Sclerosis: all 3,103 studies

Page 4 of 32. Open to participants first (314), then studies with results posted, then the rest; newest registration first within each.

• Optic Neuritis Differential Diagnosis StudyRecruitingNCT03370965Not applicable
• Biomarkers of Synaptic Damage in Multiple SclerosisRecruitingNCT03217396
• Circulating Biomarker for Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT03088839
• Physiological Effects of N-Acetyl Cysteine in Patients With Multiple SclerosisEnrolling by invitationNCT03032601Not applicable
• Swiss Multiple Sclerosis RegistryRecruitingNCT02980640
• Trial to Assess the Safety and Feasibility of Adoptive Cell Therapy with Autologous EBV-specific Cytotoxic T Lymphocytes (CTL) in Patients with a First Clinical Episode Highly Suggestive of Multiple SclerosisRecruitingNCT02912897Phase 1
• Tolerogenic Dendritic Cells as a Therapeutic Strategy for the Treatment of Multiple Sclerosis Patients (TOLERVIT-MS)RecruitingNCT02903537Phase 1
• Clinical Presentation and Renal Outcome of Patients With Tuberous Sclerosis Complex and/or Renal Angiomyolipoma in the Great West Region of FranceRecruitingNCT02887781
• Lorraine Registry of Multiple SclerosisRecruitingNCT02883335
• Amyotrophic Lateral Sclerosis and the Innate Immune SystemRecruitingNCT02869048
• Outpatient Hematopoietic Grafting in Multiple Sclerosis Employing Autologous Peripheral Blood Stem CellsEnrolling by invitationNCT02674217Not applicable
• IConquerMS™ - a Patient-Powered Research Network for Multiple SclerosisRecruitingNCT02486562
• Swiss Multiple Sclerosis Cohort-StudyRecruitingNCT02433028
• Complementary and Alternative Care in Multiple SclerosisRecruitingNCT01703429
• Epidural Stimulation in Multiple SclerosisCompletedNCT06019611Not applicableResults posted
• Study to Investigate the Long-term Safety of FAB122 in Patients With Amyotrophic Lateral SclerosisTerminatedNCT05866926Phase 3Results posted
• Cubii for Exercise in People With MSCompletedNCT05826431Not applicableResults posted
• A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031)TerminatedNCT05442775Phase 3Results posted
• PTNS for Female Patients Suffering From Multiple SclerosisTerminatedNCT05422625Not applicableResults posted
• Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT05237284Phase 2Results posted
• Study to Investigate the Efficacy and Safety of FAB122 (Daily Oral Edaravone) in Patients With Amyotrophic Lateral SclerosisCompletedNCT05178810Phase 3Results posted
• Natalizumab and Chronic InflammationTerminatedNCT05177718Phase 4Results posted
• Improving Prospective Memory Via TelehealthCompletedNCT05129293Not applicableResults posted
• MS Spinal Mobilisation StudyCompletedNCT05090709Not applicableResults posted
• A Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution and Repeatability of 11C-BMS-986196 After Intravenous (IV) Administration in Healthy Participants and After Repeat IV Administration in Participants With Multiple SclerosisTerminatedNCT05064436Phase 1Results posted
• PET Imaging of Cyclooxygenase in Multiple SclerosisTerminatedNCT05062083Phase 2Results posted
• A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALSTerminatedNCT05053035Phase 2Results posted
• 3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)CompletedNCT05039268Phase 2Results posted
• Safety Study to Evaluate Immune Response of Vaccines in Participants With Relapsing Forms of Multiple Sclerosis Who Receive Ozanimod Compared to Non-Pegylated Interferon (IFN)-β or No Disease Modifying TherapyCompletedNCT05028634Phase 3Results posted
• TJ-68 Clinical Trial in Patients With Amyotrophic Lateral Sclerosis (ALS) and Muscle CrampsCompletedNCT04998305Phase 1/2Results posted
• Effectiveness of Cladribine Tablets in Participants With Highly-active Relapsing Multiple Sclerosis (CAMELOT-MS)CompletedNCT04997148Results posted
• Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple SclerosisTerminatedNCT04984278Phase 3Results posted
• ALS and Airway Clearance (ALSAC) TherapyCompletedNCT04947436Not applicableResults posted
• A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT04944784Phase 3Results posted
• Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple SclerosisTerminatedNCT04925557Phase 2/3Results posted
• A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic SclerosisTerminatedNCT04915950Phase 2Results posted
• The Therapeutic Effects of Forced Aerobic Exercise in Multiple SclerosisCompletedNCT04906057Not applicableResults posted
• A Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With OfatumumabTerminatedNCT04878211Phase 4Results posted
• Ocrelizumab for Preventing Clinical Multiple Sclerosis in Individuals With Radiologically Isolated Disease.TerminatedNCT04877457Phase 4Results posted
• Exploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With OfatumumabCompletedNCT04869358Phase 4Results posted
• Apollo Device for Fatigue in Systemic SclerosisCompletedNCT04854850Not applicableResults posted
• A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease PatientsTerminatedNCT04837131Phase 2Results posted
• Geometrical Facial Deformation According to Posture in Amyotrophic Lateral SclerosisCompletedNCT04798183Results posted
• Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)CompletedNCT04792567Phase 4Results posted
• Extension to the MAGNIFY MS Trial on Mavenclad® (Magnify MS Extension)CompletedNCT04783935Phase 4Results posted
• Cognition and HRQoL in Adults With Highly-active RMS in Year 3 and 4 After Initial Mavenclad® Dose (CLARIFY MS Extension)CompletedNCT04776213Phase 4Results posted
• Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multiple SclerosisTerminatedNCT04767698Phase 2Results posted
• Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS StudyCompletedNCT04754542Results posted
