Multiple System Atrophy: all 208 studies

Page 1 of 3. Open to participants first (73), then studies with results posted, then the rest; newest registration first within each.

• Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual TrialRecruitingNCT07863180Phase 1/2
• VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and ParkinsonismNot yet recruitingNCT07827963
• A Trial of ONO-2808 in Participants With the Parkinsonian Subtype of Multiple System Atrophy (MSA-P)Not yet recruitingNCT07825402Phase 3
• Multi-Center Study of Natural History in Atypical Parkinsonian Syndromes (MAPS-NH)RecruitingNCT07805967
• A Prospective Exploratory Study of the Safety and Preliminary Efficacy of the α-Syn H21 Monoclonal Antibody in Patients With Multiple System AtrophyNot yet recruitingNCT07774585Phase 1
• Open-Label Access to ATH434 for Patients Who Completed Study ATH434-201 in FranceEnrolling by invitationNCT07729852Phase 2
• Prospective Multicenter Registry Study of Multiple System Atrophy in ChinaRecruitingNCT07644013
• Evaluation of [¹⁸F]MODAG-009 PET Imaging in SynucleinopathiesRecruitingNCT07640555Early Phase 1
• Evaluation of the Pharmacokinetics, Biodistribution and Radiation Dosimetry of [18F]MODAG-009 Positron Emission Tomography (PET) Radiotracers in Adult Healthy VolunteersRecruitingNCT07617688Early Phase 1
• Early Molecular Biomarkers for Differentiating Parkinsonian SyndromesNot yet recruitingNCT07604883
• A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSARecruitingNCT07604116Phase 1
• Individualized Transcranial Magnetic Stimulation in Parkinsonian DisordersRecruitingNCT07570212Not applicable
• Post-Trial Access to ATH434 for Patients With Multiple System AtrophyAvailableNCT07531433
• Efficacy and Safety of Butylphthalide in the Treatment of Multiple System AtrophyRecruitingNCT07518810Phase 2/3
• The Study of Safety and Preliminary Efficacy of ALT001 in Patients With MultIple System Atrophy-Cerebellar TypeRecruitingNCT07514923Early Phase 1
• Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic DisordersRecruitingNCT07509125Not applicable
• Expansion Study of ALT001 in Patients With Multiple System AtrophyRecruitingNCT07476352Early Phase 1
• Autologous Stem Cell Therapy in Patients With Multiple System AtrophyNot yet recruitingNCT07465198Phase 2
• MSA-01 in Multiple System AtrophyRecruitingNCT07446894Phase 3
• Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital BiomarkersRecruitingNCT07392411
• Shanghai Clinical Cohort - Parkinson's Disease (Reserve)RecruitingNCT07353463
• Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical ActivityRecruitingNCT07324330Not applicable
• "An Intermediate Size Patient Population Expanded Access Protocol to Evaluate the Safety and Efficacy of Allogeneic HB-adMSCs (Hope Biosciences - Adipose Derived Mesenchymal Stem Cells) for the Treatment of Multiple System Atrophy."AvailableNCT07238062
• An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System AtrophyRecruitingNCT07197866Phase 2
• AB-1005 Long-Term Follow-up StudyEnrolling by invitationNCT07081841
• Efficacy and Safety of Bilateral Cervical Lymphatic-Venous Anastomosis in the Treatment of Multiple System AtrophyNot yet recruitingNCT07036939Not applicable
• AI-Enhanced Optimization of Acute Levodopa Challenge TestRecruitingNCT06949865
• [18F]ACI-15916 PET in α-synucleinopathiesRecruitingNCT06891703Early Phase 1
• TSPO PET in the Evaluation of Neuroinflammation in Patients with Multiple System AtrophyRecruitingNCT06890390
• Targeted Α-synuclein PET Imaging in the Diagnosis of Multiple System AtrophyRecruitingNCT06890377
• A Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)RecruitingNCT06868628Phase 2
• Transcutaneous Spinal Cord Stimulation Home StudyRecruitingNCT06838637Not applicable
• The Study of Safety and Preliminary Efficacy of Aleeto in Patients With MultIple System AtrophyRecruitingNCT06765733Early Phase 1
• Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous SystemEnrolling by invitationNCT06745011
• Autologous suraL nervE Grafting to the Substantia nigrA in Patients With SynuclienopathiesRecruitingNCT06683365Phase 1
• The CurePSP Genetics ProgramRecruitingNCT06647641
• Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian SyndromesRecruitingNCT06645626
• hUC-MSC-sEV-001 Nasal Drops for Neurodegenerative DiseasesNot yet recruitingNCT06607900Phase 1
• Parkinson Atypical Rating of Oculometric Patterns Evaluated RoutinelyEnrolling by invitationNCT06597071Not applicable
• Neurodegenerative Diseases Progression Markers (MARKERS-NDD)RecruitingNCT06596746
• NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian SyndromeRecruitingNCT06490926
• NYSCF Scientific Discovery BiobankRecruitingNCT06203106
• The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related DisordersRecruitingNCT06174948Not applicable
• The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical ParkinsonismRecruitingNCT06162013Phase 2
• [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD Vs. MSA and DLB Vs. ADRecruitingNCT06120049Phase 2/3
• PET Imaging Evaluation of [11C]SY08RecruitingNCT06098612Early Phase 1
• Medical Decision Making in Multiple System AtrophyRecruitingNCT06072105Not applicable
