Multiple Sclerosis, Chronic Progressive: all 244 studies
Page 2 of 3. Open to participants first (53), then studies with results posted, then the rest; newest registration first within each.
- PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPFCompletedNCT06683612Phase 1
- IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple SclerosisSuspendedNCT06677710Phase 1
- Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS)Active, not recruitingNCT06675864Phase 1/2
- A Real-world Study to Assess the Use of Siponimod in Spain to Treat Patients With Secondary Progressive Multiple SclerosisCompletedNCT06588387
- ABA-101 in Participants With Progressive Multiple SclerosisActive, not recruitingNCT06566261Phase 1
- Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 TherapiesCompletedNCT06526000
- A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple SclerosisActive, not recruitingNCT06451159Phase 1
- The Effects of In-phase Bilateral Exercise in People with Progressive Multiple SclerosisCompletedNCT06436131Not applicable
- The Synergistic Effects of AIH and FES in Persons With MSActive, not recruitingNCT06413602Not applicable
- A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple SclerosisCompletedNCT06395909
- KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple SclerosisActive, not recruitingNCT06384976Phase 2
- A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.Active, not recruitingNCT06372145Phase 3
- Evaluate the Safety and Feasibility of Allogeneic Mesenchymal Stem Cells in Patients With Multiple SclerosisCompletedNCT06360861Phase 1
- A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis PatientsActive, not recruitingNCT06292923Phase 2
- Effect of Ocrelizumab on Choroid Plexus Changes in Patients With PPMSCompletedNCT05974852
- Effect of Ocrelizumab on Cortical Lesion Accumulation in Patients With PPMS (ORATORIO-Cortical)CompletedNCT05974839
- Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And NeurodegenerationActive, not recruitingNCT05893225Phase 2
- Mayzent (Siponimod) Onboarding of Secondary Progressive Multiple Sclerosis (SPMS) Patients With MSGoCompletedNCT05826028
- Cognitive Reserve-building Activities in Multiple SclerosisCompletedNCT05691192Phase 2
- An Observational Biomarker Study in Multiple Sclerosis (MS) PatientsCompletedNCT05663853
- Transient and Immediate Motor Effects of Exercise in Progressive Multiple SclerosisStatus unknownNCT05562414Not applicable
- Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple SclerosisSuspendedNCT05441488Phase 3
- MUSCLE - Nordic Walking in MUltiple SCLErosisStatus unknownNCT05385731Not applicable
- Impact of Mayzent on aSPMS Patients in a Long-term NIS in ItalyCompletedNCT05376579
- Novel Imaging Markers in SPMSCompletedNCT05357833Early Phase 1
- Metformin Treatment in Progressive Multiple SclerosisCompletedNCT05349474Early Phase 1
- Functional Outcomes From Diets in Multiple SclerosisActive, not recruitingNCT05327322Not applicable
- The Influence of HIIT Versus MCT on Cardiorespiratory Fitness in PPMSStatus unknownNCT05229861Not applicable
- Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple SclerosisCompletedNCT05168384Phase 1/2
- Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple SclerosisActive, not recruitingNCT05122559Phase 2
- Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple SclerosisActive, not recruitingNCT05054140Phase 2
- Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MSWithdrawnNCT05029609Phase 1
- Hydroxychloroquine and Indapamide in SPMSStatus unknownNCT05013463Phase 2
- Sensitivity of Motor Assessment in MS - a Prospective Cohort StudyStatus unknownNCT04993274
- Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple SclerosisCompletedNCT04943289Phase 1
- Motor Asymmetry in Progressive Multiple Sclerosis PatientsCompletedNCT04918225
- Swiss Study of the Impact of Mayzent on SPMS Patients in a Long-term Non-interventional StudyTerminatedNCT04895202
- Effect of Variance on Error Correction During CouplingCompletedNCT04856384Not applicable
- Study of Mesenchymal Autologous Stem Cells as Regenerative Treatment for Multiple SclerosisActive, not recruitingNCT04749667Phase 1/2
- Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculographyCompletedNCT04705610Not applicable
- ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple SclerosisActive, not recruitingNCT04695080Phase 2/3
- Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple SclerosisActive, not recruitingNCT04688788Phase 3
- Long Term Special Drug Use-results Surveillance for Mayzent in SPMS PatientsCompletedNCT04593927
- Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS PatientsCompletedNCT04550650Not applicable
- Aerobic Exercises for Multiple SclerosisCompletedNCT04545372Not applicable
- A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple SclerosisActive, not recruitingNCT04544449Phase 3
- Managed Access Program (MAP) for Patients Diagnosed With Secondary Progressive Multiple Sclerosis With Active DiseaseNo longer availableNCT04540861
- Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)CompletedNCT04458051Phase 3
- Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)CompletedNCT04289909Not applicable
- Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS).Status unknownNCT04260711Not applicable
- Acceptance Based Telephone Support When Transitioning to SPMSCompletedNCT04239664Not applicable
