Meningioma clinical trials
The registry lists 255 studies for Meningioma across more than 10 countries. 85 are recruiting or about to start. 126 of them are mainly about Meningioma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
National Cancer Institute (NCI) (12) · Central Hospital, Nancy, France (8) · Wake Forest University Health Sciences (7) · Beijing Tiantan Hospital (6) · Massachusetts General Hospital (5) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (4) · Northwestern University (4) · Weill Medical College of Cornell University (4)
What is being tested here
Drugs under test in Meningioma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Lutetium Lu 177 dotatate | 4 | 0 | 5 |
| Abemaciclib | 2 | 0 | 3 |
| AZD 6244 | 2 | 0 | 3 |
| Luvometinib | 2 | 0 | 2 |
| Everolimus | 1 | 0 | 5 |
| ONC206 | 1 | 0 | 2 |
| Dexmedetomidine | 1 | 0 | 1 |
| Ceritinib | 1 | 0 | 1 |
| Lutetium-177 | 1 | 0 | 1 |
| HhAntag691 | 1 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 7 open · Immune checkpoint inhibitors 2 open · mTOR inhibitors 1 open · Angiogenesis inhibitors 6 · Antimetabolites 6
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jun 2027Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery · Phase 3 · NRG Oncology
- Dec 2026Cabozantinib for Patients With Recurrent or Progressive Meningioma · Baptist Health South Florida
- Dec 2026Robot-Assisted Neurovascular Intervention · Navigantis Inc.
- Dec 2026Long-Term Longitudinal QoL in Patients Undergoing EEA · Ohio State University
- Dec 2026DOTATATE PET for Meningioma Radiation Planning · British Columbia Cancer Agency
- Dec 2026RYZ101 for the Treatment of Progressive or Recurrent Intracranial Meningioma · Joshua Palmer
- Dec 2026Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-satoreotide · University Hospital, Basel, Switzerland
- Jan 2027Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE · Weill Medical College of Cornell University
- Jan 2027Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors · Jonsson Comprehensive Cancer Center
- Mar 2027Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma · National Cancer Institute (NCI)
Who these studies take
Of the 66 Meningioma studies recruiting now, 43 (65%) set no upper age limit and 9 (14%) stop at 75 or younger. 8 (12%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 6 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (8%) | 5 (8%) |
| 18 | 65 (98%) | 64 (97%) |
| 30 | 66 (100%) | 65 (98%) |
| 40 | 65 (98%) | 64 (97%) |
| 50 | 65 (98%) | 64 (97%) |
| 65 | 65 (98%) | 64 (97%) |
| 75 | 58 (88%) | 57 (86%) |
| 85 | 50 (76%) | 49 (74%) |
Across all 255 studies, recruiting or not: 17% stop at 75 or younger and 10% at 65; 17% take children; <1% are for women only and <1% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Meningioma studies take
Of 37 phase 2 interventional studies under Meningioma, half reached primary completion within 62 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 62 mo41–108 · 37 studies | — | — |
| Observational | 106 mo60–… · 29 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered2
- Evaluation of Immunohistochemical Expression of Phosphohistone H3 (PHH3) in MeningiomaNov 9, 2026NCT07926633
- Ceritinib Treatment for Recurrent MeningiomasOct 23, 2026NCT07893197
Studies
Recruiting first, then most recently updated. Showing 50 of 255. Browse all 255 → or search them.
- Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior TreatmentRecruitingNCT06955169Phase 21 country
- DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial)Not yet recruitingNCT07398066Not applicable
- Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive MeningiomasRecruitingNCT02523014Phase 21 country
- 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.RecruitingNCT04081701Phase 41 country
- A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 MeningiomaRecruitingNCT07533942Phase 21 country
- Selumetinib for NF2-Related SchwannomatosisNot yet recruitingNCT07707947Phase 21 country
- A Study of Zanzalintinib in Participants With Recurrent or Progressive MeningiomaRecruitingNCT07428616Phase 21 country
- Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)RecruitingNCT04374305Phase 21 country
- Ceritinib Treatment for Recurrent MeningiomasNot yet recruitingNCT07893197Phase 21 country
- IN10018 in Combination With Dalpiciclib for Progressive MeningiomasRecruitingNCT07652762Phase 11 country
- Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical ProceduresRecruitingNCT07493447Early Phase 11 country
- Natural History Study of Patients With Neurofibromatosis Type 2RecruitingNCT005983511 country
- Sonography-guided Resection of Brain Mass LesionsRecruitingNCT05484245Not applicable1 country
- Intraoperative Brain Shift Calculation StudyRecruitingNCT05477680Not applicable1 country
- Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncologyRecruitingNCT046484621 country
- Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation TherapyRecruitingNCT04082520Phase 21 country
- Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive TumorsRecruitingNCT05636618Phase 1/21 country
- Regorafenib for Recurrent Meningioma (MIRAGE Trial)RecruitingNCT06275919Phase 21 country
- Liquid Biopsy Evaluation and Repository Development at Princess MargaretRecruitingNCT037023091 country
- Pharmacoscopy for Patients With Refractory Primary Brain TumorsRecruitingNCT06804655Phase 21 country
- Preoperative Embolization for Highly Vascular Brain TumorsNot yet recruitingNCT07823985Not applicable
- Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine DepartmentRecruitingNCT04104529Not applicable1 country
- UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial LesionsRecruitingNCT04343157Phase 21 country
- Adjuvant Hypofractionated Stereotactic Radiosurgery for Intermediate-risk MeningiomaRecruitingNCT06557512Not applicable1 country
- Comparing Radiation After Surgery to Observation After Surgery in Patients With Clinical Low-Risk, Molecular High-Risk Meningioma, and Evaluating Observation After Surgery in Patients With Clinical and Molecular Low-Risk MeningiomaNot yet recruitingNCT07785687Phase 3
- Feasibility of Acquiring Hyperpolarized Imaging in Patients With MeningiomaRecruitingNCT06014905Phase 11 country
- RYZ101 for the Treatment of Progressive or Recurrent Intracranial MeningiomaRecruitingNCT07150806Phase 1/21 country
- Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)RecruitingNCT044273841 country
- Embolization for MeningiomaRecruitingNCT05416567Not applicable1 country
- Lutathera for Treatment of Recurrent or Progressive High-Grade CNS TumorsRecruitingNCT05278208Phase 1/21 country
- Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2)Not yet recruitingNCT07713745Phase 21 country
- Luvometinib in Combination With Serplulimab for NF2-Related TumorsNot yet recruitingNCT07708285Phase 1/21 country
- Search for Circulating Tumour Cells in the Blood and/or Cerebrospinal Fluid in Patients With Recurrent Aggressive Meningiomas: Proof-of-concept StudyRecruitingNCT07398170Not applicable1 country
- Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical TrialRecruitingNCT06126588Phase 21 country
- 177Lu-DOTATATE for Recurrent MeningiomaRecruitingNCT06326190Phase 26 countries
- Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT PatientsRecruitingNCT055761031 country
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/21 country
- A Phase III Study of SYHA1813 for Recurrent or Progressive High-Grade MeningiomasNot yet recruitingNCT07613450Phase 3
- Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial TumorsRecruitingNCT074116901 country
- Cognitive Status After Removal of Skull Base MeningiomaRecruitingNCT046356571 country
- Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted SuturesRecruitingNCT07413796Not applicable1 country
- Diagnostic Performance and Quantitative Analysis of [18F]FET PET in Brain TumoursNot yet recruitingNCT07599917
- Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With MeningiomaRecruitingNCT074187751 country
- Cabozantinib for Patients With Recurrent or Progressive MeningiomaRecruitingNCT05425004Phase 21 country
- NK Cell Therapy for Malignant Solid Brain TumorsRecruitingNCT07552233Not applicable1 country
- ITM11 Expanded Access ProgramAvailableNCT07497984
- Abemaciclib in Newly Diagnosed Meningioma PatientsRecruitingNCT05940493Phase 21 country
- Plasma Extracellular Vesicles in Meningioma PatientsRecruitingNCT06104930Not applicable1 country
- Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATERecruitingNCT06377371Phase 41 country
- Measurement of PSMA Expression in Vivo in Recurrent Meningiomas by PET Imaging: a Preliminary Study to a Therapeutic Trial Using Radioligand Therapy (RLT)Not yet recruitingNCT07428213Not applicable1 country