Prurigo clinical trials
The registry lists 38 studies for Prurigo across more than 10 countries. 10 are recruiting or about to start. 36 of them are mainly about Prurigo (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
Incyte Corporation (6) · Galderma R&D (6) · Sanofi (3) · Trevi Therapeutics (3) · Celldex Therapeutics (2) · Shanghai Mabgeek Biotech.Co.Ltd (1) · Amgen (1) · Medical University of Graz (1)
What is being tested here
Drugs under test in Prurigo studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Lebrikizumab | 1 | 0 | 1 |
| Ruxolitinib | 0 | 2 | 2 |
| Nalbuphine | 0 | 2 | 2 |
| Nemolizumab | 0 | 2 | 2 |
| Dapsone Gel | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Oct 2027A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo Nodularis · Phase 3 · Sanofi
- Mar 2027Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo Nodularis · Beijing InnoCare Pharma Tech Co., Ltd.
- Aug 2027A Study to Evaluate the Efficacy and Safety of AK139 in Patients With Prurigo Nodularis. · Akeso
- Nov 2027Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults · Galderma R&D
Who these studies take
Of the 7 Prurigo studies recruiting now, 4 (57%) set no upper age limit and 2 (29%) stop at 75 or younger. 2 (29%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (29%) | 2 (29%) |
| 18 | 6 (86%) | 6 (86%) |
| 30 | 6 (86%) | 6 (86%) |
| 40 | 6 (86%) | 6 (86%) |
| 50 | 6 (86%) | 6 (86%) |
| 65 | 6 (86%) | 6 (86%) |
| 75 | 6 (86%) | 6 (86%) |
| 85 | 4 (57%) | 4 (57%) |
Across all 38 studies, recruiting or not: 37% stop at 75 or younger and 8% at 65; 5% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 38 of 38. search them.
- A Study to Evaluate the Efficacy and Safety of AK139 in Patients With Prurigo Nodularis.Not yet recruitingNCT07883213Phase 2
- A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo NodularisRecruitingNCT06293053Phase 31 country
- Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo NodularisRecruitingNCT07236099Phase 25 countries
- Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in AdultsRecruitingNCT069886182 countries
- Efficacy and Speed of Response of Lebrikizumab in High-Burden Prurigo Nodularis PatientsNot yet recruitingNCT07620561Phase 21 country
- Clinical Study of the Efficacy and Safety of SHR-1819 Injection in Adult Patients With Prurigo NodularisRecruitingNCT06554509Phase 2/31 country
- Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo NodularisRecruitingNCT072764251 country
- Phase III Clinical Study of MG-K10 Humanized Mab Injection in Subjects With Prurigo NodularisRecruitingNCT06779136Phase 31 country
- China Type II Inflammatory Skin Disease Clinical Research and Standardized Diagnosis and Treatment ProjectRecruitingNCT053168051 country
- A Randomized, Double-blinded, Self-controlled Clinical Study of Intralesional Injection of 5-fluorouracil Plus Triamcinolone for the Treatment of Refractory Nodular PrurigoNot yet recruitingNCT06524323Phase 31 country
- A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)CompletedNCT05764161Phase 313 countries
- Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational StudyCompletedNCT059913236 countries
- A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)CompletedNCT05755438Phase 311 countries
- A Study of Barzolvolimab in Patients With Prurigo NodularisActive, not recruitingNCT06366750Phase 26 countries
- A Non-interventional Study to Describe the Dupilumab Long-term Treatment, Safety and Patient Reported Outcomes in Chronic Nodular Prurigo (Prurigo Nodularis) in Clinical RoutineActive, not recruitingNCT060876271 country
- A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo NodularisTerminatedNCT06527404Phase 330 countries
- Study on the Treatment of Prurigo Nodularis With Stapokibart InjectionCompletedNCT06424470Phase 31 country
- A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)Active, not recruitingNCT06516952Phase 312 countries
- Upadacitinib for Prurigo NodularisTerminatedNCT06773403Phase 41 country
- A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)Active, not recruitingNCT06516965Phase 311 countries
- A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)Active, not recruitingNCT04204616Phase 316 countries
- A Study to Evaluate the Safety and Tolerability of Maximal Use Ruxolitinib CreamCompletedNCT06213831Phase 11 country
- A Study to Evaluate the Efficacy and Safety of INCB054707 in Participants With Prurigo NodularisCompletedNCT05061693Phase 26 countries
- PRISM Study-Pruritus Relief Through Itch Scratch ModulationCompletedNCT03497975Phase 2/35 countries
- Open Label Extension Study of Nalbuphine HCl ER in Patients With Prurigo NodularisCompletedNCT02174432Phase 2/31 country
- Study of Nalbuphine HCl ER Tablets in Patients With Prurigo NodularisCompletedNCT02174419Phase 2/33 countries
- A Study to Evaluate the Durability of Response and Safety of Nemolizumab for 24 Weeks in Participants With Prurigo NodularisCompletedNCT05052983Phase 37 countries
- A Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)CompletedNCT04501679Phase 39 countries
- Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)CompletedNCT04501666Phase 310 countries
- Benralizumab in Chronic Prurigo - Investigating Clinical Efficacy (BICPIC)WithdrawnNCT05528913Phase 21 country
- A Study of CDX-0159 in Patients With Prurigo NodularisCompletedNCT04944862Phase 13 countries
- Safety and Efficacy of Nemolizumab in PNCompletedNCT03181503Phase 24 countries
- Apremilast as Anti-pruritic Treatment in Patients With Prurigo NodularisStatus unknownNCT03576287Phase 1/21 country
- Mechanisms of Action of Photo(Chemo)Therapy in Skin DiseasesStatus unknownNCT03340155Not applicable1 country
- Safety and Efficacy of CC-10004 for Prurigo NodularisCompletedNCT00869089Phase 21 country
- Dapsone Prurigo StudyStatus unknownNCT01870050Not applicable1 country
- Evaluation of the Antipruritic Effect of Elidel (Pimecrolimus) in Non-atopic Pruritic DiseaseCompletedNCT00507832Phase 21 country
- Effectiveness of the Selective Serotonin Reuptake Inhibitor,Citalopram (Cipralex), in Prurigo NodularisStatus unknownNCT00532519Not applicable1 country