Papilledema clinical trials

The registry lists 28 studies for Papilledema across more than 10 countries. 6 are recruiting or about to start. 5 of them are mainly about Papilledema (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-08.

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Status

Completed: 12
Status unknown: 7
Recruiting: 4
Terminated: 2
Not yet recruiting: 2
Withdrawn: 1

Phase

Phase 1: 6
Phase 2: 4
Phase 4: 3
Phase 3: 2
Early Phase 1: 1

Where

United States: 10
Switzerland: 3
France: 2
United Kingdom: 2
Egypt: 2
Germany: 1

Who runs them

National Eye Institute (NEI) (2) · University of Birmingham (2) · Capital Medical University (2) · Kovach Eye Institute (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Middle East North Africa Stroke and Interventional Neurotherapies Organization (1) · Cukurova University (1) · Rigmor Højland Jensen (1)

What is being tested here

Drugs under test in Papilledema studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Triamcinolone Acetonide	1	0	1
Triamcinolone	1	0	1
Prednisone acetate	1	0	1
Prednisone	1	0	1
Ranibizumab	0	0	2
Semaglutide	0	0	1
Azd-4017	0	0	1
Acetazolamide	0	1	1
Nepafenac	0	0	1
Dexamethasone	0	1	1

Drug classes tested here Corticosteroids 2 open

Coming up

0phase 3 studies under way

3studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3

Nov 2026Optic Nerve Sheath Diameter in Hypertensive Emergency · Leiden University Medical Center
Jul 2027B-Complex: A Nutraceutical SANS Countermeasure · National Aeronautics and Space Administration (NASA)
Aug 2027IIH Intervention: A Clinical Trial Comparing 2 Treatments (Shunts and Stents) Evaluation Of Clinical Effectiveness And Cost Effectiveness · University of Birmingham

Who these studies take

Of the 4 Papilledema studies recruiting now, 1 (25%) set no upper age limit and 2 (50%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (25%) take healthy volunteers.

Recruiting studies that take each age, of 4
Age	Women	Men
10	0 (0%)	0 (0%)
18	3 (75%)	3 (75%)
30	4 (100%)	4 (100%)
40	4 (100%)	4 (100%)
50	4 (100%)	4 (100%)
65	2 (50%)	2 (50%)
75	2 (50%)	2 (50%)
85	2 (50%)	2 (50%)

Across all 28 studies, recruiting or not: 29% stop at 75 or younger and 29% at 65; 29% take children; 11% are for women only and 0% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 28 of 28. search them.