Periapical Periodontitis: all 256 studies
Page 2 of 3. Open to participants first (65), then studies with results posted, then the rest; newest registration first within each.
- CGF-Enhanced Autologous Pulp Transplantation in Mature Necrotic TeethCompletedNCT07314866Not applicable
- Evaluation of Postoperative Pain and Lesion Healing in Periapical Lesion-Affected Teeth Obturated With Different Root Canal SealersActive, not recruitingNCT07307807Not applicable
- Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical PeriodontitisCompletedNCT07292363
- PRF and CGF Scaffolds With EDTA in RegenerationCompletedNCT07265804Not applicable
- N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical PeriodontitisActive, not recruitingNCT07262554Phase 2
- Comparison of Frequency of Calcium Hydroxide Mixed With 0.2% Chlorhexidine Versus Saline as Intracanal Medicament in Periapical Periodontitis-A Randomized Controlled TrialActive, not recruitingNCT07252258Not applicable
- Comparison of Sonic and Ultrasonic Activation on Healing of Apical PeriodontitisCompletedNCT07249450Not applicable
- Examination of the Effect of Nd:YAG Laser on Oxidative Stress and Matrix Metalloproteinase-9 in Teeth With Apical PeriodontitisCompletedNCT07243353
- The Success of Root Canal Treatments Performed Using Two Different Intracanal MedicamentsActive, not recruitingNCT07210177Not applicable
- Healing After Endodontic Microsurgery Using a Rotary Bur Versus Piezoelectric Unit for Osteotomy and Root ResectionActive, not recruitingNCT07197658Not applicable
- The Effect of Using Octenidine Hydrochloride as a Final Irrigation Solution on Teeth With Asymptomatic Apical Periodontitis on Postoperative Pain and Treatment Success: A Prospective Randomized Clinical StudyCompletedNCT07173725Not applicable
- Effect of Ozone Use in Intracanal Irrigation on Oxidative Stress Level in Teeth With Asymptomatic Apical PeriodontitisActive, not recruitingNCT07171762Not applicable
- Post-operative Pain After Different Irrigation and Disinfection Methods in Single-rooted TeethCompletedNCT07170098Not applicable
- Effect of EDDY Sonic Irrigation on Root Canal Microbiota and Pain in Asymptomatic Apical PeriodontitisCompletedNCT07120126Not applicable
- Evaluation of Different Root Canal Irrigation TechniquesCompletedNCT07106320Not applicable
- Evaluation of Different Root Canal Obturation TechniquesCompletedNCT07106307Not applicable
- Healing Outcomes Following Hydraulic Condensation With a Bioactive Bioceramic Sealer in Root Canal TreatmentCompletedNCT07075354Not applicable
- Comparison of LSTR and Pulpectomy in Primary Molars of Pediatric Patients (LSTR-PULP)CompletedNCT07026435Not applicable
- Effect of Valaciclovir on Inter-Appointment Pain in Endodontic Treatment of Necrotic TeethCompletedNCT07014397Not applicable
- Efficacy of Apical Preparation With Passive Ultrasonic Irrigation in Reducing Intracanal BacteriaCompletedNCT07005219Not applicable
- Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root CanalActive, not recruitingNCT06949176Not applicable
- Photodynamic Therapy in Root Canal Treatment of T2DM Patients: Microbiome Analysis Via Next-Gen SequencingCompletedNCT06931678Not applicable
- Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled TrialCompletedNCT06886438Not applicable
- The Role of Root Canal Treatment in Alleviating Endodontic Pain-Induced Asymmetry and Restoring Muscle BalanceCompletedNCT06853028
- Lesion Healing After Regenerative Endodontic TreatmentCompletedNCT06843850Not applicable
- Chlorhexidine Versus N-Asetil Sistein Irrigation in Mandibular Molar Teeth with Chronic Apical PeriodontitisCompletedNCT06834711Not applicable
- Effect of Use of Calcium Hydroxide and Metformin Intracanal Medicament After NSRCTCompletedNCT06766201Phase 2/3
- Interleukin 8 and10 Levels Changes in Teeth With Necrotic Pulp and Apical PeriodontitisCompletedNCT06713174Not applicable
- Comparison of Post-operative Pain After Use of Endo-activator and Conventional Irrigation During Endodontic Treatment in Symptomatic Periapical PeriodontitisCompletedNCT06668662Not applicable
