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Neoplasms, Second Primary clinical trials

The registry lists 96 studies for Neoplasms, Second Primary across more than 10 countries. 35 are recruiting or about to start. 46 of them are mainly about Neoplasms, Second Primary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

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Drug B with hormone therapy in advanced breast cancer

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· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

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Status

Completed
42
Recruiting
29
Status unknown
11
Not yet recruiting
5
Withdrawn
3
Terminated
3

Phase

Phase 2
10
Phase 4
5
Phase 3
5
Phase 1
2

Where

United States
18
China
16
Canada
10
France
9
Italy
5
Spain
5

Who runs them

The Hospital for Sick Children (4) · Seoul National University Hospital (3) · Peking University Third Hospital (2) · Selcuk University (2) · Ludwig-Maximilians - University of Munich (2) · Celgene (2) · Second Xiangya Hospital of Central South University (2) · Soonchunhyang University Hospital (2)

What is being tested here

Drugs under test in Neoplasms, Second Primary studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Sacubitril valsartan101
Dostarlimab101
Letrozole111
Bicalutamide111
Everolimus111
Itraconazole111
Capecitabine111
Temozolomide002
Varenicline001
Bupropion001

Coming up

2phase 3 studies under way
5studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 5

Who these studies take

Of the 29 Neoplasms, Second Primary studies recruiting now, 18 (62%) set no upper age limit and 8 (28%) stop at 75 or younger. 4 (14%) take children under 18. 4 (14%) are for women only and 1 (3%) for men only; 2 (7%) take healthy volunteers.

Recruiting studies that take each age, of 29
AgeWomenMen
103 (10%)3 (10%)
1825 (86%)23 (79%)
3026 (90%)24 (83%)
4025 (86%)23 (79%)
5025 (86%)23 (79%)
6526 (90%)22 (76%)
7525 (86%)21 (72%)
8521 (72%)18 (62%)

Across all 96 studies, recruiting or not: 25% stop at 75 or younger and 13% at 65; 18% take children; 9% are for women only and 2% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Neoplasms, Second Primary studies take

Of 26 interventional studies with no phase under Neoplasms, Second Primary, half reached primary completion within 24 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase24 mo10–61 · 26 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 96. Browse all 96 → or search them.