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Synucleinopathies clinical trials

The registry lists 38 studies for Synucleinopathies across more than 10 countries. 23 are recruiting or about to start. 5 of them are mainly about Synucleinopathies (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 4 narrower conditions too, such as Parkinson Disease: 4,867 studies, 1,176 open.

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Status

Recruiting
18
Completed
10
Enrolling by invitation
3
Status unknown
2
Active, not recruiting
2
Not yet recruiting
2

Phase

Phase 2
8
Phase 1
2
Early Phase 1
2
Phase 3
2

Where

United States
12
China
6
Italy
5
France
4
Denmark
4
Netherlands
3

Who runs them

Danish Research Centre for Magnetic Resonance (3) · Radboud University Medical Center (3) · Alterity Therapeutics (2) · University Hospital, Bordeaux (1) · SciNeuro (1) · Tianjin Medical University (1) · Fondazione Don Carlo Gnocchi Onlus (1) · Rutgers, The State University of New Jersey (1)

What is being tested here

Drugs under test in Synucleinopathies studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Adalimumab101
Donanemab101
Ambroxol111
Tenapanor101
ATH434002
Idebenone001
Rasagiline011

Coming up

1phase 3 study under way
5studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 5

Who these studies take

Of the 18 Synucleinopathies studies recruiting now, 7 (39%) set no upper age limit and 2 (11%) stop at 75 or younger. 1 (6%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (33%) take healthy volunteers.

Recruiting studies that take each age, of 18
AgeWomenMen
101 (6%)1 (6%)
187 (39%)7 (39%)
308 (44%)8 (44%)
4010 (56%)10 (56%)
5017 (94%)17 (94%)
6518 (100%)18 (100%)
7518 (100%)18 (100%)
8510 (56%)10 (56%)

Across all 38 studies, recruiting or not: 16% stop at 75 or younger and 0% at 65; 3% take children; 0% are for women only and 0% for men only; 37% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 38 of 38. search them.