Squamous Intraepithelial Lesions: all 104 studies
Page 1 of 2. Open to participants first (36), then studies with results posted, then the rest; newest registration first within each.
- Evaluating Photodynamic Therapy Used to Treat Cutaneous Squamous Cell Carcinoma in Situ (isSCC) on the Face, Upper Extremities & Trunk.RecruitingNCT07931664Phase 2
- Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot StudyRecruitingNCT07886203
- Hair Regrowth Following Partial Thickness Removal of SSCISNot yet recruitingNCT07809191Not applicable
- Papilozumib Vaginal Gel for Exocervical Mucosal Restoration in Women With Human Papillomavirus (HPV)Not yet recruitingNCT07762209Not applicable
- Evaluation of NWRD09 for HPV-16 Related Cervical HSILNot yet recruitingNCT07712692Phase 2
- Hexaminolevulinate Photodynamic Therapy (HAL-PDT) With Deferred Surgery Versus Surgery for High-grade Squamous Intraepithelial Lesions (HSIL)Not yet recruitingNCT07669363Phase 2
- Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic AbnormalitiesRecruitingNCT07572396Phase 2
- Comparison Between Liquid-Based Cytology And Molecular Screening For Detecting Precursor Lesions and Cervical CancerRecruitingNCT07480902Not applicable
- Trial to Evaluate Nonavalent HPV Vaccine as a Secondary Prevention in Patients Treated for Human Papilloma Virus Related High-grade Squamous Intraepithelial LesionsNot yet recruitingNCT07431502Phase 3
- Multicenter Prospective Non-randomized Controlled Study of Ella Photodynamic Therapy for Cervical HSIL/CIN2RecruitingNCT07306260Not applicable
- Multicenter Prospective Non-randomized Controlled Study of ALA-PDT for LSIL With HPV16/18 InfectionRecruitingNCT07306247Not applicable
- Evaluation of NWRD08 for HPV-16 and/or HPV-18 Related Cervical HSILRecruitingNCT07175662Phase 2
- NWRD09 for HPV-16 Related Cervical HSILRecruitingNCT07047989Phase 1
- Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure ProphylaxisRecruitingNCT07029152Not applicable
- CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer TrialRecruitingNCT06949800Phase 2
- Predicting Treatment Failure in HSIL Patients with Positive Margins After Conization Via Detection of PAX1 MethylationNot yet recruitingNCT06713655
- Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)RecruitingNCT06577311Phase 2
- Efficacy of Topical 85% TCA in the Treatment of LSIL After Low-grade Abnormality of Screening Test: a Randomized Controlled TrialEnrolling by invitationNCT06525870Phase 2
- A Multicenter Randomized Controlled Study of Photoelectric Detection in Cervical Cancer ScreeningNot yet recruitingNCT06491888Not applicable
- A Multicenter Real-world Study of Screening of Cervical Cancer Based on Photoelectric DetectionNot yet recruitingNCT06481930
- Role of Methylation Test Triage in HPV Positive WomenNot yet recruitingNCT06366516Not applicable
- Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated with ImiquimodRecruitingNCT06356012Phase 4
- Laser Ablation in the Treatment of High-grade Cervical LesionsNot yet recruitingNCT06333743Not applicable
- Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIVNot yet recruitingNCT06233331Phase 1
- Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative ParticipantsRecruitingNCT06206564Phase 2
- Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV InfectionRecruitingNCT06052033Not applicable
- Evaluation Of The Efficacy Of The Combination Of GLIZIGEN® Oral Solution 1/Day And Vaginal Gel 1/Night For 2 Months In Patients With Cervical Intraepithelial Neoplasia Grade 1 (LSIL/CIN-1) Caused By High-Risk Human Papillomavirus (HPV-AR)RecruitingNCT05916911Phase 4
- COrSIcA: Disease MeasurementNot yet recruitingNCT05858021
- Prognostic Study of HPV Virus Integration in Women With HSILRecruitingNCT05745597
- 5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin CancerRecruitingNCT05381597Phase 2/3
- Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV InfectionRecruitingNCT05283239
- A Multicenter Cohort Study of HPV Viral Load in Predicting the Postoperative Recurrence of HSILRecruitingNCT05282745
- Effect of HPV Integration on Prognosis of Young Women With CIN2 in ChinaRecruitingNCT05282095
- HPV Viral Load in Predicting the Prognosis of LSILRecruitingNCT05051852
- Evaluation of AHCC® for the Clearance of High Risk-HPV Infections in Chinese FemaleRecruitingNCT04633330Not applicable
- Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.RecruitingNCT02956031
- The Effectiveness of High Resolution Microendoscopy for People Living With HIVCompletedNCT04563754Phase 1/2Results posted
- REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)CompletedNCT03721978Phase 3Results posted
- VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal LesionsCompletedNCT03603808Phase 2Results posted
- VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2CompletedNCT03499795Phase 2Results posted
- Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial LesionsTerminatedNCT03197025Phase 1Results posted
- REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)CompletedNCT03185013Phase 3Results posted
- Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)CompletedNCT03180684Phase 2Results posted
- HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal LesionsTerminatedNCT03051516Phase 4Results posted
- A Clinical Trial of PepCan to Two Therapy Arms for Treating Cervical High-Grade Squamous Intraepithelial LesionsCompletedNCT02481414Phase 2Results posted
- A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial NeoplasiaCompletedNCT02189161Not applicableResults posted
- Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade LesionsCompletedNCT02135419Phase 3Results posted
- Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin LesionsCompletedNCT02059499Phase 3Results posted
- A Trial of Radiofrequency Ablation for Anal Intraepithelial Neoplasia Using the HALO Ablation SystemCompletedNCT01970787Not applicableResults posted
- Pilot Study of PDL to Treat BCC and SCCISCompletedNCT01245972Not applicableResults posted
- Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal NeoplasiaCompletedNCT01164722Phase 3Results posted
- Activating Collaborative CIS Support Via Targeted Provider MailingCompletedNCT00873288Not applicableResults posted
- Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the AnusCompletedNCT00550589Phase 2Results posted
- Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 InfectionCompletedNCT00513526Phase 2Results posted
- Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial HyperplasiaTerminatedNCT00503581Phase 2Results posted
- Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the CervixCompletedNCT00285207Phase 2Results posted
- Predictive Biomarkers for Precision Management of Pre-cancerous Cervical NeoplasiaActive, not recruitingNCT07895641
- Dual-Modality Immunotherapy for HPV Clearance (DUAL-HPV)Active, not recruitingNCT07735039Not applicable
- A Clinical Study on the Evaluation of BD114 for the Treatment HPV-16-Related Cervical HSILTerminatedNCT07170254Early Phase 1
- Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)Active, not recruitingNCT06651957
- Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSILCompletedNCT06325592
- NWRD08 DNA Plasmid for HPV-16 and/or HPV-18 Related Cervical HSILCompletedNCT06276101Phase 1
- Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC)CompletedNCT06159842Phase 2
- Primary Cervical Cancer Screening by Self-sampling HPV TestActive, not recruitingNCT05613283
- Anal HSIL Screening AlgorithmCompletedNCT05531799Not applicable
- Effect of Alpha-lipoic Acid on Regression of Low-grade Squamous Intraepithelial Lesions (LSIL)CompletedNCT05485259Not applicable
- Improving Cervical Cancer Screening in Women Living With HIV Attending Chronic Disease Clinics in Semi-rural TanzaniaCompletedNCT05256862
- Clinical Evaluation of Detection of High Risk HPV in UrineStatus unknownNCT05210348
- Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous LesionsStatus unknownNCT05170620Not applicable
- Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial NeoplasiaCompletedNCT05104099Phase 2
- ANAL PRECANCEROUS LESIONS IN HIGH-RISK PATIENTS.Status unknownNCT05060640
- A Study to Evaluate Safety, Efficacy of Intralesional Injection of STP705 in Patients With isSCCCompletedNCT04844983Phase 2
- Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence AlgorithmStatus unknownNCT04695015
- Intraoperative HPV Testing EvaluationStatus unknownNCT04190472
- Evaluation of Thioldisulfide Balance in Cervical Preinvasive LesionsCompletedNCT04177641
- Conservative Management in Patients Diagnosed With Grade 2 or Grade 3 CINStatus unknownNCT04115787
- DNA Methylation for Screening Uterine Cervical Lesions: A Case-control StudyStatus unknownNCT03961191
- DNA Methylation for Screening Uterine Cervical LesionsStatus unknownNCT03960879
- Preventing Invasive Cervical Cancer: The Importance of Expectant Management in Young Women With High-grade Pre-cancerous LesionsCompletedNCT03920800
- Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.CompletedNCT03697226Phase 1
- Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) InfectionTerminatedNCT03677960Phase 1
- E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSMStatus unknownNCT03357991
- A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal WandStatus unknownNCT03302858Phase 2
- Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) InfectionCompletedNCT03239223Phase 1
- Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) InfectionCompletedNCT03202992Phase 1
- A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.CompletedNCT02976987Phase 2
- In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer?Status unknownNCT02937155
- Validation of a Health-Related Symptom Index for Persons Diagnosed With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (HSIL)CompletedNCT02836522
- Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1)CompletedNCT02631863Phase 2
- Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSILStatus unknownNCT02576561Phase 2
- The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With MenTerminatedNCT02503111Not applicable
- Observational vs. Ablative Treatment for Low-grade Squamous Intraepithelial Lesions.CompletedNCT02331550Not applicable
- Anal Dysplasia in Patients With Inflammatory Bowel Disease and Healthy ControlsCompletedNCT01860963Not applicable
- The Effect of Probiotics on the Clearance of the Human Papillomavirus and on Cytological Lesions Caused by the VirusCompletedNCT01097356Not applicable
- Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the LipCompletedNCT00868088Phase 4
- Folic Acid Clinical Trial for the Prevention of Cervical CancerCompletedNCT00703196Phase 2
- Detecting Anal and Genital Human Papillomavirus Infection and Squamous Intraepithelial Lesions in HIV-Positive Patients Enrolled in AIDS Cancer Clinical TrialsCompletedNCT00695422
- The Effects of MBSR in Improving Immune Response to Human Papillomavirus in Patients With Cervical DysplasiaCompletedNCT00653146Not applicable
- A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL)CompletedNCT00596258Phase 2
- Assessing Drivers and Barriers to Follow-Up Screening for Anal Cancer in Men Who Have Sex With MenCompletedNCT00501306