Neurodegenerative Diseases: all 436 studies

Page 3 of 5. Open to participants first (143), then studies with results posted, then the rest; newest registration first within each.

• Establish the First International Database on Semi-quantitative Values Obtained in Scintigraphy With Datscan® in Cadmium-Zinc-Telluride CameraCompletedNCT06828705
• Understanding How Gut and Brain Barriers Are Linked to Inflammation in ObesityCompletedNCT06787001
• Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCIActive, not recruitingNCT06755164Not applicable
• A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease PatientsCompletedNCT06745583Phase 2
• Parkinson and the Males Body CompositionCompletedNCT06723210
• A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)Active, not recruitingNCT06706622Phase 3
• A Phase 3 Study of NTLA-2001 in ATTRv-PNActive, not recruitingNCT06672237Phase 3
• ENHANCING PHYSICAL and COGNITIVE EFFICIENCY in INDIVIDUALS AT RISK of DEMENTIA USING WHOLE-BODY ELECTROMYOSTIMULATIONCompletedNCT06669598Not applicable
• Clinical Study of HER-096 in Healthy Volunteer Subjects and Patients With Parkinson's DiseaseCompletedNCT06659562Phase 1
• Mindfulness-based Lifestyle Modification Programme for Caregivers of People With Neurodegenerative Disorders: A Pilot Randomised Controlled TrialCompletedNCT06583018Not applicable
• NAD+ Oral Supplement Pilot Intervention in Adult FemalesCompletedNCT06579209Not applicable
• Enhancement of Quality of Work And LifeActive, not recruitingNCT06573866Not applicable
• Brain-computer Interface Commercial ReadinessCompletedNCT06521736Not applicable
• A Prospective, Monocentric Clinical Study for the Validation of in Vitro Diagnostic Tests Developed by FiralisCompletedNCT06432192
• Long-term Extension of Phase 3 Study of ALZ- 801 in APOE4/4 Early AD SubjectsTerminatedNCT06304883Phase 3
• The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive ImpairmentCompletedNCT06281314Not applicable
• Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's DiseaseActive, not recruitingNCT06268886Phase 2
• An Extension Study to Evaluate the Long-Term Safety and Efficacy of Votoplam in Participants With Huntington's Disease (HD)Active, not recruitingNCT06254482Phase 2
• Increasing Diagnosis Rates While Reducing Examination Time: Can MR Fingerprinting Deliver on Its Promise?CompletedNCT06251830
• A Phase Ia/Ib, First-in-human (FIH) Study for Safety, Tolerability, Pharmacokinetics (PK), and Clinical Activity Evaluation of ADEL-Y01TerminatedNCT06247345Phase 1
• Clinical Application of the Prototype J-PET DeviceCompletedNCT06211803
• Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register StudyActive, not recruitingNCT06209515
• Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1CompletedNCT06204809Phase 1
• A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)Active, not recruitingNCT06185764Phase 1/2
• Home-Based Exercise in Primary Progressive Aphasia (HEPPA)CompletedNCT06181500Not applicable
• Study of Cerebral Glucose Metabolism in Neurodegenerative Diseases and Head TraumaCompletedNCT06180213
• Understanding Ayurveda Disease Conditions and Treatment ResponsesCompletedNCT06167226
• Randomized Clinical Trial in Parkinson's Disease Patients Using Pluripotent Adipose Stem Cells (PASCs)CompletedNCT06141317Phase 1/2
• AMX0035 and Progressive Supranuclear PalsyCompletedNCT06122662Phase 2/3
• Continuation Study for LatozinemabTerminatedNCT06111014Phase 3
• A Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2)No longer availableNCT06069934
• A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's DisorderActive, not recruitingNCT06021522Phase 3
• Study of the Relation Between the Fat Infiltration of the Multifidus Muscle and the Lumbar Foraminal Stenosis, by 2D and 3D SegmentationCompletedNCT06018155
