Nerve Degeneration: all 147 studies

Page 1 of 2. Open to participants first (55), then studies with results posted, then the rest; newest registration first within each.

• LM11A-31 Safety and Tolerability in Aging People Living With HIV and Neurocognitive ImpairmentNot yet recruitingNCT07934186Phase 1/2
• MK-0947 PN-002: An Open-label Study to Evaluate Brain α-synuclein Deposition Using Positron Emission Tomography (PET) and [¹⁸F]MK-0947 in Participants With Parkinson's Disease (PD)RecruitingNCT07880379Phase 1
• Brain Iron in Beta-Propeller Protein Associated Neurodegeneration (BPAN)Not yet recruitingNCT07868120Not applicable
• Evaluation of Blood-Based Biomarkers and Remote Cognitive Assessment for Dementia Triage (SANDBOX)RecruitingNCT07842029
• Magnetic Resonance Imaging of Cerebral Connectivity and Volume in Neurodegeneration and GlaucomaRecruitingNCT07802769Not applicable
• Biofluid Research on Age-Related or Inherited NeurodegenerationRecruitingNCT07798700
• Developing a Comprehensive Biomarker Panel for Monitoring Progression and Early Detection in ALS PatientsNot yet recruitingNCT07737977
• Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation WardsRecruitingNCT07731334Not applicable
• Optical Coherence Tomography in Neurological Practice: Utility and Applicability Across Neurological Diseases (OCt.IN.N)RecruitingNCT07720765
• Retinal OCT Changes and Biomarkers in Drug-Resistant EpilepsyEnrolling by invitationNCT07716930
• Passive Versus Active Music Therapy Parkinson's DiseaseNot yet recruitingNCT07661524Not applicable
• Vestibular Stimulation in Sleep for Neurorehabilitation PatientsNot yet recruitingNCT07658027Not applicable
• Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot PhaseRecruitingNCT07640542Early Phase 1
• Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Depressive Symptoms in Patients With Parkinson's DiseaseEnrolling by invitationNCT07569133Not applicable
• Protecting the Brain From Post-Stroke Cognitive Impairment and Dementia With Multimodal Exercise TrainingRecruitingNCT07445841Not applicable
• Auditory Sleep Stimulation or Sham in People With Parkinson Disease Mild Cognitive Impairment During Cognitive TrainingRecruitingNCT07441915Not applicable
• Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)RecruitingNCT07435467
• German Dementia RegistryRecruitingNCT07433010
• ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older AdultsRecruitingNCT07392723Phase 2
• Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.RecruitingNCT07361887Not applicable
• Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior DisorderRecruitingNCT07355842Not applicable
• Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve BiopsyRecruitingNCT07268833
• Kisspeptin to Quantify GnRH Neuronal Function in Health and DiseaseRecruitingNCT07224490Phase 1
• AV-1980R (Tau Vaccine) in Preclinical Alzheimer's Disease (TAURUS-1980)RecruitingNCT07158905Phase 1
• A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's DiseaseRecruitingNCT07157735Phase 2
• Effect of Vitamin D3 on Brain Waves in Male Parkinson's Patients With Low Vitamin D: A qEEG StudyRecruitingNCT07096336Not applicable
• Clinical Impact Through AI-assisted MS Care - A Prospective Multi-center StudyEnrolling by invitationNCT07032246Not applicable
• Imaging Studies in Corticobasal SyndromeRecruitingNCT07000851
• Alzheimer's Tau Platform: Master ProtocolRecruitingNCT06957418Phase 2
• Neuromodulation and fMRI in Neurodegenerative Diseases StudyNot yet recruitingNCT06873750Not applicable
• Tau PET/CT in Various Tau-Related Disease PatientsRecruitingNCT06690983
• Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and GaitRecruitingNCT06688578Not applicable
• Neurofilament Light Chain And Voice Acoustic Analyses In Dementia DiagnosisRecruitingNCT06339190
• Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone DiseaseRecruitingNCT06320444
• BrainAgeMS - a Comparative Study of Brain Aging in Healthy and Patients With Multiple SclerosisRecruitingNCT06221631
• Detection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of ImmunityRecruitingNCT06169150
• Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea PatientsRecruitingNCT06167369
• Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's DiseaseRecruitingNCT06088355Not applicable
• Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate ToxicityRecruitingNCT06021262
• Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical ADRecruitingNCT05881239
• Superior Cervical Ganglion in Parkinson's DiseaseRecruitingNCT05741151Not applicable
• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) StudyRecruitingNCT05677880
• Serotonin Release in Premotor and Motor PDRecruitingNCT05516732
• Longitudinal Investigation of I2BS in PDRecruitingNCT05516719
• China Longitudinal Aging and Cognitive Impairment StudyRecruitingNCT05468905
• Progression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior DisorderRecruitingNCT05353959
• PREdictive Risk Factors of Conversion Into Idiopathic RBD. Italian StudyRecruitingNCT05262543
• Synaptic Loss in Multiple System AtrophyRecruitingNCT05121012
• Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial BranchRecruitingNCT05091112
