Transplant-ineligible Patients With Relapsed and/or Refractory Multiple Myeloma (MM)CompletedNCT03242460Phase 2
• A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin CStatus unknownNCT03242317Phase 4
• Study of CD19/CD22 Chimeric Antigen Receptor T Cells in Children & Young Adults w/ Recurrent or Refractory B Cell MalignanciesActive, not recruitingNCT03241940Phase 1
• Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL AmyloidosisCompletedNCT03236792Phase 1/2
• NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed GlioblastomaCompletedNCT03232424Phase 1
• Extended Follow-up of Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA NephropathyStatus unknownNCT03218852Phase 4
• Phase I/IIa Study of Concomitant Radiotherapy With Olaparib and Temozolomide in Unresectable High Grade Gliomas PatientsActive, not recruitingNCT03212742Phase 1/2
• A Study of Tegafur Combined With Temozolomide Versus Tegafur Combined With Temozolomide and Thalidomide in Subjects With Advanced Extrapancreatic Neuroendocrine TumorStatus unknownNCT03204032Phase 2
• A Study of Tegafur Combined With Temozolomide Versus Tegafur Combined With Temozolomide and Thalidomide in Subjects With Advanced Pancreatic Neuroendocrine TumorStatus unknownNCT03204019Phase 2
• Randomized Clinical Trial Evaluating the Use of the Laser-Assisted Immunotherapy (LIT/inCVAX) in Advanced Breast CancerTerminatedNCT03202446Phase 3
• Cyclophosphamide Versus Mycophenolate Mofetil in Lupus NephritisCompletedNCT03200002Phase 2
• Study of Pembrolizumab, Radiation and Immune Modulatory Cocktail in Cervical/Uterine CancerCompletedNCT03192059Phase 2
• Pembrolizumab Cyclophosphamide and Lenalidomide for Patients With Relapsed Multiple MyelomaWithdrawnNCT03191981Phase 1/2
• Risk Adapted Therapy in Diffuse Large B Cell LymphomaStatus unknownNCT03188198Phase 2
• MUK Nine b: OPTIMUM Treatment ProtocolActive, not recruitingNCT03188172Phase 2
• Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia MajorStatus unknownNCT03171831Phase 4
• Evaluation of 2 Intensification Treatment Strategies for Neuroblastoma Patients With a Poor Response to InductionTerminatedNCT03165292Phase 2
• Metronomic Chemotherapy in Elderly Non-fit Patients With Aggressive B-Cell LymphomasCompletedNCT03161054Phase 2
• FIL Study on ABVD DD-DI as Upfront Therapy in HL.CompletedNCT03159897Phase 3
• The p53 Colorectal Cancer TrialTerminatedNCT03149679Phase 2
• PAZIT Study for Children and Young Adults With Relapsed or Refractory SarcomaCompletedNCT03139331Phase 1
• Cyclophosphamide and Alemtuzumab In LymphomaTerminatedNCT03132584Phase 1
• A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before ImplantationStatus unknownNCT03126877Phase 4
• Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid LeukemiaTerminatedNCT03126864Phase 1
• Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic SyndromesActive, not recruitingNCT03121014Phase 2
• Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary MyelofibrosisActive, not recruitingNCT03118492Phase 1
• Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingNCT03117751Phase 2/3
• A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation.TerminatedNCT03101501Phase 4
• Melphalan, Total Marrow Irradiation, and Autologous Stem Cell Transplantation in Treating Patients With High-Risk Multiple MyelomaWithdrawnNCT03100877Phase 1/2
• BCMA Chimeric Antigen Receptor Expressing T Cells in Multiple MyelomaStatus unknownNCT03093168Phase 1
• Haploidentical Stem Cell Transplantation Using Post-Transplant CyclophosphamideTerminatedNCT03088709Phase 2
• Cyclophosphamide vs. Infliximab for Refractory Idiopathic Scleritis (CIRIS)WithdrawnNCT03088293Phase 3
• Percutaneous Hepatic Perfusion vs. Cisplatin/Gemcitabine in Patients With Intrahepatic CholangiocarcinomaStatus unknownNCT03086993Phase 2/3
• Combination Chemotherapy Including Cisplatin, Ifosfamide, Gemcitabine, L-asparaginase, Etoposide and Dexamethasone as Treatment of Newly Diagnosed and Relapsed/Refractory Peripheral T Cell LymphomasStatus unknownNCT03071822Phase 4
• Autologous CD8+ SLC45A2-Specific T Lymphocytes With Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Uveal MelanomaActive, not recruitingNCT03068624Phase 1
• Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic OsteosarcomaStatus unknownNCT03063983Phase 2
• Tandem High Dose Chemotherapy With 131I-MIBG Treatment in High Risk NeuroblastomaStatus unknownNCT03061656Phase 2
• PD-1 Knockout EBV-CTLs for Advanced Stage Epstein-Barr Virus (EBV) Associated MalignanciesStatus unknownNCT03044743Phase 1/2