• Safety and Gut Microbiota Analysis of an Oral Microbiotherapy in Patients With Amyotrophic Lateral SclerosisCompletedNCT05889572Phase 1
• A Biomarker Study of ATH434 in Participants With MSACompletedNCT05864365Phase 2
• Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PDCompletedNCT05819359Phase 2
• A First Time in Human Study of SNP318 as a Treatment for Neurodegenerative Diseases Including Alzheimer's DiseaseCompletedNCT05792163Phase 1
• The Role of Humanoid Robot in Neuropsychological Assessment and Cognitive Training.CompletedNCT05788133Not applicable
• Correlation Between Melatonin Levels in Different Biological FluidsStatus unknownNCT05784090
• Big Data and Genomic Imaging for the Development of Biomarkers and Nanovector Drugs Innovative for Diagnosis and Therapy of Inflammatory Processes in DementiaCompletedNCT05761535
• Role of Saffron and Chamomile in the Management of Parkinson's DiseaseStatus unknownNCT05696665Not applicable
• Trial to Evaluate the Efficacy and Safety of KM-819 Treatment to Slow the Progression of Multiple System Atrophy (MSA)TerminatedNCT05695378Phase 2
• Multiple-dose Trial to Determine the Clinical Bioequivalence Between Tavapadon Tablets in Participants With Parkinson's DiseaseCompletedNCT05610189Phase 1
• Experimentation of a Personalized Physical Self-education Program at Home: Feasibility Study (PROSOL TELEKINECT)WithdrawnNCT05597592Not applicable
• Cortical Disarray Measurement in Mild Cognitive Impairment and Alzheimer's DiseaseActive, not recruitingNCT05579236
• A Study to Evaluate AB-1001 Striatal Administration in Adults With Early Manifest Huntington's DiseaseActive, not recruitingNCT05541627Phase 1/2
• Investigating ProCare4Life Impact on Quality of Life of Elderly Subjects With Neurodegenerative DiseasesCompletedNCT05538455Not applicable
• A Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)CompletedNCT05532358Phase 1
• A Bridging Study on Efficacy and Safety of [18F]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese PopulationCompletedNCT05527288Not applicable
• An Open-Label Extension of XPro1595 in Patients With Alzheimer's DiseaseTerminatedNCT05522387Phase 2
• A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)Active, not recruitingNCT05508789Phase 3
• Personalized Parkinson Project PSP CohortCompletedNCT05501431
• Tau And Connectomics In TES StudyActive, not recruitingNCT05490576Phase 1
• HIFT in People With Parkinson's DiseaseCompletedNCT05482776Not applicable
• Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) PatientsCompletedNCT05479981Phase 2
• Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease ParticipantsActive, not recruitingNCT05469360Phase 1
• Intensive Multidisciplinary Rehabilitation and Biomarkers in Parkinson's DiseaseStatus unknownNCT05452655Not applicable
• Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar AtaxiaCompletedNCT05436249Not applicable
• Joint Consultation Between a Neurologist and a Clinical PsychologistStatus unknownNCT05394974
• Are Postoperative Patient PROMS Influenced by Recall of Preoperative Scores?CompletedNCT05360199Not applicable
• Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of InflammationWithdrawnNCT05321498Phase 2
• Clearance Mechanisms in Atypical Neurodegenerative DiseasesStatus unknownNCT05317871
• A Study of the Natural Course of SURF1 DeficiencyWithdrawnNCT05277363
• Long-term Follow-up in Severe Traumatic Brain InjuryStatus unknownNCT05235802
• Multiple N-of-1 Trials of (Intermittent) Hypoxia Therapy in Parkinson's DiseaseCompletedNCT05214287Phase 1/2
• Promoting Physical Activity Engagement for People With Early-stage Cerebellar AtaxiaActive, not recruitingNCT05157802Phase 1