• A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic SclerosisCompletedNCT04744207Phase 2Results posted
• Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisActive, not recruitingNCT04742400Phase 2Results posted
• Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic SclerosisTerminatedNCT04680975Phase 2Results posted
• A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With OfatumumabCompletedNCT04667117Phase 4Results posted
• Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple SclerosisCompletedNCT04657666Phase 3Results posted
• Effects of FT011 in Systemic SclerosisCompletedNCT04647890Phase 2Results posted
• MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT04579666Phase 2Results posted
• HFS (High-Fiber Supplement) in MS (Multiple Sclerosis)CompletedNCT04574024Phase 1/2Results posted
• Aerobic Exercise for Remyelination in Multiple SclerosisCompletedNCT04539002Not applicableResults posted
• Trial of Theracurmin for Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT04499963Phase 2Results posted
• Clinical Trial Assessing Temelimab Following Rituximab Treatment in Patients With Relapsing Forms of Multiple SclerosisCompletedNCT04480307Phase 2Results posted
• A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)TerminatedNCT04478994Phase 1Results posted
• Non-invasive Transcranial Electrical Stimulation in MSCompletedNCT04466228Not applicableResults posted
• Cerebellar tDCS and Balance Training in PwMSCompletedNCT04391023Not applicableResults posted
• Time Restricted Eating Outcomes in Multiple SclerosisCompletedNCT04389970Not applicableResults posted
• Cold Challenge With C21 in RPCompletedNCT04388176Phase 2Results posted
• Neuroproprioceptive "Facilitation, Inhibition" and Brain PlasticityCompletedNCT04355663Not applicableResults posted
• Study of Evobrutinib in Participants With RMS (evolutionRMS 2)TerminatedNCT04338061Phase 3Results posted
• Study of Evobrutinib in Participants With RMS (evolutionRMS 1)TerminatedNCT04338022Phase 3Results posted
• The Effect of a Home-based Orofacial Exercise Program on Oral Aperture of Systemic Sclerosis PatientsCompletedNCT04336475Not applicableResults posted
• Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together ProgramCompletedNCT04335279Not applicableResults posted
• Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)CompletedNCT04285346Phase 2Results posted
• Effects of Ocrelizumab on B-cell Tolerance Defect in Relapsing Multiple SclerosisCompletedNCT04261790Phase 4Results posted
• An Efficacy and Safety Study of Ravulizumab in ALS ParticipantsTerminatedNCT04248465Phase 3Results posted
• Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral SclerosisCompletedNCT04245709Phase 2Results posted
• Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple SclerosisTerminatedNCT04203498Phase 3Results posted
• Safety and Pharmacokinetics of IgPro20 and IgPro10 in Adults With Systemic Sclerosis (SSc)CompletedNCT04137224Phase 2Results posted
• Efficacy and Safety of the Biosimilar Natalizumab PB006 in Comparison to Tysabri®CompletedNCT04115488Phase 3Results posted
• Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS)CompletedNCT04098406Phase 2Results posted
• Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 3)CompletedNCT04040322Phase 3Results posted
• Study of Evobrutinib in Participants With RMSTerminatedNCT04032171Phase 3Results posted
• Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS)TerminatedNCT04032158Phase 3Results posted
• Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisCompletedNCT04025554Phase 1/2Results posted
• tDCS and Glucose Uptake in Leg MusclesCompletedNCT04016844Not applicableResults posted
• Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple SclerosisCompletedNCT04000373Not applicableResults posted
• G-EO Gait Rehabilitation Training in Progressive Multiple SclerosisCompletedNCT03980145Not applicableResults posted
• A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic SclerosisTerminatedNCT03976648Phase 2Results posted
• Long-Term Outcomes and Durability of Effect Following Treatment With Cladribine Tablets for MS (CLASSIC-MS)CompletedNCT03961204Phase 4Results posted
• Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label ExtensionTerminatedNCT03948178Phase 3Results posted
• A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)CompletedNCT03933215Results posted
• Impact of Physical Activity on Cognitive Outcomes in Youth With Pediatric-Onset Multiple Sclerosis (POMS)TerminatedNCT03933020Not applicableResults posted
• KD025 in Subjects With Diffuse Cutaneous Systemic SclerosisTerminatedNCT03919799Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric ParticipantsTerminatedNCT03870763Phase 3Results posted
• tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple SclerosisCompletedNCT03870048Not applicableResults posted
• Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 2)CompletedNCT03867097Phase 2Results posted
• Short-term B-cell Depletion in Relapsing Multiple SclerosisCompletedNCT03853746Phase 4Results posted
• MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS)Active, not recruitingNCT03846219Phase 2Results posted
• Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension TrialTerminatedNCT03836716Phase 3Results posted
• Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis ComplexCompletedNCT03826628Phase 2/3Results posted
• Aspirin for Exercise in Multiple Sclerosis (ASPIRE)CompletedNCT03824938Phase 3Results posted
• Activity and Balanced Eating to Reduce Comorbidities and Symptoms of MSTerminatedNCT03808545Not applicableResults posted
• Comparison of Robot-Assisted Gait Training and Conventional Therapy in Multiple Sclerosis PatientsCompletedNCT03801473Not applicableResults posted

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