An interventional study of Method in Apical Periodontitis, sponsored by Minia University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-09-28.
Sponsored by Minia University · Not applicable, Interventional, and Treatment
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis. Many researchers have begun to apply regenerative endodontic procedures to mature teeth in adult patients. Several clinical case reports have shown complete resolution of signs and symptoms of pulp necrosis in mature teeth, even those with large periapical lesions, as well as signs of pulp canal obliteration. The aim of this study is to assess the regenerative potential of mature permanent teethwith necrotic pulps after disinfecting the root canal using diode laser andcompare it with dynamic agitation of xp-endo finisher and conventionaltriple antibiotic paste
1,635 studies on the registry are indexed under Periodontitis; 327 are open to participants now.
This study's enrollment of 36 is below the median of 45 across 1,191 interventional studies indexed under Periodontitis.
Browse Periodontitis studies →Minia University is the lead sponsor of 356 studies on the registry; 115 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Patients with mature teeth. Patients with periapical periodontitis. Maxillary anterior teeth only will be involved. Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
Patients who will agree to the consent and will commit to follow up period.
Exclusion Criteria:
Blood clotting protocol for pulp regeneration of mature teeth
Other: Method
Compare different disinfection technique
Other: Method
treatment of mature teeth with apical periodontitis
Clinical success
pulp vitality testing using electric pulp tester which detect response of pulp to electric current
Time frame: 9 months
Radiographic success
healing of apical periodontitis by detecting change in apical radiolucency and absences of apical bone resorption
Time frame: 9 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Sep 2022. You cannot join it, but the record below documents what was studied.
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Minia University