• A FIH Study to Assess the Safety and Tolerability of NS Intravenous NS101 InfusionCompletedNCT05143463Phase 1
• Laser Shoes for Freezing in People With Parkinson's DiseaseStatus unknownNCT05131906Not applicable
• Pilot Study to Evaluate the Self-Management of Gait, Speech, and Dexterity Symptoms in Parkinson's Disease Using a Smartphone ApplicationStatus unknownNCT05120609Not applicable
• Study of ATH434 in Participants with Multiple System AtrophyCompletedNCT05109091Phase 2
• Effect of Meditation and Controls and Subjects With Parkinson's Disease on Brain Activity Measured by fMRI With FDOPAWithdrawnNCT05103618Phase 2
• Evaluation of the Peripheral Nerve Ultrasound as a Diagnostic Tool in CANVAS NeuropathiesCompletedNCT05095870
• Pharmacokinetic and Pharmacodynamic Study of AMX0035 in Patients With ALSActive, not recruitingNCT04987671Phase 1/2
• The Personalized Parkinson Project De Novo CohortActive, not recruitingNCT04985539
• Quality of Life of Caregivers and Patients Suffering From Multiple System AtrophyCompletedNCT04965922Not applicable
• Dopaminergic Therapy for Frontotemporal Dementia PatientsCompletedNCT04937452Phase 2
• Tau PET Imaging With 18F-T807(AV1451) in Neurodegenerative DisordersStatus unknownNCT04926259Early Phase 1
• Home-based Cognitive Treatment and Cognitive ImpairmentStatus unknownNCT04889560Not applicable
• Inflammation and Neurocognitive Damage Markers in Elderly People With Obstructive Sleep ApneaStatus unknownNCT04882020
• Neuropsychological Indicators of SCD ProgressionCompletedNCT04880252
• Role and Mechanism of Probiotics in Improving Motor Symptoms in Mild to Moderate Parkinson's DiseaseStatus unknownNCT04871464Phase 4
• Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's DiseaseActive, not recruitingNCT04838301Phase 2
• Cerebrovascular Reactivity and Oxygen Metabolism as Markers of Neurodegeneration After Traumatic Brain InjuryStatus unknownNCT04820881
• Risk of Developing Dementia and Associated Factors in Patients With Normal Brain FDG PETCompletedNCT04804722
• Validation of the NeuroTec LoftCompletedNCT04793555Not applicable
• Open-label Trial in Parkinson's Disease (PD)CompletedNCT04760769Phase 3
• A ToM Training for People With Multiple Sclerosis: an Efficacy Study.Status unknownNCT04711941Not applicable
• Synuclein-One StudyCompletedNCT04700722
• A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of anle138b in Parkinson's DiseaseCompletedNCT04685265Phase 1
• Safety of SNK01 in Subjects With Alzheimer's Disease (ASK-AD)TerminatedNCT04678453Phase 1
• LRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's DiseaseCompletedNCT04668898
• Extreme Lateral Interbody FusionFUSION (XLIF) Versus Posterior Lumbar Interbody Fusion (PLIF)SuspendedNCT04589572Not applicable
• A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of ONO-2808-01 in Healthy ParticipantsCompletedNCT04578028Phase 1
• Exploratory Evaluation of [11C]MPC6827CompletedNCT04575727Early Phase 1
• Early Longitudinal Imaging in Parkinson's Progression Markers Initiative Using [¹⁸F] AV-133 and DaTscan™Active, not recruitingNCT04507139
• Tocotrienols in Parkinson's Disease (PD)Active, not recruitingNCT04491383Phase 2
• Near-Infrared Laser Stimulation for Various Neurological ConditionsStatus unknownNCT04489082Not applicable
• FDOPA PET and Nutritional Support in Parkinson's DiseaseActive, not recruitingNCT04459052Phase 2
• Development and Test of a Headset for BCI Until Obtaining an Efficient and Comfortable System That Can be Used in Daily Practice by ALS PeopleActive, not recruitingNCT04380649Not applicable
• Metabolomics Profiling Research of Human Cerebrospinal Fluid in Aging ProcessCompletedNCT04315038

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