Precursor B-Cell Lymphoblastic Leukemia-Lymphoma clinical trials
The registry lists 38 studies for Precursor B-Cell Lymphoblastic Leukemia-Lymphoma across more than 10 countries. 16 are recruiting or about to start. 14 of them are mainly about Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
Get an email when these change. Save the Precursor B-Cell Lymphoblastic Leukemia-Lymphoma studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Princess Maxima Center for Pediatric Oncology (5) · Children's Oncology Group (3) · University of Washington (3) · First Affiliated Hospital of Zhejiang University (3) · Medical College of Wisconsin (2) · Seagen Inc. (2) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · Shanghai Children's Medical Center (1)
What is being tested here
Drugs under test in Precursor B-Cell Lymphoblastic Leukemia-Lymphoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cyclophosphamide | 4 | 2 | 8 |
| Blinatumomab | 4 | 3 | 6 |
| Venetoclax | 4 | 0 | 6 |
| Inotuzumab Ozogamicin | 3 | 1 | 7 |
| Cytarabine | 3 | 2 | 5 |
| Dexamethasone | 3 | 0 | 4 |
| Doxorubicin | 1 | 2 | 4 |
| Thioguanine | 1 | 3 | 3 |
| Fludarabine | 1 | 0 | 1 |
| BEBT-908 | 1 | 0 | 1 |
Drug classes tested here Antimetabolites 5 open · Corticosteroids 3 open · Tyrosine kinase inhibitors (TKIs) 3 open · Antimitotic agents 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10, phase 3 first
- Jan 2027Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL · Phase 3 · National University of Malaysia
- Sep 2027A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia · Phase 3 · National Cancer Institute (NCI)
- Oct 2027A Study of Injectable BLB101 and Blincyto® in Adult Participants With R/R CD19+ B-ALL · Phase 3 · Institute of Hematology & Blood Diseases Hospital, China
- Nov 2026Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia · M.D. Anderson Cancer Center
- Dec 2026CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+ · Zhu Xiaofan
- Dec 2026A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Dec 2026Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia · Children's Oncology Group
- Dec 2026Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL · Peking University People's Hospital
- Apr 2027Comparing Inotuzumab Combined With Low Intensity Chemotherapy Plus Blinatumomab to Usual Chemotherapy Plus Blinatumomab in Older Adults With CD22+ B-cell Acute Lymphoblastic Leukemia · Alliance for Clinical Trials in Oncology
- Jun 2027Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/Leukemia · University of Washington
Who these studies take
Of the 12 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma studies recruiting now, 4 (33%) set no upper age limit and 8 (67%) stop at 75 or younger. 9 (75%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (42%) | 5 (42%) |
| 18 | 11 (92%) | 11 (92%) |
| 30 | 6 (50%) | 6 (50%) |
| 40 | 7 (58%) | 7 (58%) |
| 50 | 7 (58%) | 7 (58%) |
| 65 | 6 (50%) | 6 (50%) |
| 75 | 4 (33%) | 4 (33%) |
| 85 | 4 (33%) | 4 (33%) |
Across all 38 studies, recruiting or not: 55% stop at 75 or younger and 42% at 65; 58% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 38 of 38. search them.
- Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLyRecruitingNCT03959085Phase 35 countries
- Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/LeukemiaRecruitingNCT06710418Not applicable1 country
- Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic LymphomaNot yet recruitingNCT07758673Phase 11 country
- A Study of Injectable BLB101 and Blincyto® in Adult Participants With R/R CD19+ B-ALLNot yet recruitingNCT07723911Phase 3
- Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic LeukemiaRecruitingNCT02877303Phase 21 country
- Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALLRecruitingNCT06880913Phase 1/21 country
- BEBT-908 Plus Chemotherapy Treatment for CR MRD-Positive MEF2D-Rearranged and Pre-B Acute Lymphoblastic Leukemia PatientsNot yet recruitingNCT07301138Phase 21 country
- HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological MalignanciesNot yet recruitingNCT07175415Phase 1/2
- HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological MalignanciesRecruitingNCT05751044Phase 1/214 countries
- HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological MalignanciesRecruitingNCT05658640Phase 1/215 countries
- HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological MalignanciesRecruitingNCT05745714Phase 1/214 countries
- Intravenous Autologous CD19 CAR-T Cells for R/R B-ALLRecruitingNCT03937544Phase 2/31 country
- Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALLRecruitingNCT06754267Phase 21 country
- Blinatumomab Plus Reduced-dose Chemotherapy in Treating B-ALLRecruitingNCT06742515Phase 21 country
- Blinatumomab Plus Venetoclax Sequenced With Inotuzumab Ozogamicin in Treating B-ALLRecruitingNCT06554626Phase 21 country
- CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+RecruitingNCT06355739Not applicable1 country
- A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic LeukemiaActive, not recruitingNCT03914625Phase 35 countries
- A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission MaintenanceActive, not recruitingNCT03114865Phase 1/21 country
- Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic LeukemiaActive, not recruitingNCT03504644Phase 1/22 countries
- Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic LeukemiaActive, not recruitingNCT02981628Phase 22 countries
- Comparing Inotuzumab Combined With Low Intensity Chemotherapy Plus Blinatumomab to Usual Chemotherapy Plus Blinatumomab in Older Adults With CD22+ B-cell Acute Lymphoblastic LeukemiaActive, not recruitingNCT05303792Phase 22 countries
- Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic LymphomaCompletedNCT01190930Phase 37 countries
- FT819 in Subjects With B-cell MalignanciesActive, not recruitingNCT04629729Phase 11 country
- HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological MalignanciesWithdrawnNCT05740449Phase 1/21 country
- A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible PatientsCompletedNCT03677596Phase 48 countries
- Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic LeukemiaCompletedNCT03991884Phase 11 country
- Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)CompletedNCT00849147Phase 21 country
- Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604)CompletedNCT00864227Phase 21 country
- A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALLTerminatedNCT01483690Phase 1/22 countries
- Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaWithdrawnNCT02538926Phase 21 country
- Acute Lymphoblastic Leukemia Registry at Asan Medical CenterTerminatedNCT017616821 country
- The Effect of Chemotherapy on Regulatory T CellsStatus unknownNCT03413046
- MB-CART19.1 in Patients With R/R ALLStatus unknownNCT03321123Phase 2
- A Safety Study of SGN-CD19A for B-Cell LymphomaCompletedNCT01786135Phase 11 country
- Repeat-dose Study of Lenalidomide (Revlimid ®) Plus Dexamethasone in Patients With Lymphoblastic LeukemiaCompletedNCT01116193Phase 21 country
- A Safety Study of SGN-CD19A for Leukemia and LymphomaCompletedNCT01786096Phase 11 country
- Nilotinib With Chemotherapy for the Treatment of Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaTerminatedNCT00905398Phase 1/2
- Coproporphyrine Isomers and Methotrexate EliminationCompletedNCT008224321 country