An interventional study of High intensity interval training and Continuous moderate exercise in Multiple Sclerosis, Progressive, sponsored by University of Glasgow. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-10-25.
Sponsored by University of Glasgow · Not applicable, Interventional, and Treatment
This is a pilot trial to explore the cardiovascular of eight weeks of twice weekly high intensity interval training in people with progressive multiple sclerosis. A control group of people with progressive multiple sclerosis will undergo continuous moderate intensity exercise, twice weekly for 8 weeks.
This is a pilot trial to explore the cardiovascular of eight weeks of twice weekly high intensity interval training in people with progressive multiple sclerosis. A control group of people with progressive multiple sclerosis will undergo continuous moderate intensity exercise, twice weekly for 8 weeks.
The training program will entail 6x1.5 minute intervals working at 80-95% heart rate max on a cycle ergometer. Each interval will be interspersed with 1.5 minutes of working rest at a light resistance of the participant's choosing.
The continuous moderate intensity exercise program will entail 20 minutes on a cycle ergometer working at 60-70% heart rate max.
242 studies on the registry are indexed under Multiple Sclerosis, Chronic Progressive; 55 are open to participants now.
This study's enrollment of 12 is below the median of 51 across 189 interventional studies indexed under Multiple Sclerosis, Chronic Progressive.
Browse Multiple Sclerosis, Chronic Progressive studies →University of Glasgow is the lead sponsor of 145 studies on the registry; 21 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
8 weeks of twice weekly high intensity interval training. Session protocol: 2 minute warm up at nominal resistance on cycle ergometer, 6 six intervals of 80-95% heart rate max interspersed with 6 intervals of 1.5 minute working rest. Then 3 minutes cool down.
Other: High intensity interval training
8 weeks of twice weekly continuous moderate intensity exercise. Session protocol: 2 minutes warm up at nominal resistance on cycle ergometer, 20 minutes at 60-70% heart rate max. Then 3 minutes cool down.
Other: Continuous moderate exercise
1.5 min intervals at 80-95% heart rate max on cycle ergometer 1.5 min intervals at nominal resistance on cycle ergometer
20 min at 60-70% heart rate max on cycle ergometer
heart rate max
Maximal heart rate elicited during a maximal exertion test
Time frame: 8 weeks
Resting blood pressure
Time frame: 8 weeks
Resting heart rate
Time frame: 8 weeks
Brain derived neurotrophic factor
Hormone important for brain growth and protection
Time frame: 8 weeks
Lactate
Waste materials from exercise in blood
Time frame: 8 weeks
Lipoprotein profile
Indication of how much good and how much bad cholesterol is in blood
Time frame: 8 weeks
MSIS-29 version 2
Questionnaire giving physical and psychological impact of MS
Time frame: 8 weeks
Hospital anxiety and depression scale
Questionnaire giving a score of depression and anxiety
Time frame: 8 weeks
Timed 25 foot walk test
Measure of walking speed
Time frame: 8 weeks
Symbol digit modalities test
Measure of mental processing speed
Time frame: 8 weeks
Fatigue severity scale
Questionnaire which gives measure of fatigue.
Time frame: 8 weeks
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Multiple Sclerosis, Chronic Progressive →