Oligodendroglioma clinical trials
The registry lists 414 studies for Oligodendroglioma across more than 10 countries. 32 are recruiting or about to start. 23 of them are mainly about Oligodendroglioma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (57) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (22) · Duke University (21) · Pediatric Brain Tumor Consortium (14) · City of Hope Medical Center (12) · Wake Forest University Health Sciences (11) · Jonsson Comprehensive Cancer Center (10) · Children's Oncology Group (10)
What is being tested here
Drugs under test in Oligodendroglioma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Safusidenib | 4 | 2 | 4 |
| Temozolomide | 3 | 7 | 62 |
| G 207 | 1 | 0 | 2 |
| Oncolytic HSV-1 G207 | 1 | 0 | 2 |
| Cetuximab | 1 | 0 | 2 |
| Abexinostat | 1 | 0 | 1 |
| Mirdametinib | 1 | 0 | 1 |
| Olutasidenib | 1 | 0 | 1 |
| Eflornithine | 1 | 0 | 1 |
| Retifanlimab | 1 | 0 | 1 |
Drug classes tested here Alkylating agents 3 open · Immune checkpoint inhibitors 2 open · HDAC inhibitors 1 open · Tyrosine kinase inhibitors (TKIs) 35 · Antimitotic agents 17
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma · Phase 3 · Eastern Cooperative Oncology Group
- Nov 2026Pediatric Long-Term Follow-up and Rollover Study · Novartis Pharmaceuticals
- Dec 2026Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma · Columbia University
- Dec 2026Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas · M.D. Anderson Cancer Center
- Jan 2027A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 · Dana-Farber Cancer Institute
- Mar 2027Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms · Jazz Pharmaceuticals
- Jun 2027All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma · Stephen Bagley, MD, MSCE
- Jul 2027Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors · Memorial Sloan Kettering Cancer Center
- Jul 2027A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma · University of Nebraska
- Oct 2027Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile® · University of California, Irvine
Who these studies take
Of the 25 Oligodendroglioma studies recruiting now, 16 (64%) set no upper age limit and 7 (28%) stop at 75 or younger. 5 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (12%) | 3 (12%) |
| 18 | 23 (92%) | 23 (92%) |
| 30 | 21 (84%) | 21 (84%) |
| 40 | 20 (80%) | 20 (80%) |
| 50 | 20 (80%) | 20 (80%) |
| 65 | 19 (76%) | 19 (76%) |
| 75 | 18 (72%) | 18 (72%) |
| 85 | 17 (68%) | 17 (68%) |
Across all 414 studies, recruiting or not: 27% stop at 75 or younger and 22% at 65; 27% take children; <1% are for women only and <1% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Oligodendroglioma studies take
Of 43 phase 1 interventional studies under Oligodendroglioma, half reached primary completion within 44 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 44 mo35–70 · 43 studies | — | 44 mo35–92 · 36 studies |
| Phase 2 | 47 mo39–61 · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Newly registered1
- A Study of SRN-101 Gene Therapy in Adults With Recurrent High-Grade Glioma (ALERT-1)Oct 28, 2026NCT07902037
Studies
Recruiting first, then most recently updated. Showing 50 of 414. Browse all 414 → or search them.
- Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive DiseaseRecruitingNCT07703436Phase 21 country
- HMPL-306 in Participants With Postoperative Residual or Recurrent Grade 2 Glioma Harboring IDH1 or IDH2 MutationsNot yet recruitingNCT07912398Phase 3
- Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-BeingRecruitingNCT07628647Not applicable1 country
- A Study of SRN-101 Gene Therapy in Adults With Recurrent High-Grade Glioma (ALERT-1)Not yet recruitingNCT07902037Phase 1/2
- Implantable Microdevice In Primary Brain TumorsRecruitingNCT04135807Early Phase 11 country
- SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)RecruitingNCT05303519Phase 33 countries
- Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncologyRecruitingNCT046484621 country
- Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma.RecruitingNCT07439172Phase 21 country
- Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile®Not yet recruitingNCT07821112Phase 21 country
- Safusidenib for Patients With Newly Diagnosed IDH1-mutant CNS WHO Grade 3 Oligodendroglioma and Astrocytoma - a Single Arm Phase II StudyNot yet recruitingNCT07832123Phase 21 country
- A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent GliomaRecruitingNCT05698524Phase 11 country
- SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade GliomaRecruitingNCT04923126Phase 1/21 country
- FearLess in NeuroOncologyRecruitingNCT06989086Not applicable1 country
- Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 MutationRecruitingNCT07286292Phase 22 countries
- HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 11 country
- Study of Olutasidenib and Temozolomide in HGGRecruitingNCT06161974Phase 27 countries
- Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant GliomaNot yet recruitingNCT07712757Phase 3
- Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) GlioblastomasRecruitingNCT04623931Phase 21 country
- Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade GliomasRecruitingNCT07468136Phase 1/21 country
- PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmasRecruitingNCT05190172Not applicable1 country
- Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1RecruitingNCT07462507Phase 21 country
- All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant GliomaRecruitingNCT05345002Phase 21 country
- A Clinical Study to Improve Brain Function and Quality of Life of Patients With Newly Diagnosed Brain Tumors (Gliomas).RecruitingNCT05331521Phase 31 country
- A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than SurgeryRecruitingNCT04702581Phase 31 country
- Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of AgeRecruitingNCT05956821Phase 1/21 country
- HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)RecruitingNCT06930846Not applicable1 country
- Amino Acid PET-based Response Assessment in IDH-mutant Gliomas (APPEAR)RecruitingNCT071596072 countries
- Ga-68 Prostate Specific Membrane Antigen PET/CT in GliomasNot yet recruitingNCT06241391Not applicable1 country
- Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep LearningRecruitingNCT056247361 country
- Correlation Between Psychological Stress and Progression of Newly Oligodendroglioma Towards Secondary GliomaNot yet recruitingNCT05536986
- Sintilimab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for ctDNAlevel- Relapse and Clinical-relapse OligodendrogliomaRecruitingNCT05512351Phase 21 country
- Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade GliomaRecruitingNCT01649830Phase 31 country
- Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsActive, not recruitingNCT04541082Phase 11 country
- Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid TumorsTerminatedNCT00788125Phase 1/21 country
- Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade GliomasCompletedNCT02015819Phase 11 country
- ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult PatientsActive, not recruitingNCT06254326Phase 11 country
- Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2CompletedNCT01082926Phase 11 country
- Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade GliomaActive, not recruitingNCT00978458Phase 31 country
- INCB7839 in Treating Children With Recurrent/Progressive High-Grade GliomasCompletedNCT04295759Phase 11 country
- Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant GliomaCompletedNCT00730613Phase 1
- Abemaciclib in Patients With OligodendrogliomaCompletedNCT03969706Phase 21 country
- Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade GliomaActive, not recruitingNCT07031765Phase 11 country
- Pediatric Long-Term Follow-up and Rollover StudyActive, not recruitingNCT03975829Phase 419 countries
- Vorinostat and Temozolomide in Treating Patients With Malignant GliomasActive, not recruitingNCT00268385Phase 11 country
- Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade GliomaActive, not recruitingNCT061082061 country
- Social Determinants of Health in Glioblastoma PopulationCompletedNCT039006891 country
- Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain MetastasesTerminatedNCT03796273Early Phase 11 country
- Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III GliomaActive, not recruitingNCT03180502Phase 21 country
- Vorasidenib Expanded Access ProgramApproved for marketingNCT05592743
- Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain TumorsActive, not recruitingNCT03220646Phase 21 country