- Phase II Clinical Trial of OCH-NCNP1CompletedNCT04211740Phase 2
- Serum Neurofilaments and GFAP in Atypical Multiple SclerosisCompletedNCT04201470Not applicable
- Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple SclerosisCompletedNCT04120675Not applicable
- A Non-Interventional Pilot Study to Explore the Role of Gut Flora in DiseaseSuspendedNCT04031469
- 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.CompletedNCT03993171Phase 2
- Behavioural Activation for Low Mood in Multiple SclerosisCompletedNCT03935529Not applicable
- Study to Assess the Safety and Efficacy of an IT Administration of SCM-010 in SPMSWithdrawnNCT03696485Phase 1/2
- Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive RehabilitationCompletedNCT03679468Not applicable
- Cortical Lesions in Patients With Multiple SclerosisCompletedNCT03653585
- Evaluation of the Incidence of Relapses in Patients With Biotin-treated Progressive Multiple SclerosisStatus unknownNCT03552211
- A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple SclerosisActive, not recruitingNCT03523858Phase 3
- Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple SclerosisCompletedNCT03493841Phase 1
- Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation ProgrammeCompletedNCT03471338Not applicable
- Cognition Evolution and MRI Markers in PPMS Patients on 2 YearsCompletedNCT03455582Not applicable
- The Effect of Neurorehabilitation Therapy on Postural Control, Mobility and Quality of Life in Multiple Sclerosis PatientsCompletedNCT03424538Not applicable
- Multiple Sclerosis-Simvastatin Trial 2CompletedNCT03387670Phase 3
- Safety and Efficacy of Monthly Long-acting IM Injection of 25mg or 40 mg GA Depot in Subjects With PPMSTerminatedNCT03362294Phase 2
- Comparison of Clinical Effects of Rituximab and Glatiramer Acetate in Secondary Progressive Multiple Sclerosis PatientsCompletedNCT03315923Phase 2/3
- Study to Assess Effect and Safety of High Dose of Biotin (Qizenday®) in Progressive Multiple SclerosisCompletedNCT03302806
- Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple SclerosisTerminatedNCT03283826Phase 1/2
- Safety Study of Human Neural Stem Cells Injections for Secondary Progressive Multiple Sclerosis PatientsCompletedNCT03282760Phase 1
- Neural Stem Cell Transplantation in Multiple Sclerosis PatientsCompletedNCT03269071Phase 1
- Armergometry to Improve Mobility in MSStatus unknownNCT03147105Not applicable
- Medication Usage and Patient Reported Outcomes Evaluation Via myBETAapp in Patients With Multiple Sclerosis Treated With Betaferon: a Pilot StudyCompletedNCT03134573
- Evidence Based Patient Information and Smartphone Accelerometry to Enhance Physical Activity in MSStatus unknownNCT03114293Not applicable
- Video Game-based Therapy for Arm Weakness In Progressive Multiple SclerosisCompletedNCT03094364Not applicable
- A Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple SclerosisCompletedNCT02977533Phase 1
- Dimethyl Fumarate Treatment of Primary Progressive Multiple SclerosisCompletedNCT02959658Phase 2
- The Effect of High Intensity Interval Training on Cardiovascular Fitness in People With Progressive Multiple Sclerosis.CompletedNCT02950454Not applicable
- Hydroxychloroquine in Primary Progressive Multiple SclerosisCompletedNCT02913157Phase 2
- Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm StudyStatus unknownNCT02644044Early Phase 1
- A Study to Characterize Subcutaneous or Intravenous Alemtuzumab in Patients With Progressive Multiple SclerosisCompletedNCT02583594Phase 1
- Study by Magnetic Resonance Imaging in the Progressive Forms of Multiple SclerosisTerminatedNCT02580669Not applicable
- Access, Use and Opinions of Physiotherapy and Rehabilitation Services of People With Progressive MS in the UK.CompletedNCT02559765
- Mitochondrial Dysfunction and Disease ProgressionCompletedNCT02549703
- Intrathecal Rituximab in Progressive Multiple SclerosisCompletedNCT02545959Phase 2
- Open-label Study of Liothyronine in MSCompletedNCT02506751Phase 1
- Autologous Mesenchymal Stromal Cells for Multiple SclerosisCompletedNCT02495766Phase 1/2
- Rotating Frame Relaxation Imaging in Patients With Multiple SclerosisCompletedNCT02403570
- Mechanistic Studies of Phase III Trial With BAF312 in Secondary Progressive Multiple SclerosisCompletedNCT02330965
- Multi-Center Study Safety of Adipose Derived Mesenchymal Stem Cells for the Treatment of Multiple SclerosisTerminatedNCT02326935Phase 1
- A Long-term Follow-up Study Of Multiple Sclerosis Patients Who Participated In Genzyme-sponsored Studies of GZ402668CompletedNCT02313285
- Domperidone in Secondary Progressive Multiple Sclerosis (SPMS)CompletedNCT02308137Phase 2
- Imaging of Intracerebral Inflammation in MSCompletedNCT02305264Not applicable
- Treating New Learning and Memory Deficits in Progressive Multiple Sclerosis (MS)CompletedNCT02301247Not applicable
- A First-in-human, Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple SclerosisCompletedNCT02282826Phase 1
- Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MSStatus unknownNCT02273635Phase 1/2
- Improving Cognitive Aptitudes With tDCS in Patients With Multiple SclerosisTerminatedNCT02266121Not applicable
- A Phase 1 Trial of Intrathecal Rituximab for Progressive Multiple Sclerosis PatientsCompletedNCT02253264Phase 1