• Gut Microbiota in Major Depressive Disorders With and Without Rapid Eye Movement Behavior DisorderRecruitingNCT05008120
• Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)RecruitingNCT04124029
• Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPARecruitingNCT03887481Not applicable
• Biomarkers of Synaptic Damage in Multiple SclerosisRecruitingNCT03217396
• Neurologic Stem Cell Treatment StudyRecruitingNCT02795052Not applicable
• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
• Early Parkinson's Disease Monotherapy With CVN424CompletedNCT06006247Phase 2Results posted
• A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory EpilepsyTerminatedNCT04378075Phase 2/3Results posted
• 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's DiseaseCompletedNCT03815916Phase 2Results posted
• Neuroplasticity in Parkinson´s Disease After TrainingCompletedNCT03213873Not applicableResults posted
• tDCS Intervention in Primary Progressive AphasiaCompletedNCT02606422Not applicableResults posted
• Effect of Fingolimod on NeurodegenerationTerminatedNCT02575365Phase 4Results posted
• Augmenting Cerebral Blood Flow to Treat Established Multiple SclerosisTerminatedNCT02466074Phase 2Results posted
• Alpha-lipoic Acid/L-acetyl Carnitine for Progressive Supranuclear PalsyCompletedNCT01537549Phase 1/2Results posted
• Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl CysteineCompletedNCT00975689Phase 1/2Results posted
• Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT00818389Phase 2/3Results posted
• Copper Histidine Therapy for Menkes DiseasesCompletedNCT00001262Phase 1/2Results posted
• Predicting Parkinson's Disease Before It Strikes: A Brain Imaging Study in At-Risk IndividualActive, not recruitingNCT07729748
• SGLT2 Inhibitors and Cognitive Function in Adults With Type 2 Diabetes (SaveMinD)Active, not recruitingNCT07694596Not applicable
• Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's DiseaseTerminatedNCT07348250Early Phase 1
• Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's DiseaseCompletedNCT07294586
• Home Transcranial Direct Current Stimulation (tDCS) to Enhance Functional RecoveryActive, not recruitingNCT07091396Not applicable
• Impact of Ketoflex 12/3 Diet on Early-to-Mid Stage Alzheimer's ProgressionCompletedNCT06898424Not applicable
• Neuroinflammation in FTLDActive, not recruitingNCT06870838
• Periodontitis Provokes Retinal Neurodegenerative Effects of Metabolic Syndrome: A Cross-Sectional StudyCompletedNCT06638580
• Quantifying the Trainability of Peripheral Nerve Function in Young and Older Adults.CompletedNCT06614556Not applicable
• Phase 2 Estimation Study of Fixed Dose Drugs Combination Type of PolypillCompletedNCT06597058Phase 2
• Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential TremorActive, not recruitingNCT06349538
• Glycemic Control and Retinal Microvascular ChangesActive, not recruitingNCT06150495
• Heading in Football: Impact on Neural Blood BiomarkersCompletedNCT06147596
• The Effects of the MIND Diet on Oxidative Stress, Inflammation and Neurodegenerative Risk BiomarkersCompletedNCT05982860Not applicable
• Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And NeurodegenerationActive, not recruitingNCT05893225Phase 2
• Normal Pressure Hydrocephalus Biomarkers InvestigationStatus unknownNCT05562596
• Clinicopathological MRI and CSF Correlates in Huntington's Disease.Status unknownNCT05534139
• Microbiome, Anxiety and Cognitive Orientation StudyStatus unknownNCT05388630
• Evaluation of the Role of Neurodegeneration in SchizophreniaCompletedNCT05257720
• Evaluation of Relapse Presence in Multiple SclerosisCompletedNCT05218317
• Integration of Auditory, and Deep Brain Stimulation to Enhance Deep Sleep in Parkinson's DiseaseCompletedNCT05184270Not applicable
• Terazosin and Parkinson's Disease Extension StudyActive, not recruitingNCT05109364Phase 2
• EEG and TMS-based Biomarkers of ALS, MS and FTDStatus unknownNCT04918251
• Comparison of Power Wheelchair Driving Performance Under Immersive and Non-immersive Conditions With Drivers With Neurological DisordersCompletedNCT04894981Not applicable
• Retinal Neurodegeneration In Type 2 Diabetes Mellitus Detected by Optical Coherence TomographyStatus unknownNCT04808804
• Auditory Slow Wave Enhancement in Parkinson Disease and Mild Cognitive ImpairmentStatus unknownNCT04736017Not applicable
• Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine AddictionStatus unknownNCT04687566Phase 2/3
• Retinal Neurodegenerative and Vascular Changes in Diabetic PatientsCompletedNCT04637217
• Neurofilament Light- Chain in Ataxia TelangiectasiaStatus unknownNCT04605523
• Mental Practice (MP) Combined With Transcranial Direct Current Stimulation (tDCS) on Motor Learning in the ElderlyStatus unknownNCT04605367Not applicable
• Natural History Study of SLC25A46 Mutation-related MitochondriopathyCompletedNCT04594590
• Obesity and Pediatric Multiple SclerosisActive, not recruitingNCT04593082
• Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson DiseaseStatus unknownNCT04589182Not applicable
• Natural History Study of FDXR Mutation-related MitochondriopathyCompletedNCT04580979

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