ClinicalTrials.gg
Sign In

Machado-Joseph Disease clinical trials

The registry lists 33 studies for Machado-Joseph Disease across more than 10 countries. 5 are recruiting or about to start. 30 of them are mainly about Machado-Joseph Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

Get an email when these change. Save the Machado-Joseph Disease studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies
See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
16
Status unknown
6
Recruiting
3
Not yet recruiting
2
Active, not recruiting
2
Terminated
2

Phase

Phase 2
9
Phase 3
4
Phase 1
2

Where

United States
14
Brazil
6
Israel
5
China
4
United Kingdom
3
Germany
3

Who runs them

Hospital de Clinicas de Porto Alegre (5) · First Affiliated Hospital of Fujian Medical University (2) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (2) · National University of Malaysia (2) · Vico Therapeutics B. V. (1) · Lauren Moore (1) · University of Mississippi Medical Center (1) · Meir Medical Center (1)

What is being tested here

Drugs under test in Machado-Joseph Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Troriluzole022
Trehalose002
Lithium Carbonate011
Varenicline001
SLS-005011
Phenylbutyric acid001

Coming up

1phase 3 study under way
2studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2

Who these studies take

Of the 3 Machado-Joseph Disease studies recruiting now, 2 (67%) set no upper age limit and 1 (33%) stop at 75 or younger. 2 (67%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (33%) take healthy volunteers.

Recruiting studies that take each age, of 3
AgeWomenMen
102 (67%)2 (67%)
182 (67%)2 (67%)
303 (100%)3 (100%)
403 (100%)3 (100%)
503 (100%)3 (100%)
652 (67%)2 (67%)
752 (67%)2 (67%)
852 (67%)2 (67%)

Across all 33 studies, recruiting or not: 36% stop at 75 or younger and 12% at 65; 21% take children; 3% are for women only and 0% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 33 of 33. search them.