Urethral Neoplasms clinical trials
The registry lists 95 studies for Urethral Neoplasms across more than 10 countries. 5 are recruiting or about to start. 5 of them are mainly about Urethral Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Cancer Institute (NCI) (19) · M.D. Anderson Cancer Center (9) · Eastern Cooperative Oncology Group (6) · SWOG Cancer Research Network (6) · European Organisation for Research and Treatment of Cancer - EORTC (4) · Eli Lilly and Company (3) · Cardiff University (3) · Emory University (2)
What is being tested here
Drugs under test in Urethral Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cabozantinib | 1 | 1 | 4 |
| Nivolumab | 1 | 0 | 4 |
| Ipilimumab | 1 | 0 | 2 |
| Tamibarotene | 1 | 0 | 1 |
| Gemcitabine | 0 | 2 | 20 |
| Cisplatin | 0 | 2 | 11 |
| Paclitaxel | 0 | 3 | 10 |
| Carboplatin | 0 | 3 | 6 |
| Doxorubicin | 0 | 1 | 5 |
| Fluorouracil | 0 | 0 | 4 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open · Immune checkpoint inhibitors 1 open · Antimetabolites 26 · Antimitotic agents 19 · Angiogenesis inhibitors 10
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 9
- Dec 2026Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma · Fox Chase Cancer Center
- Dec 2026Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy · National Cancer Institute (NCI)
- Dec 2026ARID1A and/or KDM6A Mutation and CXCL13 Expression · M.D. Anderson Cancer Center
- Dec 202664Cu-GRIP B in Patients With Advanced Malignancies · Rahul Aggarwal
- Feb 2027Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · National Cancer Institute (NCI)
- Mar 2027Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial Carcinoma · Nagoya University
- Jun 2027Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer · National Cancer Institute (NCI)
- Jul 2027Agnostic Therapy in Rare Solid Tumors · Instituto do Cancer do Estado de São Paulo
- Jul 2027Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors · National Cancer Institute (NCI)
Who these studies take
Of the 5 Urethral Neoplasms studies recruiting now, 2 (40%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (80%) | 4 (80%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 4 (80%) | 4 (80%) |
Across all 95 studies, recruiting or not: 1% stop at 75 or younger and 0% at 65; 13% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Urethral Neoplasms studies take
Of 20 phase 2 interventional studies under Urethral Neoplasms, half reached primary completion within 51 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 51 mo36–132 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 95. Browse all 95 → or search them.
- Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary TumorsRecruitingNCT03866382Phase 22 countries
- DESTINY-PANTUMOUR04RecruitingNCT071240001 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- 64Cu-GRIP B in Patients With Advanced MalignanciesRecruitingNCT05888532Phase 1/21 country
- Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial CarcinomaRecruitingNCT06983210Phase 21 country
- Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid TumorsCompletedNCT01352962Phase 11 country
- Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV StudyActive, not recruitingNCT05092958Phase 32 countries
- Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary TumorsActive, not recruitingNCT02496208Phase 11 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid TumorsCompletedNCT00479128Phase 11 country
- ARID1A and/or KDM6A Mutation and CXCL13 ExpressionActive, not recruitingNCT04953104Phase 21 country
- Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung CancersCompletedNCT01846520Not applicable1 country
- A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of InterestCompletedNCT05899361Not applicable1 country
- Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and ImmunotherapyActive, not recruitingNCT04963153Phase 12 countries
- Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial CarcinomaActive, not recruitingNCT04940299Phase 21 country
- Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before SurgeryActive, not recruitingNCT02812420Early Phase 11 country
- Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial CancerActive, not recruitingNCT03237780Phase 21 country
- Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract CancerCompletedNCT00942331Phase 32 countries
- Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial CarcinomaActive, not recruitingNCT032910281 country
- A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial CancerTerminatedNCT03288545Phase 1/26 countries
- Avelumab in Combination With AVB-S6-500 in Patients With Advanced Urothelial CarcinomaActive, not recruitingNCT04004442Phase 11 country
- Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial CarcinomaActive, not recruitingNCT04848519Phase 21 country
- Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or ProstateActive, not recruitingNCT03582475Phase 11 country
- Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal RemnantActive, not recruitingNCT00082706Phase 21 country
- Afatinib in Advanced Refractory Urothelial CancerTerminatedNCT02122172Phase 21 country
- A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder CancerCompletedNCT03219333Phase 28 countries
- A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract CancerCompletedNCT02443324Phase 16 countries
- Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial CarcinomaCompletedNCT03513952Phase 21 country
- A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial CancerCompletedNCT01326871Phase 1/21 country
- UC-GENOME: Urothelial Cancer-GENOmic Analysis to iMprove Patient Outcomes and rEsearchCompletedNCT02643043Not applicable1 country
- A Study of Ramucirumab (LY3009806) Plus Docetaxel in Participants With Urothelial CancerCompletedNCT02426125Phase 323 countries
- Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the UrotheliumCompletedNCT00053209Phase 21 country
- Piritrexim in Treating Patients With Advanced Cancer of the Urinary TractCompletedNCT00002914Phase 22 countries
- Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium and Decreased Kidney FunctionCompletedNCT00005644Phase 21 country
- Two-Drug Combination Chemotherapy Compared With Four-Drug Combination Chemotherapy in Treating Patients With Advanced Cancer of the UrotheliumCompletedNCT00003376Phase 31 country
- Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder CancerCompletedNCT00004223Phase 23 countries
- Combination Chemotherapy in Treating Patients With Bladder CancerCompletedNCT00003701Phase 31 country
- Rucaparib in Patients With Locally Advanced or Metastatic Urothelial CarcinomaTerminatedNCT03397394Phase 26 countries
- Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder CancerCompletedNCT03617913Phase 21 country
- LCI-GU-URO-CRI-001: Crizotinib in Patients With c-MET or RON-Positive Metastatic Urothelial CancerTerminatedNCT02612194Phase 21 country
- Pembrolizumab and Docetaxel or Gemcitabine Hydrochloride in Treating Patients Urothelial CancerCompletedNCT02437370Phase 11 country
- Cabozantinib for Advanced Urothelial CancerCompletedNCT01688999Phase 21 country
- MRx0518 in Patients With Solid Tumours Waiting Surgical Removal of the TumourStatus unknownNCT03934827Phase 11 country
- Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial CarcinomaActive, not recruitingNCT03179943Phase 21 country
- Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary TractCompletedNCT00006111Phase 21 country
- Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney FunctionCompletedNCT00478361Phase 21 country
- Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial CancerCompletedNCT00749892Phase 21 country
- Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural EffusionsCompletedNCT00066404Phase 11 country
- Gemcitabine Hydrochloride and Eribulin Mesylate in Treating Patients With Bladder Cancer That is Advanced or Cannot Be Removed by SurgeryCompletedNCT02178241Phase 22 countries
- A Trial With Vinflunine in Patients With Metastatic Bladder Cancer and Impaired Renal FunctionCompletedNCT02665039Phase 22 countries