- Effect of Cryotherapy and Laser Application on Post-Operative Pain in Single Visit Endodontically Treated Symptomatic Apical Periodontitis CasesCompletedNCT06657664Not applicable
- Clinical Efficacy of Novel Jasminum-based Calcium Hydroxide MedicamentCompletedNCT06653608Not applicable
- Effect of Targeted Endodontic Microsurgery on Quality of Life and Healing on Mandibular MolarsCompletedNCT06643676Not applicable
- The Effect of Antimicrobial Photodynamic Therapy on the Success of Root Canal TreatmentCompletedNCT06634745Not applicable
- The Efficacy of Two Different Irrigation Methods on PGE2, NO and IL-6 LevelsCompletedNCT06629545Not applicable
- Antibacterial Effect of NaOCl With Etidronic Acid in Apical Periodontitis TreatmentCompletedNCT06597825Not applicable
- Apical Periodontitis and Mental HealthCompletedNCT06589076
- Comparative Analysis of Photodynamic Therapy on Periapical HealingCompletedNCT06553144Not applicable
- Postoperative Pain After Conservative Root Canal PreparationCompletedNCT06545773Not applicable
- Sclerostin Regulation in Apical Periodontitis Lesions in Apical Periodontitis LesionsCompletedNCT06512103
- The Impact Of Different Final Irrigation Activation Techniques On Postoperative PainCompletedNCT06501703Not applicable
- Periapical Healing in Response to Endodontically Treated Teeth With Different Sealing CementActive, not recruitingNCT06482593Phase 4
- Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not?Active, not recruitingNCT06447519Not applicable
- Association Between Apical Periodontitis and Psoriasis VulgarisCompletedNCT06436339
- Influence of Sonic Activation of Root Sealers on Post-Operative PainCompletedNCT06403293Not applicable
- Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic TeethCompletedNCT06357481Not applicable
- The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment SuccessCompletedNCT06339905Not applicable
- Premixed Bioceramic Putty as an Apical Plug in Immature Anterior Permanent TeethCompletedNCT06322979Not applicable
- hsCRP & CH Indices in Patients With Coronary Artery Disease With and Without Apical PeriodontitisActive, not recruitingNCT06270693Not applicable
- Outcome of NSRCT Versus VPT in Management of Teeth with Symptomatic Irreversible Pulpitis Associated with Apical PeriodontitisActive, not recruitingNCT06226870Not applicable
- Effectiveness of Different Obturation TechniquesCompletedNCT06226740Not applicable
- Outcome of Regenerative Endodontic Procedure and Root Canal Treatment for the Management of Apical PeriodontitisActive, not recruitingNCT06179433Not applicable
- "Postoperative Pain Following Laser-Assisted Root Canal Treatment: A Randomized Clinical Trial"CompletedNCT06129643Phase 2
- The Effect of Intra Oral Cryotherapy in Patients With Symptomatic Apical PeriodontitisCompletedNCT06082479Not applicable
- Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled TrialCompletedNCT06081335Not applicable
- Effect of Lifestyle on Caries and Apical PeriodontitisCompletedNCT06072742
- The Importance of Prostaglandin and Nitric Oxide Synthesis in Apical PeriodontitisCompletedNCT06023901Not applicable
- Relationship Apical Periodontitis and the Main Bacterial Species in the Oral MicrobiotaCompletedNCT05857436Not applicable
- Evaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular SurgeryCompletedNCT05847647Not applicable
- Effect of Smoking on Periapical Healing After NSRCTCompletedNCT05799937
- Association Between Apical Periodontitis and Atherosclerotic Cardiovascular DiseasesCompletedNCT05792787
- Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.CompletedNCT05778227Not applicable
- Sealer-Based Obturation With AH Plus Bioceramic Sealer vs. Warm Vertical Compaction With AH PlusCompletedNCT05763420Not applicable
- Mechanical Vs Chemomechanical Method For Calcium Hydroxide RemovalCompletedNCT05744661Not applicable