• North American Prodromal Synucleinopathy Consortium Stage 2Enrolling by invitationNCT05826457
• Pain and Autonomic Symptoms in Parkinson's Disease and Atypical ParkinsonismsRecruitingNCT05748028
• CPAP for the Treatment of Supine HypertensionRecruitingNCT05489575Not applicable
• Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement DisordersRecruitingNCT05486806
• The Effect of Gluten-free Diet on ParkinsonismRecruitingNCT05238545Not applicable
• Evaluation of the Efficacy of a Two-week EMST on Dysphagia in Parkinsonian PatientsRecruitingNCT05139342Not applicable
• Synaptic Loss in Multiple System AtrophyRecruitingNCT05121012
• Abdominal Binders to Treat Orthostatic Hypotension in Parkinsonian SyndromesRecruitingNCT04920552Not applicable
• Cerebro Spinal Fluid Collection (CSF)RecruitingNCT04844060
• Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension SymptomsRecruitingNCT04782830Not applicable
• Comprehensive Swallowing Rehabilitation in Patients With MSARecruitingNCT04782284Not applicable
• Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative DiseasesRecruitingNCT04706234
• Neurodegenerative Diseases RegistryRecruitingNCT04472130
• Insulin Resistance in Multiple System AtrophyRecruitingNCT04250493Not applicable
• [18F]F-DOPA Imaging in Patients With Autonomic FailureRecruitingNCT04246437Phase 1
• Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)RecruitingNCT04165486Phase 1
• Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using NeuroimagingRecruitingNCT03872102
• Multiple System Atrophy Multidisciplinary ClinicRecruitingNCT03811808
• North American Prodromal Synucleinopathy ConsortiumEnrolling by invitationNCT03623672
• Treatment of Supine Hypertension in Autonomic Failure (CPAP)RecruitingNCT03312556Not applicable
• The Swedish BioFINDER 2 StudyRecruitingNCT03174938Not applicable
• Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine HypertensionRecruitingNCT03042988Not applicable
• Modifiable Variables in Parkinsonism (MVP)RecruitingNCT02194816
• Biomarkers in Parkinsonian SyndromesRecruitingNCT02114242
• Natural History Study of SynucleinopathiesRecruitingNCT01799915
• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
• A Phase 2 Study of ONO-2808 in Patients With Multiple System AtrophyActive, not recruitingNCT05923866Phase 2Results posted
• A Study of TAK-341 in Treatment of Multiple System AtrophyCompletedNCT05526391Phase 2Results posted
• A Study of Lu AF82422 in Participants With Multiple System AtrophyActive, not recruitingNCT05104476Phase 2Results posted
• Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure PatientsCompletedNCT04620382Early Phase 1Results posted
• Exenatide Once-weekly as a Treatment for Multiple System AtrophyCompletedNCT04431713Phase 2Results posted
• A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese PatientsCompletedNCT04193527Phase 3Results posted
• Study of BHV-3241 in Participants With Multiple System AtrophyCompletedNCT03952806Phase 3Results posted
• Safinamide for Multiple System Atrophy (MSA)CompletedNCT03753763Phase 2Results posted
• A Futility Trial of Sirolimus in Multiple System AtrophyTerminatedNCT03589976Phase 2Results posted
• In-Home Care for Patients With PSP and Related DisordersCompletedNCT03552484Not applicableResults posted
• Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative AtaxiaCompletedNCT03120013Not applicableResults posted
• TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)CompletedNCT02705755Phase 2Results posted
• Local Heat Stress in Autonomic Failure Patients With Supine HypertensionCompletedNCT02417415Not applicableResults posted
• AZD3241 PET MSA Trial, Phase 2, Randomized,12 Week Safety and Tolerability Trial With PET in MSA PatientsCompletedNCT02388295Phase 2Results posted
• Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin.CompletedNCT02064166Phase 2Results posted
• Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-ApproachCompletedNCT02008721Phase 3Results posted
• A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa TherapyTerminatedNCT01927055Phase 3Results posted
• Study of Rifampicin in Multiple System AtrophyTerminatedNCT01287221Phase 3Results posted
• Nebivolol in the Supine Hypertension of Autonomic FailureCompletedNCT01044693Not applicableResults posted
• Lithium in Multiple System AtrophyTerminatedNCT00997672Phase 2Results posted
• Clinical Trial to Assess Efficacy, Safety, and Tolerability of Rasagiline Mesylate 1 mg in Patients With Multiple System Atrophy of the Parkinsonian Subtype (MSA-P)CompletedNCT00977665Phase 2Results posted
• Treatment of Multiple System Atrophy Using Intravenous ImmunoglobulinsCompletedNCT00750867Phase 2Results posted
• Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)CompletedNCT00738062Phase 3Results posted
• Augmenting Effects of L-DOPS With Carbidopa and EntacaponeTerminatedNCT00547911Phase 1/2Results posted
• High-Altitude Neurodegeneration Cohort (HANC) StudyWithdrawnNCT07657520
• A Phase 2 Study of YA-101 in Patients With Multiple System AtrophyActive, not recruitingNCT06848231Phase 2
• Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body DiseaseActive, not recruitingNCT06846658

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