Prolonged Grief Disorder clinical trials
The registry lists 39 studies for Prolonged Grief Disorder across more than 10 countries. 14 are recruiting or about to start. 31 of them are mainly about Prolonged Grief Disorder (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-20.
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Who runs them
ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida (2) · Uppsala University (2) · Universitat Jaume I (2) · Medical College of Wisconsin (2) · Columbia University (2) · University of Aarhus (2) · Rigshospitalet, Denmark (2) · University of South Florida (1)
What is being tested here
Drugs under test in Prolonged Grief Disorder studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Psilocybin | 1 | 0 | 1 |
| Oxytocin | 0 | 0 | 1 |
| Naltrexone | 0 | 0 | 1 |
| Dexmedetomidine | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Nov 2026Technology-supported Interventions for Prolonged Grief Disorder (PGD) · Universitat Jaume I
- Dec 2026Iyengar Yoga for Prolonged Grief Disorder · Medical College of Wisconsin
- Dec 2026F-PGT - Prolonged Grief Treatment for Families Affected by Suicide · University of Pittsburgh
- Jan 2027Prolonged Grief Disorder (PGD) Diagnosis in Older Adults: Physicians' Knowledge and Practice · Ruppin Acdemic Center
- Jun 2027A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency Department · Assistance Publique - Hôpitaux de Paris
- Jun 2027Transcranial Magnetic Stimulation to Treat Prolonged Grief Disorder · Bruyère Health Research Institute.
- Jul 2027A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT · Uppsala University
- Aug 2027Psilocybin for Prolonged Grief Disorder · University of Virginia
Who these studies take
Of the 9 Prolonged Grief Disorder studies recruiting now, 7 (78%) set no upper age limit and 2 (22%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (44%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 9 (100%) | 9 (100%) |
| 30 | 9 (100%) | 9 (100%) |
| 40 | 9 (100%) | 9 (100%) |
| 50 | 9 (100%) | 9 (100%) |
| 65 | 8 (89%) | 8 (89%) |
| 75 | 7 (78%) | 7 (78%) |
| 85 | 7 (78%) | 7 (78%) |
Across all 39 studies, recruiting or not: 23% stop at 75 or younger and 21% at 65; 10% take children; 3% are for women only and 0% for men only; 31% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Prolonged Grief Disorder studies take
Of 26 interventional studies with no phase under Prolonged Grief Disorder, half reached primary completion within 25 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 25 mo8–57 · 26 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 39 of 39. search them.
- Technology-supported Interventions for Prolonged Grief Disorder (PGD)RecruitingNCT06932120Not applicable1 country
- Mechanisms Underlying Late-Life Prolonged Grief DisorderNot yet recruitingNCT07738133Not applicable1 country
- Emotion-Focused Therapy in the Treatment of Prolonged Grief DisorderRecruitingNCT07207512Not applicable1 country
- A Multifaceted Intervention Strategy for Relatives of End-of-life Patients in the Emergency DepartmentRecruitingNCT06733974Not applicable1 country
- F-PGT - Prolonged Grief Treatment for Families Affected by SuicideEnrolling by invitationNCT07318090Not applicable1 country
- Transcranial Magnetic Stimulation to Treat Prolonged Grief DisorderRecruitingNCT06953596Not applicable1 country
- Psilocybin for Prolonged Grief DisorderRecruitingNCT06724289Early Phase 11 country
- Prolonged Grief Disorder (PGD) Diagnosis in Older Adults: Physicians' Knowledge and PracticeNot yet recruitingNCT07487233Not applicable
- Understanding and Responding to Grief-Related Needs: A Differentiated Community ApproachNot yet recruitingNCT07433101Not applicable1 country
- Adolescent Suicide Loss Survivors Grief Intervention GroupNot yet recruitingNCT07151092Not applicable
- Families Left BehindRecruitingNCT06854757Not applicable1 country
- Coping After Loss Through Mindfulness in Adults With Prolonged Grief DisorderRecruitingNCT06017765Not applicable1 country
- A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCTRecruitingNCT06667674Not applicable1 country
- Empower-Grief: A Study on a Selective Intervention to Prevent Prolonged Grief DisorderRecruitingNCT06270381Not applicable1 country
- Iyengar Yoga for Prolonged Grief DisorderActive, not recruitingNCT05026827Not applicable1 country
- EMDR Grief Protocol for Traumatic Grief After Earthquake-Related LossCompletedNCT07776769Not applicable1 country
- Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and EvacuationWithdrawnNCT07537894Phase 2/31 country
- P-CRP for Recent-Onset Severe TraumaCompletedNCT07360990Not applicable1 country
- Effects of the Integrated Grief Therapy on Psychological Resilience, Post-Traumatic Growth, Traumatic Stress, and Grief Processes in Earthquake SurvivorsActive, not recruitingNCT07641270Not applicable1 country
- Diagnostic Tools for Identifying Prolonged GriefCompletedNCT053651391 country
- Cognitive Behavioural Therapy for Complicated Grief Reactions in Old AgeCompletedNCT04694807Not applicable1 country
- Oxytocin and Approach-avoid in GriefCompletedNCT04505904Not applicable1 country
- Feasibility and Efficacy of Individual SH+ InterventionCompletedNCT06091540Not applicable1 country
- Naltrexone Treatment for Prolonged Grief Disorder (PGD)TerminatedNCT04547985Phase 41 country
- Web Based Patient Tutorial on Prolonged GriefCompletedNCT05575817Not applicable1 country
- Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive CareCompletedNCT04409821Not applicable1 country
- LIVIA 2.0 : A RCT Of Two French Internet Intervention For Adults Struggling With Prolonged Grief SymptomsCompletedNCT05219760Not applicable1 country
- My Grief - an App for Parents With Prolonged Grief After Losing a Child to CancerCompletedNCT04552717Not applicable1 country
- Web Based Therapist Tutorial on Prolonged GriefCompletedNCT05121792Not applicable1 country
- Iwankapiya-Healing: Historical Trauma Practice and Group IPT for American IndiansCompletedNCT02124694Not applicable1 country
- Systematic Support for Relatives of Palliative Care PatientsStatus unknownNCT05274841Not applicable1 country
- An Internet-based Self Applied Treatment Program for Prolonged Grief Disorder (PGD)Status unknownNCT04462146Not applicable1 country
- Treatment of Prolonged Grief Disorder in Combat VeteransCompletedNCT02283333Not applicable1 country
- Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)Status unknownNCT04121884Not applicable1 country
- Measurement and Assessment of Prolonged Grief Disorder in AsiaWithdrawnNCT035689551 country
- Pilot Study of Behavioral Activation for Prolonged GriefCompletedNCT01556048Phase 11 country
- Prolonged Grief and Suicide Among VeteransWithdrawnNCT012470251 country
- A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan GenocideStatus unknownNCT00553956Phase 11 country
- Randomized Controlled Trial of the Effectiveness of Group Treatment With War-Exposed Bosnian AdolescentsCompletedNCT00480480Not applicable