- Biodentine as an Apical Plug in Immature Permanent MolarsCompletedNCT05719987Not applicable
- Quantitative Assessment of the Efficacy of Sweeps Laser Activation SystemsCompletedNCT05718596Not applicable
- Quantitative Assessment of the Efficacy of Two Irrigation Activation SystemsCompletedNCT05690763Not applicable
- Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical PeriodontitisCompletedNCT05653947Not applicable
- Effects of Intracanal Cryotherapy on Endodontic Postoperative PainCompletedNCT05611736Not applicable
- Effect of NSRCT on HbA1c and Inflammatory Markers in Healthy and Type 2 Diabetes Patients With Apical PeriodontitisStatus unknownNCT05609747Not applicable
- Encapsulated Acellular System From Mesenchymal Stem Cells for Dental Pulp RegenerationStatus unknownNCT05599087Phase 1
- Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.Status unknownNCT05582421Early Phase 1
- Assessment of Different Disinfection Protocols on Regenerative Potential of Mature TeethCompletedNCT05557994Not applicable
- Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8CompletedNCT05525013Not applicable
- Adrenomedullin Upregulation in Apical PeriodontitisCompletedNCT05297747Not applicable
- Treatment of Young Permanent Teeth With Different Adjuvant ApproachesCompletedNCT05291195Not applicable
- Comparison Between RCT in Single and Two Visits, With and Without Intracanal Dressing, in Apical RepairStatus unknownNCT05256667Phase 2/3
- Evaluation of IL-17, TNF-alpha, RANKL Levels in Gingival Cervicular FluidStatus unknownNCT05232591
- The Effect of Different Irrigation and Disinfection Methods on Post-operative Pain (PP)CompletedNCT05195021Not applicable
- Effect of Primary Non-surgical Endodontic Therapy on Glycaemic Control in Type 2 Diabetic Patients With Asymptomatic Apical PeriodontitisCompletedNCT05170880Not applicable
- Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant.CompletedNCT05038059Not applicable
- Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .Status unknownNCT05021809Phase 4
- Intraoral Cryotherapy on Cytokine Levels and Postoperative Endodontic PainCompletedNCT05017064Not applicable
- Association of Apical Periodontitis With Hs-CRP and Hemogram IndicesStatus unknownNCT04980768Not applicable
- The Effect of Ca(OH)2 in Apical PeriodontitisCompletedNCT04978545Not applicable
- Effectiveness of GentleWave on the Healing of Apical Periodontitis: A Prospective Cohort StudyTerminatedNCT04966169Not applicable
- Serum Pro-Diabetes Inflammation Biomarkers in Patients With Apical Periodontitis.CompletedNCT04824209
- Healing of Apical periodontitis-the Effect of Diabetes Mellitus and Tobacco SmokingCompletedNCT04812171
- Cryotherapy on Inflammatory Profile and Postoperative Pain Levels in Endodontic InfectionsCompletedNCT04798144Not applicable
- Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.CompletedNCT04733326Phase 1
- Prospective Endodontics DatabaseStatus unknownNCT04716478
- Postoperative Pain After Using NiTi InstrumentsCompletedNCT04700995Not applicable
- Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical PeriodontitisActive, not recruitingNCT04672070Not applicable
- E. Faecalis Prevalence in Primary and Secondary Endodontic Infections: a Pre-post Microbial Analysis Following Chemo-mechanical PreparationCompletedNCT04637659
- Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical PeriodontitisCompletedNCT04606719Not applicable
- Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical PeriodontitisStatus unknownNCT04594317Not applicable
- "Effect of Apical Patency on Post-endodontic Pain"CompletedNCT04551209Not applicable
- Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical PeriodontitisCompletedNCT04545307Phase 2/3
- 2-year Treatment Outcomes of Teeth Estimated by Means of Periapical and Endodontic Status ScaleCompletedNCT04495270
- Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical PeriodontitisCompletedNCT04486196Not applicable
- Single And Multiple-visit Endodontic Retreatment Outcome.Status unknownNCT04390789Not applicable