Non-ST Elevated Myocardial Infarction clinical trials
The registry lists 284 studies for Non-ST Elevated Myocardial Infarction across more than 10 countries. 52 are recruiting or about to start. 70 of them are mainly about Non-ST Elevated Myocardial Infarction (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Status
Who runs them
Karolinska Institutet (5) · Oslo University Hospital (5) · Collegium Medicum w Bydgoszczy (4) · Assiut University (4) · University of Leeds (4) · University College, London (4) · Cardio Med Medical Center (4) · University of Leipzig (3)
What is being tested here
Drugs under test in Non-ST Elevated Myocardial Infarction studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Bempedoic acid | 2 | 0 | 3 |
| Inclisiran | 2 | 1 | 2 |
| Evolocumab | 1 | 0 | 3 |
| Atorvastatin | 1 | 0 | 3 |
| Colchicine | 1 | 1 | 3 |
| Dapagliflozin | 1 | 1 | 2 |
| Ezetimibe | 1 | 0 | 2 |
| Alirocumab | 1 | 0 | 1 |
| Clopidogrel | 0 | 0 | 6 |
| Ticagrelor | 0 | 2 | 6 |
Drug classes tested here PCSK9 inhibitors 1 open · P2Y12 inhibitors 11
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes · Phase 3 · Novartis Pharmaceuticals
- Nov 2026TIRANA-ACS: A Prospective Registry Study for the Targeted Investigation of Residual Inflammation After Non-ST/ ST Elevation Acute Coronary Syndrome · University Hospital Centre Mother Teresa
- Nov 2026Smartphone AI Assistance for Prehospital ECG Interpretation · École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care
- Dec 2026Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock · Henry Ford Health System
- Dec 2026Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction · Region Stockholm
- Dec 2026OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial Infarction · Luzerner Kantonsspital
- Jan 2027Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI · Leipzig Heart Science gGmbH
- Feb 2027"Discovery2" Study of Using MCG at Emergency Departments · SB Technology, Inc.
- Mar 2027Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome · Clinical Center Niš
- Mar 2027MAchine Learning to Boost the Early Diagnosis of Acute Cardiovascular Conditions · University Hospital, Basel, Switzerland
Who these studies take
Of the 40 Non-ST Elevated Myocardial Infarction studies recruiting now, 34 (85%) set no upper age limit and 1 (3%) stop at 75 or younger. 4 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (8%) | 3 (8%) |
| 18 | 34 (85%) | 34 (85%) |
| 30 | 39 (98%) | 39 (98%) |
| 40 | 39 (98%) | 39 (98%) |
| 50 | 39 (98%) | 39 (98%) |
| 65 | 39 (98%) | 39 (98%) |
| 75 | 39 (98%) | 39 (98%) |
| 85 | 38 (95%) | 38 (95%) |
Across all 284 studies, recruiting or not: 10% stop at 75 or younger and 2% at 65; 6% take children; <1% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Non-ST Elevated Myocardial Infarction studies take
Of 23 phase 4 interventional studies under Non-ST Elevated Myocardial Infarction, half reached primary completion within 65 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 4 | 65 mo28–74 · 23 studies | — | — |
| Interventional, no phase | 27 mo18–70 · 55 studies | — | 29 mo14–70 · 48 studies |
| Observational | 32 mo19–49 · 76 studies | — | 40 mo15–86 · 54 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary SyndromeNov 5, 2026NCT07684742
- Breisgau PHENO-HEART MIOct 27, 2026NCT06166407
Stopped1
Newly registered1
- AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS)Oct 20, 2026NCT07882849
Studies
Recruiting first, then most recently updated. Showing 50 of 284. Browse all 284 → or search them.
