Macular Degeneration: all 1,490 studies

Page 3 of 15. Open to participants first (208), then studies with results posted, then the rest; newest registration first within each.

• A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular DegenerationRecruitingNCT03178149Phase 1
• Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable
• Aflibercept in Recurrent or Persistent CNVRecruitingNCT02669953
• OCT Angiography in Wet AMDRecruitingNCT02253030
• Analysis of Biomarkers From Patients With Chorioretinal DiseasesRecruitingNCT02026843
• High Resolution Retinal ImagingRecruitingNCT01866371
• National Eye Institute Biorepository for Retinal DiseasesRecruitingNCT01496625
• Cell Collection to Study Eye DiseasesRecruitingNCT01432847
• Retinal Fundus Flavoprotein Fluorescence in Age Related Macular DegenerationCompletedNCT06381596Not applicableResults posted
• A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedNCT06190093Phase 3Results posted
• A Study to Evaluate the Usability of the SB11 PFS in Subjects With Wet AMD or Macular Oedema Secondary to RVOCompletedNCT06176963Phase 2Results posted
• COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic AtrophyCompletedNCT05961332Not applicableResults posted
• A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD)CompletedNCT05919693Phase 1/2Results posted
• Cool vs Room-temperature Artificial TearsCompletedNCT05832996Phase 4Results posted
• Suprachoroidal Sustained-Release OXU-001 Compared to Intravitreal Ozurdex® in the Treatment of Diabetic Macular EdemaCompletedNCT05697809Phase 2Results posted
• Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp ConfigurationsTerminatedNCT05686421Not applicableResults posted
• Clinical Evaluation of VeriSee AMD in Screening for Age-Related Macular DegenerationCompletedNCT05593913Results posted
• Safety Study of Zimura in Combination With Anti-VEGF Therapy in Patients With Neovascular AMDTerminatedNCT05571267Phase 2Results posted
• A Study in Patients With Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema to Evaluate the Safety of the Faricimab Prefilled SyringeCompletedNCT05569148Phase 3Results posted
• Avacincaptad Pegol Open-Label Extension for Patients With Geographic AtrophyCompletedNCT05536297Phase 3Results posted
• A Study to Learn How Well Aflibercept Injected Into the Eye Works and How Safe it is When Given in Customized Treatment Intervals in Patients With an Eye Disease Called Neovascular Age-related Macular Degeneration After Start of TreatmentTerminatedNCT05473715Phase 4Results posted
• Scotoma Perimetry Oculomotor TrainingCompletedNCT05456581Not applicableResults posted
• Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Vial KitCompletedNCT05282004Phase 3Results posted
• Safety, Tolerability, and Efficacy Study of UBX1325 in Patients With Neovascular Age-Related Macular Degeneration (ENVISION)CompletedNCT05275205Phase 2Results posted
• Study to Evaluate the Safety and Effectiveness of Intravitreal Injections (IVI) of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD)CompletedNCT05269966Phase 4Results posted
• The Moran AMD Genetic Testing Assessment StudyCompletedNCT05265624Phase 2Results posted
• Study of the Safety of Use of Intravitreal SOK583A1 Provided in a Prefilled SyringeCompletedNCT05161806Phase 3Results posted
• Extension Study to Evaluate the Long-term Outcomes of Subjects in the CLS-AX CLS1002-101 StudyCompletedNCT05131646Results posted
• Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD SubjectsCompletedNCT04984590Results posted
• A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)CompletedNCT04964089Phase 3Results posted
• RBM-007 in Treatment naïve Exudative Age-related Macular DegenerationCompletedNCT04895293Phase 1/2Results posted
• Phase III Study Assessing the Efficacy, Safety and Immunogenicity of SOK583A1 Versus Eylea® in Patients With Neovascular Age-related Macular DegenerationCompletedNCT04864834Phase 3Results posted
• Study of Innovative Multimodal Imaging Biomarkers to Predict Anatomical Outcome in Naive Patients With wAMD Treated With Brolucizumab.CompletedNCT04774926Phase 4Results posted
• OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD)TerminatedNCT04757636Phase 3Results posted
• Safety and Bioactivity of AXT107 in Subjects With Neovascular Age-Related Macular DegenerationTerminatedNCT04746963Phase 1/2Results posted
• A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular DegenerationTerminatedNCT04684394Phase 2Results posted
• Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular DegenerationCompletedNCT04679935Phase 4Results posted
• A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular DegenerationCompletedNCT04640272Phase 2Results posted
• A Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationTerminatedNCT04607148Phase 2Results posted
• An Extension Study Assessing the Efficacy and Safety of Brolucizumab in a Treat-to-Control Regimen in Patients With Neovascular Age-related Macular Degeneration Who Have Completed the CRTH258A2303 (TALON) StudyCompletedNCT04597632Phase 3Results posted
• A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal DisordersCompletedNCT04516278Phase 3Results posted
• A Study to Comparing SCD411 and Eylea® in Subjects With Wet Age-related Macular Degeneration (AMD)CompletedNCT04480463Phase 3Results posted
• A Study to Compare SB15 (Proposed Aflibercept Biosimilar) to Eylea in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedNCT04450329Phase 3Results posted
• A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)CompletedNCT04435366Phase 3Results posted
• Sildenafil for Treatment of Choroidal IschemiaCompletedNCT04356716Phase 2Results posted
• A Study to Assess the Efficacy and Safety of AKST4290 With Aflibercept in Patients With Newly Diagnosed nAMDCompletedNCT04331730Phase 2Results posted
• A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea®) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD]CompletedNCT04270747Phase 3Results posted
• Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular DegenerationCompletedNCT04264819Phase 3Results posted
• A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular DegenerationCompletedNCT04239027Phase 3Results posted