• A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing ToxicityCompletedNCT03032783Phase 2
• A Study of CD19 Redirected Autologous T Cells for CD19 Positive Systemic Lupus Erythematosus (SLE)Status unknownNCT03030976Phase 1
• Study With Trabectedin Versus Adriamycin Plus Dacarbazine, in Patients With Advanced Solitary Fibrous TumorCompletedNCT03023124Phase 2
• A Dose Increase Finding Study of Doxorubicin Hydrochloride Liposome Injection for Patients With Breast CancerCompletedNCT03017404Not applicable
• Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant GliomaActive, not recruitingNCT03011671Phase 1
• 2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance TherapyActive, not recruitingNCT03004287Phase 2
• Haploidentical BMT With Post-Transplant Cyclophosphamide and BendamustineCompletedNCT02996773Phase 1
• Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-CaribbeansStatus unknownNCT02989207Not applicable
• Paclitaxel,Cyclophosphamide and Dexamethasone for Relapsed or Refractory Multiple MyelomaWithdrawnNCT02985333Phase 2
• Neoadjuvant Chemo-endocrine Therapy Versus Chemotherapy Alone in ER-positive, HER2-negative Breast CancerCompletedNCT02980965Phase 3
• Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade GliomasWithdrawnNCT02976441Early Phase 1
• Extensive Stage Sclc Patients Who Were Benefit From First-line Treatment Accept Temozolomide Maintain TherapeuticStatus unknownNCT02972320Phase 2
• PCD Versus RCD for the Treatment of Patients With Waldenstrom's MacroglobulinemiaStatus unknownNCT02971982Phase 1/2
• Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade GliomasCompletedNCT02970448Early Phase 1
• Hematopoietic Cell Transplantation With Post-transplantation Cyclophosphamide in MDSCompletedNCT02969980Phase 2
• The p53 Breast Cancer TrialActive, not recruitingNCT02965950Phase 2
• Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed LymphomaWithdrawnNCT02961816Phase 2
• Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT02960646Phase 1
• Cyclophosphamide-Bortezomib-Dexamethasone (CyBorD) With Daratumumab (DARA)Status unknownNCT02955810Phase 1
• Adding Mitomycin to BCG as Adjuvant Intravesical Therapy for High-risk Non-Muscle-invasive Bladder CancerActive, not recruitingNCT02948543Phase 3
• PD 0360324 and Cyclophosphamide in Treating Patients With Recurrent High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube CancerWithdrawnNCT02948101Phase 2
• Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma MultiformeStatus unknownNCT02937844Phase 1
• Efficacy of Idarubicin, Cytarabine and Cyclophosphamide (IAC) Regimen in Relapsed/Refractory AMLCompletedNCT02937662Phase 2
• Temozolomide in Treatment of Patients With Primary Central Nervous System LymphomaStatus unknownNCT02934204Phase 2
• CD19-redirected Autologous Cells (CAR-CD19 T Cells)Status unknownNCT02933775Phase 1
• Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors (GAP)Active, not recruitingNCT02932956Phase 1
• Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With GlioblastomaStatus unknownNCT02928575Phase 2
• Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATGCompletedNCT02916979Phase 1
• Glypican 3-specific Chimeric Antigen Receptor Expressing T Cells for Hepatocellular Carcinoma (GLYCAR)CompletedNCT02905188Phase 1
• Doxorubicin Hydrochloride Liposome Injection Combination With Cyclophosphamide vs Pirarubicin Combination With Cyclophosphamide in Patients With Locally Advanced Breast CancerStatus unknownNCT02903524Phase 4
• Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain CancerCompletedNCT02903069Phase 1
• Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled GlaucomaCompletedNCT02901236Phase 2/3
• Nivolumab in Relapsed Pediatric Solid TumorsStatus unknownNCT02901145Phase 1/2
• Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional StatusCompletedNCT02898012Phase 2
• Trial of Neoadjuvant Docetaxel ± Metronomic Capecitabine/CTX Followed by FEC in Women With Operable Triple Negative Breast CancerSuspendedNCT02897050Phase 2
• Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis FungoidesStatus unknownNCT02881749Phase 2
• Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified TreatmentCompletedNCT02881086Phase 3
• Feasibility Study on LITT for Newly Diagnosed GlioblastomaTerminatedNCT02880410Phase 1
• Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell CarcinomaStatus unknownNCT02876978Phase 1
• Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCTCompletedNCT02876679Phase 2
• RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic GliomasCompletedNCT02871843Phase 1

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