- The Influence of Modifying Highly Calcified Coronary Lesions on Coronary MicrocirculationEnrolling by invitationNCT06507449Not applicable1 country
- Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary SyndromeRecruitingNCT07684742Phase 41 country
- Breisgau PHENO-HEART MIRecruitingNCT061664071 country
- AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS)Not yet recruitingNCT078828491 country
- Analysis of Life-threatening ARrhythMias After Acute Coronary SyndromeRecruitingNCT078240501 country
- Gangwon PCI Prospective RegistryRecruitingNCT020381271 country
- Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials StudyNot yet recruitingNCT078485291 country
- Germany on Target RegistryNot yet recruitingNCT07835282
- Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary SyndromeRecruitingNCT07824323Phase 41 country
- "Discovery2" Study of Using MCG at Emergency DepartmentsNot yet recruitingNCT078225811 country
- Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary SyndromesRecruitingNCT07102628Phase 314 countries
- Optimal Timing of Microaxial Flow Pump(Impella CP) in AMI-related Cardiogenic ShockNot yet recruitingNCT07817472Not applicable1 country
- Smartphone AI Assistance for Prehospital ECG InterpretationRecruitingNCT07810686Not applicable1 country
- Abbreviated Antithrombotic Therapy After PCI in Patients With AF and AMIRecruitingNCT07583784Not applicable1 country
- Left Atrial Strain for Predicting MACE in NSTEMINot yet recruitingNCT07797634
- Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial InfarctionRecruitingNCT065666251 country
- Diagnostic Performance of Artificial Intelligence Algorithms in Prediction of Acute Coronary Syndrome Based on White Blood Cell PropertiesRecruitingNCT063848461 country
- Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary SyndromeRecruitingNCT073666841 country
- Fast Discharge After Acute Myocardial Infarction Discharge MIRecruitingNCT06744322Not applicable2 countries
- Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically AloneRecruitingNCT07257198Phase 31 country
- Korea Acute Myocardial Infarction RegistryNot yet recruitingNCT074094411 country
- Safety and Effectiveness of the Crystalline Sirolimus-Eluting Device in Patients With Coronary Artery DiseaseRecruitingNCT074449571 country
- Early Discharge Pathway RegistryRecruitingNCT060405281 country
- Efficacy of Immediate Versus Staged Complete Revascularization in Patients With NSTE-ACS and Multivessel Disease (FUTURE II)Not yet recruitingNCT07343076Not applicable
- Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Artery DiseaseRecruitingNCT07368933Not applicable1 country
- European Unified Registries for Heart Care Evaluation and Randomised Trials ItalyRecruitingNCT072838091 country
- DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial InfarctionRecruitingNCT05764057Phase 31 country
- Breaking Fasts Ahead of Cardiac CathsRecruitingNCT06996639Not applicable1 country
- For Patients With Myocardial Infarction and Multiple Vessel: Testing if Ultrasound (UFR) Can Guide All Needed Treatment in One Procedure, Avoiding a Return Hospital Visit for a Second Operation.Not yet recruitingNCT072648811 country
- TIRANA-ACS: A Prospective Registry Study for the Targeted Investigation of Residual Inflammation After Non-ST/ ST Elevation Acute Coronary SyndromeRecruitingNCT070267081 country
- ECG-less Coronary Computed Tomography Angiography in the Management of Patients Presenting With High-troponin Chest PainRecruitingNCT07192965Not applicable1 country
- Short-Term Outcomes of Early Administration of Colchicine in Non-ST Segment Elevation Myocardial Infarction Patients Treated With Drug-Eluting Stents.RecruitingNCT07143136Early Phase 11 country
- MAchine Learning to Boost the Early Diagnosis of Acute Cardiovascular ConditionsRecruitingNCT069277911 country
- Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)RecruitingNCT06861582Not applicable1 country
- Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary SyndromeRecruitingNCT06101862Not applicable1 country
- Evaluation of Remnant Cholesterol Levels and Monocyte-to-HDL-cholesterol Ratio As Predictors of Coronary Artery Disease Severity in Patients with Acute Coronary SyndromeNot yet recruitingNCT06757777
- Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMIRecruitingNCT05786131Not applicable2 countries
- Assessment of ECMO in Acute Myocardial Infarction Cardiogenic ShockRecruitingNCT04184635Not applicable1 country
- IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute MIRecruitingNCT05812963Not applicable1 country
- Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)RecruitingNCT05182970Phase 31 country
- Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimicsRecruitingNCT06323811Not applicable1 country
- Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)Not yet recruitingNCT05587621Not applicable1 country
- Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac ArrestRecruitingNCT05961488Not applicable1 country
- Low Risk Non ST Elevation Myocardial Infarction With or Without Intensive Care Unit AdmissionRecruitingNCT05153889Not applicable1 country
- What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI?RecruitingNCT04436978Phase 42 countries
- Distal Radial Access for Coronary ProceduresRecruitingNCT061654061 country
- Assessment of the Effects of Long-term Lipid-lowering Therapy in Patients With Primary STEMI or NSTEMIRecruitingNCT04347434Phase 41 country
- OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial InfarctionRecruitingNCT049886721 country
- Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe LesionsRecruitingNCT050566621 country
- Beta Blocker De-prescription Following Coronary Artery Bypass Graft Surgery (BEEFBURGER Trial).RecruitingNCT04788186Phase 41 country