Pilonidal Sinus clinical trials
The registry lists 109 studies for Pilonidal Sinus across more than 10 countries. 32 are recruiting or about to start. 101 of them are mainly about Pilonidal Sinus (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-07.
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Who runs them
Mansoura University (7) · Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital (4) · GCS Ramsay Santé pour l'Enseignement et la Recherche (4) · Zagazig University (4) · Medical Park Gaziantep Hospital (3) · Bezmialem Vakif University (2) · Centre Hospitalier Departemental Vendee (2) · Federico II University (2)
What is being tested here
Drugs under test in Pilonidal Sinus studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Clascoterone | 1 | 0 | 1 |
| Phenol | 0 | 0 | 1 |
| Clonidine | 0 | 0 | 1 |
| Metronidazole | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026ENVELOP: Wound Care Following Pilonidal Sinus Surgery · Royal College of Surgeons, Ireland
- Jan 2027Bascom Cleft Lift for Primary Wound Healing in Complex and Recurrent Sacrococcygeal Pilonidal Sinus Disease · Albert Schweitzer Ziekenhuis, Netherlands
- May 2027Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone) · dr. IJM Han-Geurts
- Sep 2027Laser Coagulation of Pilonidal Sinus With/Without Intraoperative Ultrasound Control · State Scientific Centre of Coloproctology, Russian Federation
- Sep 2027VAAPS Combined With Loose Seton Drainage for Postoperative Self-Care: A Prospective Single-Arm Cohort Study · Peking University People's Hospital
Who these studies take
Of the 22 Pilonidal Sinus studies recruiting now, 15 (68%) set no upper age limit and 6 (27%) stop at 75 or younger. 7 (32%) take children under 18. 1 (5%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (18%) | 4 (18%) |
| 18 | 22 (100%) | 21 (95%) |
| 30 | 20 (91%) | 19 (86%) |
| 40 | 19 (86%) | 18 (82%) |
| 50 | 19 (86%) | 18 (82%) |
| 65 | 19 (86%) | 18 (82%) |
| 75 | 16 (73%) | 15 (68%) |
| 85 | 16 (73%) | 15 (68%) |
Across all 109 studies, recruiting or not: 39% stop at 75 or younger and 31% at 65; 42% take children; 1% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pilonidal Sinus studies take
Of 35 interventional studies with no phase under Pilonidal Sinus, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo11–35 · 35 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 109. Browse all 109 → or search them.
- VAAPS Combined With Loose Seton Drainage for Postoperative Self-Care: A Prospective Single-Arm Cohort StudyRecruitingNCT07855107Not applicable1 country
- ENVELOP: Wound Care Following Pilonidal Sinus SurgeryRecruitingNCT06647290Not applicable1 country
- Laser Coagulation of Pilonidal Sinus With/Without Intraoperative Ultrasound ControlNot yet recruitingNCT07829315Not applicable
- Urinary Bladder Matrix (UBM) RegistryNot yet recruitingNCT07805798
- Sacral Erector Spinae Plane Block in Pilonidal Sinus SurgeryRecruitingNCT07534488Not applicable1 country
- Phenol or Laser: Best Minimally Invasive Treatment for Pilonidal Sinus?RecruitingNCT067211691 country
- Myriad™ Augmented Soft Tissue Reconstruction RegistryRecruitingNCT052439661 country
- Cost-utility Analysis of the Use of a Laser Fiber in the Management of Non-abscessed Pilonidal CystNot yet recruitingNCT07652099Not applicable1 country
- Intraoperative Wound Irrigation for Pilonidal DiseaseRecruitingNCT07417202Not applicable1 country
- Prospective Study in Laser Treatment of Pilonidal CystsRecruitingNCT073146321 country
- Effectiveness of Different Surgical Techniques for Curative Treatment of Pilonidal Sinus Disease in the Pediatric PopulationNot yet recruitingNCT07470294
- Topical Anti-Androgens in Pilonidal Sinus DiseaseRecruitingNCT06286397Phase 21 country
- Silac Versus Phenol for the Treatment of Pilonidal Sinus Disease: A Randomized Controlled TrialNot yet recruitingNCT07420452Not applicable1 country
- The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal SinusRecruitingNCT07408414Not applicable1 country
- Factors Affecting Wound Dehiscence in Pilonidal Sinus Surgery (ORIPIS)RecruitingNCT073707141 country
- SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.Not yet recruitingNCT07260643
- Evaluation of the Healing of the Pilonidal Cyst After 1940 nm Laser TreatmentRecruitingNCT072695481 country
- Bascom Cleft Lift for Primary Wound Healing in Complex and Recurrent Sacrococcygeal Pilonidal Sinus DiseaseRecruitingNCT066832741 country
- Evaluation of the Impact of Pilonidal Cyst Recurrence on Quality of Life in Patients Previously Treated With Conventional Surgery or Laser TherapyRecruitingNCT071941611 country
- Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal SinusRecruitingNCT07023952Not applicable1 country
- Comparison of Pit Picking, Phenol and Combined Pit Picking and Phenol Applications in Pilonidal Sinus TreatmentRecruitingNCT065174721 country
- Outcomes of Karydakis, Primary Closure, and Pit Picking Methods in the Treatment of Pilonidal Sinus: A Prospective Study in WomenRecruitingNCT065184991 country
- Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA Trial (Laser And Pit-picking OR Pit-picking Alone)Not yet recruitingNCT06140199Not applicable
- The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus DiseaseRecruitingNCT06324656Not applicable1 country
- Pilonidal Sinus DiseaseRecruitingNCT06508086Not applicable1 country
- Bacterial Ecology of Pilonidal CystsRecruitingNCT055138851 country
- The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in ChildrenRecruitingNCT06391307Not applicable1 country
- Rhomboid Flap vs. Deep Suturing in Recurrent Pilonidal SinusNot yet recruitingNCT06152952
- Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative AnalgesiaRecruitingNCT05990569Not applicable1 country
- Karydakis Flap Versus Burow's Triangle Advancement Flap in the Surgery of Sacrococcygeal Pilonidal Sinus DiseaseRecruitingNCT05289297Not applicable1 country
- Comparative Study Between Wide Local Excision and Minimal Excision of Pilonidal SinusNot yet recruitingNCT06021392
- Patients' Quality of Life After Pilonidal Cyst Operations.Enrolling by invitationNCT05982028Not applicable1 country
- Pediatric Pilonidal Sinus Surgical TreatmentCompletedNCT07369921Not applicable1 country
- Comparison of Primary Closure Vs Open Wound in Pilonidal Sinus Excision.CompletedNCT07798752Not applicable1 country
- Comparison of the Effectiveness of the Simple Puncture Compared to the Incision of an Abscess on the piLOnidal SinusTerminatedNCT06378918Not applicable1 country
- The Role of Platelet-rich Plasma Local Injection as Treatment in Improvement of Pilonidal Sinus Surgery OutcomesCompletedNCT07567586Not applicable1 country
- Sorbact TM: Effect of a Microbial Binding Dressing on Wound Healing After Pilonidal Sinus ExcisionCompletedNCT02011802Not applicable1 country
- Primary Closure vs Open Technique for Pilonidal SinusCompletedNCT07311707Not applicable1 country
- Karydakis Versus Limberg Flap for the Management of Primary Sacrococcygeal Pilonidal SinusCompletedNCT072715371 country
- Interest in the Use of Dressings With Honey for Wound Healing After Excision of Pilonidal CystCompletedNCT02485860Phase 41 country
- The Outcomes of Keystone Perforator Island Flap Versus Lay Open in Re-recurrent Pilonidal Sinus DiseaseCompletedNCT06741449Not applicable1 country
- Laser and Phenol Treatment for Pilonidal SinusActive, not recruitingNCT070228991 country
- Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus SurgeryCompletedNCT06459739Not applicable1 country
- Phenol and Silver Nitrate Application in Pilonidal SinusCompletedNCT04560049Phase 41 country
- Comparative Analysis of Hypobaric Versus Hyperbaric Bupivacaine for Spinal Anesthesia in Day-Case Anorectal SurgeryCompletedNCT054098201 country
- Treatment of Pilonidal Cyst With Holmium LaserCompletedNCT055138981 country
- Radiofrequency Treatment for Pilonidal Disease : Safety of Use, Efficacy and Patient Satisfaction at 6 MonthsActive, not recruitingNCT05855733Not applicable1 country
- Umblical Pilonidal Sinus EvaluationCompletedNCT04856605
- Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus SurgeryCompletedNCT06206330Not applicable1 country
- A Promising Minimally Invasive Surgical Technique for the Treatment of Infected Pilonidal SinusCompletedNCT059005181 country