Pulmonary Emphysema clinical trials

The registry lists 64 studies for Pulmonary Emphysema across more than 10 countries. 7 are recruiting or about to start. 39 of them are mainly about Pulmonary Emphysema (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-26.

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Status

Completed: 39
Terminated: 10
Status unknown: 7
Recruiting: 6
Enrolling by invitation: 1
Withdrawn: 1

Phase

Phase 2: 17
Phase 3: 12
Phase 1: 8
Phase 4: 4

Where

United States: 22
Germany: 14
France: 9
Israel: 8
Netherlands: 7
United Kingdom: 7

Who runs them

Aeris Therapeutics (13) · Grifols Therapeutics LLC (6) · Pulmonx Corporation (3) · Heidelberg University (3) · Royal Brompton & Harefield NHS Foundation Trust (3) · Mansoura University (2) · University Hospital, Rouen (2) · Olympus Corporation of the Americas (2)

What is being tested here

Drugs under test in Pulmonary Emphysema studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Alpha 1-Antitrypsin	1	4	4
Homo sapiens whole	0	0	1
Remestemcel-l	0	0	1
Formoterol	0	0	1
Tiotropium	0	0	1
Doxycycline	0	0	1

Coming up

2phase 3 studies under way

3studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3, phase 3 first

Sep 2027A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD) · Phase 3 · Grifols Therapeutics LLC
Jun 2027Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases · University Hospital, Grenoble
Jun 2027An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema · Pulmonx Corporation

Who these studies take

Of the 6 Pulmonary Emphysema studies recruiting now, 3 (50%) set no upper age limit and 1 (17%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (17%) take healthy volunteers.

Recruiting studies that take each age, of 6
Age	Women	Men
10	0 (0%)	0 (0%)
18	4 (67%)	4 (67%)
30	4 (67%)	4 (67%)
40	6 (100%)	6 (100%)
50	6 (100%)	6 (100%)
65	6 (100%)	6 (100%)
75	6 (100%)	6 (100%)
85	3 (50%)	3 (50%)

Across all 64 studies, recruiting or not: 16% stop at 75 or younger and 3% at 65; 3% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 50 of 64. Browse all 64 → or search them.