• A Phase II Study of RBM-007 Alone and RBM-007 With Eylea® in Subjects With Wet Age-related Macular DegenerationCompletedNCT04200248Phase 2Results posted
• Advancing Understanding of Transportation OptionsCompletedNCT04141891Not applicableResults posted
• Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular DegenerationCompletedNCT04126317Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.TerminatedNCT04049266Phase 2/3Results posted
• Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Chinese Patients With Neovascular Age-Related Macular DegenerationCompletedNCT04047472Phase 3Results posted
• Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)CompletedNCT04005352Phase 3Results posted
• A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic AtrophyTerminatedNCT04002310Phase 1Results posted
• A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)TerminatedNCT03972709Phase 2Results posted
• Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMDCompletedNCT03954626Phase 3Results posted
• A Depot Formulation of Sunitinib Malate (GB-102) Compared to Aflibercept in Subjects With Wet AMDCompletedNCT03953079Phase 2Results posted
• Global Atrophie Biomarker Evaluation Study (GABiE)TerminatedNCT03935126Results posted
• Study of the Safety of Brolucizumab 6 mg in Prefilled Syringe in Patients With Neovascular Age Related Macular DegenerationCompletedNCT03930641Phase 3Results posted
• ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GACompletedNCT03891875Phase 2Results posted
• A Study to Assess the Safety, Tolerability and Effectiveness of MT-0814 for the Treatment of Age-related Macular DegenerationTerminatedNCT03869684Phase 2Results posted
• A Study to Test Different Doses of BI 836880 in Patients With an Eye Disease Called Wet Age-related Macular Degeneration (wAMD)CompletedNCT03861234Phase 1/2Results posted
• FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMDTerminatedNCT03846193Phase 1/2Results posted
• Phase 2/3 Study of ALK-001 in Geographic AtrophyCompletedNCT03845582Phase 2/3Results posted
• A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedNCT03834753Phase 3Results posted
• Comparing the Efficacy and Safety of Biosimilar Candidate Xlucane Versus Lucentis® in Patients With nAMDCompletedNCT03805100Phase 3Results posted
• Visual Enhancement Device in Low Vision PatientsTerminatedNCT03794752Not applicableResults posted
• Safety and Efficacy of Emixustat in Stargardt DiseaseCompletedNCT03772665Phase 3Results posted
• Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF InjectionsTerminatedNCT03710564Phase 3Results posted
• A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular DegenerationCompletedNCT03677934Phase 3Results posted
• RBM-007 in Subjects witH ExudatIve Age-related Macular DegenerationCompletedNCT03633084Phase 1/2Results posted
• Evaluate the Therapeutic Effects and Safety of ALK4290 in Patients With Refractory Wet Age-Related Macular DegenerationCompletedNCT03558074Phase 2Results posted
• Evaluate the Effects and Safety of ALK4290 in Patients With Newly Diagnosed Wet Age-Related Macular DegenerationCompletedNCT03558061Phase 2Results posted
• A Study to Evaluate Abicipar Pegol for Safety and Treatment Effect in Participants With Neovascular Age-related Macular Degeneration (AMD)CompletedNCT03539549Phase 2Results posted
• A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationCompletedNCT03525613Phase 3Results posted
• Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationCompletedNCT03525600Phase 3Results posted
• Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark AdaptationCompletedNCT03478878Early Phase 1Results posted
• Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark AdaptationCompletedNCT03478865Early Phase 1Results posted
• Pegcetacoplan (APL-2) in Neovascular AMDTerminatedNCT03465709Phase 1/2Results posted
• Open-Label Study of Intravitreal ICON-1 in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)TerminatedNCT03452527Phase 2Results posted
• Alpha MSH in Ocular DiseaseCompletedNCT03451578Not applicableResults posted
• Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMDCompletedNCT03386474Phase 3Results posted
• ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD)CompletedNCT03362190Phase 2Results posted
• Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)CompletedNCT03322930Results posted
• BCI and Evaluation of Visual and Task Performance in Subjects With Eye DiseasesCompletedNCT03318549Not applicableResults posted
• Evaluation of the Effect of Intravitreal Injections of Anti-VEGF on Macular Perfusion in Diabetic Patients Using OCTACompletedNCT03246152Phase 4Results posted
• Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration SubjectsCompletedNCT03211234Phase 2Results posted
• A Study to Compare SB11 (Proposed Ranibizumab Biosimilar) to Lucentis in Subjects With Neovascular Age-related Macular Degeneration (AMD)CompletedNCT03150589Phase 3Results posted
• An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal VasculopathyCompletedNCT03117634Phase 4Results posted
• Safety and Tolerability of RGX-314 (Investigational Product) Gene Therapy for Neovascular AMD TrialCompletedNCT03066258Phase 1/2Results posted
• Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular DegenerationCompletedNCT03038880Phase 2Results posted
• Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular DegenerationCompletedNCT03034772Phase 2/3Results posted
• Pharmacodynamic Study of Emixustat Hydrochloride in Subjects With Macular Atrophy Secondary to Stargardt DiseaseCompletedNCT03033108Phase 2Results posted
• Dose Ranging Study of Carbidopa-levodopaCompletedNCT03023059Phase 2Results posted
• Carbidopa-levodopa in Neovascular AMDCompletedNCT03022318Phase 2Results posted
• The IAI-OCTA Study; a Study of OCT-Angiography Analysis EfficacyCompletedNCT03022292Phase 4Results posted
• Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal InjectionsCompletedNCT02951351Not applicableResults posted
• Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD)CompletedNCT02914639Phase 1/2Results posted

← Macular Degeneration overview